RESPIRATORY 2 REGIONS 1. Conducting passages a. Trachea b. Primary bronchi c. Secondary bronchi d. Conducting bronchi 2. Respiratory passages a. Respiratory bronchioles b. Alveoli TRACHEA 1. Trachealis muscle – smooth 2. mucosa a. E: pseudostratified columnar b. Basement membrane c. Lamina propria 3. Submucosa a. Glands – seromucinous glands 4. C-shaped hyaline cartilage BRONCHI 1. Epithelium a. Primary – psedotratified columnar b. Secondary: cilitated simple columnar 2. Glands 3. Smooth muscle 4. Cartilage plate CONDUCTING BRONCHIOLES 1. Epithelium a. Ciliated simple columnar 2. Smooth muscle RESPIRATORY BRONCHIOLES 1. Epithelium a. Cuboidal with ciliated & club cells ALVEOLI 1. Resident cells a. Pneumocytes b. Endothelial cells c. Fibroblast 2. Transient cells a. Dust & immune cells 3. Alveolar sac 4. Alveolar duct 5. Alveoli 6. Respiratory bronchioles 7. Terminal bronchioles PNEUMOCYTES 1. Epithelium a. 1: simple squamous b. 2: cuboidal 2. Type 1 & 2 pneumocytes 3. Capillaries 4. Air ALL 1. Alveoli 2. Bronchiole a. Pulmonary vessel 3. Bronchus a. Cartilage plate b. Pulmonary vessel DIGESTIVE SYSTEM GLANDS 1. Intrinsic glands 2. Extrinsic glands a. Major salivary glands GI TRACT 1. Lumen 2. GI tract wall a. Mucosa i. Epithelium ii. Lamina propria iii. Muscularis mucosae b. Submucosa c. Muscularis i. Longitudinal ii. Circular d. Serosa/adventitia MUCOSA 1. Mouth/pharynx/anal canal a. Non-keratinized stratified squamous eoithelium 2. Stomach/intestines a. Simple colulmnar 3. Lamina proprial 4. Muscularis mucosa 5. Goblet cells 6. Enteroendocrine cells SUBMUCOSA 1. Dense CT w/ blood and lymphatic vessels 2. Submucosal glands 3. Submucosal plexus MUSCULARIS 1. Inner circular 2. Outer longitudinal layer 3. Stomach: + oblique 4. Ends: skeletal muscle SEROSA 1. Loose CT 2. Serosa: abdominal cavity 3. Adventitia: mouth, pharynx, esophagus ALL 1. Mucosa a. Epithelium b. CT papillae c. Lamina propria d. Muscularis mucosae 2. Submucosa 3. Muscularis externa ORAL CAVITY & LIPS 1. Gingiva & hard palate a. Stratified squamous keratinized 2. Soft p;late, mouth floor, cheeks, lips a. Stratified squamous nonkeratinized 3. Lips a. Straited muscle b. Oral nonkeratinated – keratinized c. Skin d. Vermillion zone e. Oral mucosa f. Glands TONGUE 1. Filiform papillae 2. Epithelium 3. Adipose tissue 4. Lingual salivary glands 5. Skeletal muscle TEETH 1. Socket 2. Periodontal ligaments 3. Crown & root 4. Pulp cavity 5. Dentin 6. Enamel ESOPHAGUS 1. Mucosa a. Non-keratinized suqmous epithelium b. Muscualris mucosae 2. Submucosa 3. Muscularis a. Skeletal/skeletal & smooth/smooth 4. Adventitia 5. Ducts 6. Glands STOMACH 1. Mucosa a. Gastric pits 2. Cardia 3. Fundus 4. Pylorus 5. Gastric rugae 6. Gastric glands - Gastric juice a. Parietal cells b. Chief cells c. Mucous neck cells d. Enteroendocrine cells 7. Blood vessels 8. Submucosa 9. Muscularis externa a. + oblique 10. Serosa 11. Gastroesophageal junction 12. ECG SMALL INTESTINE 1. Circular folds, villi, microvilli 2. Intestinal glands a. Intestinal juice 3. Duodenal glands a. Alkaline mucus s 4. Intestinal malt 5. Ducts 6. Mucosa a. Muscularis mucosa LARGE INTESTINE 1. Epithelium a. Simple columnar 2. Mucosa a. Intestinal galnds i. Goblet cells 3. Submucosa 4. Muscularis externa 5. Taenia coli ANAL CANAL 1. Internal anal sphincter 2. External anal sphincter 3. Adipose tissue 4. Goblet cells 5. Intestinal gland 6. Lamina propria 7. Anus 8. Skin 9. 4cm a. Upper 3 i. Upper 15 ii. Lower 15mm b. lower 1 OTHER DIGESTIVE SYSTEM SALIVARY GLANDS 1. serous cells – pyramidal 2. mucous cells – cuboidal to columnar 3. major a. parotid b. submandibular c. sublingual 4. minor a. labial b. lingual c. buccal d. palatine 5. stroma a. CT capsule b. CT septa c. Reticular CT 6. Parenchyma a. Acini b. Duct system TYPES OF SALIVARY ACINI 1. Serous 2. Mucous 3. Mucoserous SALIVARY ACINI CELLS 1. Serous 2. Mucous 3. Myoepithelial DUCT SYSTEM FO SALIVARY GLAND 1. Intralobular a. Intercalated b. Striated 2. Interlobular 3. Main ducts SALIVARY GLAND 1. Serous acini 2. Striated & intercalated MAJOR SALIVARY ACINI 1. Parotid a. Myoepithelial cell b. CT septum c. Serous acini 2. Submandibular a. Striated duct b. Sermicuous acinus c. Serous demilunes 3. Sublingual a. Mucous acinus b. Basal nucleus c. Seromucous acinus GALLBLADDER 1. E: simple columnar 2. Cholecystokinin 3. NO SUMMUCOSA & MUSCULARIS EXTERNA 4. Mucosa a. E, LP (elastic fibers & BV), microvilli 5. Muscularis a. Smooth muscle fibers w/ CT *rich in elastic fibers) 6. Serosa a. Fundus, mesothelium (LCT) 7. Adventitia a. DCT LIVER 1. 2. 3. 4. 5. 6. 7. 8. 9. Parenchyma: hepatocytes Stroma a. Capsule of Glisson b. CT – type 3 collagen – reticulin, vessels c. Mesothelium Sinusoids Spaces of Disses Capsule CT septa Hepatic lobule a. Central vein b. Portal canal – portal triad Portal lobule a. Central vein Liver acinus a. Short axis b. Long axis c. Peripheral zone 1 d. Intermediate zone 2 e. Central zone 3 URINARY Kidney 1. Fibrous capsule 2. Perinephric fat 3. Renal fascia 4. Cortex 5. Medulla 6. Ernal pyramid 7. Minor calyx 8. Major calyx 9. Renal column 10. Renal pelvis 11. Ureter NEPHRON 1. Renal corpuscle a. Glomerulus b. Glomerular capsule/bowman’s capsule c. Macula densa d. Urinary space e. Glomerular capillaries f. 2 layers i. Parietal ii. Visceral 2. Tubular system a. Proximal convoluted tubule b. Nephron loop c. Distal d. Collecting ducts 3. Proximal CT a. Simple cuboidal b. Glomerulus c. Bowman’s capsule d. Bowman’s space 4. Distal CT a. Shorter 5. Thin limbs of loop of Henle a. Like capillaries 6. Collecting duct a. Domed-shape b. Clear lumen 7. ALL a. Proximal & distal CT b. Renal corpuscle c. Medullary ray d. e. f. g. Collecting ducts Arcuate artery Cortex Medulla UROTEHLIUM 1. Superficial 2. Intermediate regions 3. BM 4. LP – loos CT URETER 1. Lumen 2. Transitional epithelium 3. Dome cells 4. Mucosa a. Transitional epithelium b. LP 5. Muscularis a. Inner longitudinal b. Outer circular 6. Adventitia URINARY BLADDER 1. Mucosa a. Transitional epithelium/urothelium b. LP 2. Submucosa 3. Muscularis a. Detrusor muscles on walls b. Internal urethral orifice i. External US ii. Smooth c. External uerthral sphincter i. Skeletal d. Bundles of smooth muscles e. Dense irregular CT 4. Internal/middle/outer layers URETHRA 1. Male a. Prostatic b. Membranous c. Spongy 2. Female a. 4-5 cm b. Transitional c. Stratified squamous d. Pseudostratified columnar e. External straited muscle sphincter f. Lumen