Journal of Medicine, Surgery, and Public Health 5 (2025) 100173 Contents lists available at ScienceDirect Journal of Medicine, Surgery, and Public Health journal homepage: www.sciencedirect.com/journal/journal-of-medicine-surgery-and-public-health Artificial intelligence for access to primary healthcare in rural settings A R T I C L E I N F O A B S T R A C T Keywords: Healthcare Rural medicine Artificial intelligence Technology Health Artificial Intelligence (AI) may enhance access to primary health care in rural settings, especially in areas with an underserved and rural populace, due to systemic challenges in infrastructure inadequacies, shortages of trained professionals, and poor preventive measures. This paper discusses the transformative roles of AI technologies in the efforts toward bridging these gaps by improving healthcare delivery and access. With the rise of machine learning (ML) and natural language processing (NLP), AI applications may enhance diagnostic accuracy, speed up and facilitate patient interfaces, and perform resource management more optimally. This list of benefits seems promising, but the realization of AI in healthcare faces quite a few challenges: it requires ethical considerations, assurance of data safety, and sound legal frameworks. While AI, Internet of Things (IoT), and mobile health (mHealth) technologies create innovative solutions in remote monitoring and consultation, these technologies help promote prevention. Realizing the full potential of AI in rural health is thus a challenge in both infra­ structural and socio-economic spheres, requiring active collaboration. This present study indicates that it is high time there was an urgent need for high-quality research with real-world evaluation regarding the effectiveness of AI in bringing improvement in health outcomes among people in rural settings. Dear Editor, Artificial Intelligence (AI) has the potential to revolutionize access to primary healthcare [1]. Geographical isolation, inadequate health in­ frastructures, and a shortage of qualified health professionals have combined to result in poor health outcomes in rural settings [2]. Rural residents experience higher age-adjusted mortality and prevalence rates related to cardiovascular disease, diabetes, cancer, unintentional injury, and stroke [3–6]. Rural residents also have shorter life spans [7]. Besides the lack of emphasis on preventive healthcare in rural communities, combined with stigma and privacy concerns, further deters individuals from seeking necessary care [8]. Therefore, AI bridges these gaps in innovative ways to bring better healthcare delivery and make essential services more accessible to the outlying communities. AI technologies will dramatically improve the efficiency and quality of healthcare services in rural and under-reserved areas [9]. Training health workers to use AI systems will mitigate the shortage of qualified healthcare providers [10]. The access and quality of rural health services will be also improved [11]. AI tools are used for the early detection, diagnosis, and management of diseases. The neural networks, which include the convolutional and abductive networks, have demonstrated high accuracies in application areas of use [12]. Studies have indicated an urgent need for high-quality, real-world research in developing its value in healthcare and public health [13–15]. Rural population: global overview Globally, more than 3.4 billion people live in rural areas, comprising roughly 43 % of the world’s population lives in rural settings [16–19]. Most of the rural population inhabits Asia and Africa; India and China possess the largest rural populations [20]. Rural healthcare access re­ mains a significant concern due to barriers such as geographic dispersion, economic constraints, and infrastructural limitations. These populations are usually characterized by lower incomes, inadequate healthcare access, and relatively high unemployment rates compared to urban communities [21,22]. Consequently, this population is most sus­ ceptible to health disparities, which generally include higher chronic disease burdens and less access to healthcare professionals. AI technol­ ogies can bridge this gap by bringing much-needed efficiency and effectiveness in healthcare delivery to these underserved areas. It not only improves the quality of care but also saves health professional’s time in carrying out diagnoses, enabling them to be more patient-interactive and have sufficient time for treatment planning [23]. Challenges in healthcare access in rural areas Rural areas usually have significant barriers to accessing healthcare services compared to urban areas. One of the main challenges includes a shortage or lack of health infrastructures like hospitals and diagnostic facilities [24]. One more major reason behind insufficient healthcare in rural settings is a noted shortage of health professionals. Many rural populations have been shown to face shortages of primary and specialist healthcare providers, leading to poorer health and increased mortality rates compared to urban communities [25–28]. Economic hardships further hinder access, as underfunded healthcare infrastructure makes services both unavailable and unaffordable [29–31]. In addition, rural residents usually have lower levels of health knowledge and awareness [32]. Also, health education and promotion programs are often lacking in rural settings [33]. Travel distance is another major barrier, often resulting in delays that worsen health conditions, while unreliable transportation exacer­ bates the issue; for example, studies highlight transport as a key obstacle to accessing maternal and child health services [34,35]. Inadequate https://doi.org/10.1016/j.glmedi.2024.100173 Received 10 November 2024; Received in revised form 13 December 2024; Accepted 13 December 2024 Available online 15 December 2024 2949-916X/© 2024 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). M.F.H. Lamem et al. Journal of Medicine, Surgery, and Public Health 5 (2025) 100173 transport infrastructure also forces difficult prioritization of health needs in rural settings [36]. This situation is reiterated across different contexts where rural populations have to grapple with inadequate transport infrastructure, making priorities hard to make in terms of health needs [37]. Addressing these challenges demands a comprehen­ sive effort to improve healthcare funding, infrastructure, and workforce availability [38]. advice [58]. This will result in real-time advice on diagnosis, treatment options, or patient management and, when appropriate, suggestions for changes in care that will help improve outcomes [59]. Deep learning algorithms have shown considerable promise in the area of medical image processing for analyzing a variety of imaging modalities, including MRI, CT scans, and X-rays [60]. With these technologies, healthcare workers can be supported by preliminary assessment sup­ port, therefore relieving the workload and focusing their attention on patients [61]. Integration with AI and telemedicine methods has the potential to serve even the most remote sites, thereby minimizing the transportation of subjects over long distances in search of services [62]. This AI will also widen the accessibility to patient data interpretation when applied to electronic medical records (EMR) using natural lan­ guage processing (NLP) thus informed decisions could be derived [63]. This approach has emphasized the utilization of diverse data sources toward enhancing predictive accuracy, a theme similarly developed in other studies focused on diabetes [64,65]. However, the implementation of AI in healthcare is not without challenges. Ethical considerations, data security, and a need for legal frameworks remain paramount concerns that ensure AI technologies are availed responsibly and effectively [66,67]. Another aspect of engage­ ment is trust from health providers in AI, which can easily be dented with talks of accountability and perceived risk of replacement by tech­ nology [68]. Various recommendations regarding the use of AI for rural health can be made to the policymakers and healthcare practitioners for better results: Transforming medical service delivery with AI AI can potentially help extend access to health care in rural areas, at least by mitigating gaps in health resources and the workforce [39,40]. The most important advantages of AI in rural healthcare are related to improving access to disease screening and early detection. Several studies have identified that AI-based screening for diseases like diabetic retinopathy and skin cancer is cost-effective and can increase its reach in remote areas [41,42]. AI in use within a healthcare context is altering the mode of medical service delivery [43], and AI systems in healthcare are primarily designed to optimize processes, reduce dosage errors, manage medication, and make preliminary diagnoses [44]. As AI has promised to revolutionize health due to its efficiency, cost-effectiveness, and preciseness, there is a developing concern that this new trend could potentially compromise the empathetic, personalized care that conventionally characterizes the relationship between patient and pro­ vider [45]. Alarmingly, almost 50 % of the world receives consultations from physicians that are 5 minutes or less, which will begin to raise questions about the quality of care and whether such consultations can address the patient’s health concerns [46]. In this context, leveraging AI chatbots can streamline patient interactions. Recent advances in large language models (LLMs), such as ChatGPT, have shown some success in improving the quality of responses by virtual assistants in health-related scenarios [47]. As a result of this fact, allows the chatbot then to be increasingly adept at responding to more complicated health-related inquiries that might emanate from patients themselves, therefore developing an improvement in outcomes and satisfaction [48]. It can also provide timely health information, symptom understanding for patients, suggesting possible medications, reminders to take medicines, and management of chronic diseases, all of which will go a long way in improving patient compliance with treatment [49,50]. Besides, AI-driven applications in rural healthcare may also promote efficiency in service delivery for the providers. Active AI technologies can assist in automating routine tasks such as appointment settings and follow-up with patients, freeing the professionals to attend to the more complicated needs of patients [51]. This is not all; AI can also provide insight into better resource planning and patient management beyond improvement in prescription accuracy. Machine learning (ML) algo­ rithms of AI technologies can present the best practices in prescribing drugs to health professionals by analyzing huge data sets and mini­ mizing the risks of committing prescription errors [52,53]. ML and natural language processing (NLP) have been applied for diagnosis, detection, and surveillance as AI-powered technologies, and they show a high degree of accuracy on clinical tasks [54]. Mobile health (mHealth) and Internet of Things (IoT) technologies have made remote health monitoring a reality by keeping patients in homes rather than expensive healthcare facilities like hospitals or nursing homes using noninvasive and unobtrusive wearable sensors that provide continuous real-time monitoring of physiological signs and activities of the patients that can be accessed from distant facilities by the health personnel [55]. mHealth technologies, such as text messaging, have the potential to address challenges faced in rural settings in managing chronic diseases like tuberculosis, HIV, hypertension, cardiovascular disease, colorectal cancer, and pneumonia [56]. These technologies could improve health outcomes and quality of life through cost-effective healthcare solutions [57]. AI-powered clinical decision support systems (CDSS) can further help rural healthcare practitioners, who often lack access to specialist’s i. Extensive training of health practitioners to incorporate and use AI in clinical practice to achieve the relevant technology accep­ tance, trust, and competence in its application [69]. ii. Convene healthcare providers, companies developing technolo­ gies, to collaborate towards the elaboration of relevant solutions for needs at country-community levels [70]. iii. Pilot-testing of AI applications for Rural Health demonstration of proof of concept-effectiveness and best practices. iv. Engage in developing and implementing AI solutions with local communities to ensure that they respond to the particular needs of rural populations. v. Support different research in applying AI to rural health to study innovative solutions for specific health challenges. vi. Improve awareness and education among healthcare providers and patients about the benefits and limitations of AI in healthcare so that trust is inspired and adoption is increased. Conclusion In conclusion, AI application in primary healthcare holds immense prospects of improving access to and quality of healthcare in rural Bangladesh. Through AI technologies, academic health systems can surmount some of the existing barriers toward timely, effective, and equitable healthcare services. However, for the full potential of AI in transforming rural healthcare, infrastructural and socio-economic challenges need to be overcome through concerted efforts. Ethical clearance This article does not involve primary data collection or human sub­ jects, so ethical clearance is not applicable. CRediT authorship contribution statement Md Faiazul Haque Lamem: Conceptualization, Writing – original draft, Writing – review & editing. Muaj Ibne Sahid: Investigation, Visualization, Writing – review & editing. Anika Ahmed: Literature review, Resources, Review & editing. 2 M.F.H. Lamem et al. Journal of Medicine, Surgery, and Public Health 5 (2025) 100173 Funding [22] D.S.L. 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