Ultrasound guided paracentesis and thoracentesis for hospitalists Deepti S Rao Thanks • Jason Cohen • Michel Boivin Objectives After this session you should be able to: 1. Explain the rationale behind using ultrasound in thoracentesis and paracentesis 2. Understand the objectives, outcomes and activities proposed in my research project 3. Discuss the feasability of doing this project in this group of hospitalists. Ultrasound in procedures • Central lines – Lots of literature including increased patient safety • Thoracentesis/Paracentesis – Not much literature Ultrasound in thoracentesis • Risk of complications up to 19% • Grogan et al. Archiv Int med, 1990 – 0% vs 29% reduction in pneumothorax when ultrasound used for needle placement • Raptopoulos et al. Am Journ Roent, 1991. – 3% vs 18% – Irregardless of size of effusion, whether thoracentesis was diagnostic or therapeutic, and whether tap was dry. Ultrasound in thoracentesis ARCH INTERN MED/VOL 170 (NO. 4), FEB 22, 2010 • Table 3. Unadjusted Odds Ratios for Pneumothorax by Procedural or Patient Factor (Direct Comparisons) • • Variable for Pneumothorax • • • • • • • Procedural Factors Ultrasonography vs no ultrasonography Experienced operator vs inexperienced Therapeutic thoracentesis vs diagnostic Larger needle or catheter vs small needle 2 Needle passes vs 1 pass Follow-up thoracentesis vs initial • • • Periprocedural Factors Aspiration of air vs none Periprocedural symptoms vs none • • • • • • • Patient Factors Large effusion size vs small Male vs female sex ICU inpatient location vs non-ICU inpatient Non-ICU inpatient location vs outpatient Mechanical ventilation vs not Loculated pleural effusion vs nonloculated • • Abbreviation: ICU, intensive care unit. Only studies that reported results for both the presence and absence of a variable. No. of Studies 6 4 12 7 3 3 2 3 7 3 3 2 2 3 No. of Patients With(Without) Variable Odds Ratio (95% Confidence Interval) 654 (1026) 308 (622) 1048 (1323) 700 (1178) 145 (580) 377 (993) 19 (661) 57 (1504) 758 (697) 272 (220) 142 (620) 213 (448) 100 (589) 106 (377) 0.3 (0.2-0.7) 0.7 (0.2-2.3) 2.6 (1.8-3.8) 2.5 (1.1-6.0) 2.5 (0.3-20.1) 1.1 (0.3-3.6) 104.0 (2.0-5355.0) 26.6 (2.7-262.5) 1.3 (0.8-1.9) 0.8 (0.3-1.7) 0.9 (0.4-1.8) 1.0 (0.5-2.0) 4.0 (0.95-16.8) 0.7 (0.3-1.7) Ultrasound in thoracentesis • “X marks the spot” after a delay not associated in a reduction in pneumothorax rate – Raptopoulos et al. Am J of Roent, 1991 Ultrasound in thoracentesis • Failed thoracentesis – 58% of clinically attempted dry taps had needle insertion sites below the diaphragm – Fluid can be successfully obtained in up to 88% of patients who had failed clinically directed thoracentesis – Ultrasound increased rate of accurate site selection 26% and decreased number of dangerous needle insertions by 10% (Weingardt, J Clin Ultra, 1994) (Kopman, Chest, 2006.) (Diacon, Chest 2003) Ultrasound in thoracentesis • In summary, the complication rate for thoracentesis is high and ultrasound can decrease that risk Ultrasound in paracentesis • Complications low (up to 2.7%) – Runyon, Arch Int Med, 1986 • Ultrasound may have a role in identifying smaller pockets of fluid – Physical exam can fail to find small amounts of fluid or the most easily accessible pocket of fluid – Ultrasound can detect pockets of fluid as small as 100cc Ultrasound in paracentesis • Ultrasound decreased the number of unsuccessful attempts by demonstrating which patients did not have sufficient ascites to tap – Nazeer, etal. American Journal of Emergency Medicine, 2005. So why do we want to do this? • Patient safety • Patient comfort (increased success in performing) • Resident learning and comfort • Basis for eventual simulation based procedural training Resident comfort Huang etal, The American Journal of Med, 2006 • • Table 3 Lack of comfort, by procedure Lack of comfort with All n 527 • • • • • • • • • • • • • • • • • • • • • • • Indications and contraindications, n (%) Obtaining consent, n (%) Anatomy, n (%) Equipment, n (%) Sterile technique, n (%) Patient positioning, n (%) Interpreting the results, n (%) 11 (2.1%) 10 (1.9%) 28 (5.3%) 45 (8.5%) 7 (1.3%) 14 (2.7%) Central line n 268 Lumbar puncture n 95 6 (2.2%) 5 (1.9%) 19 (7.1%) 19 (7.1%) 6 (2.2%) 6 (2.2%) 25 (4.7%) 16 (6.0%) 5/206 (2.4%) 3/89 (3.4%) Paracentesis n 81 0 (0.0%) 2 (2.1%) 3 (3.2%) 5 (5.3%) 0 (0.0%) 4 (4.2%) 2 (2.1%) Thoracentesis n 93 Pvalue* 0 (0.0%) 2 (2.5%) 1 (1.2%) 10 (12.3%) 1 (1.2%) 2 (2.5%) 5 (6.0%) 1 (1.2%) 5 (6.0%) 11 (13.3%) 0 (0.0%) 2 (2.4%) 3 (3.7%) .017 .935 .040 .001 .494 .191 4 (4.8%) .493 2/65 (3.1%) .884 Being supervised, n/total (%)† 0/27 (0.0%) 0/25 (0.0%) Being unsupervised, n/total (%)‡ 119/321 (37.1%) 70/179 (39.1%) 23/68 (33.8%) 14/56 (25.0%) 12/18 (66.7%) .001 Managing complications, n (%) 186 (35.3%) 87 (32.5%) 32 (33.7%) 28 (34.6%) 39 (47.0%) .003 Mean number of aspects with lack of comfort, n (SD, range) 0.85 (1.1, 0-8) 0.88 (1.2, 0-8) 0.75 (0.1, 0-4) 0.75 (1.0, 0-4) 0.98 (1.1, 0-6) Thoracentesis – Iatrogenic pneumothorax • AHRQ Healthcare Cost & Utilization Project, Nationwide Inpatient Sample database, 2000 • 7.45 million hospital d/c abstracts • 994 short-term acute care hospitals • 28 states • JMH: July 2007 through June 2008 • Procedure team: July 2007 through June 2008 Number Incidence Rate National n/a 2.68% JMH 286 5.94% Procedure team 89 1.12%* 15 Healthcare toll per episode • 4 – 7 excess days in hospital length of stay • $17,000 - $45,000 in excess cost • 1% - 14% excess mortality 16 In summary • Ultrasound decreases complication rates in thoracentesis and may reduce unnecessary procedures in paracentesis. • This can reduce risk to our patients. • This is a skill our residents should have exposure to. Curricula for teaching ultrasound • Didactics – Ultrasound physics – Machine usage – Indications – Anatomy • Supervised scanning – Hand on hand Judging competency • Multiple choice testing • Observed scanning – 5-10 scans ACEP: 3-4 hours didactics, 2-4 hours supervised scanning Research question • Can a multi-part learning curriculum aimed at inpatient medicine attendings increase the competency of internal medicine physicians in performing ultrasound guided paracentesis and thoracentesis? And will this increased competency lead to an increased use of ultrasound for these procedures on the medicine wards? Secondary objectives • Will this increase resident exposure/teaching to ultrasound • Will this decrease complication rates Outcomes Outcome Measure Learning activities Competence in ultrasound guided para/thora Pre- and post-multiple choice test on ultrasound technology/anatomy Direct observation of working machine and id fluid time 0, 1 month and 1 year Increased use of ultrasound on the wards Monthly questionnaire of attendings Chart review Increased teaching/exposure of residents to ultrasound Monthly questionnaire of attendings Pre- and post- tests of residents on ward rotations Decrease in complications Chart reviews pre and post intervention. Didactic sessions/ online training Hands on trainings Timeline Timeline August 2011 Attend resident Thursday school sessions—Rao Start attending scheduled scanning session with Boivin—Rao September 2011 Work with medical student to obtain HRRC approval and obtain medical record numbers and start chart reviews for complication rates Review Didactic sessions available—lecture and online Organize didactic sessions/testing around didactic sessions Begin working on questionnaires Fourth quarter 2011 Start scheduling supervised scanning sessions Continue with chart reviews January 2012 Start testing physicians with direct observation of scanning and continue Start monthly questionnaires of ultrasound on wards for attendings and residents January 2013 End of surveys/daya analysis Next steps • What do you think • Credentialing • Billing and Coding