Radical Laparoscopic Prostatectomy: Managing Localized Prostate Cancer Chase Wilson M1 S Patient Presentation S Difficulty urinating S Decreased force of urine flow S Blood in urine and/or semen S Swelling in legs S Pelvic pain Clinical Screening S Digital Rectal Exam (DRE) S Abnormal size/texture of prostate S PSA > 4.0 ng/mL Diagnostic Tools and Stages of Prostate Cancer S Ultrasound S Prostate biopsy (Gleason score) S CT Scan S MRI S Stage I—not detectable on DRE S Stage II—detectable on DRE, confined to prostate S Stage III—spread to seminal vesicles/nearby tissues S Stage IV—complete metastasis Non-Surgical Treatment Options S Radiation Therapy S External radiation S Brachytherapy (radioactive seeds) S Hormone therapy (decrease testosterone levels) S Medications S Orchiectomy S Chemotherapy Surgical Treatment Options S Retropubic Surgery S Perineal Surgery S Laparoscopic Surgery S Robotic Surgery Advantages of Laparoscopic Approach S Better visualization of prostate anatomy S Reduced blood loss S Better nerve sparing S Quicker post-operative recovery Laparoscopic Prostatecomy: Operating Room Layout Video monitors Assistants Surgeon Patient in 30° Trendelenburg Standard Laparoscopic Instruments S 0° Laparoscope S Fine dissecting scissors S Ultrasonic dissectors S Fine grasping forceps S Needle holder S Suction-irrigation device S Retrieval bag S Grasping urinary catheter S 2.0 braided suture, 26 mm needle S 3.0 absorbable, monofilament suture, 26 mm needle Trocar Placement A: Below umbilicus B: 2 cm medial to ASIS E: 2 cm medial to ASIS C: Between A & B D: Midline, between umbilicus and pubic symphysis Instrument Placement Laparoscope Grasper/s uction Forceps, grasper Grasper/suction, scissors Ultrasonic scissors, needle holder Prostatectomy Procedure 1 Detach bladder from anterior abdominal wall (D1_:12) 2 Anterior and lateral dissection of prostate (:16-40) 3 Divide prostate and bladder neck (D2_:02-08) 4 Dissection of ductus deferens and seminal vesicles (:12) 5 Incise Denovillier’s fascia, dissect prostate from rectum (:22) Prostatectomy Procedure 6 Carefully dissect neurovascular bundles from lateral prostate (:28) 7 Hemostasis and division of superficial dorsal vein (:46) 8 Divide prostate and urethra (:52) 9 Remove prostate, seminal vesicles, and ductus deferens (:57) 10 Vesicourethral anastomosis (D3) Detach Bladder Anterior abdominal wall Bladder Future Retzius’ space Anterior/Lateral Dissection Location of superficial dorsal vein Pelvic rim Prostate (Inside Retzius’s space) Superficial Dorsal Vein Superficial dorsal vein Pelvic rim Pelvic floor (levator ani and endopelvic fascia) Prostate Location of nerve bundle Divide Prostate and Bladder Neck Superior prostate Urinary catheter Bladder neck Seminal Vesicles/Ductus Deferens Seminal vesicle Location of neurovascular bundle Ductus deferens Denovillier’s Fascia Seminal vesicle Neurovascular bundle Posterior prostate Denovillier’s fascia Rectum (deep to denovillier’s fascia) Nerve Sparing Fine dissecting scissors Scissors dissect between prostatic capsule and lateral prostatic fascia Plexus of nerves Neurovascular bundle Division of Superficial Dorsal Vein Superficial dorsal vein Anterior prostate Division of Prostate and Urethra Urethra Catheter Prostate Prostate Removal Pelvic rim Lateral prostate Superior prostate Vesicourethral Anastomosis Urethra Catheter w/ grasper Anchor stitch Needle holder Bladder neck Time Lapse Anastomosis Urethra Bladder neck Post-Operative Care S Infection control: S Antibiotics S Drain S Urinary catheter (removed ~7 days post-op) S Blood thinners S Little pain medication necessary Operative Complications S Infection S Incontinence S Erectile dysfunction S Persistent cancer S Blood clots References S Images and Procedure: Dr. Strup’s Radical Laparoscopic Prostatectomy Teaching DVD S Background information: S Piechaud T, Saussine C. Laparoscopic radical prostatectomy: transperitoneal approach. Epublication: WeBSurg.com, Feb 2006; 6(2). URL: http://www.websurg.com/ref/doiot02en302.htm