1 History of X-ray CT Systems "What is CT?" 1. Dawn of X-ray CT 2. Advances in CT scanning methods 2 Dawn of X-ray CT Around 1964: The English company EMI (Hounsfield) developed a CT scanner. 1973: EMI released a commercial model, the "MARK1". In Japan, Toshiba obtained the rights to sell and maintain this model. 1975: The first CT system in Japan was installed at Tokyo Women's Medical University Hospital. 3 Dawn of X-ray CT First-generation CT systems ハンスフィールド Data acquisition → 9 days Image reconstruction → 2.5 days External appearance of the experimental system 4 EMI MARK1 → Radiological Society of North America (1972) External appearance of the CT system 5 Image acquired using the EMI MARK1 → 5th International Congress of Neurological Surgery (1973) → Scan time 270 s 6 First clinical case in Japan → Tokyo Women's Medical University Hospital EMI 1000 1975 7 First head CT system developed in Japan 1975 → Fujita Health University (Hitachi) External appearance of the CT system 8 Other manufacturers following EMI (At the Radiological Society of North America in 1975) GE → Presented a third-generation CT system Scan time: 5 s EMI → Second-generation CT system Scan time: 20 s 9 Distribution of a budget totaling 10 billion yen Major order from The General Insurance Association of Japan (1976) CT scanners → Total 32 systems EMI scanners: 27 systems ACTA scanners: 5 systems 10 Multislice scanning (1976) EMI 1010 11 First whole-body CT system developed in Japan 1978 → National Cancer Center (Toshiba TCT-60A) External appearance of the CT system 12 Dawn of CT systems → Third-generation CT EMIgoesintoadecline (Exhibition of CT systems at the Radiological Society of North America in 1975) SYNTEX EMI G.E VARIAAN PFIZER(ACTA) AS&E PHILIPS HITACHI PICKER C.G.R ELSCINT OHIO NUCLEAR ARTRONIX NEUROSCAN SEARLE LITTON 13 Third-generation C T → HelicalC T SIEMENS G.E PICKER Toshiba HITACHI SHIMAZU 14 Birth of continuous rotation-type CT EMI EMI Medical GE (otherthan theUSA) B.I.R THORN EMI EMI Medical America Toshiba Started development of a continuous rotation-type CT scanner (1979) Release of the TCT-900S (1985) Fujita Health University Fukushima Medical University National Cancer Center Announcement of helical scanning (1989) 15 Principles of X-Ray CT The absorption of X-rays varies due to differences in the composition or thickness of anatomical structures as they pass through the human body. These variations in X-ray absorption are used to reconstruct images. 16 Principles of X-ray CT - configuration X-ray tube ref.det. Reconstruction processing Magnetic disk Detector Image DA converter DAS 17 X-ray CT - First generation (T/R method) First-generation CT-scanner (1/2) (translate / rotate) X-ray tube Translation movement Single Detector cell Data collection (X-ray) Rotation movement No Data collection 18 History ofC T systems First generation CT-scanner (2/2) • For the reconstruction we need a set of data obtained with parallel projection (also called : views) originating from all directions within 180o. • First the detector and tube move linear (translation), then a rotation (eg. 1o) followed by translation, etc 19 History ofC T systems Second generation CT-scanner (1/2) (translate / rotate) X-ray tube Translation movement Small Detector array (about 20 cells) Data collection (X-ray) Rotation movement No Data collection 20 Historyof C T Systems Second generation CT-scanner (2/2) • Very similar to first generation scanners, instead of a single cell an array of cells is used (~ 20 cells). • The scan time could be decreased to 1/10 th. • Still translation and rotation movements are used. 21 HistoryofC T systems Third generation CT-scanner (1/2) (rotate / rotate) X-ray tube Detector array Non-continuous rotation : CW and CCW rotation Continuous rotation : only CW rotation 22 History of C T systems Third generation CT-scanner (2/2) • The detectors (eg. 512) are mounted in an arc. • No translation movement necessary because the length of the linear path is covered by the detectors. • The scantime is again reduced. 23 X-ray CT - Third generation (R/R method) - X. ray tube Cables Disadvantages • Scanning takes a long time Rotation orbit Rotation orbit Detector because reverse rotation is required after every rotation. • Breath-holding is required for every rotation. Results in patient discomfort 24 X-ray CT - Third generation (R/R method) - Advantages • The X-ray tube and the detector can be Brush rotated continuously in a paired manner to acquire data. • Since reverse rotation is not required, the scan time can be reduced to 1/10 that of a conventional scanner and high-quality images can be obtained. Helical scan Slipring 25 Slipring method Power supply slipring HVSR: External generator LVSR: Generator mounted in the gantry Signal transmission/reception slipring Contact type or non-contact type (optical slipring) Power supply Control/processing system 26 HistoryofC T systems Fourth generation CT-scanner (1/3) Stationary / Rotate Detector ring Tube orbit Conventional system Nutate system Tube rotates, Detector is stationary (full ring of detectors) 27 History of C T Systems Conventional system Fourth generation CT-scanner (2/3) The tube rotates inside the detector ring. 28 History of C T systems Nutate system Fourth generation CT-scanner (3/3) Nutate mechanism (moves detector in x-ray beam) 29 X-ray CT - Fourth generation (S/R method) Sampling point of projection data during rotation X. ray tube <Disadvantages> • The positional relationships with the X-ray tube focus are not optimal, resulting in a reduction in X-ray utilization efficiency. • There are difficulties in X-ray Detector (600 to 2500 channels) collimation, and the system tends to be strongly affected by scattered Xrays. 30 X-ray CT - Fourth generation (N/R method) For the TCT-900S Advantage Fan beam Tube orbit • The diameter of the detector ring (detector element array) can be made smaller than that for the S/R method. X-ray source rotation orbit High spatial resolution Detector ring 31 Generations (scan methods) Translate/Rotate Pencil-type X-ray beam 3 to 4 minutes Rotate/Rotate Wide X-ray fan beam 2 to 10 s (1 s) Translate/Rotate Narrow X-ray fan beam 10 to 20 s Stationary/Rotate Wide X-ray fan beam 1s 32 Outline of CT systems 1. Standard configuration, reconstruction principles 2. Basic performance and component technologies • Advances in scan time • Advances in reconstruction time • Advances in resolution • Advances in tube capacity 3. Cutting-edge technologies 33 Advances in scan time 300 10 07 05 0 Helical 30 20 Multi 1 0 7 5 3 2 : Non-slipring CT ‘99 ‘98 ‘96 ‘94 ‘92 ‘90 ‘88 ‘86 ‘84 ‘82 ‘80 ‘78 ‘76 1. 0 0 .7 0.5 ‘74 Scan time (s) 200 : Slipring CT 34 Basic configuration (units) of an X-ray CT system Gantry Console Patient couch 35 High-voltage generator X-ray tube Scanning (data acquisition) Image display/processing /storage/filming Detector CPU/Disk Image reconstruction unit Data acquisition unit Data acquisition unit Raw data storage Image reconstruction 36 Basics of CT image reconstruction 37 General CT system Gantry Monitor RAW DATA Reconstructor IMAGE DATA Storage Medium 38 CT image reconstruction (data flow) TUBE Gantry DETECTOR DAS CALIBRATION DATA Pre-Proc RAW DATA Reconstructor Console IMAGE DATA 39 TUBE DETECTOR DAS CALIBRATION DATA Pre-Proc RAW DATA Reconstructor IMAGE DATA 40 TUBE REFERENCE DETECTOR FAN ANGLE ROTATION(900VIEW) FOV DETECTOR 896CH PROJECTION DATA(投影データ) 41 X-ray path T TUBE Collimator Wedge Slit x-ray beam Beamtrimmer Detector Detector 42 TUBE DETECTOR DAS CALIBRATION DATA Pre-Proc RAW DATA Reconstructor IMAGE DATA 43 Pre-Processing CALIBRATION DATA TUBE Input = Pure Raw Data DETECTOR DAS Pre-Proc RAW DATA Reconstructor IMAGE DATA Pre Processing functions : • Offset correction • Reference correction • Water Calibration • Air Calibration • FSMC Output = Raw Data 44 Reconstruction Flow (S&V) From DAS (Pure Raw Data) Pre Processing Reconstructor To HDD (Raw Data) Filtering Back Projection To Monitor and HDD. (Image Data) 45 Linear superposition method T T 46 Result of Lineair superposition method Original object Result of Lineair Superposition method Unsharp result IMPROVEMENT: Filtered Backprojection 47 Filtered Backprojection Measurement data Filter data Result after filtering Convolution 48 Filtered backprojection T T 49 Linear superposition vs. Filtered backprojection Original object Result of Linear Superposition method Result of Filtered backprojection 50 Viewing • The values in the backprojector memory are Hounsfield units (after Sir G.N. Hounsfield). • The definition of the Hounsfield unit is : x - H2O CT number = 1000 x −−−−−−−−− H2O 51 Advances in reconstruction time From still image to dynamic image 8 Time 7 6 (s) Still image 5 4 3 Real-time 2 1 Dynamic image 99 97 95 93 91 89 87 0 Year 52 Reduce contrast medium? Since the liver can be scanned in 2 s, if the timing of contrast enhancement is incorrect, it is possible that no slices are enhanced. → SureStart is essential. HU 2sec SEC 53 Realtime Reconstruction Realtime Realtime Helical Helical Real Real Prep Prep Stop 54 Real-time CT Continuous scan (0.75 s/rot.) Image reconstruction Immediate (0.5 s) Continuous image display (8 fps) 55 SureStart Pilot scan Real-time CT number CT number in the abdominal aorta Conventional CT number Time Scan start Scan Time 56 SureStart CT number Contrast medium curve DELAY Threshold Time Monitoring Scan start 57 Real-time fluoroscopy (CT fluoroscopy mode) • Biopsy procedures can be performed easily and safely under CT fluoroscopic guidance (image reconstruction and display: 3 fps, 30 mA to 50 mA) while observing images in real-time. • The local console permits the operator to perform various system operations during scanning, such as gantry tilting, couch-top sliding, couch vertical movement, and Xray ON/OFF. • X-ray exposure to the operator and patient is reduced. 58 Multislice CT fluoroscopy * 3-slice (plane) real-time reconstruction/display * Display at 8 fps for 3 slices * Reconstruction at 0.125 s x 3 slices * Improved accuracy in biopsy procedures * Reduced biopsy time * Enhanced safety 59 X-ray generation 60 Functions of X-ray generator MAINS IN TO XRAY TUBE Low Voltage Increase High Voltage: kV High Current Decrease Low Current: mA AC Rectify DC kV mA time Operator Controls 61 Basic circuit of X-ray generator AUTO TRANSFORMER TIMER HIGH VOLTAGE TRANSFORMER X-RAY TUBE RECTIFIER High Voltage Low Voltage Low Current High Current DC AC kV S mA CATHODE HEATER POWER LINE 62 Metal Section X-ray Tube Primary Electrons Metal Center Section ANODE 90 mA CATHODE 100 mA Secondary Electrons Center Section Lead 10 mA 90 mA 100 mA 63 Metal Section X-ray Tube (2 focus) Filament for Small Focus ANODE CATHODE Common Filament for Large Focus ANODE ANODE ANODE Filament for Small Focus Common Large Focus Small Focus Focal Spot Filament for Large Focus 64 Metal Section X-ray Tube (2 focus) Small Focus Large Focus – Lower power input (eg: 120kV 200mA) + High power input (eg: 120kV 300mA) + For small objects (thin slices) – Not for thin slices. 65 Heat produced in X-ray tube (1/3) kV mA Time Heat Produced Cooling Unit OIL Housing Anode Focal Spot 66 Heat produced in X-ray tube (3/3) HEAT HEAT Temperature 4000o 3000o 2000o 1000o 0o Small heat capacity Large heat capacity 67 OverLoad Protection (OLP) • OLP will protect the tube. It will prevent exposure if the tube is too hot. • OLP is calculated by the input kV, mA and time. This is expressed in Heat Units (HU). kHU = kV mA sec 1.4 • The X-ray tube specification will state the maximum amount of HU the tube can handle. Also a cooling curve is specified. 68 Anode heating and cooling curves CXB-200 (example) 120% 100% %OLP 80% 60% Cooling-rate Continuous Scan 120kv/100mA Continuous Scan 120kv/50mA 40% Scan 120kv/70mA/4s + 4s wait 20% 0% 0 4 8 12 16 20 24 28 32 time (minutes) 36 40 44 48 52 56 60 69 ‘86 ‘88 ‘90 ‘92 ‘94 ‘96 ‘98 ‘99 Advances in CT X-ray tube capacity ‘84 MHU ‘82 8 ‘80 6 ‘78 4 ‘76 2 0 ‘74 70 Liquid metal bearing (LM tube) • Large-capacityX-raytubewithahighcoolingrate Large-capacity X-ray tube with a high cooling rate In order to provide the X-ray output required for high-speed scanning as well as to minimize the cooling time, the "HeliCool" tube, which offers high cooling efficiency and a short cooling time, is installed. With the use of a liquid metal bearing, the HeliCool tube avoids the disadvantages of ball bearings (vibration, noise, instability, short service life, etc.) and achieves a maximum cooling rate of 864 kHU/min. • Rotating-anode design• - X-ray target consisting of molybdenum and tungsten - Rotor section - Bearing section • Bearingstructure Three-layer heat insulation mechanism - Herringbone-patterngroovesonthesurface - Shaftsectionandrotationsection Liquid galliumalloy • Rotation characteristics - Vibration: 0.002 G or less - Noise: 40 dB or less 71 Performance and resolution of CT systems 72 CT performance evaluation 1. Spatial resolution This is the ability to identify an object with a significantly different CT number (i.e., with a large difference in X-ray absorption) compared with surrounding tissues. This is also referred to as "high contrast resolution". 2. Density resolution This is the ability to identify an object with a slightly different CT number (i.e., with a small difference in X-ray absorption) compared with surrounding tissues. This is also referred to as "low contrast resolution". 3. Resolution in the axial direction This is the ability to discriminate objects in the axial direction in MPR images and 3D images. 4. Temporal resolution This is the ability of the CT system to complete scanning within a short time (shorter is better). This is evaluated from two viewpoints: scan time and scan cycle. 73 1. Spatial resolution <Evaluation method> •An acrylic phantom with holes measuring 0.3 mm to 0.5 mm in diameter is scanned to evaluate the system. The spatial resolution is calculated based on the diameters of the holes that can be identified in the image. • A high-resolution function (FC30, FC890, etc.) is used as the reconstruction function. 0.35mm ● 0.4mm Scanning 0.5mm 0.45mm High-contrast resolution phantom 74 250 ‘99 ‘98 ‘96 ‘94 ‘92 ‘90 ‘88 ‘86 ‘84 ‘82 ‘80 ‘78 ‘76 ‘74 Diameter of the hole that can be identified (mm ) Advances in spatial resolution 2.00 1.7 51.5 01.2 51.0 00.7 5 0.5 00. 75 Factors related to spatial resolution X-ray tube 1. Focus size 2. Detector channel width, number of channels Detector 3. High-resolution reconstruction method Q/Q reconstruction (offset reconstruction) 4. Number of views (angle sampling pitch) ) 76 MTF:Modulation TransferFunction Method for evaluating spatial resolution Evaluated in terms of frequency. Unit: Lp/cm Line pair 77 Reconstruction function MTF 2.00 1.80 1.60 1.40 1.20 1.00 0.80 FC01 FC10 FC20 FC30 F C 50-x FC70 FC80 0.60 0.40 0.20 0.00 78 2. Density resolution <Evaluation method> •A low-contrast phantom is scanned using standard scan conditions (120 kV, 200 mAs, 10 mm) to evaluate the system based on the differences in the contrast and diameter of the objects that can be identified. • Evaluation unit: %mm → An object with a diameter of 2 mm at 3% can be identified = 0.6%mm • The reconstruction functions used are those for the head and abdomen (FC20, FC43, etc.). 0.3% 0.5% Scanning 0.1% 1.0% Low-contrast resolution phantom 79 Factors related to density resolution 1. X-ray detectability Xe detector → Solid-state detector 2. X-ray beam quality (effective energy) Tube target, X-ray filter 3. Detector energy characteristics Xe detector → Solid-state detector 4. Electrical noise in the X-ray detection system 5. Image noise (Noise) 1/√¯(number of X-ray quanta) 80 Xenon detector (mech. 1/2) Incident radiation Entrance window Heater (34 °C / 40 °C) Xenon gas (10 .. 20 bar) High-Voltage electrode Collector electrode 81 Xenon detector (mech. 2/2) 100 .. 200V Signal 1 .. 2 A 82 Solid State Detector (SSD) (1/2) External Collimator Plate x-ray ch x ch x+1 ch x+2 ch x+3 ch x+4 ch x+5 ch x+6 ch x+7 to DDC Scintillator Internal Collimator i Light Photo diode 83 Solid State Detector (SSD) (2/2) •Collimator: External Collimator Plate – Molybdenum • 0.1mm thickness • 1.028 pitch • eliminate x-ray •Scintillator: to DDC Scintillator Internal Collimator Light i – material is secret • converts x-ray to visible light • too much x-ray can change the sensitivity •Photo diode: Photo diode • converts visible light to an electrical signal 84 Comparison of detector density resolution Xe detector Solid-state detector 85 Reconstruction function Image SD 70.0 60.0 50.0 40.0 30.0 20.0 10.0 0.0 Function 86 Processing to reduce image noise • Reconstruction function • Image filter 87 Advances in scan time 300 10 07 05 0 Helical 30 20 Multi 1 0 7 5 3 2 :Non-slipring CT ‘99 ‘98 ‘96 ‘94 ‘92 ‘90 ‘88 ‘86 ‘84 ‘82 ‘80 ‘78 ‘76 1. 0 0 .7 0.5 ‘74 Scan time (s) 200 :Slipring CT 88 What is helical scanning? [Principle] This is a scanning method in which the X-ray tube is rotated continuously while the patient is moved in the longitudinal direction. The tube therefore follows a helical path relative to the patient's body, permitting the rapid acquisition of continuous projection data. [Advances helping to make this scan method possible] 1. Slipring technology 2. High-voltage power transfer technology 3. High-speed couch movement control 4. Large-capacity, high-speed memory system 5. Interpolated reconstruction algorithm Axial direction 89 HelicalInterpolation 90 Principles of the 360 interpolation method Sub data area (180) Main data area (360) Sub data area (180) X-Ray Line B C A A C B Slice center position 91 Principles of the 180 opposed-beam interpolation method Main data area (360) Sub data area (Fan angle/2) Sub data area (Fan angle/2) X-Ray Line B b C A B AC b Slice center position 92 Relationship between the interpolation method and the effective slice thickness For 10 mm - 10 mm/r [%] 100 360 interpolation 180 interpolation 50 0 -15 -10 -5 0 5 [mm] 10 15 93 Differences in image quality due to the interpolation method 180 opposed-beam interpolation method 360 interpolation method 94 Usefulness of helical scan 1. Shorter scan time (a wide range can be scanned in a short time) 2. Improved scan accuracy (volume data is acquired) 3. Applicable to three-dimensional image diagnosis 95 Usefulness 1: Shorter scan time Helical scan Image acquisition Couch-top movement Couch-top sliding at 10 mm/s Image reconstruction Conventional scan 2.7-s scan Image acquisition Couch-top movement Couch-top movement Couch-top movement Couch-top movement Couch-top movement Couch-top movement Couch-top movement … Couch-top movement Couch-top movement 3-s Image reconstruction 96 Usefulness 2: Improved scan accuracy Helical scan Since volume data is acquired, this method is particularly useful for the visualization of small tumors. Conventional scan Since breath-holding is required in each scan, the organs tend to shift longitudinally. 97 Usefulness 3: Applicable to three-dimensional image diagnosis Helical scan Conventional scan An aneurysm measuring approximately 1 mm (which is difficult do depict in MRI studies) can be visualized. In helical scanning, continuous volume data can be acquired in a shorter time than in conventional scanning, thus making it possible to reconstruct a large number of images at smaller intervals. As a result, the courses of cerebral blood vessels and pulmonary blood vessels can be examined with high precision. 98 The source images are important when 3D images are generated! High-image-quality helical scan High-image-quality 3D processing 99 Helical Scan Helical scan can be used in many different ways : Single Helical Scan Serial Helical Scan Go & Return Helical Combined Helical Scan Tilted Helical Scan 100 CT scanning methods and exposure dose evaluation –Evaluation methods – 1. CTDI Single-sliceCT Conve Scan Single-sliceCT Helical Scan 2. HTDI 3. CTDI100 4. CTDIW 5. Other Multi-sliceCT Conve Scan Multi-sliceCT Helical Scan 101 CTDI:CT Dose Index 14scan Skin dose ● Dose at the center of the object ● 102 CTDI:CT Dose Index What is CTDI? This is obtained by dividing the integrated value of the dose profile (line integral dose) in the axial direction (Z-axis) in a single scan by the slice thickness and the number of slices. This value is obtained by converting the dose needed to acquire a single image in a single scan to a value per unit slice thickness. 103 HTDI:Helical Scanning CT Dose Index Skin dose ● Dose at the center of the object ● 104 CTDI 100 Skin dose ● 100mm Dose at the center of the object ● 105 CTDI:CT Dose Index Cylindrical phantom TLD probe TDL Dose profile 106 CTDI:CT Dose Index 1•2…13•14scan ● ● ● • Measurement method 1. Several TLD probes are arranged along the scan direction at the center and in surrounding areas of acrylic phantoms with diameters comparable to the human body (160 mm in diameter, 320 mm in diameter). 2. Scanning is performed for a total of 14 slices (7 slices each before and after the center of the phantom). 3. The value obtained by averaging the measurements obtained using the multiple TLD probes arranged in the scan range is the CTDI value. Dose profile 107 Conventional X-ray imaging and CT scanning: Differences in the X-ray exposure methods 108 CT exposure dose Single-sliceCT Conve Scan Center Head 18 Surrounding areas 20 Abdomen 6 10 (mGy) Single-sliceCT Helical Scan Center Head 15 Surrounding areas 17 Abdomen 5 8 (mGy) Converted to an equivalent value for 120 kV/100 mAs/10-mm slice. 109 Comparison with other examination methods skin dose • CT: Head · · · · · · · · · · · · · · · 60 mGy (conventional CTDI 300 mAs) Chest · · · · · · · · · · · · · · ·12 mGy (helical 150 mAs) Abdomen · · · · · · · · · · · 16 mGy (helical 200 mAs) • Fluoroscopy of the esophagus (per examination) · · · · · · · · · · 85 mGy • Fluoroscopy of the entire chest (per examination) · · · · · · · · · · 85 mGy • Fluoroscopy for barium enema (per examination) · · · · · · · · · · 200 mGy • Cardiac catheterization (per examination) · · · · · · · · · · 470 mGy 110 Leading-edge CT technologies 111 SINGLE-SLICE DETECTOR MULTI-SLICE DETECTOR 112 Differences in collimation Upper collimator X-ray tube Lower collimator The slice width is adjusted by the collimators. SINGLE-SLICE DETECTOR The slice width is adjusted by bundling detector elements. Data for multiple slices is acquired by bundling detector elements. MULTISLICE DETECTOR 113 Axial direction Equivalent to 20 mm Minimum slice thickness Minimum slice thickness 0.5 mm 4 rows 1.25 mm 4 rows Minimum slice thickness 0.5 mm 2 rows Toshiba GE SIEMENS Detector elements for 2.5-mm slice Detector elements for 5-mm slice Detector elements for 1.5-mm slice Detector elements for 5-mm slice Detector elements for 2.5-mm slice Detector elements for 1.5-mm slice Detector elements for 1-mm slice (2) 1.25mm x 16 seg. Geometric efficiency of 95% or more in the axial direction 0.5mm x 4seg. 1mm x 15seg. 1mm x 15seg. Comparisonofmultislicedetectorsoffered by various manufacturers Equivalent to 32 mm Equivalent to 20 mm 114 Multislice detector Single-slice detector Multislice detector Axial direction 115 Isotropic volume data Ba.Top An.0.5/3/0.5/160 Adeno Ca 0.5/3/0.5/256 気胸1/6/1/400 116 <Wide-range 3D diagnosis> Aquilion Multi Slice Slice thickness: 3-mm slice Helical pitch: 6 Scan time: 0.5 s Scan range: 1000 mm Total 30sec Xvigor Single Slice Slice thickness: 5-mm slice Helical pitch: 1 Scan time: 1s Scan range: 150 mm 117 Important points in gantry development 0.5-s high-speed scanning Centrifugal force = 13 G Example: X-ray tube 70 kg → 910 kgf A large load is applied to the rotation base due to centrifugal force. 0.5s/rot. The design must withstand high G (centrifugalforce). 118 Toensureabsolutesafety Adoption of a cylindrical rotation base Conventional rotation base Cylindrical rotation base The units in the rotation section are directly supported by the inner wall. It is impossible for the units to fly out. 119 Minimizing vibration and noise Adoption of the direct-drive method Belt-drive method Direct-drive method Motor Belt Direct-drive motor 120 Important points in X-ray tube development • Improvement in the ability to withstand high G forces Adoption of a design in which the target is supported at both ends • Increasing the heat capacity and cooling rate Adoption of an anodegrounded design (World's first anodegrounded X-ray tube for CT systems) 121 New-model X-ray tube • Compact design Same size as a conventional X-ray tube • Separation of the cooler from the Xray tube main unit Advantages in cost and maintenance Cooler X-ray tube main unit 122 Applications of the latest helical CT systems • IVR-CT system Xactive • Radiotherapy system CTport • For heavy particle radiotherapy Horizontal CT • Intraoperative CT Self-propelled helical CT • Mobile helical CT 123 Applications of the latest helical CT systems • IVR-CT system Xactive • Radiotherapy system CTport • For heavy particle radiotherapy Horizontal CT • Intraoperative CT Self-propelled helical CT • Mobile helical CT 124 Applications of the latest helical CT systems • IVR-CT system Xactive • Radiotherapy system CTport • For heavy particle radiotherapy Horizontal CT • Intraoperative CT Self-propelled helical CT • Mobile helical CT 125 Applications of the latest helical CT systems • IVR-CT system Xactive • Radiotherapy system CTport • For heavy particle radiotherapy Horizontal CT • Intraoperative CT Self-propelled helical CT • Mobile helical CT 126 Applications of the latest helical CT systems • IVR-CT system Xactive • Radiotherapy system CTport • For heavy particle radiotherapy Horizontal CT • Intraoperative CT Self-propelled helical CT • Mobile helical CT 127 Mass screening –The Tokyo Society for the Eradication of Lung Cancer – • Scan conditions: 120 kV, 50 mA (standard: 100 to 200 mA) • Slice thickness: 10 mm • Scan speed: 1 s/rot. • Couch-top movement speed: 20 mm/s Same level as for indirect radiography of the stomach 128 Findings detected by standard chest CT • Lesions of the mediastinum and large blood vessels Aortic aneurysms, mediastinal tumors, hilar lymphadenopathy, etc. • Lesions in the lung fields Lung cancers, shadows of pulmonary aneurysms, cysts, pleural lesions • Thoracic lesions Calcification, invasion of the chest wall by tumors, aneurysms, etc. 129 Improvements in CT performance and expansion of clinical applications Adoption of a two-dimensional Shorter scan time detector Example of clinical application Advantages etc. 1s • Widespread acceptance of helical scanning • Lung cancer screening • Routine use of real-time CT 0.75 s • Wider helical scan range (increased by 30%) • Improved real-time response in CT fluoroscopy Faster scan speed Larger number of slices acquired simultaneously •Lung cancer screening of the entire lung fields with a slice thickness of 10 mm • ECG-gated scanning • Reduced X-ray tube load • Improved throughput •Lung cancer screening in detailed examination mode •High-precision three-dimensional imaging over a wide range 130 Lung cancer screening using helical CT Background: • Increase in lung cancer mortality • Limited detectability of lung cancer by mass screening with chest X-ray • Widespread acceptance of helical CT and improved performance Purpose:Early detection of lung cancer Challenges: • Validation with regard to the relationship between exposure dose and effectiveness → Reduction in exposure dose • Reduced efficiency in image interpretation → Diagnostic support system 131 Concept of a CAD system for lung cancer CT screening Film or CRT Helical CT TOSHIBA CAD (W/S) Image data Suspected lung cancer Image interpretatio n Judgement ・This slice ・Biopsy ・Follow-up observation ・Other 132 Development of automatic lung cancer screening/diagnosis system 肺野領域の抽出 Visualization of the blood vessels 133 Detection of an abnormal shadow in contact with the chest wall Lesion Size? Roundness? Bone present in adjacent areas? Artifacts 134 Example of diagnostic results 135 Helical CT screening vehicle Mass screening vehicle in which a helical CT system is installed 136
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