Psoriasis: The New
Skin
Paris Fears
Queens University of Charlotte
SPAEP I Pittsburgh, PA
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
Psoriasis
• ‘Psora’ means to itch in
Greek
• Gain an understanding of the
disease, Psoriasis
Questions
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Psoriasis
• Psoriasis, a chronic noninfectious immune-mediated
inflammatory skin condition that
causes thick red and flaky
patches of skin
• Natural Course
• 5 common types
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Psoriasis
• Psoriasis, a chronic noninfectious immune-mediated
imflammatory skin condition that
causes thick red and flaky
patches of skin
• Natural Course
• 5 common type
Plaque*-basic dry, itchy, red skin in common sites
Guttate- proceeds after strep throat; numerous red
scaly bumps
Inverse*- occurs in excess skin folds and soft tissue
Pustular- small pus filled bumps on whole body or
hands and feet
Erythrodermic- aggressive plaque with pain and wide
patches on entire body
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Psoriasis
• Mistoken for 150 years
• 1700’s to 1800’s Robert
Willian and Jacob Plenck
• 1841 Ferdinand von Hebra
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Psoriasis
• 7.5-8.5 million
• 125 million
• 150,000
• <400, >400
• Everyone is at risk
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
•40% increase in risk of contracting Psoriasis
with "familial tendency"
•Identical Twins incidence
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Psoriasis
• Psoriasis triggers
• Stress
• Little Sun Light
• Injury to skin
• Medication
• Immune system
deficiencies
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Psoriasis
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Psoriasis
Psoriasis
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
• $1.6 billion to $4.3 billion
dollars
• 75% believe in negative
impact
• Comorbidities
•
•
•
HIV
CVD
Obesity and Alcohol Abuse
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
Psoriasis
• Controlled not Cured
• Topical treatments
• Home remedies
• Pills
• Alternative treatments
Summary
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
•
•
•
•
•
Prevalent in all genders races, and
ages 3-95
Effects about 125 million people
worldwide
Complex auto-immune inflammatory
skin condition which includes, white
scaly and raised red lesions
Triggers include anything from
bacterial and viral infection to stress
The exact schematics to cure this
disease are still a mystery
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
QUESTIONS?
Table of Contents
Introduction
What is Psoriasis
Background
Epidemiology
Genetics
Physiology
Quality of Life
Treatments
Conclusion
Questions
References
References
• Babu, Hanish. "History of Psoriasis.” General Medicine
(suite 101) (2008): n. pag. Web. 17 Jul 2011.
http://www.suite101.com/content/history-of-psoriasis-a85546.
• Bhosle, Monali J, Amit Kulkarni, Steven R Feldman, and
Rajesh Balkrishnan. "Quality of life in patients with psoriasis."
Health and Quality of Life Outcomes 4.35 (2006): Web. 17 Jul
2011. http://www.hqlo.com/content/4/1/35>.
• Kurian, Anil, and Benjamin Barankin. "Current Effective
Topical Therapies in the Management of Psoriasis." Skin
Therapy Letter 16.1 (2011): 4-7. Web. 26 Jun
2011.http://www.skintherapyletter.com/2011/16.1/2.html.
• Schön, Michael P, and W.-Henning Boehncke. "Psoriasis."
N Engl J Med 352. (2005): n. pag. Web. 17 Jul 2011.
http://www.nejm.org/doi/full/10.1056/NEJMra041320#t=article.