Gas Exchange and the Respiritory System How does the human body exchange gases? • Aerobic respiration requires oxygen (O2) and produces carbon dioxide (CO2). • Organisms have special surfaces to take in O2 and get rid of CO2. • Since O2 enters and CO2 exits the body, such surfaces are for gas exchange. • The lungs comprise the human gas exchange surface, the place where gas exchange happens. • These surfaces have to be permeable to O2 and CO2 so that the gases can move easily. What are the features of a gas exchange surface? • Gas exchange surfaces need to have the following features: • Thin tissues for efficient diffusion of gases • An efficient transport system close by to deliver and take away gases • Large surface area so that large volumes of gas can diffuse at once • A constant supply of oxygen Do the human lungs also have these features? Each lung is filled with hundreds of millions of tiny air sacs called alveoli. • The surface of the alveoli is the gas exchange surface. • • O2 diffuses into the blood and CO2 diffuses out. Capillary beds cover the alveoli to deliver a constant supply of blood. • The walls of the alveoli and capillaries are both only one cell thick. • The total surface area of the alveoli in the lungs is over 100 m2. • The airways of the lungs deliver a constant supply of O2. • What cell types are found in the respiratory system? Air first enters the body through the nose and mouth. • Goblet cells in the nose produce mucus to moisten air and protect against pathogens. • Dust and pathogens that enter the respiratory tract are trapped in mucus. • Tiny, hair-like projections called cilia continuously move with a sweeping motion. • Ciliated cells sweep dust and pathogens towards the throat so it doesn’t block the lungs. • What are the parts of the respiratory system? • From the nose, air passes through the voice box, also called the larynx. • Air then passes through the largest airway, the windpipe or trachea. • Rings of cartilage physically support the trachea • The trachea extends into the thorax, the chest cavity containing the heart and lungs. • The trachea branches off into two smaller passages called bronchi. • Bronchi branch off into many even smaller passages called bronchioles. • Bronchioles branch off into alveoli, the gas exchange surface. What are the parts of the respiratory system? The constant movement of air in and out of the lungs is ventilation. • Movements of muscles and bones cause the lungs to be well ventilated. • The diaphragm is a dome-shaped muscle under the lungs. • What are the parts of the respiratory system? The constant movement of air in and out of the lungs is ventilation. • Movements of muscles and bones cause the lungs to be well ventilated. • The diaphragm is a dome-shaped muscle under the lungs. • The intercostal muscles sit between the ribs surrounding the lungs. • • Internal and external These muscles work together to change the size of the thorax. • Changing the size of the thorax to move air in and out of the lungs is breathing. • How does our body move when we breathe in? • When we breathe in (inspiration), the diaphragm contracts and flattens. • The external intercostal muscles also contract, pulling the ribs upwards and outwards. • Both of these movements cause the volume of the thorax to increase. • Air pressure in the lungs becomes lower than atmospheric air pressure. • Air moves from higher pressure outside to lower pressure inside the lungs. • Air flows through the trachea and bronchi into the alveoli. How does our body move when we breathe in? • The diaphragm and the intercostal muscles relax to cause breathing out (expiration). • When the diaphragm relaxes, it takes on its normal dome-shape. • When the intercostal muscles relax, the rib cage moves back down and inwards. • The volume of the thorax decreases, causing the air pressure in the lungs to increase. • The air pressure in the lungs is higher than atmospheric air pressure. • When coughing or exercising, the internal intercostals contract to force air out. Gas exchange at the alveolus • When inspired (breathed in) air reaches the alveoli (air sacs) it contains a lot of oxygen. • Oxygen dissolves in the water lining each alveolus. • It then diffuses through the wall of the alveolus and through the capillary wall into the blood. • Although this involves diffusing through two cells, the distance is very small. Gas exchange at the alveolus • Each alveolus has a network of capillaries around it. • Oxygen molecules from the alveolus diffuse into the red blood cells and combine with haemoglobin. • The blood cells can then transport this oxygen to the body tissues. Gas exchange at the alveolus • There is a lot of carbon dioxide in the capillary. • It has been carried there from the respiring tissues in the blood plasma. • It diffuses in the opposite direction, through the capillary wall across the alveolar wall into the space inside the alveolus. • From here it is breathed out. Gas exchange at the alveolus • Alveoli are surrounded by elastic tissue. • This stretches when you breathe in and recoils when you breathe out to help remove air from the lungs. • The air we breathe out is saturated with water vapour that has evaporated from the moist walls of the alveoli. What’s the difference between inspired and expired air? As we breathe in, air is drawn into the tube on the left. • As we breathe out, air flows into the tube on the right. • What gas in the air would react with limewater to form a precipitate? • Carbon dioxide (CO2) in the air would react to form a precipitate. • Which air contains more CO2, the air you breathe in or the air you breathe out? • What’s the difference between inspired and expired air? • Which tube will contain more precipitate after breathing through the tubes? • Your body uses O2 and makes CO2 in the process of aerobic respiration. • Oxygen content in inspired air is higher than oxygen content in expired air. • Carbon dioxide content in inspired air is lower than carbon dioxide content in expired air. How does exercise affect the breathing rate? • When you exercise vigorously, your muscles quickly use up oxygen for aerobic respiration. • The more your muscles work, the more oxygen they need. You breathe more quickly. • Your lungs can’t take in oxygen quickly enough to supply your muscles adequately. • Muscles in your legs would need more energy than they can get with just aerobic respiration. • To get the extra energy they need, your muscles will also use anaerobic respiration. • Both forms of respiration are used in your muscles at the same time. • The product of respiration in human cells is lactic acid. How does exercise affect the breathing rate? • As you exercise, lactic acid collects in your muscles and blood. • Your body needs to eliminate this lactic acid using aerobic respiration in the liver. • By using anaerobic respiration for energy in your muscles, you built up an oxygen debt. • Your cells “bought” energy that they needed immediately with oxygen they would have later. • The debt goes away as your cells “pay” with oxygen to get rid of the lactic acid. • Your breathing and heartrate stay elevated after exercise until the oxygen debt is paid off. How does exercise affect the breathing rate? • When lactic acid or CO2 build up in the blood, they lower the pH. • When the brain detects a blood pH that is too low, it causes respiratory muscles to contract. • The diaphragm and intercostal muscles contract more often and with more force. • The rate and depth of breathing increases to inspire more O2 and expire more CO2. • More O2 means more aerobic respiration or lactic acid metabolism. • Less CO2 means less carbonic acid in the blood, keeping blood pH to normal.