60- year- old
teacher
Antilipidemic
agents
Diuretic
Inhibits Na/Cl contransporter
(NCC) at distal convoluted
tubule
Thiazide
Statin (High- intensity)
Atorvastatin
Hydrochlorothiazide
Uses:
Hypertension via volume depletion
Heart failure
Nephrogenic diabetes insipidus
Nephrolithiasis from idiopathic
hypercalciuria
Side effects:
Hypercalcemia
Hyperglycemia
Hyperlipidemia
Hyponatremia
Allergic reactions
Uses:
Lowering of:
Serum LDL- C
Serum VLDL remnants
Plasma cholesterol
Triglycerides
Antihypertensive
Central pharmacological action,
leads to reduction in hepatic
glucose production via limiting
of gluconeogensis
Blocks angiotension II from
binding to AT1 receptor,
leading to vasodilation, and
decreased blood pressure and
heart strain
Angiotensin receptor
blocking agents
Metformin
Uses:
First line treatment for Type II
Diabetes Mellitus
Infertility in women with PCOS
Side effects:
Hepatotoxicity (incrased liver
enzymes)
Myopathy
Increase in:
HDL
Anti- diabetic
Biguanide
Competitive inhibition of
HMG- CoA reductase (leads to
increased LDL receptor,
uptake of LDL)
Losartan
Side effects:
Nausea
Indigestion
Abdominal cramping
Diarrhea
Interferes with glucose and bile salt
absorption
Uses:
Stroke prophylaxis
Diabetes mellitus
Decrease of cardiac output
Decrease of peripheral vascular
resistance
Side effects:
Headaches
Nausea
Emesis
Diarrhea
Joint pain