GENETICS
GENERAL INFORMATION
In English: Genetics
Course Title
In Vietnamese: Di truyền học
BIO1.002
Credit points (ECTS)
Course Code
Requirement
Prerequisites
Time Commitment
3
Basic cell biology, basic biochemistry, mathematics
(probability)
Lecture
20 hrs
Exercises
10 hrs
Practical
4 hrs
Total
34 hrs
DESCRIPTION
CO2
Students will acquire basic knowledge in DNA structure and
function
Students will acquire basic knowledge in mechanisms of RNA
and protein synthesis
CO3
Students will acquire basic knowledge in gene inheritance
CO4
Students will acquire basic knowledge in genetic differences
between individuals
CO5
Students will acquire basic knowledge in genetic differences
between species
CO6
Students will acquire basic knowledge in biotechnology
applications
CO7
Students will acquire basic knowledge in introduction to
epigenetics
CO8
In addition, students will be able to solve simple problems
regarding the genetic code, protein synthesis and gene
inheritance
CLO1
Comprehensive, detailed understanding of the chemical basis of
heredity and genetic methodology.
CO1
Course
Objectives
(CO)
Course
learning
outcomes
(CLO)
CLO2
Understanding the role of genetic mechanisms in evolution.
Understanding the role of genetic technologies in industries
CLO3
related to biotechnology
Course
description
This course is an introduction to genetics for students in the fields of
biotechnology and pharmacy
Biology. Campbell & Reece. 8th Ed. Pearson
Textbooks
Introduction to genetic analysis. Griffiths et al. 9th Ed. Freeman.
ASSESSMENT/EVALUATION
Percentage (%)
Attendance/Attitud
e
20
Tutor
20
Final exams
60
Type
MCQ (1.5 hours)
MAIN CONTENTS
No.
1
2
3
4
5
Contents
Introduction to the genetic revolution: from
Mendel to genome sequencing, a historical
perspective
DNA:
-
DNA structure, chromatin structure
Chromosomes and karyotype
Definition of the gene and the genome
DNA replication in prokaryotes and
eukaryotes
From genes to proteins:
- The genetic code
- RNA synthesis (transcription)
- Protein synthesis (translation)
- Control of gene expression
Genetic variations:
- Metagenomics: gene and genome
structure in bacteria, plants and
animals, genetic differences and
similarities between species
- Genetic variations, mutations and
polymorphisms
- Somatic gene variations and cancer
Inheritance (part I):
Contact hours
Lecture
Exercise
2
3
2
3
2
3
2
2
Practical
-
Reproduction of cells and organisms,
meiosis
Mendel laws
Inheritance (part II): particular cases
6
7
8
-
Sex chromosomes
Linkage (Morgan law)
Mitochondrial inheritance
Introduction to population genetics: HardyWeinberg law
Epigenetics:
-
DNA methylation
Chromatin regulation
2
2
1
2
2
An introduction to gene technologies:
9
10
DNA sequencing
Bioinformatics: sequence comparison
using BLAST, databases
Polymerase Chain Reaction
Artificial genes and protein production
Transgenesis in animals and plants
Conclusion and discussion
1
1
4