Bio 161 Penn State Exam 1 Verified question and answer [2025/2026] Anatomy - Ans →Structure of the human body Physiology - Ans →Function of the human body Homeostasis - Ans →Adapt to external variables, Temperature, pH, Blood volume, Sugar levels Negative Feedback Loop - Ans →Body senses change and reacts to negate or reverse the condition Hormone - Ans →Chemical messenger Positive Feedback Loop - Ans →Cycle in which an initial change leads to a greater change, Self-amplifying, rapid change Atom - Ans →Subatomic particles- protons, neutrons, electrons Element - Ans →identified by the number of protons Neutral Atom - Ans →Same number of protons and electrons Ion - Ans →Atoms that have an uneven number of protons and electrons Cation - Ans →Positive charge, give up electrons easily Anion - Ans →Negative charge, accept electrons easily Ionic Bond - Ans →Transfer of electrons Covalent Bond - Ans →Two atoms share electrons Action potentials - Ans →commnunication Molecules - Ans →multiple atoms held together Polar Molecule - Ans →difference of charge at both ends of the molecule Hydrogen Bonds - Ans →attraction between polar molecules Monomer - Ans →single molecular unit of a polymer Polymer - Ans →molecule containing many repeating monomers Carbohydrate Monomers - Ans →Glucose (Blood sugar), Fructose Carbohydrate Polymer - Ans →Glycogen, Cellulose, Starch Carbohydrate - Ans →Provide cellular fuel, enzymes are used to break down sugar in the process of cellular respiration to release ATP Glycogen - Ans →stored carbs in humans Phospholipids - Ans →Cell membrane- Polar hydrophillic Phosphate head, 2 nonpolar hydrophobic fatty acid tails (carbon + hydrogen) Hydrophobic - Ans →hates water Hydrophillic - Ans →loves water Triglycerides - Ans →Energy storage, Insulation, 3 fatty acids and 1 glycerol Saturated fatty acids - Ans →Single bond, as many hydrogens as possible, Meat/dairy, Cardiovascular disease Unsaturated fatty acids - Ans →double or triple bonds, could add a hydrogen or two, plant oils, fish, avocados, omega fatty acids Steroids - Ans →nonpolar, flat or circular, often hormones Proteins - Ans →polymers of amino acid monomers, Primary Structure - Ans →Sequence of amino acids, fold to make final protein shape (Primary structure- Secondary structure- Tertiary structure- Quaternary structure) Nucleic Acids - Ans →DNA polymer consists of 4 different nucleotides Heredity - Ans →genes, genetic blueprint, DNA RNA - Ans →protein synthesis (Gene) Gene expression - Ans →making proteins from our DNA Transcription - Ans →makes a working copy of the gene (RNA) Translation - Ans →Translate the nucleotides to amino acids ATP - Ans →immediate energy, breakdown glucose, 3 phosphates Endoplasmic Reticulum - Ans →Made of lipids, protein translation via ribosomes Ribosomes - Ans →Organelles made of proteins and RNA, found on ER and cytoplasm Golgi Body - Ans →Processes and packages proteins for transport (post office of cell) Cytoskeleton - Ans →important for cell Structure, made of proteins, transports material within the cell Actin - Ans →Cytoskeleton proteins, muscle contraction Mitochondria - Ans →Produce ATP, own DNA (inherited from mother) Cytoplasm - Ans →Fluid within the cell, protein translation Vesicle - Ans →made of lipids, transport of material within the cell Plasma Membrane - Ans →phospholipid bilayer, cholesterol, semipermeable Can pass through (plasma membrane) - Ans →Hydrophobic, small uncharged polar, no charge Can't pass through (plasma membrane) - Ans →Large uncharged polar, Ions, charged, Diffusion - Ans →High concentration to Low concentration Passive transport - Ans →No energy required, Down concentration gradient (high to low) Active Transport - Ans →Needs energy, Up concentration gradient (low to high) Solution - Ans →homogeneous mixture of 2 or more substances, solute is dissolved into solvent Histology - Ans →the study of Healthy tissues Tissues - Ans →collections of cells that work together toward a common function Fixation - Ans →Preserves tissues Sectioning - Ans →makes thin slices Staining - Ans →makes structures visible Epithelial Tissue - Ans →Sheets of connective cells, outermost layer of the skin (epidermis), linings of blood vessels, GI tract, hollow organs Attachment - Ans →to eachother and to a basement membrane Avascularity - Ans →No blood vessels, must obtain nutrients by diffusion Regeneration - Ans →Life span 2-6 days, regeneration by stem cells Simple - Ans →One layer Stratified - Ans →multiple layers Squamous - Ans →Flat Cuboidal - Ans →Cube Columnar - Ans →Column Epithelial Functions - Ans →Protection, Control absorption and secretion, Location for some sensation, specialized glandular secretions Endocrine Gland - Ans →Produce hormones, travel long distance in blood stream Exocrine Gland - Ans →Secretions stay local across the glands, Sweat, has a DUCT Connective Tissue - Ans →Support and interconnect the parts of the body, Made of Cells, Fibers, Ground Substance, Vascular Extracellular Matrix - Ans →Connective tissue floats around in this (goop) Macrophages (langercell) - Ans →protection Fibroblasts - Ans →Create protein fibers of matrix Adipocytes - Ans →store lipids Fluid Matrix - Ans →Blood and lymph Solid Matrix - Ans →Cartilage and bone Gel-like Matrix - Ans →Loose and dense Areolar tissue - Ans →contains many fibers, in between organs all throughout the body, connects things, membranes, loose Adipose Tissue - Ans →tightly packed with adiposecytes, long term fat/energy storage, important padding, insulate the body Mucous membrane - Ans →lining passages to outside world Serous membrane - Ans →lining interior cavities of our body Membrane - Ans →Areolar tissue and epithelial Dense Connective Tissue - Ans →High volume of collagen fibers with scattered fibroblasts Regular Dense - Ans →tendons and ligaments Irregular Dense - Ans →Located in skin, tough outside layer of organs, Ex. Capsule of kidney integumentary system - Ans →includes skin, hair, nails, glands Six functions (integumentary system) - Ans →Protection, thermoregulation, structural support, disposal of waste, sensory receptors, synthesizes vitamin D Thin Skin - Ans →4 Layers Thick Skin - Ans →5 layers, palms of hands and soles of feet, Stratum lucidum Melanocytes - Ans →produce melanin, humans have the same # of melanocytes Melanin - Ans →pigment in skin, protects cells from UV rays, Prevents Vitimin D synthesis Eumelanin - Ans →brown, black Pheomelanin - Ans →reddish, yellow light skin - Ans →less UV is absorbed, cell damage in more lickely Dark Skin - Ans →more UV is absorbed, cell damage is less likely Dermis - Ans →two layers (papillary and reticular), hair and sweat glands, Arrector Pili muscle - Ans →goose bumps sebaceous gland - Ans →produces sebum Papillary layer - Ans →areolar tissue reticular layer - Ans →dense irregular connective tissue, collagen fibers, cleavage lines comedo (pimple) - Ans →overproduction of keratin or sebum, cloys sebacous gland Eccrine Glands - Ans →open into sweat pores, found all over the body Apocrine Glands - Ans →Open into hair follicles, Found in groin and arm pits, puberty, contains more fats hypodermis - Ans →layer of adipose connective tissue Basal Cell Carcinoma - Ans →most common form of skin cancer Squamous cell carcinoma - Ans →rises in stratum spinosum Melanoma - Ans →most deadly form of skin cancer, preexisting moles stratum basale - Ans →deepest layer of epidermis, stem cells, merkel cells- touch, melanocytes stratum spinosum - Ans →a spiny layer of the epidermis that provides strength and flexibility to the skin, desmocytes, langerhan cell- fights disease stratum granulosum - Ans →Clear layer, keratin, lipids, cells die stratum lucidum - Ans →Thick skin, dead cells stratum corneum - Ans →Outermost layer, dead keratinocytes, she's skin reticular layer of dermis - Ans →dense irregular connective tissue papillary layer of dermis - Ans →Upper layer, areolar connective tissue subatomic particles - Ans →atoms are made of... Ions - Ans →atoms that have uneven number of protons and electrons cations - Ans →atoms give up electrons easily anions - Ans →atoms accept electrons easily covalent - Ans →water consists of _____ bonds between hydrogen and water polar - Ans →is water polar or nonpolar hydrogen - Ans →______ bonds occur between polar molecules that contain hydrogen carbohydrates, lipids, proteins, nucleic acids - Ans →what are the 4 carbon containing organic molecules glycogen - Ans →how are glucose molecules stored within liver and skeletal muscles (aka whats the storage carb of animals) phospholipids, triglycerides, steroids - Ans →what are the 3 main types of lipids phospholipids - Ans →which type of lipid forms the cell organelle membrane polar hydrophilic heads, hydrophobic tails, contributes to structure of membranes - Ans →what is the phospholipid structure, and what does it contribute to? triglycerides - Ans →which lipid functions in longterm energy storage and insulation? consisting of 3 fatty acid carbon chains - Ans →what does a triglyceride look like steroids, cholesterol and steroid hormones - Ans →what type of lipids are long lipid molecules formed from carbon rings? give two examples saturated, meat and dairy products, contributes to cardiovascular disease - Ans →__________ fats, also known as your bad fats can be found in what food unsaturated, plant oils fish advocados, source of omega fatty acids - Ans →__________ fats, also known as your good fats can be found in what food amino acids - Ans →what are the monomers to the polymer protein gene expression - Ans →what is the process of making proteins from our DNA phospholipids - Ans →__________ cause the bilayer to be selectively permeable because of hydrophobic and hydrophilic regions No, its charged thus cant diffuse - Ans →Can a sodium ion (Na+) diffuse across the hydrophobic core of a phospholipid bilayer? why? yes, non polar molecules arent charged this can cross - Ans →can a steroid hormone (lipid like estrogen) diffuse across the hydrophobic core of a phospholipid bilayer? (steroid hormones are non-polar Yes, but slowly- water = polar = repulsed by phospholipids.. BUT water slips through tail cracks of membrane - Ans →can a molecule of water diffuse across the hydrophobic core of a phospholipid bilayer? why? hydrophobic molecules - Ans →what type of molecule has no charge, is non polar, and example is gases small uncharged polar moleucles (water) - Ans →what type of molecules go through the membrane slowly large uncharged polar moleucles - Ans →what type of molecules cant go across the membrane and need help ions - Ans →what type of molecules are charged and can only diffuse across membrane with help PASSIVE down (high to low) - Ans →what type of transport gradient does not require energy ACTIVE up (low to high) - Ans →what type of transport gradient requires energy passive - Ans →__________ transport does not require energy (ATP), occurs via diffusion, moves down concentration gradient facilitated diffusion, simple diffusion - Ans →what are the two types of diffusion that passive transport breaks into facilitated diffusion - Ans →what type of diffusion needs help getting through the membrane via membrane proteins? also usually selective simple diffusion - Ans →what type of diffusion moves directly through the membrane, such as steroids and gases (water slowly too) carrier mediated, channel mediated - Ans →Facilitated diffusion breaks down into 2 types of mediations... which are carrier - Ans →when a solute must bind to a protein, this described _______ mediated channel - Ans →Ions and H2O are examples of what kind of mediation leak and gated - Ans →channel mediated breaks down into 2 channels which are... leak - Ans →what channels are always open gated - Ans →what channels are opening in response to a stimulus Facilitated diffusion-------simple diffusion || || carrier channel mediated mediated || || leak channels gated channels - Ans →describe the passive transport tree (set up) Active transport - Ans →what type of transport requires energy (ATP), moves up concentration gradient from low to high, and is typically carrier mediated via pumps active - Ans →Na+/K+ pump (requires ATP) would use what kind of transport molecules must bind to carrier mediated protein first. Protein then changes shape to move the same molecules across a membrane - Ans →what characteristic differs between channel mediated and carrier mediated? Pathology - Ans →study of diseased tissues molecules, Tissues - Ans →_______ make up cells which makes up _______ epithelial, connective, muscle, neural - Ans →what are the 4 types of tissues Epithelial - Ans →what type of tissue covers exposed surfaces, lines internal passageways and chambers, and produces glandular secretions? connective - Ans →what type of tissue fills internal spaces, provides structural support, stores energy? epithelial - Ans →The epidermis is made of _______ tissue polarity, attachment, avascularity, regeneration - Ans →Epithelial tissues have 4 characteristics... (PAAR squamous - Ans →What types of epithelium look like a hella flat pancake (simple) and another like 100 hella flat pancakes squished together (stratified) Cuboidal - Ans →what types of epithelium look like a perfect singular square layer of cells (simple) and also a cube of perfect mini squares within (stratified)? Columnar - Ans →what types of epithelium look like an elongated and stretched singular layer of cells (simple) and multiple elongated and stretched layers of cells(Stratified)? Simple columnar - Ans →Epithelium of the small intestine is what kind of name simple cuboidal - Ans →Epithelium of kidney tubules is what kind of name simple squamous - Ans →Alveoli of lung is what kind of epithelium epithelial tissue - Ans →What tissue makes up the glands in our body (glands secrete substances) glands - Ans →clusters of cells that release hormones exocrine - Ans →which gland has a duct? (endocrine or exocrine) endocrine - Ans →The secretion of _____ glands tend to target tissues close to themselves Connective - Ans →what kind of tissues support and interconnect the parts of the body? cells, fibers, ground substance (extracellular matrix) - Ans →what are the three basic components of connective tissues Connective - Ans →Macrophages, fibroblasts and adipocytes are found in what types of tissue? connetive - Ans →is the following connective or epithelial tissues... lower cellularity, high extracellular matrix, not expose to outside, vascular (mostly, blood supply) epithelial - Ans →Is the following connective or epithelial tissues... highly cellular, low extracellular matrix, exposed to environment, typically avascular (no blood vessels) matrix - Ans →we can classify connective tissue by density of.... gel like matrix - Ans →proper connective tissue is described as what... Adipose tissue - Ans →what tissue stores energy for the body Areolar has more then adipose - Ans →what tissue has more protein fibers compared to the other Areolar and Adipose tissues - Ans →which tissue contains fibroblasts loose and dense - Ans →connective tissue is separated into 2 sub catagories which are... dense has more collagen fibers - Ans →what is the difference between loose and dense connective tissues Areolar and Adipose - Ans →what are the two kinds of loose connective tissues Areolar - Ans →which connective loose tissue is this (areolar or adipose) mostly matrix, low cell density, surrounds muscle fibers, blood vessels, organs, connects structures, helps form membranes adipose - Ans →which connective loose tissue is this (areolar or adipose) little matrix, deep in skin (hypodermis), surrounds organs regular, irregular, elastic - Ans →what are two kinds of dense connective tissues regular - Ans →which connective dense tissue is this (regular or irregular) fibers parallel, ligaments and tendons irregular - Ans →which connective dense tissue is this (regular or irregular) random direction of fibers, dermis of skin, walls of organs, capsules around organs Membranes - Ans →Areolar loose connective tissue i an important part of the _______ of our body mucous - Ans →(mucous or serous) membranes line passages to outside world... includes epithelial layer and areolar serous - Ans →(mucous or serous) membranes line interior body cavities and cover organs... includes epithelial layer and areolar Dense - Ans →_____ connective tissue has a high volume of collagen fibers with scattered fibroblasts regular - Ans →Regular or irregular) dense connective tissue is aligned in same direction as collagen fibers, located in tendons and ligaments Irregular - Ans →Regular or irregular) dense connective tissue run in all different directions, located in skin, GI tract and covering some organs epithelial - Ans →The salivary gland is made up of (epithelial or connective tissue) epithelial - Ans →tough outermost layer of skin is made up of (epithelial or connective tissue) connective (adipose) - Ans →under the skin is made up of (epithelial or connective tissue) Epithelial - Ans →Inner lining of the esophagus is made up of (epithelial or connective tissue)
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