PHARMACOECONOMICS
REFLECTION 9: Climate Sensitive Diseases: Dengue Fever
Name:
Section: DOP1A
Date: March 14, 2025
Reflection 9: Climate Sensitive Diseases: Dengue
Speaker:
Time: March 14, 2025 2:00-3:00 pm
Dengue fever is a viral illness caused by the dengue virus and transmitted primarily by Aedes aegypti and
Aedes albopictus mosquitoes. These mosquitoes are found predominantly in tropical and subtropical
regions like the Philippines, where the environment provides ideal breeding grounds due to the warm
temperatures and high humidity. Infected individuals typically present with sudden high fever, severe
headaches, pain behind the eyes, muscle and joint pain, rashes, and in some cases, bleeding. Severe forms
of the disease, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), can be fatal if
not diagnosed and treated promptly, making the disease a serious public health concern in the country.
The mosquitoes responsible for dengue transmission, namely Aedes aegypti and Aedes albopictus, are
most active in urban areas where human activity provides ample opportunities for feeding and breeding.
These mosquitoes breed in stagnant water found in containers such as flowerpots, old tires, water storage
drums, and even discarded trash. Urban areas with poor waste management practices and inadequate
water storage facilities are particularly vulnerable to dengue outbreaks, as they provide numerous
breeding sites for mosquitoes to thrive. The dense population of these urban areas also increases the
likelihood of virus transmission from infected mosquitoes to humans, leading to more frequent and larger
outbreaks.
Dengue fever is highly climate-sensitive, with environmental factors such as rainfall, temperature, and
humidity directly influencing the spread of the disease. In the Philippines, the rainy season, which typically
occurs from June to November, creates abundant breeding sites for mosquitoes as stagnant water
accumulates in various containers and debris around homes and communities. These breeding sites are
ideal for mosquito larvae, which develop in still water before maturing into adult mosquitoes capable of
transmitting the dengue virus. Warmer temperatures, which are characteristic of tropical climates,
accelerate the development of mosquito larvae and shorten the virus's incubation period inside the
mosquito, leading to quicker transmission rates. Furthermore, high humidity levels, especially during the
rainy season, help mosquitoes survive and thrive, prolonging the potential for dengue transmission. The
overall climate in the Philippines, combined with ongoing changes due to global climate change, makes
the country especially vulnerable to the cyclical nature of dengue outbreaks, as the combination of these
factors creates an environment where mosquitoes and the virus can flourish.
Diagnosis of dengue fever is typically based on the patient's clinical symptoms, as many of the signs of the
disease are distinctive, such as the sudden onset of high fever, severe headache, retro-orbital pain (pain
behind the eyes), and a characteristic rash. However, since these symptoms overlap with those of other
viral infections, laboratory tests are necessary to confirm the diagnosis. Diagnostic tests commonly used
include serological tests to detect antibodies (IgM and IgG) produced by the immune system in response
to the virus, as well as polymerase chain reaction (PCR) tests to detect the genetic material of the virus in
the patient’s blood. The IgM antibodies indicate a recent infection, while the presence of IgG antibodies
PHARMACOECONOMICS
REFLECTION 9: Climate Sensitive Diseases: Dengue Fever
may indicate a past infection or prior exposure to the virus. In more severe cases of dengue, a complete
blood count (CBC) is often used to monitor the patient's platelet count, which may drop significantly, as
well as other markers of disease severity. Early diagnosis and timely medical intervention are critical, as
severe dengue can quickly progress to life-threatening conditions like dengue hemorrhagic fever (DHF) or
dengue shock syndrome (DSS), which require intensive care and close monitoring.
Currently, there is no specific antiviral treatment for dengue fever. Management of the disease focuses
primarily on supportive care aimed at relieving symptoms and preventing complications. For mild cases,
treatment typically involves rest, hydration, and the use of acetaminophen (paracetamol) to reduce fever
and alleviate pain. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen, are
avoided, as they can increase the risk of bleeding, which is a common complication in severe dengue. The
most important aspect of dengue management, especially in severe cases, is maintaining adequate fluid
balance to prevent dehydration and shock, which can be fatal. Intravenous (IV) fluids are often
administered in hospitals to maintain blood pressure and circulation. In severe cases, where dengue
hemorrhagic fever or dengue shock syndrome occurs, close monitoring of vital signs and careful
management of fluid and electrolytes is essential. In addition to intravenous fluid therapy, blood
transfusions may be necessary for patients experiencing significant bleeding or a drastic drop in platelet
count.
Prevention of dengue fever relies heavily on reducing the mosquito population and minimizing exposure
to mosquitoes. The Philippine government and public health organizations have implemented various
control measures, including the 4S strategy, which encourages individuals and communities to take
preventive actions against dengue. The 4S strategy stands for: Search and destroy mosquito breeding sites,
Seek early medical consultation for dengue symptoms, Support fogging and spraying operations to kill
adult mosquitoes, and practice Self-protection measures, such as wearing long-sleeved clothing and using
insect repellent. These measures aim to reduce the number of mosquitoes and prevent further
transmission of the virus.
In conclusion, dengue fever is a persistent and growing public health issue in the Philippines, exacerbated
by the country's tropical climate and urbanization. The Aedes mosquitoes responsible for transmitting the
virus thrive in the country's warm, humid conditions, with the rainy season providing ideal breeding sites.
Effective management of dengue requires early diagnosis, supportive care, and widespread prevention
efforts, including the 4S strategy. Community engagement is essential in reducing mosquito breeding sites
and minimizing the risk of outbreaks. While ongoing research into vaccines and more effective treatments
for dengue holds promise, addressing the environmental factors that contribute to mosquito proliferation
will remain a critical component of controlling the spread of the disease in the Philippines.