The Challenges of the Internet of Nano Things Sasitharan Balasubramaniam (Sasi) (sasi.bala@tut.fi) Nano Communication Centre Department of Electronics and Communications Engineering Tampere University of Technology Department of Communications Engineering Outline • Nanotechnology • Nanomachines • Nano Communications • Molecular Communications • Internet of Nano Things (IoNT) • Applications of IoNT • Plans for Horizon2020 Department of Communications Engineering Nanotechnology • Concept was first proposed by Richard Feyman in 1959 in his nobel prize acceptance speech • “Plenty of room at the bottom” • Nanotechnology are devices on the scale of the order of one billionth of a meter(10-9) • Example materials: Graphene, Nanocrystallites, Nanoparticles • Numerous healthcare applications • Improved monitoring of chronic diseases • Accurate drug delivery • Nanorobots that can perform surgery • Other applications include Aeronautics, Environmental Science Department of Communications Engineering Nanomachine to treat cancer • Issue with current chemotherapy is that drugs kill good cells • Aim – deliver drug to targeted areas • Cut the dosage down by hundred – thousand times • Developed at the University of California, Los Angeles (UCLA) • Honeycomb nanostructure that holds the drug particles • Valves releases particles. Numerous approaches: • • Chemical agent Light http://www.rsc.org Department of Communications Engineering DNA Nanorobot • Developed at Wyss Institute • Robotic device developed from DNA • DNA origami – 3D shapes created from folding DNA • Two halves connected with a hinge, and shut using DNA latches • The latches can be designed to recognize certain cell proteins and disease markers • Hold molecules with encoded instructions (antibody fragments) • Used on two types of cancer cells (leukemia and lymphoma) http://wyss.harvard.edu Department of Communications Engineering Problems and Challenges • Scale of nanodevices allows us to…. • Reach hard to access areas….. • Access vital information at a whole new level (molecular information)….. • Devices of the future will be built from nanomaterials • Limitation – limited functionalities!! • Communication and networking between nanomachines would further advance their capabilities and functionalities Department of Communications Engineering What is the answer…..??? Department of Communications Engineering Nano Communications! • Two broad Areas………… o Electromagnetic (EM) Nano Communications o Molecular Communications Department of Communications Engineering Molecular Communication Nanomachine Bacteria I. F. Akyildiz, F. Brunetti, C. Blasquez, “Nanonetworks: A New Communication Paradigm”, Computer Networks, 52, 2008 • Sender nanomachines encode information into information molecules (e.g. DNA, proteins, peptides) • Information can be transmitted through diffusion or active transport • Ability to create communication systems and networks using biological components and processes that are found in nature • Interdisciplinary research (nanotechnology, communication technology, biochemistry, molecular biology) Department of Communications Engineering Diffusion-based Molecular Communications • Communication is performed through diffusion of molecules • Information is embedded into the molecules • Ideally this is suited to fluidic medium I. F. Akyildiz, J.M. Jornet, M. Pierobon,,"Nanonetworks: A New Frontier in Communications," Communications of the ACM, vol. 54, no. 11, pp. 84-89, November 2011. Department of Communications Engineering Bacteria Communication Nanonetworks (1) Bacteria can hold genetic information (plasmids) Mess. 2 Mess. 1 Bacteria can swim – possible attraction through the process of chemotaxis M. Eisenbach, “Bacterial Chemotaxis”, Encyclopedia of Life Sciences, 2001 λRandom A Chemoattractant B 20μm λBiased L. C. Cobo-Rus, I. F. Akyildiz, "Bacteria-based Communication in Nanonetworks", Nano Communication Networks, vol. 1, no. 4, pp. 244-256, December 2010. Department of Communications Engineering DTN Bacteria Nanonetworks Opportunistic multi-hop routing in bacteria nanonetworks using chemotaxis and conjugation. Each Bacteria is akin to a mobile node. Chemoattractant 3 Emitter 3 Chemoattractant 3 Bacteria with transferred message Bacteria conjugation point 2 2 Relay Node 2 1 (a) 1 (b) 1 (c) Sasitharan Balasubramaniam, Pietro Lio’, Multi-hop Conjugation based Bacteria Nanonetworks, IEEE Transactions on NanoBioscience, vol. 12, no. 1, March 2013. Department of Communications Engineering Smart Organ • Through tissue engineering we can develop various body parts • Tissues -> Organs (skin, bone) • Using nanomaterial scaffolds, we can grow cells on the scaffold into tissue • Utilizing 3D bioprinting to develop organs • Challenge – integration to the existing system within the body • Integrate sensors into the tissue (Smart tissue) • www.mhs.manchester.ac.uk Robert Langer (BBC, October 2013) www.explainingthefuture.com Department of Communications Engineering Internet of Things Environmental Sensors BAN • Physical Interconnection of devices, objects……integrated with virtual interconnection of services • A large number of these devices are MINITIARIZED devices (sensors, BAN)!!! Department of Communications Engineering Internet of NANO Things Environmental Sensors BAN • MORE MINITIARIZED -> Interconnection of devices at Nanoscale AND connection to the wider Internet Department of Communications Engineering IoNT Architecture Services Layer Context Management layer nanosensors nanosensors on clothing s Sweat Micro-gateway Query routing Phone surface sensors – nanosensors nanosensors Microgateway Blood Molecular nanonetworks Department of Communications Engineering Pathogens EM – nano communicatio n Nano-sensors For environmental monitoring Chemicals Allergens IoNT Challenges: Context Models Raw Data Nano Sensors Micro Sensors Molecular Communication Temperature Pressure Data Collection Services Application Services Micro- Context Inference and Deduction Context Model Contains Context Broker Bio medical Gene Ontology Smart Office Ontology Nano Sensors Contains User Profile PerformingAt EM nano Shopping Env. Smart Home Nano-sensor Bacteria Nanonets Calcium Signaling Activity Context Processing BAN2 Accelerometer MicroContex t Contex t BAN Contains LocatedAT Location X-value Y-value Z-value Service Directory Medical Condition Contains Device Contains Nano Sensors Bio nano-sensor Cross domain ontologies Ontologies and Knowledge base (a) Cross domains of heterogeneous knowledge bases Department of Communications Engineering (b) Mobile Phone IoNT Challenges: Service Models Application Services A MicroContext ServiceComposition”Molecular Nets” MicroContext ServiceComposition”EM Nanonets” ContextInteraction Data Collection Services A2 ContextInteraction MicroContext Data Collection Services A1 EM Nanonets Department of Communications Engineering Molecular Communications • Multitude of nanodevices and micro-gateways • Big data from nanoscale sensors and networks • New distributed service models (lightweight services) Applications (1): Body Area NanoNetworks (BAN2) • New healthcare monitoring approaches • BAN -> BAN2 • Heterogeneous molecular communication networks • Short range (Calcium signalling) • Medium range (Bacteria) • Long range (Hormones) Nucleus Cell Message biomolecule Long range transmis sion Nucleus Enzyme protocols Cell Nucleus Cell Microgateway Nucleus Cell Nucleus Short range transmissio n Synthetic Nanosensor Cell Nucleus Cell Baris Atakan, Ozgur B. Akan, Sasitharan Balasubramaniam, Body Area NanoNetworks with Molecular Communications in Nanomedicine, IEEE Communications Magazine, January 2012. Department of Communications Engineering Applications (2): Smart Cities Smart Agriculture • Contamination control • Urban agriculture (hydroponics) Smart Transport • Pollution control Department of Communications Engineering Smart Water • Contamination control • Infrastructure monitoring (smart pipes) Smart Energy • Monitoring of renewable energy infrastructure ( graphene-based solar panels) • Monitoring of biofuel production EU FET Project Plan (1) • Coordinated Support Action (FET OPEN2 - September 2014) Planned submission September 2014 (7 partners including TSSG - WIT, Ireland (coordinator); Koc, Turkey, TUT (Finland)........ • FET Open (FET OPEN1 - September 2014): Internet of Bacteria Things • Collaborator: Prof. Ozgur B. Akan, Koc University • Partners: University of Helsinki (Finland), Tampere University of Technology (Finland), Koc University (Turkey), University of Cambridge (UK), Tyndall Institute (Ireland) • Objective: To realize a simple bacteria nanonetwork that interfaces to the Internet (software services) • • Bridge ICT to Molecular Biology World. Linking communication of behaviour of bacteria to the software services in Telecommunications. Bacteria communication will be conducted through wet lab experiments (Univ. of Helsinki). Department of Communications Engineering EU FET Project Plan (2) Services Services Services Bacteria Microgateway Department of Communications Engineering Conclusion • Basics of Nanotechnology • Examples of Nanomachines • Nano Communication • • Electro-magnetic Nano Communications Molecular Communications • Internet of Nano Things • • Body Area Nanonetworks Smart Cities Applications • Plans for Horizon2020 Department of Communications Engineering