Chapter 31 Nursing Management: Obstructive Pulmonary Diseases Focus on Asthma Asthma—Definition Chronic inflammatory disorder of airways Causes airway hyper-responsiveness leading to wheezing, breathlessness, chest tightness, and cough 31B-2 Significance About 8.4% of Canadians over the age of 12 are living with asthma. About 11% of people with asthma visit an emergency department (ED) one or more times a year. Morbidity is dramatic. 31B-3 Triggers of Asthma: Allergens May be seasonal or year-round, depending on exposure to allergen Animal dander House dust mites Cockroaches Pollens Moulds 31B-4 Triggers of Asthma: Exercise Induced or exacerbated after exercise Pronounced with exposure to cold air • Breathing through a scarf or mask may ↓ likelihood of symptoms 31B-5 Triggers of Asthma: Respiratory Infection Major precipitating factor of an acute asthma attack ↑ Inflammation hyper-responsiveness of the tracheobronchial system Can last 2–8 weeks Influenza vaccines are recommended for children 6 months and older and for adults with asthma. 31B-6 Triggers of Asthma: Nose and Sinus Conditions Allergic rhinitis and nasal polyps Large polyps are removed. Sinus conditions are usually related to inflammation of the mucous membranes. 31B-7 Triggers of Asthma: Medications and Food Additives Asthma triad: Nasal polyps, asthma, and sensitivity to Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) Wheezing develops in about 2 hours. Sensitivity to salicylates • Found in many foods, beverages, and flavourings β-Adrenergic blockers 31B-8 Triggers of Asthma: Medications and Food Additives (Cont.) Food allergies may cause asthma symptoms. Avoidance diets 31B-9 Triggers of Asthma: Gastroesophageal Reflux Disease (GERD) Exact mechanism is unknown. Reflux of acid could be aspirated into lungs, causing bronchoconstriction. 31B-10 Triggers of Asthma: Air Pollutants Can trigger asthma attacks Wood smoke Vehicle exhaust Diesel particulate Elevated ozone levels Sulphur dioxide Nitrogen dioxide 31B-11 Triggers of Asthma: Emotional Stress Psychological factors can worsen the disease process. Attacks can trigger panic and anxiety. Extent of the effect is unknown. 31B-12 Pathophysiology Early-phase response is characterized by bronchospasm. Increased mucus secretion, edema formation, and increased amounts of tenacious sputum Peaks in 30–60 minutes after trigger exposure Subsides in about 30–90 minutes 31B-13 Pathophysiology (Cont.) Late-phase response can be more severe than the early-phase response and is primarily inflammation. Peaks in 5–12 hours May last several hours to days Corticosteroids are effective in preventing and reversing this cycle. 31B-14 Early-Phase Response of Asthma Triggered by Allergen 31B-15 Factors Causing Obstruction 31B-16 Pathophysiology (Cont.) Late-phase response If airway inflammation is not treated or does not resolve, it may lead to irreversible lung damage. 31B-17 Clinical Manifestations Unpredictable and variable Recurrent episodes of wheezing, breathlessness, cough, and tight chest Particularly at night or early morning (0200–0500 hours) May be abrupt or gradual Lasts minutes to hours 31B-18 Clinical Manifestations (Cont.) Expiration may be prolonged. Inspiration-expiration ratio of normal, 1:2, is increased to 1:3 or 1:4. Bronchospasm, edema, and mucus in bronchioles narrow the airways Air takes longer to move out. 31B-19 Clinical Manifestations (Cont.) Wheezing is unreliable to gauge severity. Severe attacks may have no audible wheezing. Usually begins upon exhalation “Silent chest” 31B-20 Clinical Manifestations (Cont.) Cough variant asthma Cough is the only symptom. Bronchospasm is not severe enough to cause airflow obstruction. 31B-21 Clinical Manifestations (Cont.) Difficulty with air movement Patient may feel increasingly anxious 31B-22 Clinical Manifestations (Cont.) An acute attack usually reveals signs of hypoxemia. Restlessness ↑ Anxiety Inappropriate behaviour 31B-23 Clinical Manifestations (Cont.) More signs of hypoxemia ↑ Pulse and blood pressure (BP) Pulsus paradoxus (drop in systolic BP during inspiratory cycle >10 mm Hg) Respiratory rate >30 breaths/minute 31B-24 Complications Status asthmaticus (form of acute asthma attack) Common causes of severe, acute attacks include viral illnesses, ingestion of Aspirin or other NSAIDs, increases in environmental pollutants or other allergen exposure, and discontinuation of medication therapy. Clinical manifestations are similar to those of nonsevere asthma but are more serious and prolonged. 31B-25 Complications (Cont.) Status asthmaticus (form of acute asthma attack) (Cont.) May include pneumothorax, pneumomediastinum, acute cor pulmonale with right ventricular failure, and severe respiratory muscle fatigue that leads to respiratory arrest Respiratory arrest can be fatal. 31B-26 Diagnostic Studies Detailed history and physical exam Pulmonary function tests Chest X-ray Arterial blood gases (ABGs) Oximetry Allergy testing Blood levels of eosinophils Sputum culture and sensitivity 31B-27 Interprofessional Care Education Start at time of diagnosis Integrate throughout care 31B-28 Interprofessional Care (Cont.) Self-management Tailored to needs of patient Culturally sensitive 31B-29 Interprofessional Care (Cont.) Overall goal Achieve asthma control with minimum level of pharmacotherapy while enhancing quality of life of individuals living with asthma and reducing the personal and social burdens inflicted by the condition 31B-30 Interprofessional Care (Cont.) General management approach Confirming the diagnosis Monitoring level of asthma control Reducing exposure to environmental triggers Providing appropriate medications Providing asthma education Providing written action plan Ensuring regular follow-up 31B-31 Interprofessional Care (Cont.) Acute asthma exacerbation Often come to ED Respiratory distress Treatment depends on severity and response to therapy. • Severity measured with flow rates 31B-32 Interprofessional Care (Cont.) Acute asthma exacerbation (Cont.) Oral corticosteroids Therapy may be started and monitored with pulse oximetry or ABGs in severe cases. 31B-33 Interprofessional Care (Cont.) Severe attack Most therapeutic measures are the same as for acute episode. • ↑ In frequency and dose of bronchodilators May require mechanical ventilation 31B-34 Interprofessional Care (Cont.) Severe attack (Cont.) IV corticosteroids are administered every 4–6 hours, then are given orally. Continuous monitoring of patient is critical. 31B-35 Interprofessional Care (Cont.) Severe attack (Cont.) Supplemental O2 is given by mask or nasal cannula for 90% O2 saturation. • An arterial catheter may be used to facilitate frequent ABG monitoring. IV fluids are given because of insensible loss of fluids. 31B-36 Medication Therapy Controllers Achieve and maintain control of persistent asthma Relievers Treat symptoms of exacerbations 31B-37 Medication Therapy (Cont.) Three types Anti-inflammatory: Corticosteroids Antileukotrienes Biological therapy (monoclonal antibody to IgE) 31B-38 Medication Therapy (Cont.) Corticosteroids (e.g., fluticasone, budesonide) Suppress inflammatory response Inhaled form is used in long-term control Systemic form to control exacerbations and manage persistent asthma 31B-39 Medication Therapy (Cont.) Corticosteroids (Cont.) Reduce bronchial hyper-responsiveness Decrease mucus production Taken on a fixed schedule 31B-40 Medication Therapy (Cont.) Corticosteroids (Cont.) Oropharyngeal candidiasis, hoarseness, and a dry cough are local adverse effects of inhaled medication. • Can be reduced using a spacer or by gargling after each use 31B-41 Spacer 31B-42 Medication Therapy (Cont.) Antileukotriene (e.g., zafirlukast, montelukast) Block action of leukotrienes—potent bronchoconstrictors 31B-43 Medication Therapy (Cont.) Antileukotriene (Cont.) Has both bronchodilator and anti-inflammatory effects Not indicated for acute attacks Used for prophylactic and maintenance therapy 31B-44 Medication Therapy (Cont.) Biological therapy: Anti-IgE (e.g., omalizumab [Xolair]) ↓ Circulating free IgE levels Prevents IgE from attaching to mast cells, preventing release of chemical mediators Subcutaneous administration every 2–4 weeks 31B-45 Medication Therapy (Cont.) Three types of bronchodilators β2-Adrenergic agonists Methylxanthines Anticholinergics 31B-46 Medication Therapy (Cont.) β-Adrenergic agonists (e.g., salbutamol, terbutaline) Effective for relieving acute bronchospasm Onset of action in minutes and duration of 4–8 hours 31B-47 Medication Therapy (Cont.) β-Adrenergic agonists (Cont.) Prevent release of inflammatory mediators from mast cells Not for long-term use 31B-48 Medication Therapy (Cont.) Methylxanthines (e.g., theophylline) Less effective long-term bronchodilator Controller after trying inhaled corticosteroid (ICS), long-acting β2 agonist (LABA), and leukotriene receptor antagonists (LTRAs) Narrow toxic/therapeutic ratio and frequent adverse events 31B-49 Medication Therapy (Cont.) Anticholinergic medications (e.g., ipratropium) Block action of acetylcholine Usually used in combination with a bronchodilator Most common adverse effect is dry mouth 31B-50 Patient Teaching Related to Medication Therapy Correct administration of medications is a major factor in success. Inhalation of medications is preferable to avoid systemic adverse effects. • Metered-dose inhalers (MDIs) (with and without spacers), dry powder inhalers (DPIs), and nebulizers are devices used to inhale medications. 31B-51 Patient Teaching Related to Medication Therapy (Cont.) Correct administration of medications Using an MDI with a spacer is easier and improves inhalation of the medication. A DPI requires less manual dexterity and coordination. 31B-52 Example of DPI 31B-53 Nursing Management: Assessment Health history Especially of precipitating factors and medications ABGs Lung function tests 31B-54 Nursing Management: Assessment (Cont.) Physical examination Use of accessory muscles Diaphoresis Cyanosis Lung sounds 31B-55 Nursing Management: Diagnoses Inadequate airway clearance Anxiety Inadequate knowledge 31B-56 Nursing Management: Planning Overall goals Participate in activities of normal life (including exercise and other physical activity) with little to no interference Normal or near-normal pulmonary function Have the asthma under control 31B-57 Nursing Management: Planning (Cont.) Overall goals (Cont.) Few or no adverse effects from medication Adequate knowledge and skills to participate in and carry out management 31B-58 Nursing Management: Implementation Asthma education Develop partnership with family Provide information and education Collaborate with family to develop skills necessary for controlling asthma Self-management education programs can reduce the number of ED visits, hospitalizations, urgent care visits, nocturnal awakening, and days of interrupted activity. 31B-59 Nursing Management: Implementation (Cont.) Asthma education (Cont.) Asthma education programs can be cost-effective. See Table 31.9 for a detailed basic education program. 31B-60 Nursing Management: Implementation Environmental control Reduce triggers (allergens and irritants) House dust mites; focus on bedroom and keeping relative humidity below 50%, laundering bed linens in hot water, and removing carpets Pet dander strategies for reduction Eliminate environmental tobacco smoke Exercise within patients’ limits Work-related asthma 31B-61 Nursing Management: Implementation (Cont.) Self-monitoring and action plans Every person with asthma should have an action plan. Include self-monitoring, by symptoms and peak expiratory flow (PEF), regular medical review Involve the patient’s family for increased adherence to the plan. 31B-62 Nursing Management: Implementation (Cont.) Inadequate airway clearance Monitor respiratory and cardiovascular systems. • Lung sounds • Respiratory rate • Pulse • BP Position patient to maximize ventilation 31B-63 Nursing Management: Implementation (Cont.) Anxiety An important goal of nursing is to ↓ the patient’s sense of panic. • Stay with the patient. • Encourage slow breathing using pursed lips for prolonged expiration. • Position the patient comfortably. 31B-64 Nursing Management: Implementation (Cont.) Inadequate knowledge Patient education Asthma plan Must learn about medications and develop self- management strategies Patient and health care provider must monitor responsiveness and adverse events to medication 31B-65 Nursing Management Nursing Implementation (Cont.) Peak flow results Green Zone • Usually 80% to 100% of personal best • Remain on medications. Peak flow results Yellow Zone Usually 50% (60%) to 79% of personal best Indicates caution Something is triggering asthma. Copyright © 2019 Elsevier Canada, a division of Reed Elsevier Canada, Ltd. 66 Nursing Management Nursing Implementation (Cont.) Peak flow results Red Zone • 56% to 60% or less of personal best • Indicates serious problem • Definitive action must be taken with health care provider. Copyright © 2019 Elsevier Canada, a division of Reed Elsevier Canada, Ltd. 67 Case Study Case Study A 30-year-old patient comes to the emergency department with severe wheezing, dyspnea, and anxiety. The patient recently had a cold that did not resolve. 31B-69 Case Study (Cont.) Has taken a new job at a dry cleaners and laundromat Has been having regurgitation of food after eating, which the patient related to the stress from her recent divorce 31B-70 Case Study (Cont.) Upset that the children had just brought home a stray cat Does not know if they are allergic to the cat 31B-71 Discussion Questions 1. 2. What possible asthma triggers may the patient be experiencing? Are there any possible triggers that the patient can avoid or manage? 31B-72 Discussion Questions (Cont.) 3. 4. What are the priorities of care? What patient teaching topics should the nurse cover with the patient? 31B-73
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