05/05/2023, 09:27 Documents Downloader Sold to saokotbo@gmail.com https://documents-downloader.pages.dev/document 1/94 05/05/2023, 09:27 Documents Downloader None of the content provided within this e-book is to be deemed legal or medical advice in any way, shape or form. All decisions are yours alone and I am not responsible for your actions. This e-book is for educational purposes only. Do not take supplements or drugs without the supervision or direction of a qualified medical professional. Before deciding to use PEPTIDES, I suggest you do your own research alongside reading these opinions (not to be deemed medical advice). DISTRIBUTION Use, distribution or disclosure by others is prohibited. This product is not to be re-sold at any time. The illegal sale or distribution of this e-book will be prosecuted. RIGHTS RESERVED The materials contained in this product are protected by applicable copyright and trademark law. SARMSINFO is the author and owner of this product. MOST OF THESE PEPTIDES ARE NOT APPROVED FOR HUMAN CONSUMPTION. DO NOT TAKE THEM WITHOUT THE APPROVAL AND SUPERVISION OF YOUR DOCTOR. https://documents-downloader.pages.dev/document 2/94 05/05/2023, 09:27 Documents Downloader INTRODUCTION THE PEPTIDES ................................................................................................ BPC-157 .................................................................................................... 7 TB-500 ..................................................................................................... 12 MELANOTAN II ........................................................................................ 17 HGH FRAG 176-191/ AOD-9604 .............................................................. 24 CJC-1295 ................................................................................................ 28 IPAMORELIN ........................................................................................... 35 GHK-CU ................................................................................................... 43 DSIP ........................................................................................................ 49 PT-141 ..................................................................................................... 54 OTHER GHRPS ........................................................................................ 59 OTHER PEPTIDES ................................................................................... 61 HOW TO RECONSTITUTE & ADMINISTER PEPTIDES SAMPLE CYCLE LAY OUTS FREQUENTLY ASKED QUESTIONS SOURCES FURTHER READING REFERENCES 2 https://documents-downloader.pages.dev/document 3/94 05/05/2023, 09:27 Documents Downloader WHAT ARE PEPTIDES? Everyone knows what a protein is, but the same is not true about Peptides. Proteins are chains of 50 or more amino acids, whereas Peptides are chains of up to 50 amino acids, bound by “peptide bonds”. Peptides occur naturally and can be classified into dozens if not hundreds of categories. They can be found in all living organisms, including humans, plants and even fungi. But, if you are reading this e-book, you are probably interested in using peptides to improve your quality of life, your physical performance, your appearance and your health, so I will not bore you to death with biochemistry lessons. For the sake of simplicity, we will define Peptides as a class of research chemicals that can be used off-label to enhance performance and/or improve quality of life, which unlike SARMs and Anabolic Androgenic Steroids, are too diverse and different from each other to be classified into a single category. You can ask someone what the side-effects of AAS or SARMs are, and they will give you a broad but acceptable description of the most common side-effects that can occur after using these substances. As you work your way through this e-book, you will realize that the same question cannot be asked regarding Peptides, because they are too different from each 3 https://documents-downloader.pages.dev/document 4/94 05/05/2023, 09:27 Documents Downloader other and the only thing two random Peptides have in common is the fact that they are made up of less than 51 amino acids. ARE PEPTIDES SAFE? Even after I explain that Peptides are remarkably diverse and have little in common with each other, people keep asking me about their safety as if I could provide them with a universal answer. Some peptides are 100% safe, some peptides will accelerate cancer growth, some peptides will allow you to have a baby if you are infertile and some peptides will castrate you. So, are they safe? It depends on what you are taking, how much you are taking and for how long, among many other variables. If you are reading this, you are probably old and smart enough to understand my answer. But do not worry, I will explain the possible side-effects of every single Peptide that is covered in this e-book, so that you can decide whether to take it or not. ARE PEPTIDES LEGAL? The vast majority of Peptides covered in this e-book are classified as research chemicals that have not been approved for human consumption, meaning that you can acquire them legally for research purposes only. 4 https://documents-downloader.pages.dev/document 5/94 05/05/2023, 09:27 Documents Downloader IMPORTANT NOTICE As you may or may not know, some Peptides have gone through human clinical trials, while others have only been tested on animals. A big percentage of what we know about Peptides and their actions is not based on actual science, but on the anecdotal reports of thousands of users. In other words, the science on Peptides and other Research Chemicals is not settled yet. You will notice that next to each benefit and side-effect, I have included an A and/or a number between parentheses. An A letter means that what is claimed about the benefit or side-effect in question is based on anecdotal information. However, if next to the A there is also a number, part of what is claimed about that benefit or side-effect has been proven to be true by at least one clinical or animal trial, and you can find the specific trial(s) by going to the REFERENCES section at the end of this e-book. Please keep in mind that some benefits or side-effects have only been confirmed in animal trials, so we cannot extrapolate that information and confirm that they apply to humans as well. I want to make it clear that the content in this e-book should be seen as medical advice. You are responsible for your own actions and their consequences. 5 https://documents-downloader.pages.dev/document 6/94 05/05/2023, 09:27 Documents Downloader THE PEPTIDES 6 https://documents-downloader.pages.dev/document 7/94 05/05/2023, 09:27 Documents Downloader BPC-157 Half-life: Unknown Dose: 250-500mcg/day Cycle Length: As needed legalITY: Research Chem WADA: Not Banned is derived from a naturally occurring sequence of amino acids that can be found in gastric juices. In the world of PEDs, research chemicals and anti-aging medicine, BPC-157 is perhaps the most well-known and widely used Peptide (apart from HCG and HGH). This is an incredibly miraculous compound that can rapidly heal any injury by inducing what is known as “angiogenesis”, the formation of new blood vessels. Besides providing you with wolverine-like healing abilities, BPC-157 can also take your cognitive, digestive and cardiovascular health to the next level. 7 https://documents-downloader.pages.dev/document 8/94 05/05/2023, 09:27 Documents Downloader HEALING OF WOUNDS & BURNS (1) (A) Pre-clinical studies on rats have shown that BPC-157 is extremely effective at healing wounds and burns in record time. Anecdotal reports confirm these findings : People are not only successfully healing wounds and burns, but they are also healing bruises, scars and even mosquito bites. HEALING OF BONES & TENDONS (2) (a) Pre-clinical studies show that BPC-157 is comparable to bone marrow grafts when it comes to healing bones and treating osteoporosis. Pre-clinical studies have also shown that BPC157 can heal tendons almost completely, even in rats which would have never recovered without the use of this peptide. Anecdotal information confirms these findings yet again, with hundreds of users claiming that BPC-157 healed their fractured bones and/or their injured tendons, even after years of chronic pain. HEALING OF MUSCLES (3) (a) In rats, BPC-157 was effective at healing cut or torn muscles. Many bodybuilders who have used BPC-157 confirm that this peptide can speed up muscle recovery after an injury or 8 https://documents-downloader.pages.dev/document 9/94 05/05/2023, 09:27 Documents Downloader simply decrease the amount of muscle soreness they feel the day after a work-out. NEUROPROTECTION (4) (A) Multiple pre-clinical studies have been conducted to assess the effectiveness of BPC-157 at protecting the brain. It was shown to significantly reduce the negative consequences of brain injury, to heal nerve damage, to fight symptoms of depression and even protect the brain from seizures. Some people claim it helped them fight depression and reverse the cognitive damage caused by drug use. IMPROVED DIGESTIVE HEALTH (5) (A) Since BPC-157 is derived from a substance found in gastric juices, it does not come as a surprise that BPC-157 can play a significant role in digestive health. In pre-clinical studies, BPC-157 healed ulcers and fistulas while stabilizing gut flora. Anecdotal reports confirm that BPC-157 can do wonders for the digestive system, and by extension treat auto-immune diseases like IBD (Inflammatory Bowel Disease). OTHER BENEFITS (6) (A) Besides all the aforementioned benefits, BPC-157 can also act as a painkiller, reduce any kind of inflammation, balance 9 https://documents-downloader.pages.dev/document 10/94 05/05/2023, 09:27 Documents Downloader blood pressure and mitigate the negative effects of certain drugs. Since many enhanced bodybuilders will find BPC-157 interesting, it is also worth noting that it can protect the liver when using oral AAS or SARMs. CANCER GROWTH (7) Now, before you panic and completely discard BPC-157, hear me out. As I mentioned before, the healing benefits of BPC157 are due to angiogenesis (the formation of new blood vessels). This phenomenon is wonderful, but in people who already have cancer, it can accelerate the rate at which the tumour grows. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 10 https://documents-downloader.pages.dev/document 11/94 05/05/2023, 09:27 Documents Downloader BPC-157 is available in both oral and injectable formulations. A lot of people choose to take it orally because its more convenient, but the results one can expect from taking it orally are not comparable to what injections can provide. Taking it orally is particularly useful if you are trying to heal your digestive system, but when it comes to healing wounds, fractured bones, tendons and other injuries, it is simply not as effective as the injections. Note that it will still help, but you will need to take a large amount to get decent results. The normal oral dose is 500mcg (0.5mg) per day but going up to 1000mcg (1mg) per day might be necessary if you want to treat certain injuries effectively. The injectable administration is preferrable if there is a specific wound or injury that you would like to treat. Injecting BPC-157 subcutaneously close to the area that you are trying to treat is the most effective way to use it, since BPC-157 has great localized effects but mediocre systemic effects. When injecting BPC-157, injecting anywhere from 250mcg to 500mcg per day is recommended, depending on the severity of the injuries that you are trying to treat. You can either inject twice a day or just once a day. In terms of treatment length, BPC-157 should be used as needed. There is no need to cycle it for X weeks and then rest for X weeks. For example, if you cut your finger, simply use it daily until your finger is fully healed. 11 https://documents-downloader.pages.dev/document 12/94 05/05/2023, 09:27 Documents Downloader TB-500 Half-life: Unknown Dose: 1-2mg EOD Cycle Length: Up to 8 wk. Legality: Research Chem WADA: Banned is the synthetic version of a naturally occurring peptide known as Thymosin Beta-4, which can be found in many tissues throughout the body of most animals, including humans. Tβ4 plays various roles in the body, but it primarily acts as a tissue-regenerating and anti-inflammatory peptide. TB-500 is the most widely used form of Tβ4, and it has gained a decent amount of popularity among athletes and bodybuilders in recent years, mainly because it is sold as a peptide that can heal anything while increasing muscle mass and performance. As you will now see, these claims are not entirely true, but this is a miraculous compound nonetheless. 12 https://documents-downloader.pages.dev/document 13/94 05/05/2023, 09:27 Documents Downloader HEALING OF WOUNDS & BURNS (8) (A) Studies have shown that Thymosin Beta-4 is effective at healing wounds, cuts and burns by promoting the formation of new blood vessels and preventing the formation of scars and fibrosis by decreasing myofibroblast accumulation in wounds. In other words, TB-500 can heal wounds, cuts and burns more rapidly through the same mechanism as BPC-157, and it can prevent the build-up of scar tissue. Anecdotal reports confirm these findings, with some users reporting that TB-500 was more effective at healing their wounds than BPC-157. HEALING OF BONES & TENDONS (9) (a) Pre-clinical studies on mice have found that Thymosin Beta-4 can speed up the healing of bone fractures and ligaments. Anecdotal reports by athletes who have used TB-500 to heal these kinds of injuries confirms that these findings apply to humans as well. MUSCLE GROWTH (10) (a) It is often claimed that TB-500 can promote muscle growth, strength and endurance. While it can certainly heal muscular 13 https://documents-downloader.pages.dev/document 14/94 05/05/2023, 09:27 Documents Downloader injuries and promote the regeneration of muscle cells after exercise-induced stress, there is no substantial pre-clinical, clinical or anecdotal information to suggest that it can increase muscle mass and strength to a significant extent. NEUROPROTECTION (11) Some pre-clinical studies indicate that Thymosin Beta-4 might be effective at mitigating the damaged dealt by brain injuries and attenuating brain cell dysfunction. OTHER BENEFITS (12) (A) Thymosin Beta-4 also acts as a potent anti-inflammatory, and it can heal/protect the liver and the kidneys, making it a good addition to any SARM or AAS cycle. Furthermore, it has been shown to fight hyperglycemia and improve insulin sensitivity. There is also scientific data to suggest that Thymosin Beta-4 has cardioprotective properties, mainly because it can prevent fibrosis and cardiac ischemia. 14 https://documents-downloader.pages.dev/document 15/94 05/05/2023, 09:27 Documents Downloader CANCER RISK (13) There is a lot of controversy regarding T β4 and its role in cancer. Some studies have found elevated concentrations of Thymosin Beta-4 in cancer cells, which has led scientists to believe that it plays a role in the development of cancer while others suggest that the elevated concentrations of this peptide is part of the body’s response to cancer. What is clear, however, is that Thymosin Beta-4 promotes angiogenesis (the formation of new blood vessels) like BPC157, so both compounds are risky when it comes to growing existing tumours. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 15 https://documents-downloader.pages.dev/document 16/94 05/05/2023, 09:27 Documents Downloader There is a lot of contradictory information about how to use TB-500. We do not know what the exact half-life is, but we know that it is way longer than that of BPC-157, so daily injections are not required. Some people advocate for EOD (every other day) injections or even E3D (every 3 days). I personally find EOD injections to be more stable, so that is what I recommend. Regarding dosing, I find that injecting 1 to 2mg (dose depending on the severity of what you are trying to treat) every other day does the trick. Like BPC-157 which is mostly used as needed to treat specific injuries, TB-500 can be used only for as long as necessary, but some people get great results from cycling it for up to 8 weeks. If you are just trying to heal something, just use it EOD until you are fully healed. Alternatively, if you are taking it for improved mobility and physical performance, you may want to cycle it for up to 8 weeks. Some people choose to take a high dose during the first half of the cycle, followed by a lower, maintenance dose during the second half of the cycle. Oral formulations of TB-500 exist but based on anecdotal information it is safe to say that they are not remarkably effective. Unlike BPC-157, TB-500 does not need to be injected close to the area you wish to treat because it acts systematically. I recommend subcutaneous belly fat injections. 16 https://documents-downloader.pages.dev/document 17/94 05/05/2023, 09:27 Documents Downloader MELANOTAN-II Half-life: 1.5 hr (in rats) Dose: 75-250mcg EOD Cycle Length: ---------Legality: Research Chem WADA: Not banned is an infamous peptide used for cosmetic and sexual-enhancing purposes. It is a synthetic analogue of a naturally occurring peptide hormone known as α-MSH, a melanocyte-stimulating hormone that stimulates melanogenesis (production of melanin) and regulates sexual function. Even though it is mainly used by people who wish to get a good tan more rapidly and without the need to spend hours under the sun, Melanotan II has other benefits that are often overlooked. Keep reading to learn what these benefits are and what potential side-effects this extravagant compound has. 17 https://documents-downloader.pages.dev/document 18/94 05/05/2023, 09:27 Documents Downloader TANNING (14) (A) Melanotan II acts as an agonist of the melanocortin receptors, where it induces melanogenesis to increase melanin production. Melanin is responsible for the tan, which is a selfdefense mechanism that the body uses to protect the skin from UV radiation. In other words, Melanotan-II will give you a tan while also protecting your skin from UV radiation. It is not uncommon for people with very pale skin who would usually get sunburnt, to get a decent tan with Melanotan-II. This makes this peptide an excellent choice for people who have always struggled to get a bronzed skin tone, but people who can already get a decent tan can still benefit from Melanotan-II because it allows them to save time and lower the chances of getting wrinkles or even skin cancer due to sun-exposure. Some people have reported that Melanotan-II worked for them even with 0 sun exposure. IMPROVED SEXUAL FUNCTION (15) (a) Melanotan-II is known for improving blood flow, which contributes to enhancing erections. Furthermore, it has been found to enhance sexual desire and arousal in females. Anecdotal reports confirm these findings. 18 https://documents-downloader.pages.dev/document 19/94 05/05/2023, 09:27 Documents Downloader FAT LOSS (16) (a) One benefit of Melanotan-II that is often overlooked is its ability to cause weight loss by reducing abdominal fat. There is scientific evidence to support this claim, but in the real world it is not so clear whether Melanotan-II can lead to fat loss or not. Some users claim it does, while others claim they could not tell the difference. It can also stimulate the production of thyroid hormones (which would contribute to fat loss). Some people experience appetite suppression, which makes losing weight a lot easier. ANTI-INFLAMMATion (17) Melanotan-II is a synthetic analogue of α-MSH, which has been found to reduce brain inflammation and have anti-fungal and anti-microbial properties. OTHER BENEFITS (18) (A) Melanotan-II can lower blood glucose levels and improve insulin sensitivity. Some studies suggest that it might help with stroke recovery, neuroprotection and even the reversal of “autistic features”. 19 https://documents-downloader.pages.dev/document 20/94 05/05/2023, 09:27 Documents Downloader SKIN-RELATED SIDE-EFFECTS (19) (A) Almost all skin-related side-effects of Melanotan-II are due to using a high dose from day one. If you let you body adapt to this peptide by working your way up to the high doses, you can significantly reduce the severity of these side-effects or even avoid them completely: - Increase in the size of existing moles and freckles Growth of new moles and freckles. Lips become purple. Face flushing after injection. Nausea (not skin-related but happens when using too much Melanotan-II). - Priapism, long-lasting erection that can have serious consequences (not skin-related but possible if you overdose). One case study found that a woman developed melanoma (skin cancer) after abusing Melanotan-II and tanning beds for for a month. There is no evidence to suggest that this peptide can directly cause skin cancer, and in fact it was developed to reduce the chances of skin cancer happening, something that it achieves by increasing melanin production (which leads to greater UV protection) and reducing the amount of time people spend under the sun. 20 https://documents-downloader.pages.dev/document 21/94 05/05/2023, 09:27 Documents Downloader GENERAL SIDE-EFFECTS (20) (A) The following side-effects are mentioned in scientific papers and anecdotal information confirms that some of them are possible: - Increase in prolactin levels. Depression. Worse sleep (by lowering GABA). Stress/Anxiety. Kidney damage Rhabdomyolysis While these side-effects are definitely possible, they rarely happen to Melanotan-II users IF the dose/protocol is reasonable. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 21 https://documents-downloader.pages.dev/document 22/94 05/05/2023, 09:27 Documents Downloader You will find injectable and intranasal spray formulations of Melanotan-II. Both work quite well, in my experience the intranasal spray is less likely to cause nausea or skin flushing, but the bioavailability is not as good, so you’ll need to take 2x what you’d be injecting if you want to achieve the same results, and this can drive up the total price of the protocol. The following protocol is what I would recommend to someone who is going to be injecting Melanotan-II, if you are using it intranasally just do the exact same but with double the dose: Start by injecting 75mcg subcutaneously every other day, preferably 30-60 minutes before tanning. If after 3 injections you have not experienced any adverse side-effects, you can increase the dose up to 125mcg, and repeat the same process with the same dosing frequency. 6 injections later, if you have not experienced any significant side-effects like dark purples or a new collection of freckles, you can increase the dose all the way up to 250mcg and keep injecting until you reach your desired skin tone. If you reach your desired skin tone at 125mcg or even 75mcg, there is no need for you to keep increasing the dose. By the same token, if after a couple of weeks at 250mcg you have not reached your desired tan, you can increase the dose up to 300-350 and repeat the same process until you have reached your ideal tan, with conservative dose increases every 2 weeks, if necessary. 22 https://documents-downloader.pages.dev/document 23/94 05/05/2023, 09:27 Documents Downloader Once you have a skin tone that you are happy with, you can stop following this protocol and do maintenance by injecting once every 5 days whatever you were injecting EOD. For example, if at 125mcg you reach your ideal tan, you can then stop injecting 125 EOD and inject 125 E5D instead, without altering the tanning frequency. When using this peptide, you will not have to be under the sun or inside a tanning bed for more than 30-60 minutes or 10-15 minutes, respectively. 23 https://documents-downloader.pages.dev/document 24/94 05/05/2023, 09:27 Documents Downloader FRAG. 176-191 AOD-9604 Half-life: < 1 Hour Dose: 500mcg/day Cycle Length: 3 on 1 off Legality: Research Chem WADA: Banned is a synthetic peptide derived from Human Growth Hormone. HGH plays many different roles in the body and is made up of 191 amino acids. Of that 191 amino acid chain, the portion that goes from the 176th to the 191st is responsible for lipolysis, the breakdown of fats. By separating this part of the chain from the rest of the amino acids that make up HGH, Frag. 176-191 is obtained. A peptide that has all the fat-loss benefits of regular HGH, without any of the other effects. A slightly different peptide named (Frag. 177-191 + Tyrosine) is often mislabelled as Frag 176-191 and vice versa. They are similar enough to be interchangeable, so I will be using studies on AOD as a reference. 24 https://documents-downloader.pages.dev/document 25/94 05/05/2023, 09:27 Documents Downloader FAT LOSS (21) (A) These peptides will have a significant impact on your fat loss by inducing lipolysis. This phenomenon causes the mobilization of fat cells to be used as a source of energy when one is fasted. In other words, Frag. 176-191 and AOD-9604 will allow you to use a lot more fat as energy when you are fasted, resulting in a greater amount of fat loss. If you go to bodybuilding forums and look at people’s reviews of these peptides, you will find that people either love them or hate them. A lot of people do not use them properly, or their source is selling crap, so they think that these peptides are useless. It is entirely possible that some people are nonresponders, but most people who have used quality Frag. 176-191 / AOD-9604 and have followed a good protocol will tell you that they were blown away by how effective it was at helping them lose fat. OTHER BENEFITS (A) Some users claim that Frag.176-191 / AOD-9604 increased their IGF-1 levels, improved their sleep significantly and increased their appetite. There is no scientific data to suggest that these effects can happen with these peptides, so I am inclined to believe that these users were sold something else. Improved Cholesterol levels have also been reported. 25 https://documents-downloader.pages.dev/document 26/94 05/05/2023, 09:27 Documents Downloader GENERAL SIDE-EFFECTS (22) These peptides are almost free of side-effects. The only relevant “side-effect” is a modest increase in blood glucose levels which, as shown in studies, does not cause any longterm insulin resistance issues. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 26 https://documents-downloader.pages.dev/document 27/94 05/05/2023, 09:27 Documents Downloader The key to getting good results from Frag. 176-191 and AOD is following a good protocol. There are tons of PEDs that will provide amazing results even if your dosing protocol is suboptimal, but with these two peptides, you either get it right and have great results or you get it wrong and experience 0 benefits. There are a bunch of good protocols, but I personally like to do the following (500mcg/day). The first 250mcg should be injected upon waking up, with a completely empty stomach, followed by a 4-hour fast. If you break that 4-hour fast, you will ruin the effects of Frag. 176191 / AOD-9604. If you want to maximize the effects, do some exercise or cardio while fasting. The second 250mcg injection should be carried out before bed, 3-4 hours after your last meal. Therefore, if you had dinner at 8pm or 9pm, you should inject at midnight and then go to bed. After 20 days of following this protocol, I like to take a 10-day break, followed by another 20 days on (if necessary, to reach my goals). Do not take supplements during the fasting periods, the fillers / oils in capsules could potentially ruin the effects of the peptide. These peptides can be used orally, but the bioavailability is lower so a greater dose (2-4x) is necessary (very expensive). 27 https://documents-downloader.pages.dev/document 28/94 05/05/2023, 09:27 Documents Downloader Cjc-1295 Half-life: 6-8 days Dose: 2mg/week Cycle Length: 8-12 weeks Legality: Research Chem WADA: Banned is a synthetic peptide analogue of GHRH (Growth Hormone Releasing Hormone), which is an endogenous hormone that stimulates GH production in a pulsatile fashion. There are two “types” of CJC-1295. The main one, which we will be covering here, is CJC-1295 with DAC, and the other one is ModGRF (1-29), also known as CJC-1295 without DAC. The addition of “DAC” (Drug Affinity Complex) extends the half-life of this peptide and makes it more effective and convenient to use for performance-enhancing purposes. By causing significant increases in GH and IGF-1 levels, CJC1295 can increase your muscle mass, burn a ton of fat and improve your quality of life in multiple ways. 28 https://documents-downloader.pages.dev/document 29/94 05/05/2023, 09:27 Documents Downloader GAINS IN LEAN MUSCLE MASS (23) (A) CJC-1295 will increase endogenous IGF-1 levels. This is one of the most anabolic hormones in the human body, which can increase protein synthesis and is believed to contribute to muscular hyperplasia (the creation of new muscle cells). As confirmed by anecdotal information, using CJC-1295 for prolonged periods of time leads to a modest but significant increase in lean muscle mass, as long as training and diet are on point. FAT LOSS (24) (A) By increasing endogenous GH secretion, CJC-1295 can accelerate fat loss though lipolysis, the same phenomenon that makes Frag. 176-191, regular HGH and GH secretagogues so effective at burning fat. Some users claim that CJC-1295 allowed them to burn more fat than Frag. 176-191 and other GH peptides. ANTI-AGING (25) (A) Both GH and IGF-1 play important roles in improving longevity of youthfulness. They have been proven to not only extend 29 https://documents-downloader.pages.dev/document 30/94 05/05/2023, 09:27 Documents Downloader one’s lifespan, but to also improve quality of life by improving mobility, bone strength and muscle mass. By increasing GH and IGF-1 levels, CJC-1295 contributes to extending one’s lifespan and quality of life. You can also expect the quality of your REM sleep to improve significantly, which also contributes to your recovery. FASTER HEALING (26) (A) As you probably know, having optimal GH (and to some extent IGF-1) levels is key when trying to heal a wound, burn, cut or bone fracture. GH also plays an important role in keeping your joints healthy and lubricated. As mentioned before, these two hormones also increase bone strength and density. By causing supraphysiological increases in GH and IGF-1 levels, CJC-1295 can speed up the healing of any lesion and accelerate physical/muscular recovery after intense exercise. COSMETIC BENEFITS (27) (A) GH and IGF-1 will increase collagen production and give your skin that glow and elasticity that it has lost over the years. The same goes for hair, beard and nails. These will grow faster, healthier and stronger when using CJC-1295. 30 https://documents-downloader.pages.dev/document 31/94 05/05/2023, 09:27 Documents Downloader OTHER BENEFITS (28) (A) By increasing GH and IGF-1 levels, you can expect CJC-1295 to: - Decrease inflammation. Improve your immune response. Act as an antioxidant. Fight neurodegeneration and improve memory. Improve cardiovascular health. 31 https://documents-downloader.pages.dev/document 32/94 05/05/2023, 09:27 Documents Downloader UNSTABLE BLOOD GLUCOSE LEVELS (29) (A) Growth Hormone is known for increasing blood sugar levels. When taking CJC-1295, this is something you have to keep an eye on, especially if you diet is carb-heavy. I recommend taking around 300mg of Berberine before every meal containing a decent amount of carbs (50g+) when cycling CJC. WATER RETENTION (A) CJC-1295 will cause some degree of water retention, which can lead to high blood pressure and in some cases edema. You can mitigate this side-effect by decreasing your carb and sodium intake, eating foods rich in potassium and supplementing with Dandelion Root (500mg / day) or just taking a natural diuretic blend like “Water Out” by Now Foods. OTHER SIDE-EFFECTS (30) (A) Some people report feeling lethargic. Feelings of numbness/tingling in some extremities is also common with anything that increase GH levels. Lethargy is usually resolved by lowering the dose, whereas numbness usually goes away when you implement measures to bring down water retention. 32 https://documents-downloader.pages.dev/document 33/94 05/05/2023, 09:27 Documents Downloader Having chronically elevated GH levels for long periods of time can lead to the growth of certain body parts such as hands, feet, nose and even internal organs. CANCEr gROWTH RISK (31) (A) GH and IGF-1 will accelerate the growth of existing cancer cells, so this peptide and any other substance that increases circulating levels of these hormones could be lethal for anyone who has cancer. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 33 https://documents-downloader.pages.dev/document 34/94 05/05/2023, 09:27 Documents Downloader Thanks to its long half-life, CJC-1295 is extremely easy to use and does not require daily injections like most peptides do. The optimal weekly dosage is 2mg, which you can inject once a week, or twice a week, depending on how stable you want your levels to be, I personally find once a week to be enough. Due to the nature of this peptide, you want to inject it subcutaneously (belly fat) before bed because during the first few hours after an injection you would experience dizziness and flu-like symptoms, which you can sleep through and not notice. By fasting the next morning, you will reap all the fatburning benefits of this peptide. Regarding cycle length, there is not a one-size-fits-all answer. If you are using it for healing a specific injury, gaining some muscle or burning fat, I would not exceed the 12 weeks mark. Always rest for at least 4-6 weeks between CJC cycles. If you are using it to for anti-aging purposes, you may want to run it for much longer but at a lower dose. Some people have successfully used this compound non-stop for more than 6 months. This peptide is extremely synergistic with MK-677, Ipamorelin and other Growth Hormone secretagogues because it acts through a different pathway. This type of combination leads to having ridiculously high IGF-1 levels. You will find more information on how to stack CJC-1295 with GH secretagogues later on in this ebook. 34 https://documents-downloader.pages.dev/document 35/94 05/05/2023, 09:27 Documents Downloader IPAMORELIN Half-life: 2 hours Dose: 150-300mcg/day Cycle Length: 8-12 weeks Legality: Research Chem WADA: Banned is a peptide agonist of the Ghrelin receptor that acts as a Growth Hormone Secretagogue. Like other drugs of this class, it stimulates the secretion of GH and increases endogenous IGF-1 levels, making it an effective performanceenhancing drug. One could argue that Ipamorelin is like injectable MK-677 with a short half-life, which explains why it is so unpopular compared to the oral GH secretagogue par excellence. Due to being rather inconvenient, it is rarely used on its own for purposes other than anti-aging. When used as a PED, it is almost always stacked with CJC-1295, which leads to an absurd increase in IGF-1 & GH levels since both peptides increase these hormones through different pathways. 35 https://documents-downloader.pages.dev/document 36/94 05/05/2023, 09:27 Documents Downloader GAINS IN LEAN MUSCLE MASS (32) (A) Like other drugs of its class, Ipamorelin will increase IGF-1 levels, leading to an increase in lean muscle mass and new muscle cells (hyperplasia) over time. People who have used Ipamorelin report modest but noticeable gains in lean muscle mass, and insanely good pumps when stacking it with CJC-1295. FAT LOSS (33) (A) As you should know by now if you have been paying attention while reading this e-book, GH is extremely effective at burning fat by inducing lipolysis. As a GH secretagogue, Ipamorelin is no exception. You can expect faster fat loss if you use Ipamorelin and time it properly (more info in the “How to Use It” section). ANTI-AGING (34) (A) Both GH and IGF-1 play important roles in improving longevity of youthfulness. They have been proven to not only extend one’s lifespan, but to also improve quality of life by improving mobility, bone strength and muscle mass. 36 https://documents-downloader.pages.dev/document 37/94 05/05/2023, 09:27 Documents Downloader By increasing GH and IGF-1 levels, Ipamorelin contributes to extending one’s lifespan and quality of life. You can also expect the quality of your REM sleep to improve significantly if you administer it before bed. FASTER HEALING (35) (A) Having optimal GH (and to some extent IGF-1) levels is key when trying to heal a wound, burn, cut or bone fracture. GH also plays an important role in keeping your joints healthy and lubricated. As mentioned before, these two hormones also increase bone strength and density. By causing supraphysiological increases in GH and IGF-1 levels, regular Ipamorelin use can speed up the healing of any lesion and accelerate physical/muscular recovery after intense exercise. COSMETIC BENEFITS (36) (A) GH and IGF-1 will increase collagen production and give your skin that glow and elasticity that it has lost over the years. The same goes for hair, beard and nails. These will grow faster, healthier and stronger when using Ipamorelin on a regular basis. 37 https://documents-downloader.pages.dev/document 38/94 05/05/2023, 09:27 Documents Downloader OTHER BENEFITS (37) (A) By increasing GH and IGF-1 levels, you can expect CJC-1295 to: - Decrease inflammation. Improve your immune response. Act as an antioxidant. Fight neurodegeneration and improve memory. Improve cardiovascular health. Due to being a Ghrelin agonist, Ipamorelin will increase your appetite. This can be a benefit if you are trying to bulk up, but a serious detriment to your progress if you are trying to lose weight. Administering it before bed tends to solve the issue for most people, but not for everyone. Since the half-life is short, my recommendation is that you play around with the timing of your injections until you find the protocol that works best for you. 38 https://documents-downloader.pages.dev/document 39/94 05/05/2023, 09:27 Documents Downloader UNSTABLE BLOOD GLUCOSE LEVELS (38) (A) Growth Hormone is known for increasing blood sugar levels. When taking Ipamorelin, this is something you have to keep an eye on, especially if you diet is carb-heavy. I recommend taking around 300mg of Berberine before every meal containing a decent amount of carbs (50g+) when cycling CJC. WATER RETENTION (A) Ipamorelin will cause some degree of water retention, which can lead to high blood pressure and in some cases edema. You can mitigate this side-effect by decreasing your carb and sodium intake, eating foods rich in potassium and supplementing with Dandelion Root (500mg / day) or just taking a natural diuretic blend like “Water Out” by Now Foods. OTHER SIDE-EFFECTS (39) (A) Some people report feeling lethargic. Feelings of numbness/tingling in some extremities is also common with anything that increase GH levels. Lethargy is usually resolved by lowering the dose, whereas numbness usually goes away when you implement measures to bring down water retention. 39 https://documents-downloader.pages.dev/document 40/94 05/05/2023, 09:27 Documents Downloader Having chronically elevated GH levels for long periods of time can lead to the growth of certain body parts such as hands, feet, nose and even organs. As mentioned previously, it is normal for users to experience increased appetite on Ipamorelin. Unlike other GH secretagogue that are not as selective, Ipamorelin does NOT increase prolactin levels, so side-effects like gynecomastia, erectile dysfunction and reduced sex drive are, in theory, not possible. CANCEr gROWTH RISK (40) (A) GH and IGF-1 will accelerate the growth of existing cancer cells, so this peptide and any other substance that increases circulating levels of these hormones could be lethal for anyone who has cancer. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 40 https://documents-downloader.pages.dev/document 41/94 05/05/2023, 09:27 Documents Downloader As I said before, Ipamorelin can either be used on its own or stacked with a GHRH analogue like CJC-1295. Forget oral administration, Ipamorelin should be injected (nasal sprays exist but as with most peptides the bioavailability sucks and that makes it expensive). If you do not plan on stacking it with CJC and you want to use it for anti-aging purposes, you can inject once a day, preferably before day. Inject 150-300mcg subcutaneously into your belly fat. If you are just using it to lose fat, you can do the exact same and inject 150 mcg before bed (4 hours after last meal) and then repeat the same when you wake up (followed by 4 hours of fasting). If you do not plan on stacking it with CJC and you want to use it as PED (not just to lose fat), you will have to inject 4 times a day. I recommend injecting 50-75mcg before bed, again when you wake up, again before lunch and again in the late afternoon. As you know, CJC-1295 has a 6-8 day half-life, meaning that a single injection will provide a stable increase in GH and IGF1 levels that will last for days. However, Ipamorelin has a very short half-life. With this in mind, there are two ways that you can stack Ipamorelin and CJC-1295. The first protocol consists in doing one big 1mg Ipamorelin shot per week, and then injecting Ipamorelin “strategically” every single day before bed, in the morning to lose fat or before a workout to boost performance, depending on what 41 https://documents-downloader.pages.dev/document 42/94 05/05/2023, 09:27 Documents Downloader your goals are. If you go for this approach, inject smaller amounts (in the 25-50mcg per shot range). The second protocol consists in doing the same as if you were using Ipamorelin for performance-enhancing benefits (so 4 injections throughout the day) but instead of injecting 5075mcg per shot, you would be injecting 25-50mcg per shot along with 100-125mcg of CJC-1295 per day, injected before bed. Regarding cycle length, there is not a one-size-fits-all answer. If you are using it for healing a specific injury, gaining some muscle or burning fat, I would not exceed the 12 weeks mark. Always rest for at least 4-6 weeks between Ipamorelin (or Ipamorelin + CJC) cycles. P.S: If you choose to use the intranasal spray, follow these instructions but administer 2-3x as much as you would be administering if you were using the injectable form. 42 https://documents-downloader.pages.dev/document 43/94 05/05/2023, 09:27 Documents Downloader GHK-Cu Half-life: <1 hour Dose: 0.5-1mg/day Cycle Length: As needed Legality: LEGAL WADA: Not Banned is a naturally occurring copper peptide that has incredible anti-aging benefits. It was first isolated from blood plasma, but it can also be found in urine and saliva. Despite having no performance-enhancing properties (this is not a PED), GHK-Cu is an excellent anti-inflammatory that can improve immune response, heal wounds faster, increase collagen production, and promote angiogenesis (blood vessel growth). Unlike most peptides in this e-book, GHK-Cu is 100% legal and sold over the counter in cosmetic products, which are what I recommend you use if you want to give this peptide a try. 43 https://documents-downloader.pages.dev/document 44/94 05/05/2023, 09:27 Documents Downloader HEALING (41) (A) Like BPC-157 and TB-500, GHK-Cu has been proven to heal wounds, cuts and burns by inducing angiogenesis, the creation of new blood vessels. There is a limited amount of anecdotal data on the use of injectable GHK-Cu to heal wounds, but the topical formulations are known to work rather well. Furthermore, it has also been shown to have healing effects on joints and ligaments, plus it can increase glutathione levels which makes it a potential tool for the treatment of hepatic (liver) damage. Some data suggests that one of the mechanisms through which GHK-Cu can heal certain tissues is by modulating gene expression. ANTI-INFLAMMATION (42) (A) GHK-Cu decreases inflammation significantly. Not only in the skin, when applied topically, but also throughout the entire body when injected. It is being studied as a potential alternative to corticosteroids for the treatment of inflammatory skin conditions, which goes to show just how effective and miraculous this peptide is. 44 https://documents-downloader.pages.dev/document 45/94 05/05/2023, 09:27 Documents Downloader Corticosteroids are the final solution to inflammatory skin conditions, but they come with a long list of serious sideeffects. A natural, safe peptide like GHK may offer the same benefits without any of the side-effects. COSMETIC BENEFITS (43) (A) Sure, GHK has many positive effects, but when it comes to healing and anti-inflammation, injecting BPC-157 or TB-500 over GHK is simply better. What makes GHK-Cu is how effective it is at improving your looks, no other peptide comes close. Multiple studies have been conducted to analyse the effectiveness of GHK-Cu at improving skin quality, and it has been shown to increase Collagen production significantly, even more so than some retinols, which are usually prescription-only.It has also been studied for its effects on hair growth, and it was found to be comparable to Minoxidil 5%. While the anecdotal data clearly proves that the findings about GHK’s effects on skin quality are true, there just isn’t enough anecdotal evidence to support the claims made about its effectiveness as a hair growth agent, so I personally would not expect GHK-Cu to grow a beard or reverse hair loss like Minoxidil can. By improving collagen synthesis, GHK-Cu can also be effective at fading acne scars and reducing fine lines and wrinkles. It is also worth noting that it can protect the skin from UV radiation. 45 https://documents-downloader.pages.dev/document 46/94 05/05/2023, 09:27 Documents Downloader OTHER BENEFITS (44) (A) These are some of the other positive effects of GHK-Cu: - GHK-Cu has been shown to promote nerve fibre (Axon) regeneration in vitro. - GHK-Cu has been found to help prevent metastasis in colon cancer. - GHK-Cu may have DNA-repairing properties. - GHK-Cu may improve digestive health. - GHK-Cu may ease the symptoms of Chronic Pulmonary disease. Some companies sell a peptide known as PAL-GHK. This peptide and GHK-Cu are essentially identical in terms of benefits and side-effects, so they can be used interchangeably. The data regarding the differences between these two molecules is extremely confusing, but PAL-GHK is believed to be better for transdermal delivery due to it being palmitoylated. Topical GHK-Cu formulations are always dissolved in solvents that enhance its ability to be absorbed through the skin. Another similar peptide is AHK-Cu, which according to scientific data has the same benefits as GHK-Cu, though it is much more effective at increasing hair growth. Unfortunately, finding reliable anecdotal information about PAL-GHK and AHK-Cu is ridiculously hard, so my recommendation is that you stick to GHK-Cu. If you get PALGHK or AHK-Cu, dose them as you would dose GHK-Cu. 46 https://documents-downloader.pages.dev/document 47/94 05/05/2023, 09:27 Documents Downloader RISK OF CANCER GROWTH There is no data to suggest that it can have cancer-growing properties, but if we extrapolate from BPC and TB, which may cause cancer cell growth through angiogenesis, there is a chance that the same would apply to GHK when injected due to its systemic effects. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 47 https://documents-downloader.pages.dev/document 48/94 05/05/2023, 09:27 Documents Downloader As I mentioned earlier, I personally recommend that you use GHK-Cu topically for its cosmetic benefits. You can definitely inject it to reap all of its benefits, but that makes it less practical and it simply is not as effective as BPC-157 or TB500 when it comes to healing injuries. Most companies that carry GHK-Cu as a legal cosmetic product usually sell it as the main ingredient in a serum that contains other ingredients that are also beneficial for the skin. Furthermore, they rarely mention the exact dose of GHK-Cu in their products, so just follow their instructions on how to use it. I personally recommend “Buffet + Copper Peptides 1%” by “The Ordinary”. If you prefer to source it from a research chemical vendor for injectable use, then my recommended protocol would be to inject 500mcg a day before bed for a week, then 1mg daily for the rest of the cycle. There is not a set amount of time that you are supposed to use GHK-Cu for, but if you are using it for its healing properties, I would suggest you stop the cycle once the injury/wound you were treating has healed. If you use the injectable for its cosmetic benefits, simply reduce the daily dose down to 250mcg/day after a month of use, this will be a maintenance dose that you can stay on for months. But again, if you are doing it for the cosmetic benefits, just use a topical formulation. 48 https://documents-downloader.pages.dev/document 49/94 05/05/2023, 09:27 Documents Downloader DSIP Half-life: <1 hour Dose: 100mcg/day Cycle Length: As needed Legality: Research Chem WADA: Not Banned is a neuropeptide that, as the name indicates, induces sleepiness when injected. Neuropeptides are produced by neurons and they act as neurotransmitters. DSIP was first isolated from the cerebral blood of Rabbits in 1977. DSIP is also produced in the human brain and it has also been found in human breast milk, therefore it is a naturally occurring peptide. Even though the main function of DSIP is to induce delta sleep, it has many other benefits that can significantly improve one’s health, well-being and physical performance. 49 https://documents-downloader.pages.dev/document 50/94 05/05/2023, 09:27 Documents Downloader SLEEP (45) (A) The name of this peptide speaks for itself. When injected, it has been shown to induce a deep state of sleep rapidly and effectively. The term “delta” refers to the delta waves that occur during Stage 3 sleep, the deepest sleep phase that we go through every night. During this stage, it is harder for someone or something to wake us up, and evidence shows that it is critical for physical recovery, growth, memory and creativity. By inducing and improving the quality of this particularly important stage of sleep, DSIP can not only improve our quality of life significantly, but it can also have a positive impact on our cognitive performance and our physical development (more gains!). HORMONAL REGULATION (46) (A) Studies have shown that DSIP can increase the secretion of LH, which translates into higher Testosterone levels. But that is not all, it also stimulates the secretion of Growth Hormone and suppresses somatostatin, a peptide hormone that limits how much GH we secrete. Note that a study on women found that DSIP did not significantly increase GH. 50 https://documents-downloader.pages.dev/document 51/94 05/05/2023, 09:27 Documents Downloader It has also been found to decrease adrenocorticotropin levels, a hormone that is produced in response to stress which mediates the production and release of cortisol. This makes DSIP a powerful anti-stress peptide. OTHER BENEFITS (47) (A) Other than improving our health by modulating our sleep, decreasing stress and optimizing our hormonal levels, DSIP has a ton of health benefits that will definitely surprise you… - DSIP may stabilize blood pressure and heart rate. DSIP may ease hypothermia. DSIP may have antioxidant properties. DSIP may have antidepressant properties. DSIP may alleviate symptoms of narcolepsy. DSIP may help fight alcohol and opioid addiction. DSIP may act as a painkiller under some circumstances. DSIP may help prevent certain types of cancer. 51 https://documents-downloader.pages.dev/document 52/94 05/05/2023, 09:27 Documents Downloader No relevant side-effects have been found in scientific studies. Anecdotal reports indicate that DSIP may in fact be side-effect free if used responsibly. It is worth noting that higher concentrations of DSIP have been found in people with Alzheimer’s disease, but it is unlikely to be a causal factor. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 52 https://documents-downloader.pages.dev/document 53/94 05/05/2023, 09:27 Documents Downloader This is one of the least used peptides, primarily due to it being harder to acquire than other research chemicals. For that reason, there is an extremely limited amount of anecdotal information about it, and people’s protocols differ a lot. Based on my research, I would recommend 100mcg subcutaneous injections right before bed. No need to increase the dose overtime, just take 1 week breaks every 4 weeks on to prevent desensitization. This peptide could theoretically be used indefinitely (with the 1-week breaks), but it is not something I would personally recommend because we do not really know what could happen after years of continued use. In my opinion, the best way to use this peptide would be to cycle it for 1-2 months during periods of increased stress, hard work/study and/or irregular sleep patterns. 53 https://documents-downloader.pages.dev/document 54/94 05/05/2023, 09:27 Documents Downloader PT-141 Half-life: 3 hours Dose: 125-250mcg/day Cycle Length: As needed Legality: Prescription/RC WADA: Not Banned is a synthetic analogue of a naturally occurring peptide hormone known as α-MSH. This peptide is a metabolite of Melanotan-II. This compound simply provides the sexual enhancement benefits of MT-II without an increase in melanogenesis. It has been approved by the FDA for the treatment of low sexual desire in women, but it also improves erectile function in men. As a metabolite of Melanotan-II, it has some of the same potential side-effects. Despite that, this is widely considered to be a safe and effective cutting-edge drug for the treatment of a condition that has never had an easy solution: Sexual dysfunction in women. 54 https://documents-downloader.pages.dev/document 55/94 05/05/2023, 09:27 Documents Downloader SEXUAL DESIRE IN WOMEN (48) (A) The data on this is clear: As proven by multiple clinical trials, Bremelanotide can safely and effectively increase sexual desire in women, including those who are postmenopausal. Improvements in sexual satisfaction and orgasms were also common among the participants in the studies. Anecdotal data from women who have used this peptide confirms these findings. SEXUAL FUNCTIoN IN MEN (49) (A) The effects of PT-141 on men have not been studied as extensively as in women, but the data also shows a significant improvement in erectile function. In fact, it was shown to be effective at improving erections in men who do not respond to PDE5 inhibitors like Viagra. Despite being developed as a treatment for women, there is a lot more anecdotal data from men than there is from women. Most men report that unlike Viagra or Cialis, PT-141 causes erections that are hard to manage because they often occur in the absence of sexual stimulation. The half-life of this peptide is short and it is almost always used strategically before sex, so you should not worry about having spontaneous erections in public. 55 https://documents-downloader.pages.dev/document 56/94 05/05/2023, 09:27 Documents Downloader Many men also report increased sexual desire. OTHER BENEFITS (A) As you can see in the profile about Melanotan-II, that peptide has a wide variety of benefits including fat loss and antiinflammatory actions. There is no scientific data to suggest that PT-141 can also have these positive effects, but it would not be unwise to assume that it does. 56 https://documents-downloader.pages.dev/document 57/94 05/05/2023, 09:27 Documents Downloader GENERAL SIDE-EFFECTS (50) (A) Side-effects like nausea and headaches were fairly common in clinical trials, and they are often reported anecdotally as well. The easiest way to prevent (or at least mitigate) this sideeffect is to work your way up from a very tiny dose (More information in the next page). Facial flushing is also common, but it only lasts for a few minutes. Some users have reported that PT-141 darkened their skin after using it daily for months, which is not surprising considering that this peptide is closely related to Melanotan-II. INJECTION-RELATED SIDE-EFFECTS (A) A lot of people do not know how to inject peptides properly which can lead to skin irritation, scar tissue build-up and other annoying but inconsequential side-effects. 57 https://documents-downloader.pages.dev/document 58/94 05/05/2023, 09:27 Documents Downloader Bremelanotide is easy to use. You can opt for intranasal sprays or injections, both administration methods are highly effective, but the injections require a smaller dose, so they are more cost-effective. Inject 125mcg subcutaneously into your lower belly fat, 30-45 minutes before having sexual intercourse. There is no need to cycle this peptide, you can simply use it whenever you need it. If you tolerate 125mcg well, you can increase the dose up to 250mcg per use. If you choose to use it intranasally, follow the same instructions but with twice the dose. 58 https://documents-downloader.pages.dev/document 59/94 05/05/2023, 09:27 Documents Downloader OTHER GHRPs Ipamorelin may be seen as the best Growth HormoneReleasing Peptide, but it is not the only one worth mentioning. are widely available but no longer as popular as they used to be. The reason why I decided not to do a full profile on every single one of these is simple: They are almost identical to each other and to Ipamorelin in terms of benefits and sideeffects. In the following grid I explain the key differences between these GHRPs in comparison to Ipamorelin, so that you can get a good idea of how to use them. IPam. Ghrp-2 Ghrp-6 Hexa. No cortisol increase. Cortisol increase. Cortisol increase. Cortisol increase. 2h half-life. 30 min. half-life. 2.5h half-life. 1h half-life. 150-300mcg/day 600-900mcg/day 400-600mcg/day 200-400mcg/day No prolactin increase. Prolactin increase. Prolactin increase. Prolactin increase. 59 https://documents-downloader.pages.dev/document 60/94 05/05/2023, 09:27 Documents Downloader Again, the benefits and side-effects of all GHRPs are largely the same. Besides the differences listed in the previous grid, it is worth noting that Hexarelin has the best oral bioavailability. All these peptides will increase appetite to varying degrees, but GHRP-6 tends to have the most notable impact on hunger, whereas Ipamorelin will be the most forgiving. In terms of cortisol and prolactin secretion, Ipamorelin takes the prize, but out of the other three GHRP-6 is believed be the least aggressive one. The rest of differences between these peptides come down to half-life. The shorter the half-life, the more intense and shortlived the GH pulse will be. The longer the half-life, the more natural and progressive the GH pulse will be. Some people like to use GHRP-2 or Hexarelin pre-workout because their short half-life provides an immediate increase in GH and IGF-1 levels. If you want to use a GHRP before bed, avoid Hexarelin as it has been shown to have a negative impact on slow-wave sleep. In terms of administration frequency and cycle length, all these peptides can be injected up to 4 times a day, usually after waking up followed by 3-4 hours of fasting, after lunch, pre-workout and before bed. Like Ipamorelin, the rest of GHRPs can also be stacked with CJC-1295 and can be cycled for up to 12 weeks. 60 https://documents-downloader.pages.dev/document 61/94 05/05/2023, 09:27 Documents Downloader OTHER PEPTIDES HUMAN CHORIONIC GONADOTROPIN is a peptide hormone that occurs naturally in pregnant women. In fact, HCG is the molecule that pregnancy tests aim to detect in order to determine whether a woman is pregnant or not. Exogenous HCG is used in mainstream medicine to trigger ovulation in infertile women and to boost fertility in men. It is also used as a cancer marker since some tumours can secrete it. In the context of performance enhancement, HCG is extremely useful because it acts as an analogue of LH (Luteinizing Hormone), making it an excellent ancillary for boosting fertility, keeping our testes full & running during a highly suppressive cycle or simply to kickstart endogenous Testosterone production after the cycle. Unfortunately, HCG is suppressive because it causes endogenous LH levels to drop significantly. For that reason, HCG use for the purpose of PCT is always followed by the use of SERMs, which boost Testosterone levels by increasing endogenous LH, rather than replacing LH like HCG does. Another common concern with HCG is that it can cause serious estrogenic and androgenic side-effects if a high dose is administered. 61 https://documents-downloader.pages.dev/document 62/94 05/05/2023, 09:27 Documents Downloader When used for preserving fertility and testicular function during cycles or on TRT, most men opt for injecting around 500iu twice a week (so every 3.5 days). Using it after a cycle to kickstart Testosterone production (assuming HCG was not used on-cycle) requires 500iu every other day for 2 weeks, followed by 4 weeks of SERM use. KISSPEptiN-10 is an interesting peptide that is starting to gain popularity as an alternative to HCG. Kisspeptins are naturally occurring peptides that play a wide variety of roles, but are primarily responsible for stimulating GnRH (Gonadotropin Releasing Hormone), which consequently causes the stimulation of LH/FSH and an increase in Testosterone levels and spermatogenesis. Kisspeptins can also aid in tumor suppression (they being studied as a potential cancer treatment), reproduction and kidney health, which they improve by stimulating the secretion of Aldosterone, a hormone that regulates blood pressure, sodium and potassium. Kisspeptin-10 is often prescribed by TRT clinics as an ancillary that can help preserve fertility in the presence of exogenous Testosterone. Therefore, it can also be used on-cycle to keep the testicles running and/or post-cycle to help restore endogenous Testosterone levels. 62 https://documents-downloader.pages.dev/document 63/94 05/05/2023, 09:27 Documents Downloader The main selling point of Kisspeptin-10 is that, unlike HCG, it does not cause suppression because it stimulates LH instead of mimicking it. It simply tells the body to produce more LH, so when you come off Kisspeptin-10, you return to baseline instead of having low LH levels. Its side-effects are dose dependent and are primarily estrogenic and androgenic due to this peptide causing high testosterone levels. The fertility protocol that clinics are prescribing is 10iu twice a week (every 3.5 days). There is not much anecdotal information about the use of Kisspeptin-10 to keep testicles working on-cycle or as a PCT, but if I had to guess the ideal dose, I would put it at 10iu twice a week on-cycle and/or 10iu every other day as PCT. Take this info with a grain of salt. INSULIN-LIKE GROWTH FACTOR 1 is a peptide hormone that is essential for development during puberty, anabolism, bone strength, neurological preservation and overall health. I have already mentioned IGF-1 a bunch of times in this ebook, because all GH secretagogues can increase it significantly, but you can also use it as a standalone injectable peptide. The benefits of IGF-1 are many, but bodybuilders use it for its anabolic properties, hyperplasia, fat loss, bone strength, improved sleep, better skin quality, anti-aging and antiinflammation. 63 https://documents-downloader.pages.dev/document 64/94 05/05/2023, 09:27 Documents Downloader Unfortunately, high IGF-1 levels have been linked with cancer, but it is not clear whether IGF-1 actively causes certain types of cancer, or if it simply causes tumours to grow faster (which it does). Injectable IGF-1 generally comes in two “formats IGF-1 LR3 has a long half-life of 20-30 hours, whereas IGF-1 DES has a half-life of approximately 30 minutes. In terms of potency, both variants are very potent, but IGF-1 DES definitely wins. LR3 is usually injected once a day at 50-150mcg/day, same with IGF-1 DES except it should be used right before a workout for optimal results due to its short half-life. Some users claim that using injectable IGF-1 allowed them to get localized gains, meaning that whatever muscle they injected IGF-1 into would experience more growth than the other muscles. On the other hand, you will also find hundreds of users who claim that IGF-1 did nothing for them. Unfortunately, IGF-1 DES and LR3 are two of the most expensive and faked peptides on the market. EPITALON is an anti-aging peptide that works by activating telomerase. It is a synthetic derivative of Epithalamin, a substance that can be found in the pineal gland. Epitalon is one of the rarest and most underrated peptides on the market 64 https://documents-downloader.pages.dev/document 65/94 05/05/2023, 09:27 Documents Downloader (you can hardly find it online) and it was developed by Russian scientists in the late Soviet Union. All studies on Epitalon come from those scientists and most were conducted on animals or cells, which makes the peptide community very sceptical about the purported benefits of this substance. According to the scientific data we have, Epitalon is a powerful antioxidant that contributes to the production of melatonin and superoxide dismutase. This increase in melatonin makes Epitalon an excellent sleep drug that can correct altered circadian rhythms. It was also found to be remarkably effective at increasing the lifespan of rodents, primarily by activating telomerase which contributes to cell division and growth. Additionally, some studies suggest that it can cause apoptosis in cancer cells, making Epitalon a potential anti-cancer drug. A clinical trial on elderly people that lasted for 13 years found that the participants on Epitalon were less likely to die from cardiovascular complications, and a greater percentage of participants on Epitalon “survived” the clinical trial (meaning that the rest were simply too old and they didn’t live for long enough to reach the end of the trial). There is not a lot of anecdotal information on the benefits and side-effects of Epitalon, but the few people I have talked to who have been able to use it claim that it made them feel extremely well-rested. Its long-term effectiveness is what truly matters though, and there is simply no reliable data on that. The recommended Epitalon protocol consists in doing 50mg of Epitalon every 6 months. 10mg every 3 days for a total of 50mg (so roughly 2.5 weeks), twice a year. 65 https://documents-downloader.pages.dev/document 66/94 05/05/2023, 09:27 Documents Downloader HOW TO RECONSTITUTE AND ADMINISTER PEPTIDES 66 https://documents-downloader.pages.dev/document 67/94 05/05/2023, 09:27 Documents Downloader 1. Reconstitution Reconstitution is the process by which we turn the powdered peptide inside a vial into a liquid solution that we can inject. Peptides are reconstituted with BAC (Bacteriostatic) water, a form of bacteria-proof water that contains 0.9% Benzyl Alcohol. Using Sterile Water instead is also possible, but most Peptide vendors just sell BAC water and that is what I recommend you use. To do the reconstitution you will need: - The peptide vial. A vial of BAC water (or Sterile Water). A syringe (needle can be of any size). Alcohol wipes. Step number one is removing the plastic caps from both vials and cleaning both rubber stoppers with alcohol wipes. Once that is done, you can extract BAC water from one vial and inject it into the other. You can use anywhere from 1 to 5ml of BAC water, but given the size of Peptide vials, I personally recommend using 2ml of BAC water per vial. Now take the syringe and look at the measurements on the side. They will either be in millilitres (mL) or in units (I.U). 10 units = 0.1ml, so 2ml equals 200 units. As stated previously, you can use any kind of syringe to do the reconstitution, but never use that same needle to do your first injection. Chances are your syringe will only have room for up to 1ml, so if you decide to use 2ml you will simply have to move 1ml from vial to vial at a time. 67 https://documents-downloader.pages.dev/document 68/94 05/05/2023, 09:27 Documents Downloader This step is quite simple, just stick the needle into the BAC water vial and extract the desired amount (1ml or more, if possible). Now that your syringe is fully loaded, make sure there are no bubbles and proceed to introduce the needle into the peptide vial. Aim the tip of the needle towards either side of the vial and slowly inject the water into the vial, always making sure that the water slides down the walls of the vial before reaching the powder. If you aim the needle directly at the powder and you shoot the water right at it there is a chance that you will damage the peptide and decrease its effectiveness. Repeat this process if your syringe cannot hold as much water as you need/want to use for the reconstitution. Once all the water is inside the vial, do NOT shake it but swirl it gently and let the water do its job at dissolving the powder. It may take a couple of minutes, but the water will always fully dissolve the powder if both agents are pure. Now that the vial is fully reconstituted, the peptide can finally be used. Chances are you are good enough at math to understand the mg/ml concentration of a vial after reconstitution, but here is a quick recap: For example, if your vial of X peptide contains 5mg of active ingredient and you reconstitute it with 2ml of BAC water, the approximate amount of active ingredient per ml will be of 2.5mg per ml. With all due respect, if you have a hard time understanding this… Peptides may not be for you. 68 https://documents-downloader.pages.dev/document 69/94 05/05/2023, 09:27 Documents Downloader 2. ADMINISTRATION Time to inject! Now, except for BPC-157 all the peptides I have covered in this e-book have systemic effects, meaning that regardless of where you inject them, they will exert their effects throughout your entire body. BPC-157 works best when injected locally, meaning that you must inject it as close to the area you are trying to treat as possible. Most systemic peptides are injected into lower belly fat, but all peptide injections are executed subcutaneously, meaning that the needle should not reach muscle tissue, bone or any blood vessels. The best way to inject subcutaneously is to pinch some skin with abundant fat underneath and introducing the needle in such a way that you do not go past the layer of fat that you wish to inject into. You will need: - The peptide vial. - Alcohol wipes. - Brand new insulin needle (I recommend using 31G needles, but you can go as low as 28G. In terms of length go for 8 to 12mm). Step number one is simple: Figure out exactly how much liquid you are going to inject. In the previous section of this chapter, I covered how to understand mg/ml concentrations. If we take that example again (2.5mg/ml) and you want to inject 500mcg, the amount of liquid you need to inject is of approximately 0.2ml (1000mcg = 1mg) or 20 units. If you want to inject 250mcg, you will need 0.1ml or 10 units, and so on and so forth. 69 https://documents-downloader.pages.dev/document 70/94 05/05/2023, 09:27 Documents Downloader The next step consists of cleaning the rubber stopper on the vial with an alcohol wipe and gently introducing the needle into the vial. Turn the vial + needle upside down, and slowly pull out the desired amount (0.2ml if we take the previous example) while making sure that there are no major bubbles or air gaps in-between. Chances are there will be some small bubbles anyway, but you can get rid of them by pointing the needle upwards and gently tapping the syringe until the bubbles move to the top, allowing you to release them by carefully pressing the plunger. If you are unable to get rid of them, you can simply proceed with the injection. Injecting tiny bubbles subcutaneously is not harmful. Now that your syringe is loaded and ready to go, you have to prepare the injection site. To do so, remove any clothes that might get in the way of your shot, clean the area you wish to inject into with an alcohol wipe and let it dry. Time to pin. Pinch the skin and fat that you wish to inject into with two fingers and use the other hand to handle the syringe. You can either enter the needle at a 45 or a 90-degree angle, I personally find the 45-degree angle to be slightly less painful. Once you have penetrated the first layer of the skin, you can gently introduce the needle and slowly press the plunger to inject the peptide into your subcutaneous fat. Carefully remove the needle (dispose of it accordingly) and massage the injection site with by applying pressure with an alcohol wipe in a circular motion. Congratulations, you survived your first injection! 70 https://documents-downloader.pages.dev/document 71/94 05/05/2023, 09:27 Documents Downloader 3. OTHER TIPS If you are administering BPC-157 you might want to inject subcutaneously into areas that are harder to reach than your lower belly. For example, if you want to heal your wrist you might have to inject into your forearm with the help of your girl or a friend, same goes for the lower back, etc… Be imaginative and get the help of someone else is necessary. Also keep in mind that your bodyfat percentage can make a big difference with regards to where you can inject and where you cannot. A chubby person can easily grab enough fat around their wrist to inject directly into it, whereas a lean bodybuilder would have to inject into the forearm because injecting into his wrist could be risky. With BPC-157, every time you need to treat a joint or a ligament simply inject subcutaneously into the nearest part of your body with a decent amount of fat. In terms of what needles to use for injecting peptides, I previously recommended 31G insulin needles with an 812mm needle length, but almost any kind of needle can be used to inject subcutaneously. I simply recommend these because they are cheap and painless if the shot is executed properly. This is what insulin needles look like: 71 https://documents-downloader.pages.dev/document 72/94 05/05/2023, 09:27 Documents Downloader SAMPLE CYCLE/PROTOCOL LAY OUTS 72 https://documents-downloader.pages.dev/document 73/94 05/05/2023, 09:27 Documents Downloader INJURY RECOVERY PROTOCOL WK1 Wk2 Wk3… Wk4 Wk5 BPC-157 TB-500 This protocol is ideal for men and women who need to recover from any kind of injury in record time. Fractured bones, stiff joints, torn ligaments, wounds, burn, etc… These two stpeptides will take care of it. Inject 500mcg (0.5mg) of BPC157 every single day and 2mg of TB-500 every other day until your injury has been healed, then cut the dose by half and keep going for a couple of weeks to consolidate the recovery process. In this example the total length of the cycle is 5 weeks, with the injury being healed by week 3. The severity of your injury will determine the length of the cycle. PERFORMANCE AND MOBILITY PROTOCOL WK1 Wk2 Wk3 Wk4 Wk5… TB-500 Simple cycle for athletes who want to get an edge in their sport by improving their mobility, flexibility and recovery times without compromising their health. 73 https://documents-downloader.pages.dev/document 74/94 05/05/2023, 09:27 Documents Downloader “IGF-1 TO THE MOON” PROTOCOL WK1 Wk2 Wk3 Wk4 Wk5… CJC-1295 IPAMORELIN Excellent for bulking up or preserving muscle mass while burning fat. Do a single 1mg shot of CJC-1295 per week (Sunday before bed, for example) and then inject up to 100mcg (0.1mg) of Ipamorelin daily. Do not inject the 100mcg of Ipamorelin at once, spread out the dose between 2 to 4 shots a day. Before bed, as soon as you wake up, before a workout, etc… If pinning 2-4x a day is not your thing, you can simply take 10mg of MK-677 a day to emulate the effects of Ipamorelin. This cycle can last for up to 12 weeks. “FAT-BE-GONE” PROTOCOL WK1 Wk2 Wk3 Wk4 Wk5… frag. Simple Frag. 176-191 protocol for fat loss. 250mcg before bed, 3-4 hours after dinner. Then another 250mcg upon waking up followed by 3-4 hours of fasting. Take 7-10 days off every 20 days on and repeat this process for as long as you need to keep losing fat. 74 https://documents-downloader.pages.dev/document 75/94 05/05/2023, 09:27 Documents Downloader “PERFECT TAN” PROTOCOL WK1 Wk2 Wk3 Wk4 Wk5… MT-II This is the ideal protocol for getting a perfect tan without experiencing the nasty side-effects of Melanotan-II. Start by injecting 75mcg EOD, 30 minutes before sunbathing/tanning bed and gradually increase the dose as indicated in the table. Once you have reached your ideal tan, you can start injecting the same dose E5D (every 5 days) instead of EOD. In this example we would have reached our ideal tan at week 4, but it could happen much sooner and at a lower dose or much later at a higher dose. The point is to gradually increase the dose until we reach out desired tan and then use that same dose E5D to maintain that tan. 75 https://documents-downloader.pages.dev/document 76/94 05/05/2023, 09:27 Documents Downloader FREQUENTLY ASKED QUESTIONS 76 https://documents-downloader.pages.dev/document 77/94 05/05/2023, 09:27 Documents Downloader “CAN I USE (X) PEPTiDE ORALLY?” Everyone wants the easy way out and no one wants to inject every single day. Most peptides do not offer enough oral bioavailability to justify this route of administration, but there are some exceptions. BPC-157 can be used orally, it will have a major impact on gut health and mild systemic healing effects. TB-500 can also be used orally but according to anecdotal reports the results are not exceptionally good. I really want to stress that if you are only going to be using peptides orally, you are better off saving that money and not using anything at all. The only exception to that rule would be oral BPC-157 for the purpose of healing the gut. “CAN I USE (X) PEPTiDE INTRANSAllY?” Melanotan-II, CJC-1295 and the GHRPs can be used intranasally for acceptable results, but you will have to use 2x the dose and that makes such cycles awfully expensive. The rest of peptides in this e-book are not worth using intranasally, though they might still have some positive effects. “I’M young, CAN I USE pepTideS?” Peptides are commonly referred to as “anti-aging” compounds. With that being said, age is only relevant when 77 https://documents-downloader.pages.dev/document 78/94 05/05/2023, 09:27 Documents Downloader using certain peptides. For instance, a 49-year-old man will benefit more from CJC-1295 or a GHRP like Ipamorelin than a young 22-year-old guy at his prime, but both can equally benefit from BPC-157 if they are injured. However, I personally believe that teenagers should avoid anything that increases their GH levels. Their GH levels are already good enough, and using a GHRH or GHRP could accelerate and maximize the growth of certain body parts in a negative way. By the same token, anyone who is at risk of getting cancer (people with previous cancer history or old people) should be really careful with BPC-157, GHK-Cu, TB-500 and any GHRH/GHRP. “HOW LONG DO PEPTIDE VIALS LAST FOR?” 30 days after reconstitution if stored properly. Yes, peptides lose potency very rapidly and most become entirely useless 30 days after reconstitution, even if stored in a refrigerator. If you do not store a reconstituted vial properly, its efficacy will evaporate in a matter of days. “CAN I TRAVEL WITH PEPTIDES?” Travelling with a bunch of vials and needles is a bit risky when you do not have the prescriptions to justify their use. I would not take the risk unless travelling with an intranasal spray. 78 https://documents-downloader.pages.dev/document 79/94 05/05/2023, 09:27 Documents Downloader Sure, you can simply travel with the vials and get the needles elsewhere but knowing how strict airport controls are I would not be surprised if the shape of a vial through an X-Ray machine raised an eyebrow. “WHaT NEEDLES SHOULD I USE?” As I explained in the “How to Reconstitute and Administer Peptides” chapter, I personally recommend using 31G insulin needles with a needle length of 8 to 12mm. Pretty much any kind of needle can be used for subcutaneous injections, but the ones I recommend cause the least amount of pain while having the ideal length for executing subcutaneous injections. 79 https://documents-downloader.pages.dev/document 80/94 05/05/2023, 09:27 Documents Downloader You can get insulin needles and alcohol wipes at your local pharmacy, no prescription. Alternatively, you can get them online from a medical supply website like allegromedical.com. As mentioned in the GHK-Cu profile, I recommend getting a “Buffet + Copper Peptides 1%” from The Ordinary. 80 https://documents-downloader.pages.dev/document 81/94 05/05/2023, 09:27 Documents Downloader If you have enjoyed this e-book, you should definitely check out my other e-books: - THE SARM HANDBOOK - The Ultimate guide to male enhancement - A Quick Guide to Pro-HORMONES If you want to want to learn about Steroids, check out the best book on the subject ever written, “Anabolics” by Dr. Llewellyn. - ANABOLICS 11th edition by DR. LLEWELLYN And finally, if you want to dive deeper into peptides, take a look at the scientific studies that you will find in the following pages! 81 https://documents-downloader.pages.dev/document 82/94 05/05/2023, 09:27 Documents Downloader BPC-157 1. HEALING OF WOUNDS AND BURNS ▪ https://pubmed.ncbi.nlm.nih.gov/11718984/ ▪ https://www.sciencedirect.com/science/article/abs/pii/S0305417904003158 ▪ https://www.sciencedirect.com/science/article/abs/pii/S0305417903000044 ▪ https://pubmed.ncbi.nlm.nih.gov/16785777/ ▪ https://www.sciencedirect.com/science/article/abs/pii/S0928425797894806 2. HEALING OF BONES AND TENDONS ▪ https://pubmed.ncbi.nlm.nih.gov/10071911/ ▪ https://onlinelibrary.wiley.com/doi/abs/10.1002/jor.20096 ▪ https://link.springer.com/article/10.1007/s00011-007-7056-8 ▪ https://onlinelibrary.wiley.com/doi/abs/10.1016/S0736-0266(03)00110-4 3. HEALING OF MUSCLES ▪ https://pubmed.ncbi.nlm.nih.gov/16609979/ ▪ https://pubmed.ncbi.nlm.nih.gov/18668315/ ▪ https://pubmed.ncbi.nlm.nih.gov/20190676/ 4. NEUROPROTECTION ▪ https://pubmed.ncbi.nlm.nih.gov/19931318/ ▪ https://pubmed.ncbi.nlm.nih.gov/19903499/ ▪ https://www.sciencedirect.com/science/article/abs/pii/S0014299999004860 https://pubmed.ncbi.nlm.nih.gov/10791689/ ▪ 5. IMPROVED DIGESTIVE HEALTH ▪ https://www.sciencedirect.com/science/article/abs/pii/S0014299999004860 ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717094/ ▪ https://pubmed.ncbi.nlm.nih.gov/21548867/ ▪ https://pubmed.ncbi.nlm.nih.gov/11292068/ https://pubmed.ncbi.nlm.nih.gov/7904712/ ▪ 6. OTHER BENEFITS 82 https://documents-downloader.pages.dev/document 83/94 05/05/2023, 09:27 Documents Downloader ▪ https://pubmed.ncbi.nlm.nih.gov/11978191/ ▪ https://www.semanticscholar.org/paper/The-effect-of-pentadecapeptide-BPC-157on-direct-Sikiric-Gyires/ef4ce1b1c5642c2ab80b9272203edc434b5386a8 ▪ https://www.sciencedirect.com/science/article/abs/pii/S0014299997010339 ▪ https://pubmed.ncbi.nlm.nih.gov/2198051/ 7. CANCER GROWTH ▪ https://pubmed.ncbi.nlm.nih.gov/23782145/ TB-500 8. HEALING OF WOUNDS AND BURNS ▪ https://pubmed.ncbi.nlm.nih.gov/20536453/ ▪ https://pubmed.ncbi.nlm.nih.gov/22074294/ ▪ https://pubmed.ncbi.nlm.nih.gov/20536467/ ▪ https://pubmed.ncbi.nlm.nih.gov/25230158/ ▪ https://pubmed.ncbi.nlm.nih.gov/27450738/ ▪ https://www.spandidos-publications.com/10.3892/ijmm.2020.4701 9. HEALING OF BONES AND TENDONS ▪ https://pubmed.ncbi.nlm.nih.gov/23523891/ ▪ https://pubmed.ncbi.nlm.nih.gov/25042765/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720371/ 10. MUSCLE GROWTH ▪ 11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813286/ NEUROPROTECTION ▪ https://pubmed.ncbi.nlm.nih.gov/31877278/ ▪ https://pubmed.ncbi.nlm.nih.gov/29873258/ 12. OTHER BENEFITS ▪ https://pubmed.ncbi.nlm.nih.gov/30063857/ ▪ https://pubmed.ncbi.nlm.nih.gov/22217673/ ▪ https://pubmed.ncbi.nlm.nih.gov/27575556/ ▪ https://pubmed.ncbi.nlm.nih.gov/29063072/ ▪ https://pubmed.ncbi.nlm.nih.gov/26006229/ https://pubmed.ncbi.nlm.nih.gov/27450733/ ▪ 83 https://documents-downloader.pages.dev/document 84/94 05/05/2023, 09:27 Documents Downloader 13. CANCER RISK ▪ https://pubmed.ncbi.nlm.nih.gov/27521796/ ▪ https://pubmed.ncbi.nlm.nih.gov/31048733/ ▪ https://pubmed.ncbi.nlm.nih.gov/18094619/ ▪ https://pubmed.ncbi.nlm.nih.gov/22233609/ ▪ https://pubmed.ncbi.nlm.nih.gov/27744656/ ▪ https://pubmed.ncbi.nlm.nih.gov/17495241/ ▪ https://pubmed.ncbi.nlm.nih.gov/21621326/ MELANOTAN-II 14. TANNING ▪ https://pubmed.ncbi.nlm.nih.gov/8637402/ ▪ https://pubmed.ncbi.nlm.nih.gov/11045725/ ▪ https://pubmed.ncbi.nlm.nih.gov/20545686/ ▪ https://pubmed.ncbi.nlm.nih.gov/33245851/ 15. IMPROVED SEXUAL FUNCTION ▪ https://pubmed.ncbi.nlm.nih.gov/23131503/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694735/ ▪ https://pubmed.ncbi.nlm.nih.gov/11035391/ ▪ https://pubmed.ncbi.nlm.nih.gov/12172010/ ▪ https://pubmed.ncbi.nlm.nih.gov/16839319/ 16. FAT LOSS ▪ https://pubmed.ncbi.nlm.nih.gov/29649791/ ▪ https://pubmed.ncbi.nlm.nih.gov/11581309/ ▪ https://pubmed.ncbi.nlm.nih.gov/25549049/ ▪ https://pubmed.ncbi.nlm.nih.gov/10662844/ 17. ANTI-INFLAMMATION ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936413/ ▪ https://pubmed.ncbi.nlm.nih.gov/9045742/ ▪ https://pubmed.ncbi.nlm.nih.gov/23940690/ ▪ https://www.hindawi.com/journals/bmri/2014/874610/ 84 https://documents-downloader.pages.dev/document 85/94 05/05/2023, 09:27 Documents Downloader 18. OTHER BENEFITS ▪ https://pubmed.ncbi.nlm.nih.gov/11581309/ ▪ https://pubmed.ncbi.nlm.nih.gov/30629642/ ▪ https://pubmed.ncbi.nlm.nih.gov/33332767/ ▪ https://pubmed.ncbi.nlm.nih.gov/28009464/ ▪ https://pubmed.ncbi.nlm.nih.gov/12591111/ 19. SKIN-RELATED SIDE-EFFECTS ▪ https://pubmed.ncbi.nlm.nih.gov/24355990/ ▪ https://pubmed.ncbi.nlm.nih.gov/30796078/ ▪ https://pubmed.ncbi.nlm.nih.gov/33460908/ 20. GENERAL SIDE-EFFECTS ▪ https://pubmed.ncbi.nlm.nih.gov/14643840/ ▪ https://pubmed.ncbi.nlm.nih.gov/15862523/ ▪ https://pubmed.ncbi.nlm.nih.gov/20080115/ ▪ https://pubmed.ncbi.nlm.nih.gov/17052748/ ▪ https://pubmed.ncbi.nlm.nih.gov/12915762/ ▪ https://pubmed.ncbi.nlm.nih.gov/10904142/ ▪ https://pubmed.ncbi.nlm.nih.gov/31953620/ ▪ https://pubmed.ncbi.nlm.nih.gov/23121206/ FRAG. 176-191 / AOD-9604 21. FAT LOSS ▪ https://pubmed.ncbi.nlm.nih.gov/11713213/ ▪ https://pubmed.ncbi.nlm.nih.gov/25208511/ ▪ https://pubmed.ncbi.nlm.nih.gov/11713213/ ▪ https://pubmed.ncbi.nlm.nih.gov/11146367/ ▪ https://www.biospace.com/article/releases/metabolic-pharmaceuticals-sobesity-trial-update-first-100-subjects-complete-the-phase-2b-trial-ofaod9604-/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584306/ ▪ https://pubmed.ncbi.nlm.nih.gov/10950816/ 22. GENERAL SIDE-EFFECTS ▪ https://pubmed.ncbi.nlm.nih.gov/11673763/ 85 https://documents-downloader.pages.dev/document 86/94 05/05/2023, 09:27 Documents Downloader ▪ https://pubmed.ncbi.nlm.nih.gov/645904/ ▪ https://www.jofem.org/index.php/jofem/article/view/157 ▪ https://pubmed.ncbi.nlm.nih.gov/11146367/ CJC-1295 23. GAINS IN LEAN MUSCLE MASS ▪ https://pubmed.ncbi.nlm.nih.gov/16352683/ ▪ https://pubmed.ncbi.nlm.nih.gov/17018654/ ▪ https://pubmed.ncbi.nlm.nih.gov/12435897/ ▪ https://pubmed.ncbi.nlm.nih.gov/31491959/ ▪ https://pubmed.ncbi.nlm.nih.gov/10984262/ ▪ https://pubmed.ncbi.nlm.nih.gov/30862132/ ▪ https://pubmed.ncbi.nlm.nih.gov/29172848/ ▪ https://pubmed.ncbi.nlm.nih.gov/17354613/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2439518/ 24. FAT LOSS ▪ https://pubmed.ncbi.nlm.nih.gov/10352397/ ▪ https://pubmed.ncbi.nlm.nih.gov/8300043/ ▪ https://academic.oup.com/jcem/article/90/3/1466/2836752 ▪ https://pubmed.ncbi.nlm.nih.gov/7511202/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117996/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453052/ ▪ https://pubmed.ncbi.nlm.nih.gov/11086655 25. ANTI-AGING ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305861/ ▪ https://pubmed.ncbi.nlm.nih.gov/18477550/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3455269/ ▪ https://pubmed.ncbi.nlm.nih.gov/12652183/ ▪ https://pubmed.ncbi.nlm.nih.gov/29921922/ 26. FASTER HEALING ▪ https://pubmed.ncbi.nlm.nih.gov/10984252/ ▪ https://pubmed.ncbi.nlm.nih.gov/25903440/ ▪ https://pubmed.ncbi.nlm.nih.gov/17309692/ 86 https://documents-downloader.pages.dev/document 87/94 05/05/2023, 09:27 Documents Downloader ▪ https://pubmed.ncbi.nlm.nih.gov/11733094/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851714/ ▪ https://www.sciencedirect.com/science/article/pii/S0022202X15355342 ▪ https://pubmed.ncbi.nlm.nih.gov/24604317/ ▪ https://pubmed.ncbi.nlm.nih.gov/20452307/ ▪ https://pubmed.ncbi.nlm.nih.gov/17386107/ ▪ https://pubmed.ncbi.nlm.nih.gov/10770189/ 27. COSMETIC BENEFITS ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939720/ ▪ https://pubmed.ncbi.nlm.nih.gov/30660669/ ▪ https://pubmed.ncbi.nlm.nih.gov/22281905/ ▪ https://pubmed.ncbi.nlm.nih.gov/19933753/ ▪ https://pubmed.ncbi.nlm.nih.gov/2728814/ 28. OTHER BENEFITS ▪ https://pubmed.ncbi.nlm.nih.gov/29143180/ ▪ https://pubmed.ncbi.nlm.nih.gov/19075233/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590220/ ▪ https://pubmed.ncbi.nlm.nih.gov/23602740/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417471 ▪ https://pubmed.ncbi.nlm.nih.gov/10896637/ ▪ https://pubmed.ncbi.nlm.nih.gov/16444180/ 29. UNSTABLE BLOOD GLUCOSE LEVELS ▪ https://pubmed.ncbi.nlm.nih.gov/1806481/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642081/ ▪ https://pubmed.ncbi.nlm.nih.gov/11945115/ 30. OTHER SIDE-EFFECTS ▪ https://pubmed.ncbi.nlm.nih.gov/14974923/ ▪ https://pubmed.ncbi.nlm.nih.gov/10599729/ ▪ https://pubmed.ncbi.nlm.nih.gov/15069389/ 31. CANCER GROWTH RISK ▪ https://www.sciencedirect.com/science/article/abs/pii/S1096637400901710 ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061931/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603614/ 87 https://documents-downloader.pages.dev/document 88/94 05/05/2023, 09:27 Documents Downloader ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119990/ ▪ https://www.ceu.ox.ac.uk/news/study-of-almost-400-000-confirms-thathigher-blood-levels-of-igf-1-are-a-risk-factor-for-several-types-of-cancer IPAMORELIN 32. GAINS IN LEAN MUSCLE MASS ▪ https://pubmed.ncbi.nlm.nih.gov/10496658/ ▪ https://pubmed.ncbi.nlm.nih.gov/12435897/ ▪ https://pubmed.ncbi.nlm.nih.gov/31491959/ ▪ https://pubmed.ncbi.nlm.nih.gov/10984262/ ▪ https://pubmed.ncbi.nlm.nih.gov/30862132/ ▪ https://pubmed.ncbi.nlm.nih.gov/29172848/ ▪ https://pubmed.ncbi.nlm.nih.gov/17354613/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2439518/ 33. FAT LOSS ▪ https://pubmed.ncbi.nlm.nih.gov/10352397/ ▪ https://pubmed.ncbi.nlm.nih.gov/8300043/ ▪ https://academic.oup.com/jcem/article/90/3/1466/2836752 ▪ https://pubmed.ncbi.nlm.nih.gov/7511202/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117996/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453052/ ▪ https://pubmed.ncbi.nlm.nih.gov/11086655 34. ANTI-AGING ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305861/ ▪ https://pubmed.ncbi.nlm.nih.gov/18477550/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3455269/ ▪ https://pubmed.ncbi.nlm.nih.gov/12652183/ ▪ https://pubmed.ncbi.nlm.nih.gov/29921922/ 35. FASTER HEALING ▪ https://pubmed.ncbi.nlm.nih.gov/10984252/ ▪ https://pubmed.ncbi.nlm.nih.gov/25903440/ ▪ https://pubmed.ncbi.nlm.nih.gov/17309692/ ▪ https://pubmed.ncbi.nlm.nih.gov/11733094/ 88 https://documents-downloader.pages.dev/document 89/94 05/05/2023, 09:27 Documents Downloader ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851714/ ▪ https://www.sciencedirect.com/science/article/pii/S0022202X15355342 ▪ https://pubmed.ncbi.nlm.nih.gov/24604317/ ▪ https://pubmed.ncbi.nlm.nih.gov/20452307/ ▪ https://pubmed.ncbi.nlm.nih.gov/17386107/ ▪ https://pubmed.ncbi.nlm.nih.gov/10770189/ 36. COSMETIC BENEFITS ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939720/ ▪ https://pubmed.ncbi.nlm.nih.gov/30660669/ ▪ https://pubmed.ncbi.nlm.nih.gov/22281905/ ▪ https://pubmed.ncbi.nlm.nih.gov/19933753/ ▪ https://pubmed.ncbi.nlm.nih.gov/2728814/ 37. OTHER BENEFITS ▪ https://pubmed.ncbi.nlm.nih.gov/29143180/ ▪ https://pubmed.ncbi.nlm.nih.gov/19075233/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590220/ ▪ https://pubmed.ncbi.nlm.nih.gov/23602740/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417471 ▪ https://pubmed.ncbi.nlm.nih.gov/10896637/ ▪ https://pubmed.ncbi.nlm.nih.gov/16444180/ 38. UNSTABLE BLOOD GLUCOSE LEVELS ▪ https://pubmed.ncbi.nlm.nih.gov/1806481/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642081/ ▪ https://pubmed.ncbi.nlm.nih.gov/11945115/ 39. OTHER SIDE-EFFECTS ▪ https://pubmed.ncbi.nlm.nih.gov/14974923/ ▪ https://pubmed.ncbi.nlm.nih.gov/10599729/ ▪ https://pubmed.ncbi.nlm.nih.gov/15069389/ 40. CANCER GROWTH RISK ▪ https://www.sciencedirect.com/science/article/abs/pii/S1096637400901710 ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061931/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603614/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119990/ 89 https://documents-downloader.pages.dev/document 90/94 05/05/2023, 09:27 Documents Downloader ▪ https://www.ceu.ox.ac.uk/news/study-of-almost-400-000-confirms-thathigher-blood-levels-of-igf-1-are-a-risk-factor-for-several-types-of-cancer GHK-Cu 41. HEALING ▪ https://pubmed.ncbi.nlm.nih.gov/18644225/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/ ▪ https://pubmed.ncbi.nlm.nih.gov/28370978/ 42. ANTI-INFLAMMATION ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295439/ ▪ https://www.sciencedirect.com/science/article/abs/pii/S0024320519310677 43. COSMETIC BENEFITS ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/ ▪ https://www.longdom.org/open-access/effects-of-ghkcu-on-mmp-and-timpexpression-collagen-and-elastin-production-and-facial-wrinkle-parameters2329-8847-1000166.pdf ▪ https://www.researchgate.net/publication/324724012_Skin_Regenerative_an d_Anti-Cancer_Actions_of_Copper_Peptides ▪ https://pubmed.ncbi.nlm.nih.gov/26236730/ 44. OTHER BENEFITS ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/ ▪ https://www.researchgate.net/publication/324724012_Skin_Regenerative_an d_Anti-Cancer_Actions_of_Copper_Peptides ▪ https://www.hindawi.com/journals/bmri/2014/151479/ ▪ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180391/ ▪ https://www.researchgate.net/publication/225184808_The_Human_Tripeptid e_GHKCu_in_Prevention_of_Oxidative_Stress_and_Degenerative_Conditions_of_Agi ng_Implications_for_Cognitive_Health ▪ https://pubmed.ncbi.nlm.nih.gov/29986520/ ▪ https://pubmed.ncbi.nlm.nih.gov/27517151/ DELTA SLEEP-INDUCING PEPTIDE 90 https://documents-downloader.pages.dev/document 91/94 05/05/2023, 09:27 Documents Downloader 45. SLEEP ▪ https://pubmed.ncbi.nlm.nih.gov/16539679/ ▪ https://pubmed.ncbi.nlm.nih.gov/3550726/ ▪ https://pubmed.ncbi.nlm.nih.gov/3286557/ ▪ https://pubmed.ncbi.nlm.nih.gov/6391925/ ▪ https://pubmed.ncbi.nlm.nih.gov/6145137/ ▪ https://pubmed.ncbi.nlm.nih.gov/3758119/ ▪ https://pubmed.ncbi.nlm.nih.gov/30107169/ ▪ https://pubmed.ncbi.nlm.nih.gov/3368469/ 46. HORMONAL REGULATION ▪ https://pubmed.ncbi.nlm.nih.gov/3121137/ ▪ https://pubmed.ncbi.nlm.nih.gov/3550343/ ▪ https://pubmed.ncbi.nlm.nih.gov/2046856/ ▪ https://pubmed.ncbi.nlm.nih.gov/3368469/ ▪ https://pubmed.ncbi.nlm.nih.gov/3575154/ ▪ https://pubmed.ncbi.nlm.nih.gov/8475226/ ▪ https://pubmed.ncbi.nlm.nih.gov/7777652/ ▪ https://pubmed.ncbi.nlm.nih.gov/7698722/ ▪ https://pubmed.ncbi.nlm.nih.gov/8597403/ 47. OTHER BENEFITS ▪ https://www.sciencedirect.com/science/article/abs/pii/S0047637403000824? via%3Dihub ▪ https://www.tandfonline.com/doi/abs/10.3109/08039488509101959 ▪ https://www.tandfonline.com/doi/abs/10.3109/08039488809103215 ▪ https://www.sciencedirect.com/science/article/abs/pii/0014299988905109?vi a%3Dihub ▪ https://www.sciencedirect.com/science/article/abs/pii/S0196978103000408? via%3Dihub PT-141 48. SEXUAL DESIRE IN WOMEN ▪ https://pubmed.ncbi.nlm.nih.gov/31599840/ ▪ https://pubmed.ncbi.nlm.nih.gov/31893927/ ▪ https://pubmed.ncbi.nlm.nih.gov/27181790/ ▪ https://pubmed.ncbi.nlm.nih.gov/31599847/ 91 https://documents-downloader.pages.dev/document 92/94 05/05/2023, 09:27 Documents Downloader ▪ https://pubmed.ncbi.nlm.nih.gov/31277966/ ▪ https://pubmed.ncbi.nlm.nih.gov/17958619/ ▪ https://pubmed.ncbi.nlm.nih.gov/27751477/ 49. SEXUAL FUNCTION IN MEN ▪ https://pubmed.ncbi.nlm.nih.gov/18206919/ ▪ https://pubmed.ncbi.nlm.nih.gov/28189361/ ▪ https://pubmed.ncbi.nlm.nih.gov/12851303/ 50. GENERAL SIDE-EFFECTS ▪ https://pubmed.ncbi.nlm.nih.gov/31599840/ ▪ https://pubmed.ncbi.nlm.nih.gov/31599847/ 92 https://documents-downloader.pages.dev/document 93/94 05/05/2023, 09:27 Documents Downloader 93 https://documents-downloader.pages.dev/document 94/94
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