Design and optimization of exoskeleton structure of lower limb knee joint based on cross four-bar linkage Cite as: AIP Advances 11, 065124 (2021); https://doi.org/10.1063/5.0053899 Submitted: 12 April 2021 . Accepted: 26 May 2021 . Published Online: 11 June 2021 Moyao Gao, Zhanli Wang, Shuang Li, Jing Li, Zaixiang Pang, Shuai Liu, and Zhifeng Duan COLLECTIONS This paper was selected as an Editor’s Pick ARTICLES YOU MAY BE INTERESTED IN Simulation of air pollution dispersion in Dhaka city street canyon AIP Advances 11, 065022 (2021); https://doi.org/10.1063/5.0033948 AIP Advances 11, 065124 (2021); https://doi.org/10.1063/5.0053899 © 2021 Author(s). 11, 065124 AIP Advances ARTICLE scitation.org/journal/adv Design and optimization of exoskeleton structure of lower limb knee joint based on cross four-bar linkage Cite as: AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 Submitted: 12 April 2021 • Accepted: 26 May 2021 • Published Online: 11 June 2021 Moyao Gao,a) Zhanli Wang,b) Shuang Li,c) Jing Li,d) Zaixiang Pang,e) Shuai Liu,f) and Zhifeng Duang) AFFILIATIONS School of Mechatronic Engineering, Changchun University of Technology, Changchun 130012, China a) gaomoyao@163.com Author to whom correspondence should be addressed: wangzl@ccut.edu.cn c) shuang_0313@163.com d) Lj5286@126.com e) pangzaixiang@ccut.edu.cn f) m15526835521@163.com g) 18243159982@163.com b) ABSTRACT This research introduces the knee exoskeleton system that assists in knee joint rehabilitation, which is centered on human wearing comfort. According to the bionic principle, this paper proposes a bionic knee exoskeleton structure based on a cross four-bar linkage mechanism. The cross four-bar linkage mechanism is used to simulate the internal cruciate ligament of the human knee joint to realize the instantaneous rotation center movement of the knee joint. The motor drives the telescopic rod to simulate the movement of the exoskeleton of the knee joint by the thigh muscle of the human body. The auxiliary limit locking structure simulates the knee joint patella to prevent hyperextension of the exoskeleton of the knee joint. The particle swarm-based algorithm is used to optimize the size and position of the connecting rod of the cross four-bar linkage to follow the motion of the human knee joint better. The results show that the optimized and synthesized cross four-bar linkage mechanism has a small average error value, which can better reproduce the anthropomorphic motion characteristics of the human knee joint, achieve an ideal match between the motion form of the human knee joint and the exoskeleton, and improve coordination and adaptability with human joint movement. Through the wearer test, it is found that the structure has a variable instantaneous center of rotation trajectory. Under the condition of satisfying the flexion angle and torque of the human body, the knee joint movement could be simulated with the optimal trajectory to achieve the consistency with the human knee joint movement, so as to alleviate the discomfort of the wear movement of the patients in the auxiliary rehabilitation process, and it provides an advantage for the wear comfort of the human rehabilitation movement. © 2021 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). https://doi.org/10.1063/5.0053899 I. INTRODUCTION Walking is an important part of human daily life. The phenomenon of walking inconvenience, lower limb muscle weakness, lower limb dyskinesia, and limb function decline is caused by senile diseases due to certain neuromuscular diseases, sports injuries, aging, etc. The number of these groups is increasing year by year.1 In order to improve their quality of life and make them better integrate into society, they need not only their psychological confidence but AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 also physical support. Appropriate physical support can promote the daily lives of people with functional disorders, such as neuromuscular diseases and lower limb movement disorders. Nowadays, with the rapid development of technology, exoskeleton robots have become wearable rehabilitation aid devices, which are used to assist the human body or enhance the muscle strength of the wearer. In particular, the lower extremity exoskeleton rehabilitation robot could help patients have continuous, effective, and multi-modal rehabilitation treatment, strengthen patients’ awareness of active training, 11, 065124-1 AIP Advances accelerate the recovery process of the motor function of the affected limb, achieve normal walking, and improve walking ability. The market share of lower limb exoskeleton robots in the rehabilitation industry is rapidly expanding. Compared with previous rehabilitation assistance methods, such as wheelchairs that cannot move on uneven surfaces such as stairs, lower limb exoskeleton robots enable patients to move on any surface. The main goal of the lower limb rehabilitation robot is to help patients regain better gait, reduce the workload of the therapist, provide patients with more comfortable and complete services, and improve the quality of life.2 In recent years, the lower limb exoskeleton rehabilitation robot has been heralded as a promising medical aid device for the medical rehabilitation of healthy individuals and disabled patients.3 The rapid development of robotic bionic technology has also provided new ideas for lower limb exoskeleton rehabilitation robots. Many well-known studies on walking rehabilitation-assisted exoskeleton robots have been reported. For example, the HAL series of lower limb exoskeletons from the University of Tsukuba in Japan can help patients adjust appropriate walking gait;4 eLEGS is a lower limb assisted exoskeleton robot developed by the Berkeley Bionic Laboratory of the University of California;5 and ReWalk assisted lower limb exoskeleton was developed by Israel through crutches.6 These lower extremity exoskeleton robots all have motors or hydraulic actuators on the hip/knee joints to assist in power, and they have gyroscopes and electrical sensors, such as force position or EMG, which can quickly determine the patient’s movement intention and realize the human–machine interaction. In this article, we focus on the knee exoskeleton. Numerous scientific research institutions and medical institutions at home and abroad have successively carried out research on the structure of the knee joint exoskeleton. Previous studies on the knee joint exoskeleton include the SEA elastic-driven knee exoskeleton from the Delft University of Technology7 and MIT adaptive knee exoskeleton.8,9 . In terms of knee exoskeleton robots, currently, many existing knee exoskeletons are constructed from single-axis knee joints. For knee orthoses, they have a simple hinge structure, which can be easily constructed and has good durability. However, they can only control the flexion phase but cannot fully control the walking gait phase. The actual human knee joint has an instantaneous center of rotation [Instantaneous Center of Rotation (ICR)] motion mode. In addition, the knee joint, as one of the three major joints of the lower limbs of the human body, not only needs to stabilize and protect the body but also has a certain degree to which compliance helps the lower limbs achieve normal movement.10 Due to this feature, a single-joint exoskeleton cannot fully track the motion of the human knee joint. Due to the misalignment of the center, part of the energy is lost. For multi-center joints, its structure is complex and its durability is lower than that of single-axis joints. However, the instantaneous center of rotation (ICR) changes during the rotation, which generates torque that helps to reduce the energy required by the wearer during walking.11,12 At the same time, in the walking gait phase, the change of ICR will change the distance between the foot and the ground, thereby providing the patient with a more stable movement posture.13 In recent years, due to the continuous optimization of the mechanical design of the lower extremity exoskeleton robot and the more perfect human–computer interaction system, the structure of the lower extremity exoskeleton robot has become more complex AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 ARTICLE scitation.org/journal/adv and contains more parts. However, due to the space and weight limitations of the exoskeleton robot, the anthropomorphic mechanical design must be adopted to meet the degree of freedom and movement required by the human body. The design of the lower extremity exoskeleton is similar to the design of the uniaxial knee joint.14,15 However, the human knee joint exhibits multi-axis rotation behavior,16 and these uniaxial knee joint structures cannot reproduce this behavior. In addition, because the transfer of force to the lower extremity in the non-moving direction will cause power loss, the inaccuracy of movement between the exoskeleton and the human leg may be a more critical problem for fast and dynamic gait, which will affect the normal wearer. Gait imposes kinematic restrictions or increases the mass of mechanical devices to the wearer’s body.17 The limitation of kinematics and the extra mass will bring unexpected external force to the human body, change the normal gait, and increase the metabolic cost; the efficiency of the equipment is low, and it is difficult to cooperate with the human joints to complete the coordinated rehabilitation training. However, better motion alignment, higher ground clearance, and appearance are the advantages of multi-axis knee exoskeleton robots. Many research institutions in South Korea have studied multi-axis knee exoskeleton robots. Instantaneous rotation center movement is realized by the linkage mechanism, and the fixed and mobile knee exoskeleton rehabilitation robots are applied.18–20 In recent years, other national research institutions have also applied mechanical design of various multi-axis mechanisms to modular lower limb knee exoskeleton robots.21–23 The literature uses an adaptive knee exoskeleton, which can effectively eliminate the negative impact on the human knee joint.24 In order to better adapt to the structure of the human knee joint, Technische Universität Darmstadt improved the linkage mechanism to the form of flexible joints.25 In addition to the use of linkage mechanisms for adaptive knee exoskeleton structures, there are also mechanisms such as pneumatic mechanisms, crank mechanisms, and hydraulic mechanisms that have been optimized and improved to be used in adaptive knee exoskeleton robots.26–28 We found that the multi-axis knee joint mechanism is usually used in orthotics for amputees and patients with knee injuries. It is well known that the multi-center knee joint mechanism can expand the area of voluntary knee joint stability so that the patient has a more natural gait in the knee flexion gait.29 However, as far as we know, it is still rare to find an actively driven lower extremity exoskeleton that uses a multi-center knee joint mechanism. In order to solve this problem, according to the theory of bionics, this paper designs a bionic knee exoskeleton structure based on a cross four-bar linkage mechanism that is used to simulate the cruciate ligament of the human knee joint. An auxiliary limit locking structure of the knee joint patella is simulated, and the lower limb thigh muscle is simulated with a tie rod. The instantaneous center of rotation (ICR) movement of the knee joint is realized by a motor drive, so as to reduce the discomfort of the rehabilitation patient during the exercise process and help the patient achieve a more accurate walking gait. At the same time, a method for designing and optimizing the knee joint exoskeleton structure of a lower limb rehabilitation robot is proposed to better reproduce and optimize the microstructure movement of the knee joint. This method can easily design and verify the knee joint by simply changing specific variables. The rationality of the exoskeleton 11, 065124-2 AIP Advances ARTICLE scitation.org/journal/adv structure helps patients achieve comfortable rehabilitation training. Experimental results show that the optimized and synthesized cross four-bar linkage mechanism can better reproduce the anthropomorphic characteristics of the knee joint and improve the coordination and adaptability with the motion of the human knee joint. The study of the exoskeleton structure of the bionic knee joint has a good role in promoting the lower limb exoskeleton rehabilitation robot to help patients achieve more comfortable rehabilitation training. II. BIOMECHANICS MODEL OF THE KNEE JOINT Based on the principles of ergonomics and the biomechanical structure of the human body, the analysis shows that the motion of the human knee joint is essentially multiaxial. The human knee joint includes the femur, tibia, anterior cruciate ligament, posterior cruciate ligament (Fig. 1), and knee joint. When bent, the femur will have a tendency to slide and roll on the tibia, with a variable instantaneous center of rotation (ICR) (Fig. 2). Therefore, before designing a bionic exoskeleton knee joint structure, it is very important to understand and quantify the motion form of the human knee joint. Since the human knee joint is not a single-axis joint, although many research institutions, domestic and foreign,30–32 have tried to find the instantaneous rotation center of the knee joint in the mathematical model of the human knee joint motion, still the motion trajectory of the instantaneous center of rotation of the knee joint cannot be accurately described, and there are many errors; therefore, it is necessary to quantify the instantaneous rotation center of the human knee joint and convert it into a mathematical model so that the designed bionic exoskeleton knee joint is more suitable for the human knee joint movement. In the study of the instantaneous center of rotation of the knee joint, it is found that the femoral posterior ankle bone of the human knee joint can be simulated as a spherical surface, and the three-dimensional movement of the femur on the tibia is defined.33 The expression of the average motion of knee joint flexion and extension was determined, and the center of the sphere was taken as the reference point. Figure 3 shows the radius and position of the condyle ball and the direction of the axis considered in the model. FIG. 1. Anatomical diagram of the knee joint. AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 FIG. 2. Knee joint flexion process. In order to analyze the influence of varus and internal rotation on the movement of the tibia and femoral joints in the sagittal plane, the planar knee centrode is obtained by projecting threedimensional femoral axis motion on the sagittal plane. The bestfit equations (1)–(4) for the motion parameters of varus rotation (Varus), varus (IntRot), anterior-posterior translation (Zdist), and near-distal translation (Ydist) were calculated using the knee flexion angle (F) as an independent variable as follows: Varus = (0.0791 × F) − (5.733 × 10−4 × F 2 ) − (7.682 × 10−6 × F 3 ) + (5.759 × 10−8 × F 4 ), (1) Introt = (0.3695 × F) − (2.958 × 10−3 × F 2 ) + (7.666 × 10−6 × F 3 ), (2) Ydist = (−0.0683 × F) + (8.804 × 10−4 × F 2 ) − (3.3750 × 10−6 × F 3 ), (3) Zdist = (−0.1283 × F) + (4.796 × 10−4 × F 2 ). (4) FIG. 3. Human knee joint anatomy model and ICR model generation. 11, 065124-3 AIP Advances ARTICLE Here, the knee flexion angle is measured in degrees and the displacement is measured in millimeters. These equations are used to determine the coordinates of an instantaneous knee center of rotation in the sagittal plane at a lateral distance equal to the value of the X 1 coordinate. This article assumes that the exoskeleton knee joint structure is placed at 60 mm from the origin of the inner and outer coordinate system of the knee joint (consider the distance between the skin and the exoskeleton), and at any given angle F, by using the Euler angle transformation matrix [Eq. (5)],34 the new Y and Z coordinates of the center point on the femoral axis are obtained. At the knee flexion angle of 0○ –120○ , the transformation coordinate Y 2 –Z2 of the midpoint of the Y 1 –Z1 system on the femoral axis is obtained by using the above equation. The ICR coordinates of the knee joint flexion angle are calculated. Using formula (6), the motion curve at any distance can be ⎡X2⎤ ⎡CV ⋅ CR (SF ⋅ SR + CR ⋅ SV ⋅ CF) (−CF ⋅ SR + SF ⋅ SV ⋅ CR)⎤ ⎥ ⎢ ⎥ ⎢ ⎥ ⎢ ⎥ ⎢ ⎢Y2⎥ = ⎢ −SV ⎥ CF ⋅ CV SF ⋅ CV ⎥ ⎢ ⎥ ⎢ ⎢Z2⎥ ⎢CV ⋅ SR (−SF ⋅ CR + CF ⋅ SV ⋅ SR) (CF ⋅ SR + SF ⋅ SV ⋅ SR) ⎥ ⎦ ⎣ ⎦ ⎣ ⎡X1 ⎤ ⎢ ⎥ ⎢ ⎥ (5) ⋅ ⎢Y1 ⎥, ⎢ ⎥ ⎢Z1 ⎥ ⎣ ⎦ obtained by calculating the cross section between the ICR and the vertical plane in the entire buckling range of the grid, X2 = 60, Y2 = −SV ⋅ X2 + YDIS, Z2 = CV ⋅ SR ⋅ X2 + ZDIS. (6) The coordinate of instantaneous center of rotation of the knee joint is given by the above formula. The instantaneous center of rotation is an effective tool to compare and analyze the relative motion of rigid bodies, especially the motion of the human knee joint. If a mathematical model of knee motion based on the instantaneous center of rotation (ICR) is obtained, the knee exoskeleton can more realistically simulate physiological motion through this mathematical model. scitation.org/journal/adv FIG. 4. Single-axis knee exoskeleton structure diagram. Based on the biomechanical analysis of the human knee joint, the knee exoskeleton structure similar to the human knee joint musculoskeletal system is designed according to the principle of bionics. Figure 6 shows a simple exoskeleton system that simulates the motion of the human knee joint. The two ends of the mechanism are fixed on the femur and tibia, respectively. As a simple rotational joint, the general lower extremity knee exoskeleton robot structure rotates on the sagittal plane. However, the rotation center of the human body and the knee joint used for the lower extremity exoskeleton robot is inconsistent with the bending of the human knee joint, and during the movement, the joint axis dislocation will occur. Therefore, in order to make the movement of the human knee joint and the exoskeleton knee joint consistent, the knee joint exoskeleton structure similar to the human knee joint is designed, and the four-bar linkage mechanism is used to realize the characteristics of the multi-axis knee joint. At present, the four-bar linkage mechanism is also used in a variety of rehabilitation aids. Like the lower extremity robot, this linkage mechanism has produced numerous research results.35,36 However, the cross four-bar linkage used in the rehabilitation aid equipment has better multi-degreeof-freedom controllability and structural bionics than the four-bar III. ANALYSIS OF THE BIONIC KNEE JOINT MOTION MECHANISM At present, in order to simplify the design of the knee joint, most research institutions design their knee joint exoskeleton structure as a single-axis center rotation with a single degree of freedom (as shown in Fig. 4). From the description in Sec. II, we can see that the human knee joint can be regarded as a simple hinge joint, but its function is similar to a multi-axis joint—an instantaneous center of rotation joint (shown in Fig. 5). When a single-axis knee joint exoskeleton structure is supported on a multi-axis knee joint, relative sliding will occur between the exoskeleton and the limbs. This movement can easily cause slippage and exert an unnecessary external force on the limbs. Patients wearing the exoskeleton will feel discomfort due to sliding movement and pain due to the restraining force exerted by the bandage on sliding. AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 FIG. 5. Knee movement trajectory. 11, 065124-4 AIP Advances ARTICLE scitation.org/journal/adv FIG. 6. Summary view of the knee exoskeleton structure. linkage mechanism. In addition, the cross four-bar linkage mechanism can provide multi-axis motion similar to the human knee joint, which can reduce the relative motion between the wearer and the auxiliary equipment. If relative movement is not reduced, the generated friction will scratch the user’s skin and become a major source of the additional external force of relaxation. Because the movement of the cross four-bar linkage is similar to that of a human knee joint, the cross four-bar linkage can minimize these problems and improve the comfort when wearing an exoskeleton. In view of the above-mentioned problems, this paper proposes a bionic knee exoskeleton structure based on a cross four-bar linkage mechanism. The cross four-bar linkage mechanism is used to simulate the internal cruciate ligament of the human knee joint to realize the instantaneous rotation center movement of the knee joint. The motor was used to drive the telescopic rod to simulate the movement of the human thigh muscle to drive the exoskeleton of the knee joint, and the auxiliary limit locking structure simulates the knee joint patella to prevent hyperextension of the exoskeleton of the knee joint. Figure 7(a) shows a schematic diagram of the knee joint exoskeleton robot structure. The structure has the advantages of simple structure, strong robustness, and easy processing. It could be accurately defined by mathematical models, and the overall size was changed by changing the length of the femur stem to meet the needs of people with different body lengths [Fig. 7(b)]. In this study, the cross four-bar linkage mechanism is applied to the knee joint brake module, and the length of the linkage mechanism is determined by the parameter optimization scheme described in Sec. IV (Fig. 8). In addition, the knee joint exoskeleton robot is analyzed to estimate the torque and the bending angle, which change according to the rotation of the cross four-bar linkage. The drive part of the executive module is composed of an integrated servo motor reducer. The motor selected is MYACTUATOR RMD-X10 48 V. Although the diameter of the motor is large, the integrated design of the motor reducer makes the overall weight and design of the exoskeleton lighter, and the instantaneous torque and rated power are 50 N m and 700 W, respectively. When walking on the level ground, the average maximum knee extension torque is 40.5 N m, and the maximum output power of the knee joint is 154.4 W.37 In the normal walking process, since the flexion and extension states of the knee joint are completely within the maximum range, the parameters of the four-bar linkage drive module we selected meet the conditions required by the torque and speed. The cross four-bar linkage mechanism can perform knee exoskeleton rehabilitation assisted walking exercise. Their relationship will be introduced in Sec. IV. AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 FIG. 7. Knee joint exoskeleton structure. IV. LOCATING THE ICR OF A FOUR-BAR LINKAGE In order to drive the knee joint exoskeleton cross four-bar linkage, the drive motor is connected to the tibial base frame (L1) (Fig. 9) through a telescopic rod. By using the cosine law based on the given special angle fixed point, we derive the mapping function of the angle from the knee actuator θac to the knee joint θKnee from the cosine law as follows: θKnee = f (θac ). (7) 11, 065124-5 AIP Advances ARTICLE scitation.org/journal/adv FIG. 9. Analytical model of the knee joint exoskeleton linkage mechanism. four links cross is the instantaneous center of rotation of the knee joint. Figure 11 shows the position of the reference four-bar linkage. Using the Freudenstein equation link mechanism analysis method, a closed-loop structure is created around the link for the position analysis of the four-bar mechanism. The size of the position vector is the link length of the four-bar mechanism to be synthesized.39 α is the input angle because the exoskeleton linkage mechanism will be braked by the thigh during walking. Similarly, the inclination of link 1 (β) can be known from the initial configuration. The relationship between the angle θ3 and other four-bar linkage parameters to define the complete configuration of the four-bar linkage at any moment is found as follows: AB + BC = AD + DC, (8) FIG. 8. Cross four-bar linkage model of the exoskeleton mechanism. When the knee joint flexes, it drives the tibial base frame (L1) and the connecting rod (L2) rotate. The ICR of the cross four-bar linkage mechanism (the same as the intersection of L2 and L3 in this figure) moves along a predetermined path, which is most similar to the ICR of the human knee joint. Since the system assists the wearer’s legs through multi-axis motion, it helps to maintain the comfort and restraint between the wearer and the system by reducing friction. Using the cross four-bar linkage mechanism, the torque and speed of the system are controlled by the operation of the motor connected to the truss frame. In the initial state, the system generates high speed and low torque. When the rotation angle increases (the wearer’s knee joint is bent), the speed decreases and the torque increases. The motor drive module in this study uses a coupler to drive the telescopic rod to move. From the literature,38 the force of the cross four-bar linkage is calculated with the change in the knee joint bending angle (Fig. 10). The displacement analysis of the cross four-bar linkage can be expressed in a mathematically closed form according to the length and position of the four rods of the actuator. The point where the AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 FIG. 10. Bending angle and force diagram of the connecting rod. 11, 065124-6 AIP Advances ARTICLE cos θ3 = scitation.org/journal/adv 1 − tan2 ( θ23 ) 1 + tan2 ( θ23 ) , θ3 θ3 ) + B tan + C = 0 2 2 a simplification is obtained as follows: √ −B ± B2 − 4AC θ3 = 2 ⋅ arctan( ). 2A A tan2 ( B(−l3 cos θ3 , l3 cos θ3 ), (9) Using the coordinates of the two points l42 = [l1 − l2 cos α + l3 cos θ3 , l2 sin α − l3 cos θ3 ] ⋅ [l1 − l2 cos α + l3 cos θ3 , I2 sin α − l3 cos θ3 ], (10) the following formula is obtained: l42 − l12 − l22 − l32 + 2l1 l2 cos α − 2l1 l3 cos θ3 + 2l2 l3 cos(α − θ3 ) = 0, (11) R1 = l1 , l2 (12) R2 = l1 , l3 (13) l2 − l2 − l2 − l2 R3 = 4 1 2 3 , 2l2 l3 (14) A = R2 ⋅ cos α + cos α + R3 − R1, (15) B = 2 sin α, (16) C = R2 ⋅ cos α − cos α + R3 − R1. (17) Using the trigonometric formulas sin θ3 = 2 tan θ23 , 1 + tan2 ( θ23 ) (19) (20) During knee flexion, the tibia rotates around the femur around the knee joint, that is, connecting rod 1 (L1) rotates with respect to connecting rod 4 (L4) centered on ICR, and ICR connects rod 2 (L2) and Link 3 (L3) passes through the intersection of two straight lines. The first line passes through pivot points A and C, and the second line passes through pivot points B and D of the four-bar linkage, as shown in Fig. 11. The equations of the two straight lines are calculated in the form of slopes [see Eq. (20)]. FIG. 11. Mathematical model of the cross four link mechanism. C(l1 − l2 cos α, l2 sin α). (18) V. KNEE JOINT OPTIMIZATION BASED ON PARTICLE SWARM OPTIMIZATION As the four-bar mechanism moves, the actual output trajectory has deviated from the expected movement trajectory. For this reason, many scholars have studied the parameter optimization of the four-bar mechanism and produced different design and optimization methods. Using genetic algorithm (GA) optimization or Gauss–Newton iterative algorithm optimization and other optimization methods to improve it, the optimization objective function is established, and the optimal simulation parameters are obtained through MATLAB software, which can effectively reduce the lateral and initial trajectory errors.40–42 However, for high-precision driving devices, the lateral and initial errors of the four-bar mechanism are difficult to meet the design requirements, and the GA coding is more complicated and less efficient. However, based on the swarm intelligence proposed by Kennedy and Eberhart in 1995, Particle Swarm Optimization (PSO) is an evolutionary computing technology. It originated from the study of bird predation and is considered an iterative-based optimization tool.43 Obviously, the pace of evolution slowed down later because random particles are often at the same level in the optimization process and tend to fall into the local optimum solutions. The particle swarm optimization algorithm is also a multidisciplinary field, which can be abstracted as a numerical function optimization problem, and it can effectively solve the phenomenon that the PSO algorithm is easy to be premature and the algorithm is easy to oscillate near the global optimal solution.44 In this regard, if the particle swarm optimization algorithm is used to optimize the parameter variables of the four-bar mechanism, the error variation curve of the optimized four-bar mechanism can be obtained, so that the error of the four-bar mechanism can be reduced, which provides a theoretical basis for further study of the motion error of the spatial four-bar mechanism, −l1 sin β ⋅ l2 cos α − l1 sin β ⋅ l4 cos θ3 + l1 cos β ⋅ l2 sin α − l1 cos β ⋅ l4 sin θ3 , tan α ⋅ l1 cos β − tan α ⋅ l4 cos θ3 − l1 sin β − l4 sin θ3 −l1 sin β ⋅ l2 cos α − l1 sin β ⋅ l4 cos θ3 + l1 cos β ⋅ l2 sin α − l1 cos β ⋅ l4 sin θ3 Y = tan α ⋅ . tan α ⋅ l1 cos β − tan α ⋅ l4 cos θ3 − l1 sin β − l4 sin θ3 X= AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 (21) 11, 065124-7 AIP Advances ARTICLE In this paper, the geometric parameters of the cross four-bar linkage mechanism are optimized by introducing particle swarm optimization. A schematic diagram of the connecting rod size and motion angle model of the plane cross four-bar mechanism is created, and the horizontal and vertical equations of the motion track points through the vector relationship are solved. The parameter variables of the four-bar mechanism are analyzed, the lateral and initial error functions of the motion trajectory are calculated, and the motion conditions of the four-bar mechanism are restricted. The particle swarm optimization algorithm is used to search for the optimal value of the geometric parameters of the four-bar mechanism. A. Objective function When the bionic exoskeleton knee joint cross-four-bar mechanism is more similar to the ICR of the human knee joint, the cross four-bar linkage mechanism and the human knee joint movement coordination will be better. Therefore, the optimization objective of this paper is to find a four-bar linkage mechanism that can simulate the instantaneous rotation center movement of the anatomical knee joint under the condition of satisfying the constraints. This can be achieved by minimizing the distance between the instant center of the composite four-bar linkage and the knee joint motion center. Therefore, the objective function is to minimize the Euclidean norm square variance of the vector from the i-th point of the reference center of the knee joint xI to the i-th point of the cross four-bar linkage instantaneous center point xF , (22) i−1 B. Constraint condition Before constraint optimization, it is necessary to limit the length of the four-bar mechanism to an appropriate scale to limit the size of the four-bar mechanism so that its entire range of motion matches the size of the human knee joint. According to the published research on the size and range of motion of the femur and tibia of the human knee joint structure,45 the connecting rod size in the literature20 is taken as the basic size before the optimization of the cross four-bar linkage. The knee joint exoskeleton cross four-bar linkage mechanism designed in this paper can be defined according to the parameters of the dual rocker mechanism. Therefore, the constraint conditions of the four-bar mechanism should be satisfied as follows: (1) the femoral connecting rod is the longest and the tibia connecting rod is the shortest; (2) the sum of the length of the shortest rod and the longest rod is less than the sum of the lengths of the other two rods. Therefore, the motion constraint conditions of the four-bar mechanism are 20 ≤ l1 , l2 , l3 , l4 ≤ 60, (23) l1 + l4 < l2 + l3 . (24) VI. RESULT A. Optimized analysis Compared with other optimization methods, the optimization process of the particle swarm algorithm makes the AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 solution of the cross four-bar linkage more convenient and accurate. Finally, the optimal solution of the cross four-bar mechanism is obtained, and at the same time, it can give the wearer a comfortable walking posture under the condition that the mechanism is fully rotated. In addition, the restrictions on the mechanism and the range of motion have been made in advance, and the optimal solution of the cross four-bar mechanism was finally determined. Figure 12(a) shows a schematic diagram of the optimized front knee joint ICR motion trajectory (blue line) and four-link motion trajectory (red line). Through the optimization analysis of the position, length, and angle of the link, combined with the determination of the parameter size of the connecting rod in the literature,35 Fig. 12(b) shows the results of the optimization of the motion curve of the cross four-bar linkage by the genetic algorithm in the range of 0○ –120○ of the human knee joint movement. Figure 12(c) shows the results of the optimization of the motion curve of the cross fourbar linkage by particle swarm optimization in the range of 120○ of the human knee joint movement. Through comparative analysis, we found that the trajectory of the cross-bar linkage mechanism following the human knee joint by particle swarm optimization is more accurate, and the average error range of the knee joint axis point and the value of the instantaneous center point of the cross four-link are less than 1 mm. The optimized parameters of the cross four-bar linkage mechanism are shown in Table I. B. Tests n F(x)min = ∑ [(xI − xF )2 − (yI − yF )2 ]. scitation.org/journal/adv To test the feasibility and applicability of the knee exoskeleton robot flexion and extension, first, we tested the flexion and extension exercises of healthy volunteers (male; height, 177 cm; weight, 65 kg) in the closed loop position of the exoskeleton robot and applied rotational flexion and extension exercises to the subjects (as shown in Fig. 13), and the volunteers were fixed on the exoskeleton of the knee joint at the same time. For testing the utility of the knee exoskeleton, the only two basic measurements are the knee bending angle and the torque between the legs on the sagittal plane. Taking into account the geometric shape of the four-bar linkage mechanism and the movement of the center of rotation, it is necessary to determine the value by measuring the geometric relationship and the angle between any two linkages (Fig. 14). Through the geometric relationship of the two linkages shown in Fig. 9 in Sec. IV, we obtain the bending angle changes of the knee joint. The torque tracking performance of the knee exoskeleton was tested at a clear flexion angle. Figure 15 shows the simulation and experimental results of torque tracking. During this period, volunteers voluntarily wore the device, and it can be observed that the torque tracking performance of the knee exoskeleton is very satisfactory for rehabilitation exercises. In the whole knee flexion range, it can be observed in the process of torque trajectory change. Due to the small range of motion at the knee joint, the deviation of some large torques appears in the simulation process. In the actual detection process, it is in line with the knee exoskeleton walking gait torque range value. Finally, in order to further prove the effectiveness of the assistance provided by the knee exoskeleton robot, the changes in the flexion angle torque of the knee exoskeleton were detected when walking and without assistance. The solid line in Fig. 16 indicates 11, 065124-8 AIP Advances ARTICLE scitation.org/journal/adv TABLE I. Connecting rod size optimization parameters. L1 44.8 mm L2 L3 L4 β 52.2 mm 47.7 mm 40.4 mm 27.8○ the changes in the flexion torque of the knee when the knee flexion is 0○ –120○ . Specifically, the wearer was in a standing state, and the wearer performed unilateral leg flexion tests and full gait cycle walking tests by wearing a knee exoskeleton. FIG. 13. Structure of the exoskeleton knee joint. FIG. 12. (a) Trajectory diagram before optimization, (b) GA optimized trajectory diagram, and (c) PSO optimized trajectory diagram. AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 FIG. 14. Connecting rod motion model diagram. 11, 065124-9 AIP Advances ARTICLE scitation.org/journal/adv FIG. 15. Simulation experiment verification. caused by joint dislocation. The design of the bionic knee exoskeleton robot in this study provides a good promotion for the comfort of wearers’ movement. At the same time, the optimization design of the exoskeleton structure will help to play an important reference role in the structural design of the lower limb exoskeleton rehabilitation robot and help patients to achieve more comfortable rehabilitation training. ACKNOWLEDGMENTS FIG. 16. Knee joint exoskeleton flexion torque test. This research was supported by the National Natural Science Foundation of China (Grant No. 5187052524). This work was supported, in part, by the National Natural Science Foundation of China under Grant No. 61873304, the China Postdoctoral Science Foundation Funded Project under Grant Nos. 2018M641784 and 2019T120240, and the Key Science and Technology Projects of Jilin Province, China, under Grant No. 20200404208YY. The authors declare no conflict of interest. DATA AVAILABILITY This study measured that the knee exoskeleton structure has good compliance and comfort in standing, walking, and flexion at different flexion angles, and it will not cause discomfort in wearing the legs due to large-angle bending. In the stage of standing and walking, the limit baffle and the locking mechanism can keep the joint in a comfortable position to prevent the secondary injury of the knee joint caused by the overload of the exoskeleton structure. Therefore, this research proposes that the exoskeleton structure of the knee joint is feasible in actual sports. VII. CONCLUSIONS In this research, a bionic knee exoskeleton robot centered on human wearing comfort is introduced. The exoskeleton structure simulates the design of the cruciform ligament of the human knee joint skeletal muscle system. By introducing its principle and functional characteristics, a knee exoskeleton structure based on the cross four-bar mechanism is proposed to optimize and realize the instantaneous rotation center motion of the knee exoskeleton. Through the wearer test, the knee exoskeleton robot can reproduce the anthropomorphic characteristics of the knee joint well and improve the coordination and adaptability with human joint motion. Under the condition of standing and walking flexion of the knee exoskeleton structure, the knee exoskeleton robot can follow well the human knee joint movement and will not produce the wear discomfort AIP Advances 11, 065124 (2021); doi: 10.1063/5.0053899 © Author(s) 2021 The data that support the findings of this study are available from the corresponding author upon reasonable request. REFERENCES 1 C. J. Chen, X. Y. Wu, D. X. Liu, W. Feng, and C. Wang, “Design and voluntary motion intention estimation of a novel wearable full-body flexible exoskeleton robot,” Mobile Inf. Syst. 2017, 1. 2 J.-H. Kim, M. Shim, D. H. Ahn, B. J. Son, S.-Y. Kim, D. Y. Kim, Y. S. Baek, and B.-K. Cho, “Design of a knee exoskeleton using foot pressure and knee torque sensors,” Int. J. Adv. Rob. Syst. 12(8), 112 (2015). 3 B. Chen, B. Zi, Z. Wang, L. Qin, and W.-H. Liao, “Knee exoskeletons for gait rehabilitation and human performance augmentation: A state-of-the-art,” Mech. Mach. 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