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AML: Acute Myelogenous Leukemia Overview

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This paper is centered on Acute Myelogenous Leukemia (AML), a disease that develops when
abnormally growing myeloblasts disrupt the generation of normal blood cells. This condition is
associated with symptoms such as excessive bleeding, exhaustion, and vulnerability to diseases due to
poor blood cell formation. AML emanates from gene mutations, such as internal tandem duplications
that interfere with the control of blood cells. It then results in pancytopenia, a condition that is caused
by low levels of all blood products due to an increase in the number of immature blood cells in the bone
marrow. In diagnosing this disorder, Auer rods are used because they reveal the aggressiveness of the
disease. Some of the management models that are used include eradicating immature cells include stem
cell transplantation and using chemotherapy.
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