Welcoming from the President
of AriSLA Foundation
The V edition of the scientific meeting of AriSLA
Foundation occurs during an exceptional
international context of fundraising and
increased awareness, due to the recent viral
and media campaign in favour of ALS research.
This unexpected event represent for all of us
a renewed challenge for continuing to invest
effort, genius and passion with the sole aim of
identifying new research perspectives that will
improve the understanding of the disease and
hopefully open soon to new therapies.
In particular, this year edition of our annual
AriSLA meeting will address the interesting
issue of new disease models, with the
participation of renown international experts,
whom I personally thank for their outstanding
contribution to the scientific debate.
Moreover, the new research perspectives also
include our own contribution, represented by
the translational research projects with high
potential for innovation that we have funded,
which will be orally communicated and
discussed during the Sessions.
The Congress Center of Cariplo Foundation
is located close to the “Teatro della Scala”
of Milan.
DIRECTIONS:
from Central Station:
MM linea 3 - stop Montenapoleone
MM linea 1 - stop Duomo
from Linate Airport:
bus 73 - stop San Babila (terminus)
MM linea 1 - stop Duomo
5thAnnual AriSLA Conference
NEW RESEARCH
PERSPECTIVE
For a future without ALS
September 26th 2014
www.centrocongressifondazionecariplo.it
centrocongressi@fondazionecariplo.it
Via Romagnosi, 8 - 20121 Milano
Centro Congressi Fondazione CARIPLO
Via Romagnosi, 8 - Milano
Cariplo Foundation
www.fondazionecariplo.it
I am sure that this year edition of our annual
conference will meet your expectations for an
interesting scientific up-to-date and will
represent the opportunity for an open debate
within the national ALS research community,
that AriSLA is proud to represent and sustain.
www.eventiarisla.org
Under the high patronage of the Italian Republic
Under the patronage of
Camera
dei Deputati
I wish you all a good job
FONDAZIONE ITALIANA DI RICERCA
PER LA SCLEROSI LATERALE AMIOTROFICA
Mario Melazzini
President of the AriSLA Foundation
FONDAZIONE ITALIANA DI RICERCA
PER LA SCLEROSI LATERALE AMIOTROFICA
www.arisla.org
Thanks to the donation of
Ministero della Salute
Scientific Program
08.30 – 09.00 am
Registration and welcome coffee
01.30 – 02.30 pm
Lunch
MORNING SESSION
09.00 – 09.30 am
Opening remarks and greetings from Institutions
Mario Melazzini - President of AriSLA Foundation
Beatrice Lorenzin* - Minister of Health
Roberto Maroni* - President of the Lombardy Region
Pierfrancesco Majorino - Councillor for Social Policies and
Health Services, City of Milan
01.30 – 03.00 pm
Poster Session - AriSLA Foundation ongoing projects
(to be evaluated by the Advisory Board members)
* Invited to participate
09.30 – 10.15 am
Neuroinflammation Fans the Flames
of Neurodegeneration: A Key to Clinical Diversity in ALS
S. H. Appel
AriSLA FOUNDATION ENDED PROJECTS
10.15 – 10.45 am
AriSLA Full Grant Project, Call 2010: iPSALS
iPS derived neural stem cells for Amyotrophic Lateral Sclerosis
G.P. Comi
10.45 – 11.15 am
AriSLA Full Grant Project, Call 2010: ALSMNDTDP-43
Molecular characterization of TDP-43 function in vivo and
the mechanisms that lead to motoneuron disease in
Drosophila models of ALS.
F. Feiguin
11.15 – 11.45 am
What have animal models taught us about ALS?
W. Robberecht
11.45 – 12.15 pm
Opportunities and Challenges for using iPS cells in ALS
Research
N. J. Maragakis
12.15 – 01.15 pm
Round Table: novel models for ALS research
S. H. Appel - L. Bruijn - G.P. Comi - B .G. M. Dickie
F. Feiguin - N. J. Maragakis - P. Pasinelli - G. Pompilio
W. Robberecht
01.15 – 01.30 pm
Presentation of the “AriSLA Call 2013” winner projects
AFTERNOON SESSION
AriSLA FOUNDATION ENDED PROJECTS
03.00 – 03.30 pm
AriSLA Full Grant Project, Call 2009: PRALS
P2X7 Receptor in Amyotrophic Lateral Sclerosis
N. D’Ambrosi
03.30 – 03.50 pm
AriSLA Pilot Grant Project, Call 2012: GOALS
Role of autoimmunity in ALS
P. Edomi
03.50 – 04.10 pm
AriSLA Pilot Grant Project, Call 2012: FUSinteractor
Biochemical and genetic analysis of the interaction
between FUS and NonA
G. Cestra
04.10 – 04.30 pm
AriSLA Pilot Grant Project, Call 2011: ALS-MAI
ALS: the role of Microglia, Astrocytes and Inflammation
L. Muzio
04.30 – 04.50 pm
AriSLA Pilot Grant Project, Call 2011: EcypALS
Extracellular cyclophilin A as a possible therapeutic target
for Amyotrophic Lateral Sclerosis
V. Bonetto
04.50 – 05.10 pm
AriSLA Pilot Grant Project, Call 2012: ALSsiMO
Antisense oligomer against SOD1 for the development of
ALS therapy
M. Nizzardo
05.10 – 05.30 pm
Closing remarks and Best Poster Prize
SPEAKERS
Stanley H. Appel
Methodist Neurological Institute, Houston, TX, U.S.
Valentina Bonetto
“Mario Negri” Institute for Pharmacological Research, Milan
Gianluca Cestra
IBPM National Research Council (CNR)
at “Sapienza University” of Rome
Giacomo P. Comi
Department of Pathophysiology Medical Surgical and
Transplant, University of Milan
Nadia D’Ambrosi
Institute of Neurobiology and Molecular Medicine,
National Research Council (CNR), Rome
Paolo Edomi
Department of Life Sciences, University of Trieste
Fabian Feiguin
International Center for Genetic Engineering
and Biotechnology (ICGEB), Trieste
Nicholas J. Maragakis
The Johns Hopkins Hospital, Baltimore, MD, U.S.
Luca Muzio
San Raffaele Foundation Center, Milan
Monica Nizzardo
Department of Pathophysiology Medical Surgical
and Transplant, University of Milan
Wim Robberecht
Vesalius Research Center, Flanders Institute
of Biotechnology (VIB), University of Leuven, Belgium
MODERATORS
Lucie Bruijn
The ALS Association, Washington DC, U.S.
Brian G.M. Dickie
MND Association, Northampton, UK
Piera Pasinelli
Thomas Jefferson University, PA, U.S.
and Packard Center for ALS Research,
Baltimore, MD, U.S.
Giulio Pompilio
AriSLA Foundation, Milan
FONDAZIONE ITALIANA DI RICERCA
PER LA SCLEROSI LATERALE AMIOTROFICA