Non-Suicidal Self-Injury: Description, Motivations, and Relationship to Suicide E. David Klonsky, PhD Associate Professor Department of Psychology University of British Columbia Non-Suicidal Self-Injury Common in youth and adolescents Can be confused for attempted suicide Has an important relationship to suicide risk Agenda What is Self-Injury Who Self-Injures Why People Self-Injure Relationship to Suicide A Preliminary Note What we know (many many studies) What we think (one or two studies) What we don’t know (no research yet) Agenda What is Self-Injury Who Self-Injures Why People Self-Injure Relationship to Suicide What is Self-Injury? Self-inflicted damage to body tissue Intentional No suicidal intent What is Self-Injury? Intentional, direct injuring of one’s body tissue without suicidal intent Also called: non-suicidal self-injury (NSSI), self-mutilation, self-injurious behavior, self-wounding, and deliberate self-harm. What is Self-Injury? Skin-cutting, burning, scratching, rubbing skin against rough surfaces, interfering with wound healing Does not include overdosing, eating disorder behaviors, alcohol/substance use, body piercings/tattoos* Variation in Self-Injury Frequency Methods Medical Severity Contexts Motivations Desire/Efforts to Stop Agenda What is Self-Injury Who Self-Injures Why People Self-Injure Relationship to Suicide Famous Self-Injurers Princess Diana Famous Self-Injurers Angelina Jolie Famous Self-Injurers Christina Ricci Famous Self-Injurers Drew Barrymore Famous Self-Injurers Johnny Depp Famous Self-Injurers Eminem Famous Self-Injurers Marsha Linehan Famous Self-Injurers Harry Potter’s Dobby Klonsky, E.D. & Laptook, R. (2007). Dobby had to iron his hands, sir! Self-inflicted cuts, burns, and bruises in Harry Potter. In the Psychology of Harry Potter. BenBella Books. Who Self-Injures? Young Adolescents 8% High-School 14 - 15% University Students 17% General Adult Population 4-6% Adolescent Inpatients 40 - 80% Klonsky, E.D. & Muehlenkamp, J.J. (2007). Self-injury: A research review for the practitioner. Journal of Clinical Psychology: In Session. Psychological Characteristics Negative Emotions/Emotion Dysregulation Depression Anxiety Anger Self-Directed Negative Emotion Suicide Ideation and Attempts Defining Characteristic Intense, Self-Directed Negative Emotions? What About Abuse Histories? “may be reenacting the abuse perpetrated on them” (Noll, 2003) “manifestation of sexual abuse” (Cavanaugh, 2002) Abuse “contributes heavily to the initiation of self-destructive behaviors” (van der Kolk, 1991) Child Sex Abuse and Self-Injury Analysis of 44 studies Median phi = 0.23 (small relationship) Klonsky, E.D. & Moyer, A. (2008). Childhood sexual abuse and non-suicidal self-injury: Metaanalysis. British Journal of Psychiatry. Child Sex Abuse and Self-Injury: Conclusion Abuse histories can contribute to negative emotions driving NSSI, but … … many who self-injure do not have abuse histories, and many with abuse histories do not self-injure. Agenda What is Self-Injury Who Self-Injures Why People Self-Injure Relationship to Suicide Why People Self-Injure: Theories Theory Description of Theory Anti-Dissociation To end the experience of depersonalization or dissociation Anti-Suicide To replace or compromise with the impulse to commit suicide Emotion Regulation To alleviate intense negative emotions Interpersonal Boundaries To assert one’s identity or a distinction between self and other Interpersonal Influence To seek help from or manipulate others Self Punishment To derogate or express anger towards oneself Sensation Seeking To generate excitement or exhilaration Sexual To control, distract from, or gratify uncomfortable sexual urges Why People Self-Injure: Research Sources of evidence 1) Reasons/motivations for self-injury 2) Experience of self-injury 3) Laboratory studies of proxies for self-injury Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Why People Self-Injure: Research Theory Evidence For Theory Anti-Dissociation R, R, R, r, r, r, P, p, -p Anti-Suicide R, r, r Emotion Regulation R, R, R, R, R, R, R, R, R, R, R, P, P, P, P, P, P, L, L, L Interpersonal Boundaries r, r Interpersonal Influence R, r, r, r, r, r, r, p, p Self Punishment R, R, R, R, R, R, r, r, r, r, r Sensation Seeking r, r, r, r, r Results of 18 studies of reasons [R, r], self-report of phenomenology [P, p], or laboratory data [L, l]. Why People Self-Injure: Research Primary sources of evidence 1) Reasons/motivations for self-injury 2) Experience of self-injury Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Why People Self-Injure: Research Primary sources of evidence 1) Reasons/motivations for self-injury 2) Experience of self-injury Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Emotion Regulation 50-95% of self-injurers “To release emotional pressure that builds up inside me” “To get rid of intolerable emotions” “To control how I am feeling” Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Self-Punishment More than 50% of self-injurers “To express anger at myself” “To punish myself” Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Anti-Suicide 3rd most common reason “To avoid the impulse to attempt suicide” “To stop suicidal ideation or attempts” “To stop me from killing myself” Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Anti-Dissociation/Depersonalization 4rd most common reason “To know I am capable of feeling physical pain” “To feel like myself again” “To feel real” Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Interpersonal Influence 5th most common reason “To let others know what I am going through” “To get those around me to understand what I’m going through” “To get reactions out of people” Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Sensation/Excitement Seeking 6th most common reason “To feel exhilarated” “I thought it would be fun” Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Why People Self-Injure: Research Primary sources of evidence 1) Reasons/motivations for self-injury 2) Experience of self-injury Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Why People Self-Injure: Research Primary sources of evidence 1) Reasons/motivations for self-injury 2) Experience of self-injury Klonsky, E.D. (2007). The functions of deliberate self-injury: A review of the evidence. Clinical Psychology Review. Emotions and Self-Injury 40 Emotions Before, During, and After Self-Injury Examples: Angry, Sad, Lonely, Frustrated, Worthless, Guilty Happy, Relieved, Hopeful, Satisfied Bored, Restless, Apathetic Unreal, Mesmerized, In a Trance Klonsky, E.D. (2009). The functions of self-injury in young adults who cut themselves: Clarifying the evidence for affect-regulation. Psychiatry Research. Emotions and Self-Injury Before Overwhelmed During Angry at Self After Relieved Sad Hurt Emotionally Isolated Angry at Self Calm Hurt Emotionally Low-Arousal Negative Emotions "Sad" 5 4 "Lonely" 3.5 2.9 3 3.0 2.9 Before After 2 1 High-Arousal Negative Emotions 5 "Overwhelmed" 4 3.6 3 "Anxious" 3.6 2.4 2.5 2 1 Before After Low-Arousal Positive Emotions 5 Relieved Calm 4 3.3 2.9 3 2 1 1.5 1.1 Before After Big Changes in Negative Arousal Emotion Cohen’s d Relieved +2.25 Calm +1.39 Overwhelmed - 0.89 Anxious - 0.81 Why People Self-Injure: Theories Theory Description of Theory Anti-Dissociation To end the experience of depersonalization or dissociation Anti-Suicide To replace or compromise with the impulse to commit suicide Emotion Regulation To alleviate intense negative emotions Interpersonal Boundaries To assert one’s identity or a distinction between self and other Interpersonal Influence To seek help from or manipulate others Self Punishment To derogate or express anger towards oneself Sensation Seeking To generate excitement or exhilaration Sexual To control, distract from, or gratify uncomfortable sexual urges Why People Self-Injure: Theories Theory Description of Theory Anti-Dissociation To end the experience of depersonalization or dissociation Anti-Suicide To replace or compromise with the impulse to commit suicide Emotion Regulation To alleviate intense negative emotions Interpersonal Boundaries To assert one’s identity or a distinction between self and other Interpersonal Influence To seek help from or manipulate others Self Punishment To derogate or express anger towards oneself Sensation Seeking To generate excitement or exhilaration Sexual To control, distract from, or gratify uncomfortable sexual urges Why People Self-Injure: Theories Theory Description of Theory Anti-Dissociation To end the experience of depersonalization or dissociation Anti-Suicide To replace or compromise with the impulse to commit suicide Emotion Regulation To alleviate intense negative arousal Interpersonal Boundaries To assert one’s identity or a distinction between self and other Interpersonal Influence To seek help from or manipulate others Self Punishment To derogate or express anger towards oneself Sensation Seeking To generate excitement or exhilaration Sexual To control, distract from, or gratify uncomfortable sexual urges Why People Self-Injure: Theories Theory Description of Theory Anti-Dissociation To end the experience of depersonalization or dissociation Anti-Suicide To replace or compromise with the impulse to commit suicide Emotion Regulation To alleviate intense negative arousal Interpersonal Boundaries To assert one’s identity or a distinction between self and other Interpersonal Influence To seek help from or manipulate others Self Punishment To derogate or express anger towards oneself Sensation Seeking To generate excitement or exhilaration Sexual To control, distract from, or gratify uncomfortable sexual urges Functions of Self-Injury 1. Organizing conceptual framework 2. Valid and comprehensive assessment Inventory of Statements about Self-injury (ISAS) Assesses 13 functions of NSSI Three items per function 39-item measure Klonsky, E.D. & Olino. T.O. (2008). Identifying clinically distinct subgroups of self-injurers among young adults: A latent class analysis. Journal of Consulting and Clinical Psychology. Klonsky, E.D. & Glenn, C.R. (2009). Assessing the functions of non-suicidal self-injury: Psychometric properties of the Inventory of Statements About Self-injury (ISAS). Journal of Psychopathology and Behavioral Assessment. Sample I-SAS items “When I harm myself, I am… Affect Regulation …calming myself down. Self-Punishment …expressing anger towards myself for being worthless or stupid. Anti-Suicide …putting a stop to suicidal thoughts. Anti-Dissociation …causing pain so I will stop feeling numb. Interpersonal Influence …letting others know the extent of my physical pain. Sensation Seeking …doing something to generate excitement or exhilaration. Peer Bonding …fitting in with others. Self-Care …creating a physical injury that is easier to care for than my emotional distress Marking Distress …creating a physical sign that I feel awful. Interpersonal Boundaries …creating a boundary between myself and others. Toughness …seeing if I can stand the pain. Revenge …getting back at someone. Autonomy …demonstrating I do not need to rely on others for help. Inventory of Statements about Self-injury (ISAS) 235 self-injurers from a college sample 18-19 yrs old, 57% female, 42% Caucasian Hitting self, biting, cutting, pinching, wound-picking ISAS Factor loadings (Exploratory Factor Analysis with Promax Rotation) Function Mean (SD) Social Functions Intrapersonal Functions Affect Regulation 3.0 (2.1) -.14 .69 Anti-Dissociation 1.0 (1.6) .21 .50 Anti-Suicide 0.8 (1.5) . 35 .42 Marking Distress 1.5 (1.8) .04 .82 Self-Punishment 2.0 (2.1) -.14 .84 Autonomy 0.6 (1.3) .64 .11 Interpersonal Boundaries 0.8 (1.4) .52 .26 Interpersonal Influence 0.8 (1.4) .54 .23 Peer Bonding 0.5 (1.3) .98 -.26 Revenge 0.6 (1.4) .53 .16 Self-Care 0.8 (1.4) .41 .33 Sensation Seeking 0.7 (1.3) .87 -.18 Toughness 1.0 (1.4) .65 .02 ISAS Factor loadings (Exploratory Factor Analysis with Promax Rotation) Function Mean (SD) Social Functions Intrapersonal Functions Affect Regulation 3.0 (2.1) -.14 .69 Anti-Dissociation 1.0 (1.6) .21 .50 Anti-Suicide 0.8 (1.5) . 35 .42 Marking Distress 1.5 (1.8) .04 .82 Self-Punishment 2.0 (2.1) -.14 .84 Autonomy 0.6 (1.3) .64 .11 Interpersonal Boundaries 0.8 (1.4) .52 .26 Interpersonal Influence 0.8 (1.4) .54 .23 Peer Bonding 0.5 (1.3) .98 -.26 Revenge 0.6 (1.4) .53 .16 Self-Care 0.8 (1.4) .41 .33 Sensation Seeking 0.7 (1.3) .87 -.18 Toughness 1.0 (1.4) .65 .02 Relationship of Functions to NSSI Frequency Social Functions NSSI Behavior Cutting Needle sticking Carving Banging/Hitting self α = .87 Intrapersonal Functions α = .80 .19 Note. All correlations are statistically significant at an alpha of .03. .30 .19 .18 .13 Relationship of Functions to Cutting Correlation with Cutting Affect Regulation Anti-Dissociation Anti-Suicide Marking Distress Self-Punishment Autonomy Interpersonal Boundaries Interpersonal Influence Peer Bonding Revenge Self-Care Sensation Seeking Toughness .21 .24 .24 .23 .22 .04 .04 .15 -.01 .09 .04 .06 .11 Note. Correlations above .20 are statistically significant at an alpha of .001. Relationship of Functions to Clinical Variables Clinical Variable Social Functions α = .87 Intrapersonal Functions α = .80 Depression .24 .42* Anxiety .33 .36 Borderline Personality Disorder .14 .43* Note. Correlations above .16 are statistically significant an at alpha level of .01. * Indicates correlations are significantly different at an alpha of .01. Relationship of Functions to Clinical and Contextual Variables Clinical/Contextual Variable Social Functions α = .87 Intrapersonal Functions α = .80 Suicidal Ideation .10 .32* Suicide Plans .14 .33* Attempted Suicide .12 .29* Note. Correlations above .16 are statistically significant an at alpha level of .01. * Indicates correlations are significantly different at an alpha of .01. ISAS in Alexian Brothers Hospital 108 psychiatric patients Ages 11 – 62, mean=19 90% female 72% Caucasian Function Social Intrapersonal Affect Regulation .77 Anti-Dissociation .62 Anti-Suicide .50 Marking Distress .75 Self-Punishment .67 Autonomy .55 Interpersonal Boundaries .44 Interpersonal Influence .51 Peer Bonding .95 Revenge .47 Self-Care .39 Sensation Seeking .71 Toughness .37 .41 .43 ISAS in an Adolescent Psychiatric Sample 80 psychiatric patients with NSSI from South Oaks Hospital in Long Island, NY Mean age = 15 (12 - 18) 70% female 61% Caucasian Function Social Intrapersonal Affect Regulation .87 Anti-Dissociation .83 Anti-Suicide .66 Marking Distress .63 Self-Punishment .77 Autonomy .79 Interpersonal Boundaries .69 Interpersonal Influence .54 Peer Bonding .77 Revenge .70 Self-Care .36 Sensation Seeking .73 Toughness .72 .37 FASM in Alexian Brothers Sample Item Social Receive more attention (S-P) .83 Get a reaction (S-P) .75 Feel more a part of a group (S-P) .74 Get parents to notice (S-P) .72 Get attention (S-P) .64 Avoid something unpleasant (S-N) .63 Avoid school/work/activities (S-N) .55 Intrapersonal Stop bad feelings (I-N) .68 Feel something (I-P) .68 Relive feeling numb/empty (I-N) .64 Punish self (I-P) .58 Feel relaxed (I-P) .54 Two Motivational Dimensions 1. Self-Focused 2. Other-Focused Two Motivational Dimensions 1. Self-Focused Affect Regulation Anti-Dissociation Anti-Suicide Marking Distress Self-Punishment 2. Other-Focused Two Motivational Dimensions 1. Self-Focused 2. Other-Focused Affect Regulation Interpersonal Influence Anti-Dissociation Peer Bonding Anti-Suicide Revenge Marking Distress Excitement Seeking Self-Punishment Toughness Two Motivational Dimensions 1. Self-Focused More Self-Injury More Psychopathology More Suicidality 2. Other-Focused NSSI Motivations: Summary 1. 2. 3. Most common motivations are emotion regulation and self-punishment NSSI motivations fall into two super-ordinate dimensions: 1) self-focused and 2) other-focused Self-focused motivations are associated with greatest clinical severity Agenda What is Self-Injury Who Self-Injures Why People Self-Injure Relationship to Suicide NSSI vs. Attempted Suicide Differ in terms of intent and medical severity Commonly co-occur Avoid oversimplified conclusions! Complex relationship needs careful study NSSI vs. Attempted Suicide NSSI sometimes mistaken for attempted suicide Unnecessary hospitalizations Harms case conceptualization Misallocates valuable resources NSSI conveys valuable information regarding suicide risk Results from 4 Studies: Does NSSI predict attempted suicide? Predictors of Attempted Suicide 139 Adolescent Psychiatric Inpatients Suicide Ideation NSSI .55 .50 Borderline Personality Disorder Depression Anxiety Impulsivity .37 .20 .16 .11 Predictors of Attempted Suicide 426 High-School Students Suicide Ideation NSSI .51 .38 Borderline Personality Disorder Depression Anxiety Impulsivity .29 .24 .18 .11 Predictors of Attempted Suicide 1,351 Undergraduates Suicide Ideation NSSI .44 .28 Borderline Personality Disorder Depression Anxiety Impulsivity .22 .24 .16 .10 Predictors of Attempted Suicide 438 United States Adults Suicide Ideation NSSI .36 .34 Summary of Results From Four Studies 1. 2. 3. 4. NSSI relates to attempted suicide NSSI relates to attempted suicide more strongly than other risk-factors NSSI is similar to suicide ideation in conferring risk for suicide Yet, like suicide ideation, many/most who engage in NSSI have not attempted suicide ?? Why does NSSI have such a strong relationship to attempted suicide? Thomas Joiner’s Interpersonal-Psychological Theory Desire + Capability Suicide ?? Most risk factors only confer desire Depression Hopelessness Suicidal ideation Others only confer capability Access to lethal means Combat exposure in military ?? NSSI confers both desire and capability Desire (intense negative emotions) Capability (habituation to self-inflicted violence) (Nock et al., 2006) NSSI is relatively unique among risk-factors in that it represents double-trouble! So what have we learned? Is NSSI a form of suicidal behavior? No! Is NSSI unrelated to attempted suicide? No! NSSI is different from attempted suicide, but confers strong suicide risk because it represents double-trouble (both desire + capability) Suicide: Take-Home Message NSSI is not attempted suicide, but… … People who self-injure are at greater risk for suicidal ideation … People who self-injure are more capable of acting on suicidal thoughts For more information… • Published 2011 • User-friendly information for health professionals Thank you Graduate Students Catherine Glenn Alexis May Sarah Victor Anita Hibbert Funding Sources National Institute of Mental Health American Foundation for Suicide Prevention Stony Brook University Center for Survey Research Thank you!! Questions, Comments, Discussion?? Extra Slides NSSI and BPD DSM-IV: NSSI is part of a BPD criterion DSM-5: NSSI proposed as own diagnostic entity What exactly is the relationship of NSSI to BPD? What BPD and NSSI Share Frequently co-occur Both have emotion dysregulation as a core feature Both associated with shame Can NSSI be Distinct from BPD? 198 Adolescent Psychiatric Inpatients Average of 3.3 Axis-I diagnoses Two Key Questions: 1. 2. Does BPD overlap with NSSI more than with other disorders? Does NSSI overlap with BPD more than with other disorders? Of those with BPD… … 78% NSSI … 84% Anxiety Disorder … 84% Disruptive Behavior Disorder (ODD or Conduct) … 78% Mood Disorder Of those with NSSI… … 52% BPD … 74% Anxiety Disorder … 73% ADHD … 66% Mood Disorder NSSI and BPD: Conclusions NSSI and BPD are correlated, but … Many who have BPD do not self-injure Many who self-injure do not have BPD Clinical Take-Home Message Diagnosis of BPD is not implied by presence of NSSI, but made through careful assessment on a case-by-case basis. Think of BPD and NSSI as you do Depression and Suicidality… … they often co-occur and even contribute to one another, yet are best view as distinct phenomena Agenda What is Self-Injury Who Self-Injures Why People Self-Injure Key Clinical Issues: Borderline Personality Disorder DSM-5 Suicide A Distinct NSSI Diagnosis? A symptom of a personality disorder in DSM-IV Proposed as a Behavioral Disorder for DSM-V 94 The Process Group of Experts Members from Mood Disorders and Child/Adolescent Disorders Workgroups Advisors with particular expertise in NSSI Lots of phone and email discussions Separateness Independent Clinical Significance Threshold Defining Characteristics Differentiation from other Behaviors/Disorders 95 And the proposed NSSI diagnosis is ……….. …not going to take effect in DSM-5 … but will appear in DSM-5 appendix as a research diagnosis A. In the last year, the individual has, on 5 or more days, engaged in intentional self-inflicted damage to the surface of his or her body, of a sort likely to induce bleeding or bruising or pain (e.g., cutting, burning, stabbing, hitting, excessive rubbing), for purposes not socially sanctioned (e.g., body piercing, tattooing, etc.), but performed with the expectation that the injury will lead to only minor or moderate physical harm. The absence of suicidal intent is either reported by the patient or can be inferred by frequent use of methods that the patient knows, by experience, not to have lethal potential. (When uncertain, code with NOS 2.) The behavior is not of a common and trivial nature, such as picking at a wound or nail biting. B. The intentional injury is associated with at least 2 of the following: 1. Negative feelings or thoughts, such as depression, anxiety, tension, anger, generalized distress, or self-criticism, occurring in the period immediately prior to the self-injurious act. 2. Prior to engaging in the act, a period of preoccupation with the intended behavior that is difficult to resist. 3. The urge to engage in self-injury occurs frequently, although it might not be acted upon. 4. The activity is engaged in with a purpose; this might be relief from a negative feeling/cognitive state or interpersonal difficulty or induction of a positive feeling state. The patient anticipates these will occur either during or immediately following the self-injury. 97 Agenda What is Self-Injury Who Self-Injures Why People Self-Injure Key Clinical Issues: Borderline Personality Disorder DSM-5 Suicide Some Overall Clinical Conclusions Treatment should emphasize Functions (functional assessment) Negative Emotions (emotion regulation skills) Self-criticism (cognitive techniques) Arousal regulation (exercise?) Careful Diagnosis Suicidality should be carefully monitored Choose your own adventure 1. Why do people choose NSSI and not something else? (role of self-derogation/criticism) 2. Physiologically speaking, how does NSSI work? 3. Is NSSI an ‘addictive’ behavior? 4. Why is physical pain reduced in NSSI? Many ways to cope with negative emotions … why self-injury? Self-Derogation Self-injurers consistently score high on measures of selfderogation, self-criticism, and low self-esteem Klonsky, Oltmanns, & Turkheimer, 2003, American Journal of Psychiatry; Klonsky & Muehlenkamp, 2007, Journal of Clinical Psychology/In Session; Glassman et al., 2007, Behaviour Research and Therapy) Self-punishment/self-directed anger is the second most common motivation for self-injury (Klonsky, 2007, Clinical Psychology Review) “To express anger at myself” (Klonsky, 2009, Psychiatry Research) NESD Theory For those high in negative emotionality (NE) and self-derogation (SD) … … Self-injury is an ego-syntonic regulation method … Self-injury uniquely fulfills a self punishment function NESD Model Temperament Intense self-derogation Self-injury Intense, negative emotions Environment Normative/Low self-derogation Other healthy & unhealthy coping NESD Theory Hypothesis: Those high in both negative emotionality (NE) and self-derogation (SD) are most likely to self-injure Predicts a statistical interaction between NE and SD in identifying self-injurers Sample 1: Young Adults 2,011 Air Force recruits in basic training Thomas, Turkheimer, & Oltmanns. (2003). Factorial structure of pathological personality traits as evaluated by peers. Journal of Abnormal Psychology. Mean age 20 (SD=5), 62% Male, 65% Caucasian, 17% African American Administered the Schedule for Nonadaptive and Adaptive Personality (SNAP; Clark, 1996) Self-Injury “When I get very tense, hurting myself physically somehow calms me down” “I have hurt myself on purpose several times” 1% endorsed both of these items Negative Emotionality SNAP Negative Temperament Scale 28 items: “I often have strong feelings such as anxiety or anger..” True-False format Self-Derogation SNAP Self-Derogation/Low Self-Esteem scale 7 items: “I’ve really made a mess of my life” True-False format Results Frequent Injurers Negative Emotionality (NE) 1.29 Self-Derogation (SD) 1.49 Control -.01 -.01 NE and SD interact to distinguish frequent cutters from controls (Binary Logistic Regression: Wald’s X2(1)=3.24, p=.07) Percentage of Frequent Self-Injurers in NESD Categories 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Low Both Low NE, High SD High NE, Low SD High Both Sample 2: Adolescents 432 high-school students Ages 13-17, 61% Female 53% Caucasian, 19% Hispanic, 15% Asian, 11% African American Self-Injury Section I of the Inventory of Statements About Self-injury (ISAS; Klonsky & Olino, 2008; Klonsky & Glenn, in press) Self-injurious behaviors done “intentionally” and “without suicidal intent” 12 different behaviors: “cutting,” “scratching,” “needlesticking” 6.5% Cut 3 or more times Negative Emotionality Composite of two measures 1. 2. Positive and Negative Affect Scale (PANAS; Watson & Clark, 1994) 10-items: “Upset,” “Ashamed,” “Irritable” [just NA scale] Difficulties in Emotion Regulation Scale (DERS; Gratz, 2004) 36-items: “When I’m upset, my emotions feel overwhelming” PANAS NA scale and DERS correlated r=.68 Self-Derogation Composite of three measures 1. 2. Self-Derogation scale from the Schedule for Nonadaptive and Adaptive Personality (SNAP; Clark, 1996) 7-items: “I’ve really made a mess of my life” Self-Perception Profile for Adolescents-Revised (SPPA; Harter, 1988; Wichstrom, 1995) Global Self-Worth 5-items: “often disappointed with [yourself]” Physical Appearance 5-items: “not happy with the way [you] look” Results Frequent Cutters Control Negative Emotionality (NE) 1.01 -.07 Self-Derogation (SD) 1.16 -.07 NE and SD interact to distinguish frequent cutters from controls (Binary Logistic Regression: Wald’s X2(1)=3.86, p<.05) Percentage of Frequent Skin-Cutters in NESD Categories 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Low Both Low NE, High SD High NE, Low SD High Both NESD Theory: Next Steps Preliminary evidence supports NESD theory Examine large group of severe self-injurers Consider functions of self-injury (e.g., Klonsky & Olino, 2008) How Does NSSI Work? Parasympathetic Rebound Theory Parasympathetic Rebound Theory Sympathetic nervous system – “fight or flight” Intense emotion: Fear, rage, panic Increases heart rate Increases blood flow to major muscle gruops Parasympathetic nervous system – “rest and digest” Limits effects of sympathetic system Slows heart rate Facilitates sustained engagement and attention Parasympathetic Impairment Inability to restrain sympathetic responses and emotions (panic, anger) Impaired parasympathetic activity observed in self-injury and Borderline Personality Disorder (Austin et al, 2007; Crowell et al., 2005; Weinberg, Hajcak, Klonsky, 2009) Parasympathetic Rebound Surges in sympathetic activity are followed by increases in parasympathetic activity What if surges are too strong or too weak? Too strong: fainting Too weak: emotional dysregulation observed in BPD and self-injurers Perhaps self-injury causes a surge in sympathetic activity which in turn triggers a strong parasympathetic rebound? Parasympathetic Rebound Some self-injurers report that seeing the blood is important for achieving calming influence of selfinjury (Glenn & Klonsky, 2010) Interestingly, the fainting response observed in blood phobics is often attributed to parasympathetic rebound The pain and blood caused by self-injury may both trigger a parasympathetic rebound Parasympathetic Activity Pre- and Post- Self-Injury 90 80 70 Mean RSA 60 50 40 30 20 10 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 Minutes NSSI Data from Matthew Nock, shown with permission (Nock & Mendes, in preparation)