If the thymus failed to produce thymic
hormones, which population of lymphocytes
would be affected?
a. B lymphocytes
b. T lymphocytes
c. monocytes
d. antigen-producing cells
© 2012 Pearson Education, Inc.
Which of the following is true of lymphatic
a. They have smaller diameters than blood
b. Endothelial cells of lymphatic capillaries
are not bound tightly together, but they do
c. They have thicker walls than blood
d. They form continuous tubes.
© 2012 Pearson Education, Inc.
All of the following EXCEPT _________ is a
function of the lymphatic system.
a. producing, maintaining, and distributing
b. resisting and overcoming disease
c. draining lymph from the bone marrow
d. maintaining normal blood composition
and volume
© 2012 Pearson Education, Inc.
Why do lymph nodes enlarge during some
a. because of bacterial invasion and
b. due to accumulation of antibodies
c. due to accumulation of circulating T cells
d. due to phagocytic and lymphatic cell
© 2012 Pearson Education, Inc.
Which of the following is a dangerous
consequence of lymphedema in a limb?
a. accumulation of toxins and pathogens
due to stagnant interstitial fluids
b. swelling and distension of the limb
c. loss of elasticity in connective tissue of
the affected limb
d. all of the above
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What effects do pyrogens have in the body?
a. release complement
b. increase temperature/cause fever
c. stimulate NK cells
d. release interferon
© 2012 Pearson Education, Inc.
Which of the following is NOT a characteristic
or function of nonspecific defenses?
a. are present at birth
b. destruction of abnormal cells by NK cells
c. dependence on the activity of
d. interferons coordinating defenses against
viral infections
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How do interferons increase resistance to
viral infections?
a. They can respond immediately.
b. They recognize abnormal cells by the
presence of unusual antigens.
c. They interfere with viral replication inside
d. All of the above are correct.
© 2012 Pearson Education, Inc.
Why would the liver, lungs, and CNS be
affected by a low monocyte count in blood?
a. Kupffer cells, alveolar macrophages, and
microglia are derived from monocytes.
b. Lack of monocytes causes NK
lymphocytes to attack those structures.
c. The liver, lungs, and CNS are secondary
parts of the immune system.
d. None of the above is correct.
© 2012 Pearson Education, Inc.
All of the following EXCEPT ________ is an
effect of complement activation.
a. making target cells easier to engulf
b. destruction of target cell membranes
c. attracting neutrophils and macrophages
d. reducing inflammation
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A decrease in the number of cytotoxic T cells
directly affects which type of immunity?
a. acquired immunity
b. innate immunity
c. humoral immunity
d. cell-mediated immunity
© 2012 Pearson Education, Inc.
The spleen is _____.
a. a fragile organ that can rupture easily
b. the site where red blood cells are recycled
c. the site where B and T cells can respond
to antigens in circulating blood
d. all of the above
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Which of the following correctly describes the
sequence of WBCs responsible for
overcoming an infection?
a. neutrophils and NK cells →
phagocytes/cytotoxic T cells → plasma
b. memory B cells → plasma cells → NK
c. phagocytes → plasma cells → antibodies
d. B cells → helper T cells → phagocytes →
CD8 cells
© 2012 Pearson Education, Inc.
How is the secondary response affected if
memory B cells for a particular antigen are
a. A pathogen that had previously invaded
would be recognized and quickly killed.
b. The secondary response would not occur.
c. Memory T cells take over the role of the
memory B cells.
d. CD4 cells would differentiate into B cells.
© 2012 Pearson Education, Inc.
How does the absence of helper T cells affect
the antibody-mediated immune response?
a. Neither B cells nor T cells are stimulated to
respond to a pathogen; therefore, no
immune response occurs.
b. Cytotoxic T cells proliferate.
c. Class II MHC proteins appear in the cell
d. Immune response is unaffected by loss of
helper T cells.
© 2012 Pearson Education, Inc.
Which of the following conditions can be
determined with a skin test?
a. if a baby has severe combined
immunodeficiency disease
b. if a person has been exposed to an
c. if a person has an autoimmune disease
d. if a person has diabetes mellitus
© 2012 Pearson Education, Inc.
Which kind of immunity protects a developing
fetus, and how is that immunity produced?
a. natural active immunity; maternal illness
and recovery
b. natural passive immunity; the transfer of
IgG antibodies from the mother to the fetus
through the placenta
c. artificial passive immunity; injections of
gamma globulins
d. artificial active immunity; vaccinations
© 2012 Pearson Education, Inc.
The formation of an antigen–antibody complex
may cause elimination of the antigen in what
a. The antibody binds to a site on a virus
making the toxin incapable of attaching itself
to a cell.
b. An antibody binds to antigenic determinant
sites on two different antigens.
c. Antigens covered with antibodies attract
d. All of the above are correct.
© 2012 Pearson Education, Inc.
Artificially acquired passive immunity _______,
while artificially acquired active immunity _______.
a. is genetically determined; is conferred by
administration of antibodies
b. is conferred from mother to infant through
breast milk; develops after exposure to
antigens in the environment
c. is conferred by administration of antibodies;
develops after administration of an antigen to
prevent disease
d. stimulates antibodies against something you
might encounter in the future; combats
© 2012 Pearson Education, Inc.
Which analogy is most appropriate for
comparing the interaction of an antibody’s
active site binding with an antigen?
a. the heavy-chain constant segment’s
interaction with the light chain of an
b. a drug reaction, such as penicillin allergy
c. an enzyme interacting with a substrate
d. the binding of a hapten and carrier
© 2012 Pearson Education, Inc.
A tumor cell has developed and begun to
divide in Amy’s liver. What type of immune
cells will be able to detect and kill the tumor
a. macrophages
b. basophils
c. natural killer cells
d. B cells
© 2012 Pearson Education, Inc.
David suffers from rheumatoid arthritis. What
is the term for this type of immune disorder?
a. autoimmune disease
b. allergy
c. immunodeficiency
d. lymphedema
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What are the best medications to use for
tissue rejection in organ transplants?
a. interferon because it will diminish viral
b. cyclosporin A because it will decrease
helper T cells
c. prednisone because it will decrease both
inflammation and immunity
d. monoclonal antibodies because they are
not going to be recognized by T cells
© 2012 Pearson Education, Inc.
How can the presence of an abnormal peptide
in the cytoplasm of a cell initiate an immune
a. by stimulating production of pyrogens,
beginning an immune response
b. by becoming attached to B cells, which
launch an immune response
c. by becoming attached to MHC and being
presented to T cells
d. by altering the genetic programming of
the infected cell
© 2012 Pearson Education, Inc.
Denise is allergic to pollen. What is an allergy
and how is allergy to pollen classified?
a. results from treatment with
immunosuppressive agents; delayed
b. develops when the immune response
targets normal body cells; cytotoxic reaction
c. an inappropriate or exaggerated immune
response; immediate hypersensitivity
d. results from problems of development of
lymphoid organs; immune complex disorder
© 2012 Pearson Education, Inc.
Why is having both cell-mediated and antibodymediated immunity integral to a healthy immune
a. T cells defend against pathogens inside cells,
while B cells defend against antigens in body
b. Cell-mediated immunity in genetically
determined, while antibody-mediated
immunity is acquired.
c. Cell-mediated immunity is “specific,” while
antibody-mediated immunity is “nonspecific.”
d. None of the above is correct.
© 2012 Pearson Education, Inc.
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