Training for Inactivated Poliovirus Vaccine (IPV)
introduction
Module 3
Inactivated poliovirus vaccine
eligibility
Learning objectives
 At the end of the module, the participant will be able to:
– Describe the recommended immunization schedule for inactivated
poliovirus vaccine (IPV)
– Determine when an infant is and is not eligible to receive IPV
– Describe ways to determine a child's eligibility for IPV when a
written record is unavailable
– Describe the absolute contraindications for vaccination
 Duration
– 30 minutes
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
Key issues
1
What is the recommended schedule
for IPV?
2
What do you do when the exact date
of birth (DOB) or the immunization
card is missing?
3
What are the contraindications to
vaccination?
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
At what age should IPV be administered?
 Give IPV at or after age 14 weeks, usually with OPV3 and
DTP3/Penta3
 IPV should be given in addition to OPV
 OPV is still the primary vaccine to achieve eradication
Vaccine
• Example EPI schedule using
DTP-Hib-Hep B (Pentavalent),
pneumococcal conjugate (PCV)
and rotavirus vaccines
• IPV should be given at 14
weeks, or at the first contact
after 14 weeks
Birth
6 wks
10 wks
BCG
Pentavalent
PCV
Rotavirus*
OPV
IPV
*rotavirus vaccine may be 2 or 3 doses, depending upon the vaccine used
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
14 wks
What should you do in this scenario?
A child's immunization card
shows that he/she is now 18
weeks old and has only
received BCG and 2 doses of
OPV.
What should you do?
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
What should you do in this scenario?
A child's immunization card
shows that he/she is now 10
weeks old and has only
received BCG and one dose
of OPV.
What should you do?
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
What should you do in this scenario?
A child comes in at 6 months
of age and has had no
vaccines.
What should you do?
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
What should you do in this scenario?
A caretaker brings a child to the
health center for the first time
and comes without any written
documentation.
The caretaker does not
remember the exact date of
birth (DOB) of the infant.
What are some possible ways of
determining the child’s DOB?
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
Possible ways to estimate the DOB
 See if the caretaker can recall when the child was born
relative to a cultural, religious, national or local event
 Look for DOB record in other documents kept in the health
center or other local registries
– Antenatal care record
– Birth registry
 Look for development indicators
– A child who can sit unsupported and reach out with one hand is
probably old enough to get IPV and other required vaccines
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
Absolute contraindications to IPV
Do not
vaccinate if
recipient has:
• Known or documented allergy to vaccine components,
including:
- Streptomycin
- Neomycin
- Polymyxin B
• History of an allergic reaction following a previous IPV injection
• Thrombocytopenia (insufficient blood platelets, which play an
important role in coagulation)
• Other bleeding disorder
Wait!
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Postpone
vaccination if
recipient is:
• Taking temporary treatment that suppresses the immune
response
- Treatment could reduce immune response to the vaccine
- Postpone vaccination until the end of the treatment to
make sure the infant is well protected by the vaccine
Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
Can IPV be administered on schedule to
immunodeficient infants or infants born prematurely?
 Yes!
 Immunodeficiency does not prevent
administration of IPV
 Vaccination of infants with immunodeficiency,
such as HIV infection, is recommended
 Infants born prematurely should receive IPV
on schedule (at or after 14 weeks of age)
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
Contraindication Checklist
Do I still give IPV if recipient has….?
… mild illness
… malnutrition
… HIV
… prematurity
… allergy to streptomycin, neomycin or
polymyxin B
… bleeding disorder
… had a previous reaction to IPV
… taking treatment that suppresses
immune response
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015
Yes
No
Postpone
Key messages
 First IPV dose should be given at 14 weeks of age or at first
contact after 14 weeks
 IPV can be given and the same time as other injectable
vaccines like pentavalent and pneumococcal vaccine
 If EPI schedule currently includes OPV, do not replace OPV
with IPV; the dose of IPV should be added to the schedule
 IPV can be administered to children with immunodeficiency
disorders and those born prematurely
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End of module
Thank you for your
attention!
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Inactivated poliovirus vaccine eligibility, Module 3 | 13 February 2015