Flow family anesthesia machines - competitor comparison Focus on ventilation, vaporizers, AGC and RM Flow-i/e vs • Dräger Perseus A500 • Dräger Zeus • GE Aisys CS2 • Mindray A9 MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e - Version 00.9 Comparables Flow-i/Flow-e Dräger Perseus A500 GE Aisys CS2 Dräger Zeus Mindray A9 GENERAL PATIENT TYPE Adult, pediatric, neo Adult, pediatric, neo Adult, pediatric, neo Adult, pediatric, neo Adult, pediatric, neo CONFIGURATION Mobile, ceiling Mobile, ceiling Mobile, ceiling Mobile, ceiling Mobile, ceiling Flow-e: central brake (four wheels) Flow-i: individual brakes Central brake (two wheels) Central brake (two wheels) Central brake (two wheels) Central brake (two wheels) WEIGHT OF ANESTHESIA MACHINE (KG) C20: 138 C30: 138 C:40 138 Flow-e: 164 168 160 180 161 CONTROL SCREEN 15 inches 15 inches 15 inches 20 inches 18,5 inches BATTERY BACKUP 90 min 30 min minimum with monitor 30 min minimum with monitor At least 30 minutes; up to 90 minutes, depending on the ventilation parameters. 90 min MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e - Version 00.9 3 Comparables Flow-i/Flow-e Dräger Perseus A500 GE Aisys CS2 Dräger Zeus Mindray A9 VENTILATOR VENTILATOR TYPE Servo gas modules with volume reflector Digitally controlled gas modules in combination with ascending bellows (bag-inbottle) Turbine (Turbovent 2) with manual bag as gas reservoir Turbine (Turbovent 2) with manual bag as gas reservoir Gas modules with volume exchanger SYSTEM VOLUME (L) 2.8 incl absorber 3,5 incl absorber and bag 4,7 (auto) 4,4 (man) 2 3.35 mechanical ventilation 3.45 manual ventilation (including 1.5 l CO2 absorber) VENTILATION MODES Manual/spontaneous, AFGO, VCV, PCV, SIMV-VC, SIMV-PC, PSVPro, PCV- Manual/spontaneous with optional adjustable VCV, PCV, PRVC, SIMV, apnea VG, CPAP/PSV, SIMV PCV-VG CPAP, pressure control (CMV, SMV+/PS), mute, heart lung mode/cardiac volume control (CMV, CMV/AF/PS); optional bypass mode, inspiratory/ pressure support (CPAP/pressure support), expiratory hold, PSV pressure control (APRV), external fresh gas outlet (electronic gas mixer only) Manual/spontaneous with adjustable CPAP, Manual/Spontaneous, Bypass, VCV with PLV pressure control (CMV, SIMV+, SIMV+/PS), function; PCV, PCV-VG, CPAP, PS with volume control (CMV, CMV/AF, SIMV/AF, backup, SIMV-VC, SIMV-PC, APRV, AMV, SIMV/AF/PS), pressure support consisting of High flow nasal cannula CPAP/pressure support; optional external fresh gas outlet; Smart Ventilation Control FRESH GAS FLOW 0.1-20 l/min 0.2-15 l/min 0.2-15 l/min TIDAL VALUME RANGE (ML) 20–2000, 5 ml in PC 20–1500, 5 ml in PC 20–2000 20-1500 10-1500 (5 ml in PC) PRESSSURE (CMH2O) PEEP RANGE (CMH2O) 0-120 0–50 12-100 Off, 4–30 7-80 Off, 2–35 8-70 Off, 3–35 5-90 0-50 ACTIVE INSPIRED HYPOXIC GUARD O2Guard® Nothing similar Nothing similar Nothing similar Nothing similar APL TYPE & VALVE RANGE (CMH2O) Electronically controlled, SP80 Mechanical Mechanical Mechanical Mechanical NON-CONSUMABLE FLOW SENSORS Yes, Ultrasonic No, Variable orifice No, Hot-wire No, Hot-wire No, Variable orifice 4 0, 0,2-20 l/min MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e Version 00.9 Comparables Flow-i/Flow-e GE Aisys CS2 Dräger Perseus A500 Dräger Zeus Mindray A9 VAPORIZER TYPE Electronic injector Electronic vaporizer – Aladin2 cassette Mechanical flow over with optical reading, Vapor 2000 & 3000 DIVA – direct injection of volatile agents module Electronic injector – Mindray specific NUMBER OF ACTIVE SLOTS 2 1 2-3 2 2 VAPORIZER WEIGHT KG 3,2 full 2,8 7-9 kg 5 kg empty 3,5 POSSIBILITY TO FILL DURING USE Yes No, must be undocked Yes Yes, but it needs to be flushed before. Flush time for sevo appr 1 min Yes FILLING VOLUME (ML) 300 (more than a regular 250 ml bottle) 200 ml for sevoflurane and isoflurane 240 ml for desflurane 300 315 320 HEATING TIME FOR DESFLURANE None None 5–6 minutes for D-Vapor 2 minutes heating for all vaporizers None MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e - Version 00.9 5 Comparables Flow-i/Flow-e GE Aisys CS2 AUTOMATIC GAS DELIVERY MODE AGC (automatic gas control) Et Control (end tidal control) TARGET VALUES The control is made by setting FIO2 and EtAA. Setting the FIO2 is the gold standard. PRE-SETTING Dräger Perseus A500 Mindray A9 TCA (target controlled anesthesia) ACA (automatic controlled anesthesia) The control is made by setting EtO2 and EtAA thus the user has no real control of what the FDO2 is. The control is made by setting FIO2 and EtAA. The control is made by setting FIO2 and EtAA. Possible to preset AGC values in advance thus you can easily activate it when patient is ready for AGC. Not possible to preset agent or FIO2 values Not possible to preset agent or FIO2 values Not possible to preset agent or FIO2 values SETTING OF SPEED Different speeds during induction and emergence can be set. Reduces risk for hemodynamic instability. Not possible. Not having the option of speed settings could cause adverse events eg. hemodynamic instability in some patient groups Not possible. Not having the option of speed settings could cause adverse events eg. hemodynamic instability in some patient groups Not possible. Not having the option of speed settings could cause adverse events eg. hemodynamic instability in some patient groups PREDICTION Predicts the time to reach set target value. Useful function when planning the anesthesia. Not possible to predict the time to reach the target. You must rely on your own knowledge about time to reach target. Not possible to predict the time to reach the target. You must rely on your own knowledge about time to reach target Not possible to predict the time to reach the target. You must rely on your own knowledge about time to reach target AGENT SWITCHING WITH ACTIVE VAPORIZERS Yes, possible. Not possible, need to deactivate the vaporizer before switching to another agent. Previous vapor needs to be washed out before next can be introduced which is costly and time consuming. The manufacturer recommends exiting End-tidal Control mode before changing the anesthetic. Not possible. If you happen to mix gases the user must switch to fresh gas mode until the second gas is washed out. Do not switch to TCA mode for at least 15 minutes. Yes, possile but warning for mixed agent FRESH GAS FLOW Lowest possible is 0,1 L/min which is important for the overall agent consumption. Lowest possible is 0,5 L/min. 0 l/min 0.2 l/min CONSUMABLES No No No Yes, galvanic O2-cell MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e - Version 00.9 6 NOT EXISTING Dräger Zeus Comparables Flow-i/Flow-e LUNG RECRUITMENT Auto RM (Recruitment Maneuver) Vital Capacity One-step recruitment One-step recruitment One-step recruitment • Automatic stepwise RM: a configurable pressure step is applied for a time period • The Vital Capacity procedure automates the manual bag ‘squeeze and hold’. • Automates the manual bag ‘squeeze and hold’. • Automates the manual bag ‘squeeze and hold’. • Automates the manual bag ‘squeeze and hold’. • PEEP can be programmed at the end of the procedure. • PEEP can be programmed at the end of the procedure. • PEEP can be programmed at the end of the procedure to help sustain an open lung. PEEP can be programmed at the end of the procedure. • • PEEP can be programmed at the end of the procedure. • Not a recommended procedure by experts - leads to more hemodynamic compromise and microscopic and biochemical signs of lung injury due to over-distension. • Switches back to the previously set ventilation. • Switches back to the previously set ventilation. • Not a recommended procedure by experts. • Not a recommended procedure by experts. • Not a recommended procedure by experts. • • • SAFE due to stepwise increase in pressure - Less hemodynamic compromise for the patient. VISUALISATION - a real time monitoring of ongoing RM and "Time to target" (the time taken by the recruitment maneuver) helps the workflow in the ORthe user can plan the anesthesia in an efficient manner. EASY - The user can start RM with just one touch. RM trends • • 7 Real-time monitoring that will allow the user to follow the changes in lung mechanics during lung recruitment procedures. EFFECTIVE - graphical breathby-breath presentation of EIP (End Expiratory Pressure), PEEP and Cdyn. - the user can easily assess compliance changes in relation to PEEP changes. • Breath count function - helps the user perform RM manually • Possible to save monitored parameters during a RM (EIP, PEEP, Cdyn) with a time stamp GE Aisys CS2 Perseus A500 Dräger Zeus Cycling • • • Programmable steps allow for increasing and decreasing PEEP levels during mechanical ventilation. Doesn’t show the ongoing RM graphically and compliance measurements in relation to PEEP and PEAK pressures. Not user friendly - it is confusing and it takes long time to configure a RM since it demands a lot of interaction from the user Compliance trending • Provides compliance measurements, but doesn't show the corresponding PEEP and PEAK pressures. Therefore it is difficult to assess compliance changes in relation to PEEP changes. Multi-step recruitment Multi-step recruitment • Programmable steps allow for increasing and decreasing PEEP levels during mechanical ventilation. • • Max inspiratory pressure and max PEEP are set • Max inspiratory pressure and max PEEP are set • Automatic decremental phase • Automatic decremental phase • Reminder: time since last RM • Reminder: time since last RM Programmable steps allow for increasing and decreasing PEEP levels during mechanical ventilation. Compliance trending Compliance trending • Provides compliance trending graphically and with arrows • Provides compliance trending graphically and with arrows • Arrows shows direction of pressure and PEEP • Arrows shows direction of pressure and PEEP Mindray A9 Multi-step recruitment • Programmable steps allow for increasing and decreasing PEEP levels during mechanical ventilation. • Delta pressure, PEEP, Breaths, I:E,rate and PEEP on exit are set Compliance trending • Provides compliance trending graphically • Has no breath count function - the user has to count breaths in every step if RM is performed manually. • Not possible to save monitored parameters (EIP, PEEP, Cdyn) during a RM with a time stamp. MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e Version 00.9 Flow-c vs • GE CS 650 • GE CS 750 • Dräger Atlan • Mindray A7 MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e - Version 00.9 Comparables Flow-c GE CS650 GE CS750 Dräger Atlan Mindray A7 GENERAL PATIENT TYPE Adult, pediatric, neo Adult, pediatric, neo Adult, pediatric, neo Adult, pediatric, neo Adult, pediatric, neo CONFIGURATION Mobile, ceiling Mobile, ceiling, wall Mobile, ceiling, wall Mobile, ceiling, wall Mobile, ceiling Central brake (four wheels) Central brake (two wheels) Central brake (two wheels) Central brake (two wheels) Central brake (two wheels) WEIGHT OF ANESTHESIA MACHINE (KG) 134 145 145 147 (without vaporizers) 118 (wall mount version) 160 CONTROL SCREEN 15 inches 12 inches 15 inches 15 inches, fixed 15 inches, fixed BATTERY BACKUP 90 min 30 min minimum with monitor 30 min minimum with monitor At least 30 minutes; up to 90 minutes, depending on the ventilation parameters. 90 min MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e - Version 00.9 9 Comparables Flow-c GE CS650 GE CS750 Dräger Atlan Mindray A7 VENTILATOR VENTILATOR TYPE Servo gas modules with volume reflector Digitally controlled gas modules in combination with ascending bellows (bag-inbottle) Digitally controlled gas modules in combination with ascending bellows (bag-inbottle) Piston Digitally controlled gas modules in combination with ascending bellows (bagin-bottle) SYSTEM VOLUME (L) 2.8 incl absorber 3,5 incl absorber and bag 3,5 incl absorber and bag 4,7 (auto) 4,4 (man) 2,85 (auto) 1,8 (man) VENTILATION MODES VC, PC, PS, PRVC, SIMV(PC), SIMV(VC), Manual/Spontaneous, AFGO VC, PC, PCV-VG, SIMV PCV-VG, PSV, CPAP+PSV, Manual/Spontaneous VC, PC, PCV-VG, SIMV PCV-VG, PSV, CPAP+PSV, Manual/Spontaneous FRESH GAS FLOW 0.1 -20 l/min 0.1-15 l/min 0.1-15 l/min 0.2-15 l/min 0.2-15 l/min TIDAL VOLUME RANGE (ML) 20–2000, 5 ml in PC 20–2000, 5 ml in PC 20–2000, 5 ml in PC 5-1500 20-1500 PEEP RANGE (CMH2O) 0–50 Off, 4–30 Off, 4–30 Off, 2–35 Off, 3–30 ACTIVE INSPIRED HYPOXIC GUARD O2Guard® Nothing similar Nothing similar Nothing similar Nothing similar APL TYPE & VALVE RANGE (CMH2O) Electronically controlled, SP80 Mechanical Mechanical Mechanical Mechanical NON-CONSUMABLE FLOW SENSORS Yes, Ultrasonic No, Variable orifice No, Variable orifice No, hot wire No, Variable orifice 10 Manual/Spontaneous (Man/Spon); volume control (VC-CMV); pressure control (PCCMV) Manual/spontaneous, VCV, PCV, PVC-VG, SIMV-VC, SIMV-PC, PS; SIMV-VG, CPAP/PS; APRV MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e Version 00.9 Comparables Flow-c GE CS650 GE CS750 Dräger Atlan Mindray A7 VAPORIZER TYPE Electronic injector Mechanical variable bypass, Tec 6 Plus and/or Tec 7 Mechanical bypass, Tec 6 Plus and/or Tec 7 Mechanical variable bypass with optical reading, Vapor 2000 & 3000 Mechanical variable bypass, V60 NUMBER OF ACTIVE SLOTS 1 2 2 1-3 2 VAPORIZER WEIGHT KG 3,2 full 7-10 7-10 7-9 8 POSSIBILITY TO FILL DURING USE Yes Yes Yes Yes Yes FILLING VOLUME (ML) 300 (more than a regular 250 ml bottle) 300 ml but only 225 ml when refilling due to that 75 ml is reatined by the wick system 300 ml but only 225 ml when refilling due to that 75 ml is reatined by the wick system 300 360 HEATING TIME FOR DESFLURANE None Yes Yes 5–6 minutes for D-Vapor Yes MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e - Version 00.9 11 Comparables Flow-c AUTOMATIC GAS DELIVERY MODE AGC (automatic gas control) TARGET VALUES The control is made by setting FIO2 and EtAA. Setting the FIO2 is the gold standard. PRE-SETTING Possible to preset AGC values in advance thus you can easily activate it when patient is ready for AGC. SETTING OF SPEED Different speeds during induction and emergence can be set. Reduces risk for hemodynamic instability. PREDICTION Predicts the time to reach set target value. Useful function when planning the anesthesia. AGENT SWITCHING WITH ACTIVE VAPORIZERS Yes, possible. FRESH GAS FLOW Lowest possible is 0,1 L/min which is important for the overall agent consumption. GE CS650 NOT EXISTING MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e - Version 00.9 12 GE CS750 NOT EXISTING Dräger Atlan NOT EXISTING Mindray A7 NOT EXISTING Comparables Flow-c LUNG RECRUITMENT Auto RM (Recruitment Maneuver) Vital Capacity Vital Capacity • Automatic stepwise RM: a configurable pressure step is applied for a time period • The Vital Capacity procedure automates the manual bag ‘squeeze and hold’. • • • PEEP can be programmed at the end of the procedure to help sustain an open lung. PEEP can be programmed at the end of the procedure. The Vital Capacity procedure automates the manual bag ‘squeeze and hold’. • PEEP can be programmed at the end of the procedure. • Not a recommended procedure by experts - leads to more hemodynamic compromise and microscopic and biochemical signs of lung injury due to over-distension. • • • SAFE due to stepwise increase in pressure - Less hemodynamic compromise for the patient. VISUALISATION - a real time monitoring of ongoing RM and "Time to target" (the time taken by the recruitment maneuver) helps the workflow in the ORthe user can plan the anesthesia in an efficient manner. EASY - The user can start RM with just one touch. RM trends • • 13 Real-time monitoring that will allow the user to follow the changes in lung mechanics during lung recruitment procedures. EFFECTIVE - graphical breathby-breath presentation of EIP (End Expiratory Pressure), PEEP and Cdyn. - the user can easily assess compliance changes in relation to PEEP changes. • Breath count function - helps the user perform RM manually • Possible to save monitored parameters during a RM (EIP, PEEP, Cdyn) with a time stamp GE CS650 • Not a recommended procedure by experts - leads to more hemodynamic compromise and microscopic and biochemical signs of lung injury due to over-distension. GE CS750 Cycling • • • Programmable steps allow for increasing and decreasing PEEP levels during mechanical ventilation. Doesn’t show the ongoing RM graphically and compliance measurements in relation to PEEP and PEAK pressures. Not user friendly - it is confusing and it takes long time to configure a RM since it demands a lot of interaction from the user Compliance trending • Provides compliance measurements, but doesn't show the corresponding PEEP and PEAK pressures. Therefore it is difficult to assess compliance changes in relation to PEEP changes. • Has no breath count function - the user has to count breaths in every step if RM is performed manually. • Not possible to save monitored parameters (EIP, PEEP, Cdyn) during a RM with a time stamp. • • NOT EXISTING Mindray A7 One-step recruitment • Automates the manual bag ‘squeeze and hold’. • PEEP can be programmed at the end of the procedure. • Not a recommended procedure by experts. Multi-step recruitment • Programmable steps allow for increasing and decreasing PEEP levels during mechanical ventilation. Programmable steps allow for increasing and decreasing PEEP levels during mechanical ventilation. • Delta pressure, PEEP, Breaths, I:E,rate and PEEP on exit are set Doesn’t show the ongoing RM graphically and compliance measurements in relation to PEEP and PEAK pressures. Compliance trending Cycling • Dräger Atlan Not user friendly - it is confusing and it takes long time to configure a RM since it demands a lot of interaction from the user • Provides compliance trending graphically Compliance trending • Provides compliance measurements, but doesn't show the corresponding PEEP and PEAK pressures. Therefore it is difficult to assess compliance changes in relation to PEEP changes. • Has no breath count function - the user has to count breaths in every step if RM is performed manually. • Not possible to save monitored parameters (EIP, PEEP, Cdyn) during a RM with a time stamp. MX-8620 - Competitor comparison - AGC & RM launch for Flow -c and-e Version 00.9
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