Chapter 7 Mood Disorders © 2006, Prentice Hall, Wicks-Nelson History Psychoanalytic View Masked Depression Transient episodes due to development © 2006, Prentice Hall, Wicks-Nelson Mood Disorders Major Depressive Disorder (MDD) Depressed or irritable mood Loss of interest or pleasure Weight changes Sleep problems Motor agitation or retardation Loss of energy Feeling worthless or guilty Poor concentration Thoughts of death or suicide Need five symptoms for 2 weeks Problems must cause impairment © 2006, Prentice Hall, Wicks-Nelson Mood Disorders Dysthymic Disorder Depression less severe, but more chronic Depressed or irritable mood Appetite disturbance Sleep disturbance Low energy Low self esteem Poor concentration Hopelessness Symptoms last for a year or more Double depression is a term used when the child has both MDD and dysthymia Dysthymia usually begins before MDD © 2006, Prentice Hall, Wicks-Nelson Mood Disorders Adjustment Disorder with Depressed Mood Child has depressive symptoms in response to a clear stressor (e.g., move, divorce) Bipolar Disorder Mania Elevated or irritable mood Inflated self esteem High activity Rapid speech and thinking Distractibility Exaggerated well being and confidence Hypomania-milder form of mania © 2006, Prentice Hall, Wicks-Nelson Mood Disorders Bipolar Disorder Bipolar I –person has periods of mania and depression (manic depression) Bipolar II-person has periods of hypomania and depression Cyclothymia-chronic but mild fluctuations in mood that do not meet the criteria for mania or depression May be hard to diagnose in children © 2006, Prentice Hall, Wicks-Nelson Epidemiology MDD the most common type 80% of kids with depression have MDD 10% have double depression 10% dysthymia May be underestimated Episodes common in adolescence Gender differences do not occur until age 13 when girls report depression more often © 2006, Prentice Hall, Wicks-Nelson Epidemiology MDD Lower SES associated with higher rates Ethnic differences may exist when the effects of age or gender are examined 40-70% have another disorder © 2006, Prentice Hall, Wicks-Nelson Epidemiology Bipolar Rare in children (1%) Peak onset between 15-19 Males and females equally represented Co-occur with ADHD, ODD, substance dependence © 2006, Prentice Hall, Wicks-Nelson Course Depression Infancy Preschool Lethargy Feeding problem Sleep problem Irritability Sad expression Crying Failure to thrive Associated with maternal depression Irritability Sad facial expression Mood changes Feeding and sleep problems Lethargy Crying Hard to assess © 2006, Prentice Hall, Wicks-Nelson Course Depression Middle childhood Begin to report hopelessness and self deprecation around age 9-12 Adolescent Begins to look more like adult depression Median duration was 8 weeks Clinic samples have longer episodes Earlier onset correlated with longer episodes 70% have recurrent episodes (Kovacs, 1996) May be differences between prepubertal and postpubertal depression © 2006, Prentice Hall, Wicks-Nelson Course Bipolar Median duration of manic episode 10.8 months For children with the disorder, onset is earlier than those with MDD Non remitting symptoms and relapse not uncommon © 2006, Prentice Hall, Wicks-Nelson Etiology Biological influences Heritability 80% for bipolar disorders Onset of depression before age 20 associated with family history For depression genetic effects may be indirect Neurochemistry Norepinephrine Serotonin Acetylcholine Neuroendocrine system dysregulation © 2006, Prentice Hall, Wicks-Nelson Etiology Social Psychological Influences Separation and Loss Cognitive Behavioral/Interpersonal Interpersonal Learned Helplessness Attributions Beck’s Theory © 2006, Prentice Hall, Wicks-Nelson Etiology Parental Depression Increased risk of depression for children of depressed parents (including infants) Increased risk of other disorders Less likely to receive treatment Parental depression may cause the parent to withdraw, offer poor supervision, irritable, engage in frequent conflict Can effect attachment © 2006, Prentice Hall, Wicks-Nelson Etiology Peer Relations Rejected boys and girls and neglected girls are more likely to be depressed Cause and effect cannot be determined Children may feel or be less competent or have negative views of peers © 2006, Prentice Hall, Wicks-Nelson Suicide 3rd leading cause of death in 10-19 age group Rate highest for white males Rates for black males age 10-14 have increased slightly since 1995 Native American males have the highest rate proportionally Increased use of guns Females have higher rates of ideation and attempts than males High rate of reattempt Teens report problems coping; desire to escape © 2006, Prentice Hall, Wicks-Nelson Suicide Risk Factors Hopelessness Comorbid disorders Conduct disorder Substance abuse Prior attempts Poor interpersonal problem solving Family history of suicide Abuse Low parental monitoring High stress Media reports of suicide Neurotransmitter dysfunction © 2006, Prentice Hall, Wicks-Nelson Assessment Interviews Rating Scales Structured Clinical CBCL CDI RCDS Low levels of correlation between child and parent measures Peer nominations Assessment of cognitions and attributions Observations © 2006, Prentice Hall, Wicks-Nelson Treatment Pharmacological Antidepressant medication use controversial TCAs SSRIs Side effects Lack of research Recent controversy over link of SSRIs to suicide in youth © 2006, Prentice Hall, Wicks-Nelson Treatment Cognitive Behavioral Treatments Challenge cognitions and attributions Increase pleasurable experiences Enhance social skills Improve communication and conflict resolution Manualized treatment has support, particularly with teens. © 2006, Prentice Hall, Wicks-Nelson Treatment Research comparing methods has found that Cognitive Behavioral Therapy (CBT) very effective Most programs are not long enough Lingering symptoms Relapse in long term Interpersonal Psychotherapy (IPT) Treat grief, interpersonal disputes, role transitions, interpersonal deficits © 2006, Prentice Hall, Wicks-Nelson Treatment Bipolar May need hospitalization Mood stabilizing drugs such as Lithium SSRIs Education about disorder for family and patient Cognitive behavioral and psychosocial interventions Educational interventions © 2006, Prentice Hall, Wicks-Nelson handouts One illustrates the multiple influences in the dev of depression, the biol, the env, the family, life stress, and the effect on the child in terms of cognition and interpersonal skills The second points out that more recent studies of the effectiveness of therapy for depression show a modest effect, not a strong one, and that behavioural activation may be more important than cognitive therapy © 2006, Prentice Hall, Wicks-Nelson text It starts out by pointing out the controversies about a diagnostic category being a distinct entity The empirical approach does not really separate depression from anxiety, seeing them as part of one continuum, for example Remember that the empirical approach emphasized dimensions, not categories © 2006, Prentice Hall, Wicks-Nelson etc For example, is the diagnostic category of mania separate and valid, or is mania simply a sign of any of a number of severe disorders In terms of influences, there are distal and proximal ones, e.g., SES influences depression indirectly through its effects on the family, which has its caregiving and supervisory functions affected © 2006, Prentice Hall, Wicks-Nelson etc Another example about dimensions, the book mentions a continuum or spectrum of disorders related to mania, from simpler traits to more severe disorders, and with subsyndromal levels in between About distal and proximal, in terms of biol and genes, they do not cause depression directly, but lead to poorer social skills, thinking capacity, through effects on the child and family, and then the school experience and peers © 2006, Prentice Hall, Wicks-Nelson