A Pan-African Survey of ECT and establishing a Practitioners’ Network Dr Johan Leuvennink Consultant Psychiatrist SMMHEP 2nd Malawi Mental Health Research and Practice Development Conference Blantyre, Malawi March 2012 Declaration of interest • The speaker has no pecuniary interest in promoting the use of ECT • The speaker has received funding for teaching in ECT in an African setting from the Scottish Government under SMMHEP • The speaker has received research, advisory boards membership and speaker funding from pharmaceutical companies not in relation to ECT. • The speaker has not received funding for this survey. ECT: it's place in modern psychiatric practice • ECT trend in UK • Severe / Rx resistant major depressive episodes ECT: it's place in modern African psychiatric practice • Severe / Rx resistant major depressive episodes • Difference from UK practice: – Indications • Mania, acute schizophrenia, NMS – Treatment thresholds • in resource constrained areas (bed occupancy, available antipsychotic preparations IM, Oral, staff constraints) – Severity of psychopathology at time of presentation • Limited community psychiatry and early intervention opportunities Challenges in providing a modern, safe, evidence based ECT Service • Human resources: psychiatrists/ clinical officers/ specialist nurses/ anaesthetic staff • Equipment: – Availability, familiarity, maintenance – ECT machine, anaesthetic equipment, including machine,oxygen/O2 saturator, suction machines, emergency medicines & equipment, monitoring equipment. • • • • Isolation and deskilling Locality appropriate treatment and safety protocols Training opportunities Opportunities for collaborative research and audit Experience of ECT Clinical Networks elsewhere: • • • • SEAN ECTAS European ECT Network Setting up a Southern African Network for ECT (SANECT) SANECT February 2011 to date: • • • • First annual meeting (inaugural) Membership Links with other Networks Discussion forum – HIV and ECT – Serum glucose and ECT – Metal plate in skull • Pan-African Survey of ECT Purpose of Study • • • • Commonly prescribed treatment Similarities in challenges throughout Africa Scoping survey Baseline for further collaboration What this is not…. • Comprehensive survey of services • Ranking of service excellence Subjects and settings • Psychiatrists throughout Africa • Private Practice, District General Hospital and Teaching Hospitals Methodology • • • • • Subject identification Questionnaire sent as email attachment Questionnaire resent after 2 months Data analysed Anonymity protected in presentation/publication as regards Country of practice, Practitioners’ names and contact details. • Total questionnaires sent: 54 • Total respondents: 19 • Geographical spread: 12 countries • Practice type distribution: wide Survey Questionnaire Your name: …………………………………………………………………………………………………………… Your country of practice: …………………………………………………………………………………………………………… Is this a Private Practice? Yes / No Is this a teaching/academic hospital practice? Yes / No Is this a non-teaching hospital practice? Yes / No Your contact email address: ……………………………………………….. Please use this Word document to complete the questionnaire. Merely delete the wrong answer “Yes” or “No”. Then save the document (e.g. on your desktop) and send it back by attaching it to the return email to this address: JLeuvennink@nhs.net General: Do you practice or prescribe ECT in your service? Yes / No (If above answer is “No”, please still return the questionnaire and only answer the following 2 questions.) Do you consider ECT to be a controversial treatment in psychiatry? Yes / No Do you consider ECT an essential treatment in psychiatry? Yes / No Prescription: How many patients are on average given ECT per week in your service? What are the indications for your prescription of ECT? Severe depression Mild to moderate, but treatment resistant depression Mania Acute schizophrenia OCD Yes / No Yes / No Yes / No Yes / No Other (Please specify) ………………………………………………………………………. Is maintenance ECT given in your service? Yes / No Practice: Are patients given ECT in a dedicated ECT suite/treatment room/theatre? Yes / No Do you use modified ECT? (with anaesthetic and muscle relaxant) Yes / No Do you monitor seizure activity with EEG monitoring? Yes / No Do you use bilateral and unilateral ECT application? Yes / No Do you titrate the dose of electricity given or are patients given a fixed dose? Dose titrated according to seizure threshold ………………..Yes / No Fixed dose given according to certain guidelines ………….Yes / No Is the dose of electricity altered according to seizure length/side effects/clinical response? According to seizure length Yes / No According to side effects Yes / No According to clinical response/non-response Yes / No Is a suction machine available in the treatment room? Yes / No Are patients monitored by a. ECG? Yes / No b. pulse oxymetry? Yes / No c. BP? Yes / No d. end-tidal CO2? Yes / No Is an emergency drug trolley/box available in the treatment room? Yes / No Is resuscitation equipment available in the treatment room? Yes / No Monitoring: Are patients routinely assessed for treatment emergent physical side effects? Yes / No Are patients routinely assessed for treatment emergent cognitive impairment? Yes / No If above answer “Yes”, how is this done? …………………………………………… …………………………………………………………………………………………………………………… …………. …………………………………………………………………………………………………………………… …………. How long is treatment continued for? ……………………………………………………………………….. …………………………………………………………………………………………………………………… …………. Staff training and experience: Do you consider staff prescribing and delivering ECT in your service to be adequately trained and updated in this treatment? Yes / No Results Responders' Practice Settings 100% 90% 80% 9 9 10 70% 60% Series2 Series1 50% 40% 30% 10 10 9 20% 10% 0% Private Practice Teaching Non-teaching General attitude to ECT 100% 1 2 90% 80% 9 70% 60% 50% 18 17 Series2 Series1 40% 30% 6 20% 10% 0% Prescribe Controversial Essential • 2 non-prescribers are in teaching hospitals, of whom one believes ECT is essential, though controversial; the other believes ECT to be both controversial and non-essential • All Private practitioners are ECT prescribers, though 4 of 5 who believe ECT to be controversial are private practitioners. Number of patients per week • Range in this sample from estimated 2 to 80 patients per week • Higher prescription levels were found in all settings. • Levels of prescription did not correlate with the practitioners’ view on whether ECT is a controversial treatment. • Furthermore, low prescription levels were also found in cases where practitioners viewed ECT as an essential treatment. • Therefore, levels of ECT may well be related to other factors, e.g. practice isolation and deskilling, equipment or human resource constraints, logistics, alternative treatments preferred by patients, etc. Indications for ECT 100% 0 0 90% 80% 10 70% 60% 15 17 50% 16 17 16 Series2 40% Series1 12 30% 7 20% 10% 2 1 1 1 1 0% Severe Mania OCD Catatonia Acute Schizophrenia, Depression Postpartum Psychosis Mild-Moderate Depression but Treatment resistant NMS Epileptic Fugue Agression Maintenance 41% 1 2 59% • No differentiation in Maintenance ECT prescription according to treatment setting was found. Modified ECT 0 1 2 17 ECT Suite/Theatre Resuscitation equipment, 0 Emergency drugs, 0 Suite, 4 1 2 Suite, 13 Emergency drugs, 17 Resuscitation equipment, 17 Monitoring during ECT 0 100% 3 90% 5 80% 8 9 10 70% 11 11 11 12 60% 17 50% Series2 14 Series1 40% 12 30% 9 8 7 20% 6 6 6 5 10% 0% EEG B/L & U/L Titration Dose Seizure Dose S/E's Dose Clinical length response Parameter ECG Oxymetry BP end-tidal CO2 Side effect Monitoring 17 18 16 13 14 11 12 10 Series1 n 8 6 4 2 0 Total Physical S/E's Cognitive S/E's • Cognitive Side-effects were reported to be mainly clinically monitored by usual interview. • 3 practitioners use the MMSE routinely for this purpose. Staff training Perception 4 1 2 12 • Of those practitioners who perceived that their staff were insufficiently trained, 2 (50%) were based at teaching hospitals and 2 (50%) were based in non-teaching, non-private practice hospitals. One practitioner abstained from answering this question. Conclusion • Wide variety in ECT prescription and practice • Not apparently related to practice setting • Opportunity is clear for collaboration in setting standards, training, protocol development, audit and research