Adaptiv Biphasic Defibrillation Bi-Phasic vs. Mono-Phasic Technical LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Definition: Termination of lethal heart rhythms by application of a biphasic defibrillation shock Clinical Significance: The first major advance in defibrillation technology in 30 years Improved first shock efficacy as compared to “gold standard” monophasic defibrillation LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . A Brief History Of Defibrillation 1950s and prior • AC defibrillation: Low efficacy, high occurrence of myocardial damage 1960s • Introduction of DC defibrillation: Most devices using a damped sinusoidal defibrillation waveform (Monophasic, Lown, Edmark) • Great improvement in patient outcome; Monophasic DC defibrillation becomes the standard of care 1970s, 1980s • Research continues, but NO IMPROVEMENTS IN THERAPY Late 1990s • Introduction of 3D Biphasic defibrillation technology; Improved first-shock efficacy, emergence of a new standard of care LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Monophasic Defibrillation Characterized by: • Unidirectional current flow • High peak current (>50 amps @ 360 joules) • Short pulse duration (3 – 10 ms) Monophasic Defibrillation C U R R E N T I Peak TIME T10% (3.1 - 9.2 m s) LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Adaptiv Biphasic Defibrillation BTE (Biphasic Truncated Exponential) waveform Characterized by: • Bi-directional current flow • Lower peak voltage (<2200V @ 360 joules) and current • Fast rise and fall times 3D Biphasic Defibrillation C U R R E N T I1 T PHASE 2 4.5 - 5.3 ms TIME T PHASE 1 (6.8 - 7.9 ms) I4 LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Differences In Product Architecture The Adaptiv Biphasic defibrillator uses several components not found in the monophasic model: • Biphasic PCB assembly • Energy storage capacitor Metalized polypropylene 196 uF • Inductive Resistor • High voltage isolation relay LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . How It Works: Review: Monophasic defibrillation • The storage capacitor is charged • The capacitor discharges through the waveshaping inductor and the patient impedance in a single-phase pulse Wav eshaping Inductor + Energy Energy Storage Capacitor Charger Storage Capacitor C u r r e n t Time Monophasic Defibrillator Transfer Relay LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Biphasic Defibrillation: The “H” Bridge The biphasic shock is delivered through a semiconductor bridge • Each element is assigned a map coordinate for identification Two different semiconductor components are used: • SCRs (three in a custom package) • A single Insulated Gate Bipolar Transistor (IGBT) The "H" Bridge Inductive Resistor NW Energy Storage Capacitor NE Custom SCR Package + Bridge Outputs (To Paddles) SW SE IGBT LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Characteristics Of The “H” Bridge Components The SCR • With gate voltage applied, the switch closes – current flows from terminal to terminal • As long as current is flowing, • removing gate drive DOES NOT open the switch The IGBT • With gate voltage applied, the switch closes – current flows from terminal to terminal • Removing gate drive opens the switch Current Flow Gate Driv e Current Flow Gate Driv e LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . The Biphasic Shock - 1st Phase Begins NW and SE switches close • Under control of the biphasic PCB processor • Current flows for the 1st phase Biphasic Discharge Ind uctive Resistor NW Energy Sto rage Cap acitor NE + SW SE C U R R E N T 0V TIME LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . The Biphasic Shock – 1st Phase Ends SE switch is opened • Interrupts current flow • NW switch opens spontaneously when current flow stops Charge remains on storage capacitor Biphasic Discharge Ind uctive Resistor NW Energy Sto rage Cap acitor NE + SW SE C U R R E N T 0V TIME LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . The Biphasic Shock – Interphase Time All switches open for 500 uS • Current flow settles to zero Biphasic Discharge Ind uctive Resistor NW Energy Sto rage Cap acitor NE + SW SE C U R R E N T 0V TIME LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . The Biphasic Shock – 2nd Phase Begins NE and SW switches close • Current flows in the opposite direction • 2nd phase is created Biphasic Discharge Ind uctive Resistor NW Energy Sto rage Cap acitor NE + SW SE C U R R E N T 0V TIME LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . The Biphasic Shock – 2nd Phase Ends All switches close • Any remaining charge is shorted out through the A14 Inductive Resistor Biphasic Discharge Ind uctive Resistor NW Energy Sto rage Cap acitor NE + SW SE C U R R E N T 0V TIME LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . The Biphasic Shock – Energy Dump To dump unwanted energy, all switches close • The A14 Inductive Resistor acts as the dump resistor Indu ctive Resistor NW Energy Storage Cap acitor NE + SW SE LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Components Continued . . Inductive Resistor Less resistance and inductance than monophasic waveshaping inductor • 5 ohms, 700uH vs. 10.8 ohms, 21mH Performs Several Critical Functions Limits current during shorted paddles discharge Limits current during internal dump (acts as dump resistor) Truncates 2nd phase (absorbs remaining energy) LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Adaptive Defibrillation The Adaptiv Biphasic waveform adapts to the impedance of the patient • Optimizes the energy delivered Three variable parameters: • Peak voltage • Duration • Tilt Adaptations are based on patient impedance measurement LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Which waveform is right for you??? LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Paddles Patient Impedance Measurement Based on voltage measurements taken during defibrillation • 1st measurement - peak voltage of 1st phase • 2nd measurement – after 4.5 ms • Delta-V calculation; provides patient impedance Impedance Measurement V1 V2 4.5 mS LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Patient Impedance Measurement Continued . . . 1st phase duration is adjustable • As a function of measured patient impedance • “Tilt” changes as a by-product of the duration adjustment Compensates the shock for the patient’s impedance Impedance Measurement 1st Phase Duration Adj usts LIFEPAK Education. Copyright Medtronic Corporation, September 2002 Adaptiv Biphasic Defibrillation Continued . . . Two Subsequent Measurements Are Taken End of 1st phase, end of 2nd phase • 2nd phase duration always 2/3 of first phase Used to sense open or shorted discharge • “Energy Fault” message is displayed Impedance Measurement V3 V4 LIFEPAK Education. Copyright Medtronic Corporation, September 2002