Arduino-Based Patient Simulator Patient Simulator Rea Rostosky, Tyler Ishita Jain Rea R.,Matt MattVenard, V., Tyler B.,Brann, Ishita J. Mentors: Mr. Tommy Roussel & Dr. Darren Brey What is a Patient Simulator? Patient Generated Physiological Signal with Known Characteristics Patient Simulator Patient Monitor http://www.healthcare.philips.com http://www.flukebiomedical.com Current Patient Simulators Expensive Pronk® SL-8 SimSlim® $1495 Fluke ProSim 8 $1014 http://www.pronktech.com http://www.flukebiomedical.com Limited Functionality HE Instruments $240 Currently used in UofL Bioinstrumentation Lab! http://www.heinstruments.com/ Design Importance / Benefits • • • • High Functionality for Low Cost o Who doesn't want that? Arduino Platform o Open source Standalone/Portable Mass producible o Mostly off the shelf parts http://designbuddy.com/how-toavoid-cheap-logo-design http://arduino.cc/ Intended Users Users Purpose Served by Device Bioinstrumentation Students physiological signal generation Device testing of device prototypes Developers/Researchers Medical Technicians calibration in hospital settings Medical Professionals in Developing Nations calibration in rural settings Design Criteria • • • • • • < $50 EKG, Blood Pressure, Respiration, & Temperature Signals Handheld Standalone (Battery Powered) Simple User Interface Compatible with Various Patient Monitors Design Timeline V.1 V.4 V.3 V.2 DAQ http://www.gettyicons.com http://www.arduino.cc 2nd Order RC Filter Coding • • • Adapted code to disable built-in interrupt in PWM digital signal Converting to hexadecimal and acquiring appropriate sample rate Incorporating user interface o LCD and push buttons http://www.hdwallpapersdepot.com Design Solution http://www.cooking-hacks.com http://www.sainsmart.com http://www.alkalinebatteries.us http://www.usbgeek.com Available Signals 1. Normal EKG 2. Bradycardia 3. Tachycardia 4. Ventricular Bigeminy 5. Slow Alternating Ventricular Bigeminy 6. Rapid Alternating Ventricular Bigeminy 7. Bidirectional Systoles 8. Arterial Blood Pressure 9. Normal Resting Respiration 10.Obstructed Respiration 11.Hypoventilation 12.Temperature (37oC) Testing Data • Verification o • o Filter must have a cut-off of 7.0 +/- 0.5 kHz (76.9 +/- 6.2 dB) Approx. 5x larger than highest frequency we output Difficulty in validation http://statistically-funny.blogspot.com Benefits of This Design Market Patient Simulators Needed Notes Biomedical Engineering Programs 3500 514 programs nationwide totaling approximately 9800 students Biotech Engineering Programs 2500 181 programs nationwide totaling approximately 6900 students Developing Nations (via DWB) 1000 22,000 doctors, nurses, logisticians, and other medical staff serving and treating over 8,500,000 patients in 67 countries Future Device Improvements • Power o • • • o On/Off Switch Casing (Battery Access) Scroll o ...delay Digital Pin 6 EKG Leads o The more the merrier Clipart by 3poD http://clipartof.com/16379 Future Device Direction Projected Growth by 2014 Market Simulators Needed Income (at $125 Manufacturing Total Revenue per simulator) Cost (at $35 per simulator) Biomedical Engineering Programs 5200 $650,000 $182,000 $468,000 Biotech Engineering Programs 3700 $462,500 $129,500 $333,000 Developing Nations (via DWB) 1250 $156,250 $43,750 $112,500 Total 10150 $1,268,750 $355,250 $913,500 http://www.theiia.org/intAuditor/m edia/images/forward.png Conclusions • Functional Arduino-Based Patient Simulator 12 available signals o LCD/button user interface o Versatile banana clip outputs o Standalone, Powered by 9 volt alkaline battery o • Total Component Cost of Final Simulator: ~$35 Lessons Learned • • • • • • Breadboarding PCB & Casing Fabrication Arduino Coding Improved Oscilloscope Proficiency Project Management Troubleshooting ....and how to make PIE! Acknowledgements University of Louisville, Department of Bioengineering • • • • • Mentors - Mr. Tommy Roussel, Dr. Darren Brey, and Dr. Andre Gobin Preliminary PCB Design - Dr. Martin O'Toole PCB Fabrication - Doug Jackson Acrylic Casing Fabrication - Scott Cambron Ordering Components - Connie York https://louisville.edu/spee d/bioengineering/faculty/s mallervitruveanguysmallc opy.gif/image_mini