Nu 615 – Advanced Pharmacology Part I
Module 1 Pharmacology Principles “Get You Thinking”
1. Define pharmacokinetic (PK) principles (ADME)
a. Absorption
b. Distribution
c. Metabolism
d. Excretion.
2. Define pharmacodynamics (PD)
3. What is pharmaceutics?
4. What is rate limiting?
5. What is the significance of CYP450?
6. How are drugs cleared from the body?
7. What is drug tolerance?
8. What is cross sensitization?
9. Define affinity, selectivity, therapeutic index, therapeutic window
10. Define agonists versus antagonists
11. What is receptor theory?
12. What is cholinergic response on systems in the body?
13. What are the phases of drug approval by the FDA?
14. What the DEA scheduled drug guidelines?
15. How can the advanced practice nurse address drug safety?
16. What factors influence prescribing drug therapy?
17. Explain the difference between an adverse reaction, allergic reaction, and a side effect.
18. State the difference between an enzyme inducer and an inhibitor in regards to drug
interactions.
19. Define the first-pass effect.
20. Discuss the principles of pain management
21. What is the gate control theory of pain?
22. Define types of pain
23. Drug therapy for mild to moderate pain (acute versus chronic)
24. Cox2 inhibitors
25. What are interventional techniques?
26. What drugs are considered controlled substance? See PowerPoint
27. What are issues with use of opioids?
28. What is a narcotic antagonist and what is the indication?
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