See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/366593791 Return to Sport After Total Shoulder Arthroplasty and Hemiarthroplasty: A Systematic Review Article in Sports Medicine and Arthroscopy Review · December 2022 DOI: 10.1097/JSA.0000000000000306 CITATIONS READS 3 104 7 authors, including: Edoardo Franceschetti Pietro Gregori Campus Bio-Medico University Campus Bio-Medico University 77 PUBLICATIONS 1,333 CITATIONS 30 PUBLICATIONS 140 CITATIONS SEE PROFILE SEE PROFILE Edoardo Giovannetti de Sanctis Michele Paciotti Institut Universitaire Locomoteur & Sport (IULS) - Hôpital Pasteur II Campus Bio-Medico University 52 PUBLICATIONS 383 CITATIONS 19 PUBLICATIONS 485 CITATIONS SEE PROFILE All content following this page was uploaded by Nicola Maffulli on 18 November 2024. The user has requested enhancement of the downloaded file. SEE PROFILE REVIEW ARTICLE Return to Sport After Total Shoulder Arthroplasty and Hemiarthroplasty: A Systematic Review Edoardo Franceschetti, MD,* Pietro Gregori, MD,* Edoardo Giovannetti de Sanctis, MD,† Alessio Palumbo, MD,* Michele Paciotti, MD,* Nicola Maffulli, MD, MS, PhD, FRCP, FRCS,‡§∥ and Francesco Franceschi, MD¶ Purpose: One of the most frequent concerns of the increasing number of patients undergoing shoulder arthroplasty is the possibility to resume sport after surgery. This systematic review determined the rate of return to sport after total shoulder arthroplasty (TSA) and hemiarthroplasty (HA). Materials and Methods: The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed to perform this systematic review. A systematic electronic search was performed using the PubMed (MEDLINE), EMBASE, and Cochrane Library databases. All the studies analyzing the rates of reverse shoulder arthroplasties were pooled; data were extracted and statistically analyzed. Only studies with at least 10 adult patients recruited were considered. All studies had to relate return to sport after TSA or HA. Results: A total of 76 studies were included for a total of 694 patients. The mean age and average follow-up were, respectively, 64.5 years (range: 24 to 92 y) and 4.5 years (range: 0.5 to 12 y). The mean rate of return to sport ranged from 49.3% to 96.4%. The mean time to resume sports was 8.1 months. The overall rate of return to sport after the procedures, according to a random effect model, was 83%. The mean level of sports at the time of the survey was worsened in 9.4% ( ± 2.82%), improved or reported from good to excellent in 55.6% ( ± 13.6%), and did not change in 40% ( ± 1.4) of patients. function. Over the last decade, indications for this type of surgery have been expanded, resulting in a marked increase of procedures performed every year.1 Even though pain and limited function of the shoulder remain the main reasons why patient decide to undergo these procedures, the expanded indications have led to a larger population of young and active patients who place an increasing interest on the ability to resume activities that were difficult or not possible before replacement surgery.2,3 The abilities to resume sport after total hip or knee replacement4,5 are well documented. On the contrary, studies focusing on returning to sport after TSA and HA are limited and do not seem to clarify doubts of patients desiring a reliable prediction on the probability of resuming their activities after surgery. Also, the perspective could be extremely divergent given the different physical activities undertaken in the United States and Europe.6 This systematic review determined the rate of return to sport after TSA and HA, providing surgeons reliable information to make patients aware about the probability of resuming sport following the procedures. MATERIALS AND METHODS Conclusions: On the basis of current available data, return to sports after TSA and HA is possible and is highly frequent. The subjective level of practice does not change or improve in most patients. More studies and better designed trials are needed to enrich the evidence on specific sport recovery after the procedure. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines have been utilized to carry out this systematic review.7 The PRISMA statement is composed of a 27-item checklist relating to review contents and a 4-phase flow chart of the study selection process. Key Words: shoulder, total shoulder arthroplasty, arthroplasty, hemiarthroplasty Eligibility Criteria (Sports Med Arthrosc Rev 2021;00:000–000) T otal shoulder arthroplasty (TSA) and hemiarthroplasty (HA) are well-established treatments for patients with glenohumeral osteoarthritis with residual rotator cuff From the *Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University; †Department of Orthopaedics and Traumatology, Agostino Gemelli Hospital, Catholic University; ¶Department of Orthopaedic and Trauma Surgery, San Pietro Fatebenefratelli Hospital, Rome; ‡Department of Musculoskeletal Disorders, Salerno, Italy; §Centre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, Mile End Hospital, London; and ∥School of Pharmacy and Bioengineering, Keele University School of Medicine, Stoke on Trent, England. Disclosure: The authors declare no conflict of interest. Reprints: Nicola Maffulli, MD, MS, PhD, FRCP, FRCS (Orth), Department of Musculoskeletal Disorders, Via Salvador Allende, 43, Baronissi SA, Salerno 84081, Italy. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. Sports Med Arthrosc Rev Volume 00, Number 00, ’’ 2021 Studies published in English, Italian, French, Spanish, and German were eligible for inclusion. Only peer-reviewed journals were considered, and randomized controlled trials, prospective and retrospective comparative studies and case series (CS) were included. Exclusion criteria were reviews of the literature, expert opinions, and studies that did not evaluate return to play. The eligibility criteria were studies with at least 10 adult participants recruited. All studies had to relate to return to sport after TSA and HA. Information Sources and Search An electronic systematic search of CINAHL, EMBASE, PubMed, and the Cochrane Central Registry of Controlled Trials was carried out by 2 reviewers (P.G. and E.F.), to identify eligible studies. Interrater reliability for study eligibility was measured using the κ statistic. A κ of 0 to 0.2 represents slight agreement, 0.21 to 0.40 fair agreement, 0.41 to 0.60 moderate agreement, and 0.61 to 0.80 substantial agreement. A value > 0.80 is considered almost perfect agreement, according to the guidelines of Landis and www.sportsmedarthro.com | 1 Copyright r 2021 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited. Sports Med Arthrosc Rev Volume 00, Number 00, ’’ 2021 Franceschetti et al TABLE 1. Study Details References Level of Evidence Study Type Year of Publication Follow-up [Mean (Range)] MINORS IV IV IV IV IV IV IV III IV IV IV CS CS CS CS CS CS CS CS CS CS CS 1998 1998 2008 2010 2014 2015 2015 2016 2017 2017 2018 4.5 (2-10.6) 4.2 (0.5-8.2) 3.7 (2-9.4) 2.8 (1.3-4.6) 6.2 (2.5-12.6) 5.1 (2-7.5) 3.2 (1.0-7) 5.2 (2-7.5) 5.5 (2.5-12) 5 (2-8.6) 3.7 (2-10) 6/16 6/16 15/24 10/16 9/16 11/16 9/16 17/24 10/16 12/16 11/16 Jensen and Rockwood8 Skutek et al9 McCarty et al10 Schumann et al11 Buhloff et al12 Garcia et al13 Papaliodis et al14 Garcia et al15 Bulhoff et al16 Garcia et al17 Mannava et al18 CS indicates case series; MINORS, Methodological Index for Nonrandomized Studies. Koch. The search was executed on September 28, 2020. The search strings used were: ((Return to sports [MeSH Terms]) AND TSA [MeSH Terms] AND HA [MeSH Terms]); (((TSA [MeSH Terms]) AND Sports [MeSH Terms]) AND surgery) AND outcomes. Study Selection Once the duplicates had been removed, relevant articles from the electronic search were retrieved in full text and evaluated. A manual search of the bibliography of each published study was performed, to find relevant articles that could potentially have been missed. Reviews, systematic reviews, and meta-analyses were also retrieved and read, to broaden the search to include studies that might have been missed. The remaining articles were analyzed by 2 reviewers (P.G. and E.F.), to exclude studies not fulfilling the eligibility criteria. The reviewers were not blinded to the authors, year, and journal of publication. Studies eligible for inclusion were categorized by study type, according to the Oxford Centre for Evidence-Based Medicine (www.cebm.net). The following categories were utilized: case report, randomized controlled trial, and CS. Case reports (reporting data of 10 or fewer patients) were excluded because of low significance. Data Collection Process Two assessors independently extracted data from the eligible studies using a predefined data extraction. For each study, we extracted data concerning the epidemiological characteristics of participants (age, sport, level) and assessment of results (return to sport, mean follow-up, type of sport, time to return to sport, level after surgery). Data were analyzed using the R software (2020; R Core Team). The primary end point was the rate of resuming sport after shoulder replacement surgery. The I2 index was used to measure the heterogeneity of results within the included studies. Substantial heterogeneity was defined as I2 > 75%. The mean rate for resuming sport was calculated with a 95% confidence interval. Results were displayed using a forest plot (Fig. 3). Quality of the Studies The quality of included studies was evaluated using the MINORS (Methodological Index for Nonrandomized Studies) score. The following domains were assessed: a clearly stated aim, inclusion of consecutive patients, prospective data collection, end points appropriate to the aim of the study, unbiased assessment of study end points, follow-up period appropriate to the aim of the study, loss to follow-up of <5%, prospective calculation of the study size, adequate control group, contemporary group, baseline group equivalence, and adequate statistical analysis (Table 1). Two authors (P.G. and E.F.) performed this evaluation, which included a discussion to reach a consensus in case of disagreement. We also analyzed the quality of the studies over the years through a graphic representation (Fig. 2). RESULTS A total of 76 studies were identified in the electronic search; of these, 11 were eligible for inclusion in this systematic review. No further studies were identified as relevant through the manual search. All the individuated studies were retrospective CS (interrater agreement κ value = 0.79). The study selection process is shown in Figure 1. Study details are summarized in Table 1. The main indication for the procedures was primary shoulder osteoarthritis. Other indications included proximal humerus fracture, rheumatoid arthritis, avascular necrosis, posttraumatic arthritis, postinstability arthritis, and rotator cuff arthropathy. The most common reported sports were golf (9 studies), swimming (8 studies), and tennis (8 studies). None of these studies included professional athletes. A total of 694 patients were included in the 11 studies. The mean age, which was calculated in only 8 of the selected studies, was 64.5 years (range: 24 to 92 y), with an average follow-up of 4.5 years (range: 0.5 to 12 y) (Table 2). Methodological Quality The average value was 9.3 on the MINORS scale, although 2 comparative studies were evaluated on a 24-point scale and not on a 16-point scale. These studies had a MINORS score of 16 and 17. Also, there was progressive improvement in the quality of studies from 1998 to 2018 (Fig. 2). Return to Sport The mean rate of return to sport ranged from 49.3% to 96.4%. The mean time for resuming sports was 8.1 months. All the included studies concluded that a return to sport after TSA and HA is possible. The overall rate of return to sport after the procedures, according to the random effect model, was 83% (95% confidence interval: 71%-91%). I2 index was 91% (Fig. 3). In the studies reporting this parameter, the mean level of sports at the time of the survey worsened in 9.4% ( ± 2.82%), improved or reported from good to excellent in 2 | www.sportsmedarthro.com Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. Copyright r 2021 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited. Sports Med Arthrosc Rev Volume 00, Number 00, ’’ 2021 Return to Sport After TSA and HA FIGURE 1. Prisma flowchart of the study selection process. 55.6% ( ± 13.6%), and did not change in 40% ( ± 1.4) of the patients. Two studies15,18 did not distinguish 2 variables (“no change” and “improved”), thus they have been excluded from this calculation. Functional Outcome and Patient Satisfaction The rate of patient satisfaction with surgery was reported in 4 studies13,15,17,18 with a mean of 90.4% ( ± 11.3%). None of the studies reported sport-specific satisfaction. The Visual Analog Scale, or other investigations evaluating pain after surgery, were reported in 5 studies11,13,15,17,18 showing statistically significant improvement in all reported cases. The American shoulder and elbow surgeons score was reported in 4 studies13,15,17,18 with a mean of 82.9% ( ± 7.9%). DISCUSSION TSA and HA have been more extensively performed in recent years for a variety of reasons, most commonly to reduce pain in patients with advanced osteoarthritis and proximal fractures. Patients undergoing total joint arthroplasty increasingly wish to continue to participate in sports and recreational activities following surgery. Over time, in addition to reducing pain, the procedure aims to restore shoulder function and increase patient’s quality of life, including not only daily living but also sporting activities. Commonly, during preoperative and postoperative consultations, surgeons are asked by patients whether they will be allowed to participate in the activities they enjoyed before the onset of shoulder pathology and/or surgery. There is a lack of consensus concerning the recommendations to give patients about resuming sport activities after TSA and HA. This systematic review aimed to evaluate the rate of return to sport after these procedures. The overall return rate to sport averaged > 83%, which suggests that resuming sports after surgery is realistic and frequent. The activity level was investigated through a questionnaire. Most of the studies did not collect all 3 variables “worsened,” “improved,” or “no change.” The ones reporting a worsening of the subjective sports performance had a mean of 9.4%, while the ones analyzing an improvement or full recovery of the same sports level before the onset of osteoarthritis reported a total mean of 95.6%. Even though the quality of the published evidence is low, return to sport is a realistic aim. Our results are in accordance with Liu et al19 who conducted a systematic review and meta-analysis evaluating return to sport after shoulder replacement. The overall return to sport in the TSA group was 92.6% and averaged 71.1% in the HA group. Aim et al,20 in 2017, showed that patients undergoing TSA and HA were still able to return to sport with a slightly higher rate of the ones undergoing reverse shoulder Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. www.sportsmedarthro.com | 3 Copyright r 2021 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited. Sports Played Rate of Return to Sport (%) Level of Sport After Surgery Time to Return to Sport After Surgery (mo) Golf 95.8 NR 4.5 8.3 81 Good to excellent: 61.5% Improved: 71% Types of Shoulder Arthroplasty (N) Age [Mean (Range)] (y) Jensen and Rockwood8 Skutek et al9 24 TSA: 20 HA: 6 HA: 13 53.4 (26.4-78.7) 62 (47-82) Swimming, cycling, dancing, shooting McCarty et al10 75 TSA: 61 HA: 25 65.5 (24-88) Schumann et al11 100 TSA: 155 68.9 (26-92) Buhloff et al12 105 TSA: 105 NR Garcia et al13 79 69 (27.6-97.1) Papaliodis et al14 35 All HA, N: nonreported TSA: 36 Swimming, skiing, softball, tennis, fishing, golf, weight lifting, bowling, hiking, basketball, hunting, dancing, equestrian, Racquetball, Kayaking, sailing, squash, aerobics, snorkeling, darts, baseball, wrestling, sculpting, cycling, handball Swimming, cycling, alpine skiing, fitness, Windsurfing, volleyball, tennis, table tennis, squash, soccer, snowboarding, sailing, Nordic walking, Nordic skiing, jogging, inline skating, ice hockey, horse riding, hiking, gymnastic, golf, classic ballet, bowling, biking, aquafit Swimming, skiing coma bowling, tennis, handball, athletics, volleyball, golf Swimming, skiing, tennis 67.2 (57.2-80.4) Garcia et al15 80 TSA: 40 HA: 40 66 (42-88) Buhloff et al16 29 All HA, N: nonreported NR Garcia et al17 59 TSA: 61 NR Mannava et al18 95 TSA: 112 64 (18-82) References 13 HA indicates hemiarthroplasty; NR, not reported; TSA, total shoulder arthroplasty. 3.6 89 No change: 40.8% 5 57.1 Worsened: 9% 24 49.3 Improved: 50.8% 6.5 Golf 88 8.8 Baseball, basketball, nature sports, golf, fitness sports, swimming, running, cycling, double tennis, softball, single tennis Swimming, tennis, skiing, bowling, athletics, volleyball, handball, golf, other sports not specified Fitness, running, golf, basketball, single tennis, swimming, cycling, double tennis, football, skiing, softball, lacrosse, volleyball, yoga, wrestling, baseball, martial arts, racquetball, hockey, paddle tennis, dancing, cross country, gymnastic Skiing, snowboarding, hockey, golf, biking, tennis, fitness, swimming, hunting, horseback riding, fishing, hiking, running 81.4 Improved: 48% Worsened: 13% No change: 39% No change or improved: 76% 5.5 67 NR NR 96.4 Improved: 47.3% 6.7 93.7 No change or improved: 69.7% Worsened: 6.3% NR Sports Med Arthrosc Rev Volume 00, Number 00, ’’ 2021 Patients (N) Franceschetti et al 4 | www.sportsmedarthro.com Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. Copyright r 2021 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited. TABLE 2. Main Outcome Rates Sports Med Arthrosc Rev Volume 00, Number 00, ’’ 2021 Return to Sport After TSA and HA FIGURE 2. Diagram representing the quality of the study in relation to the year of publication. A positive trend, with increasing quality along ages, is shown. MINORS indicates Methodological Index for Nonrandomized Studies. arthroplasty, a likely consequence of the presence in this group of elderly patients, eccentric shoulder arthritis involving rotator cuff tears, and worse shoulder function with altered natural biomechanics after surgery. Furthermore, the reported scores in all the included studies increased after surgery, which further underlines the benefits of shoulder arthroplasty. A subgroup analysis on the return rate for specific sports could not be conducted given the limited data in the literature. Also, considering the limited number of investigations studying separately the rates of return to sports for the 2 procedures, a separate analysis would not have been reliable. Nevertheless, Garcia et al,15 comparing HA and TSA, demonstrated that TSA led to higher rates of return to sports. The analysis of the quality of the studies revealed an increased quality over the years. Our study had several limitations. The most relevant limitation is the low evidence level of the included studies as most are level IV studies and the low number of studies available on this topic. Moreover, indications for arthroplasty were heterogeneous as were the sports assessed. Finally, lack of a subgroup analysis for the specific sport could produce a high risk of bias. CONCLUSIONS In the vast majority of cases, sport can be resumed with return to the predisease status or an improvement. Further research and well-designed studies should be carried out to FIGURE 3. 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