The IOL= The IOL-VIP System

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Dominic McHugh

Royal Society of Medicine

2010

ARMD

 Leading cause of blindness (“SVL”) in the Western

World

 2.7 million in the UK have some loss.

 54% increase in >75s over the next 25 yrs.

ARMD

Quality of Life

With ARMD Without ARMD

Home Care 23%

Falls 16%

5%

8.3%

Falls With Fractures 3.5% 1.5%

Healthcare Costs €12,579 €1,300

(£8,521) (£885)

LVA Possibilities

Surgical Rehabilitation for ARMD

• Hanita Ben-Sira implant

Galileian telescope 2x

IOL+spectacle

• Intraocular Miniature Telescope

Galileian telescope 2.2- 3.5x intra (Lipshitz)

Difficulty maintaining coaxial alignment

Monovision

VF 20°

11 mm incision

IOL-VIP System

BCC IOL in the capsular bag = telescope ocular

BCX IOL in AC= telescope objective

IOL-VIP System

PC IOL AC IOL

-66D +55D

IOL CHARACTERISTICS

ANTERIOR CHAMBER IOL (BCX) PC IOL (BCC)

Optic

Optic

Material

Diameter

Thickness

PMMA with UV filter

5.0

1.5mm

Material

Diameter

Thickness

PMMA with UV filter

5.0

1.5mm

Haptics

Haptics

Loop shape

Material

Angle

Z

PMMA-1P

10°

Loop shape

Material

Angle

C

PMMA-1P

IOL power

IOL power +55.00 D

-66.00 D

Inclusion criteria for IOL-VIP surgery

• Bilateral stable macular degeneration/macular hole

• VA 6/18-6/60

• Adequate endothelial cell count

• Adequate AC depth

• Good peripheral field

• Predicted benefit by IOL-VIP simulator

Exclusion criteria for IOL-VIP Surgery

• Active exudative macular degeneration

• Glaucoma

• PAS

• Cornea guttata

• Endothelial cell count < 1600 cell/mm2

• Shallow anterior chamber with depth < 3 mm

• Corneal diameter < 11 mm

IOL-VIP

Proposed mechanism of action

Prismatic deviation of

Image to PRL.

Image magnificiation

~1.3

Image shift to PRL (MP)

Pre-op

Post-op

RE preop BCVA : 0.25

postop BCVA: 0.5

(Fasciani et al, 2008)

LE preop BCVA : 0.3

postop BCVA: 0.7

IOL-VIP Simulator Prism

IOL-VIP

Preoperative assessment

Best VA without and with simulator prism, rotated to achieve PRL

IOL-VIP System

Optimal simulator orientation determines relative IOL position

Right Eye Left Eye

12 12

9 3 9 3

12

9

6

6

3

12 6

9

6

3

9

9

8-7

IOL-VIP System

Optimal simulator orientation determines relative IOL position

Right Eye

Left Eye

12 12

1-2

1-2

3 9 3

8-7

6

1-2

6

1-2

12

3

8-7 8-7

6

• Corneal tunnel (superior/temporal depending on

IOL orientation

• Large (6-7 mm) CCC

• Phacoemulsification if phakic

• Enlarge corneal incision to 7 mm

• PC IOL: bag if phakic, sulcus if pseudophakic

• PI+miochol

• A/C IOL

• Corneal sutures

IOL-VIP

Surgery

IOL-VIP

Visual Outcome

Orzalesi et al

2007

IOL-VIP

Postoperative findings

• Low surgical complication rate

• Endothelial cell loss 7%

• PCO 18%

• High hyperopia in emmetropes; better if myopic

• Recent availability of “bespoke” implants

Advantages

• Improves reading/distance vision in suitable cases (6/18-

6/60 pre op; small-moderate central scotoma)

• Patients comment favourably on scotoma shifting away from centre

Disadvantages

• Careful selection required: pathology; psychology; costs

• Lengthy (6 week) postoperative rehabilitation training

• Suture removal

• Refractive error : hyperopia and astigmatism (reduced with new implants

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