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Test Bank For Abrams’ Clinical Drug Therapy Rationales for Nursing Practice 12th
Edition Geralyn Frandsen - ISBN/ISSN 9781975136130
Table of Content
SECTION 1 The Conceptual Framework of Pharmacology
Chapter 1 The Foundation of Pharmacology: Quality and Safety
Chapter 2 Basic Concepts and Processes
Chapter 3 Medication Administration and the Nursing Process of Drug Therapy
SECTION 2 Drug Therapy Throughout the Lifespan
Chapter 4 Pharmacology and the Care of Infants and Pediatric Patients Medication
Administration in Pediatrics
Chapter 5 Pharmacology and the Care of Adults and Geriatric
Patients Chapter 6 Pharmacology and the Care of Pregnant or
Lactating Woman Chapter 7 Pharmacology and Women’s Health
Chapter 8 Pharmacology and Men’s Health
SECTION 3 Drugs Affecting the Hematopoietic and Immune Systems
Chapter 9 Drug Therapy for Coagulation Disorders
Chapter 10 Drug Therapy for Dyslipidemia
Chapter 11 Drug Therapy for Hematopoietic
Disorders Chapter 12 Drug Therapy:
Immunizations
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Chapter 13 Drug Therapy to Decrease Immunity
Chapter 14 Drug Therapy for the Treatment of
Cancer
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SECTION 4 Drugs Affecting Inflammation and Infection
Chapter 15 Inflammation, Infection, and the Use of Antimicrobial
Agents Chapter 16 Drug Therapy to Decrease Pain, Fever, and
Inflammation Chapter 17 Drug Therapy With Corticosteroids
Chapter 18 Drug Therapy With Beta-Lactam Antibacterial Agents
Chapter 19 Drug Therapy With Aminoglycosides and
Fluoroquinolones
Chapter 20 Drug Therapy With Tetracyclines, Sulfonamides, and Urinary
Antiseptics Chapter 21 Drug Therapy With Macrolides and Miscellaneous Antiinfective Agents Chapter 22 Drug Therapy for Tuberculosis and Mycobacterium
avium Complex Disease Chapter 23 Drug Therapy for Viral Infections
Chapter 24 Drug Therapy for Fungal Infections
Chapter 25 Drug Therapy for Parasitic Infections
SECTION 5 Drugs Affecting the Cardiovascular System
Chapter
26
Drug
Therapy
for
Hypertension Chapter 27 Drug Therapy
for Dysrhythmias
Chapter 28 Drug Therapy for Coronary Heart
Disease Chapter 29 Drug Therapy for Shock and
Hypotension Chapter 30 Drug Therapy for Heart
Failure
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SECTION 6 Drugs Affecting the Respiratory System
Chapter 31 Drug Therapy for Nasal Congestion and Cough
Chapter 32 Drug Therapy to Decrease Histamine Effects and Allergic
Response Chapter 33 Drug Therapy for Asthma and Bronchoconstriction
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SECTION 7 Drugs Affecting the Renal and Digestive Systems
Chapter 34 Drug Therapy for Fluid Volume Excess
Chapter 35 Nutritional Support Products, Vitamins, and Mineral
Supplements Chapter 36 Drug Therapy for Weight Management
Chapter 37 Drug Therapy for Peptic Ulcer Disease and
Hyperacidity Chapter 38 Drug Therapy for Nausea and
Vomiting
Chapter 39 Drug Therapy for Constipation and Elimination
Problems Chapter 40 Drug Therapy for Diarrhea
SECTION 8 Drugs Affecting the Endocrine System
Chapter 41 Drug Therapy for Diabetes Mellitus
Chapter 42 Drug Therapy for Hyperthyroidism and Hypothyroidism
Chapter 43 Drug Therapy for Pituitary and Hypothalamic
Dysfunction Chapter 44 Drug Therapy to Regulate Calcium and
Bone Metabolism Chapter 45 Drug Therapy for Addison’s Disease
and Cushing’s Disease
Section 9 Drugs Affecting the Autonomic and Central Nervous System
Chapter 46 Physiology of the Autonomic and Central Nervous Systems and Indications for the
Use of Drug Therapy
Chapter 47 Drug Therapy for Myasthenia Gravis, Alzheimer’s Disease, and Urinary Retention
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Chapter 48 Drug Therapy for Parkinson’s Disease, Urinary Spasticity, and Disorders Requiring
Anticholinergic Drug Therapy
Chapter 49 Drug Therapy With Opioids
Chapter 50 Drug Therapy With Local Anesthetics
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Chapter 51 Drug Therapy With General Anesthetics
Chapter 52 Drug Therapy for Migraines and Other
Headaches Chapter 53 Drug Therapy for Seizure
Disorders and Spasticity Chapter 54 Drug Therapy for
Anxiety and Insomnia
Chapter 55 Drug Therapy for Depression and Mood
Stabilization Chapter 56 Drug Therapy for Psychotic Disorders
Chapter 57 Drug Therapy for Attention Deficit Hyperactivity Disorder and
Narcolepsy Chapter 58 Drug Therapy for Substance Abuse Disorders
Section 10 Drugs Affecting the Eye, Ear, and
Skin Chapter 59 Drug Therapy for Disorders of
the Eye Chapter 60 Drug Therapy for Disorders of
the Ear Chapter 61 Drug Therapy for Disorders of
the Skin
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Chapter 1, The Foundation of Pharmacology: Quality and Safety
G R A D E S B O O S T . C O M
1. A woman diagnosed with obsessive–compulsive disorder has been
prescribed oral paroxetine hydrochloride. What is the expected effect for
this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated
through the bloodstream to their sites of action in various body tissues, and
eventually eliminated from the body. Curative agents are given to cure a disease
process. In this case, paroxetine hydrochloride will control the symptoms but not
cure the disorder. Drugs with local effects, such as sunscreen and local anesthetics,
act mainly at the site of application. Paroxetine hydrochloride is not administered
parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or
intravenously.
PTS: 1
REF: p. 3, Introduction
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
mR
icAalDlyEm
haOt Mi s another name for
substance that has been cheG
SoBdOifOieSd.TW
.C
this type of medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring
substances that have been chemically modified. Synthetic drugs are more
standardized in their chemical characteristics, more consistent in their effects, and
less likely to produce allergic reactions. Biotechnology drugs involve manipulating
DNA and RNA and recombining genes into hybrid molecules that can be inserted
into living organisms. Prototype drugs are the first drug of a particular group to be
developed.
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PTS: 1
REF: p. 3, Drug Sources
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
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C. Anti-inflammatory
D. Antihypertensive
G R A D E S B O O S T . C O M
ANS: A
Rationale: Drugs are classified according to their effects on particular body systems,
their therapeutic uses, and their chemical characteristics. Morphine is classified as a
central nervous system depressant and will produce this effect in the client. A
central nervous system stimulant increases attention and raises mood. An antiinflammatory agent decreases inflammation at the site of tissue or joint
inflammation. An antihypertensive agent reduces blood pressure.
PTS: 1
REF: p. 3, Drug Classifications and
Prototypes OBJ:
1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember
NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs
to which drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic name
often indicates the drug group (e.g., drugs with generic
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names ending in “cillin” are penicillins). Selective serotonin reuptake inhibitors are
medications that have antidepressant effects; SSRI is a broad classification, not a
generic name. Diuretics are medications that increase urine output; diuretic is a
broad classification, not a generic name. ACE inhibitor is the broad classification for
the angiotensin receptor blockers, not the generic name.
PTS: 1
REF: p. 3, Drug Names
OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
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C. Occupational Safety and Health Administration
D. Food and Drug
Administration ANS: D
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G R A D E S B O O S T . C O M
Rationale: The Food and Drug Administration approves drugs for over-the-counter
availability, including the transfer of drugs from prescription to OTC status, and
may require clinical trials to determine the safety and effectiveness of OTC use. The
Public Health Service is regulated by the state to maintain the health of individual
citizens of the state. The Federal Trade Commission regulates imports and exports
throughout the nation. The Occupational Safety and Health Administration
regulates safety within the workplace.
PTS: 1
REF: p. 4, Prescription and Nonprescription
Drugs OBJ:
4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates
the manufacture and distribution of narcotics, stimulants, depressants,
hallucinogens, and anabolic steroids. The Food, Drug, and Cosmetic Act of 1938
revised and broadened FDA powers and responsibilities, giving the FDA control over
drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale,
and use of opium, cocaine, marijuana, and other drugs that the act d e f i Gn eRd Aa Ds
E
naSrcBoO
tiO
csS
. Th.eCSOhM
erley Amendment of 1912 prohibited fraudulent claims of drug
effectiveness.
PTS: 1
REF: p. 4, Prescription and Nonprescription
Drugs OBJ:
3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember
NOT: Multiple Choice
7. A nurse is responsible for maintaining an accurate count and record of the
controlled substances on the nursing division. This nursing action is regulated by
which U.S. law or agency?
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A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley
Amendment ANS: C
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G R A D E S B O O S T . C O M
Rationale: The Drug Enforcement Administration enforces the Controlled
Substances Act. Under this enforcement, nurses are responsible for storing
controlled substances in locked containers, administering them only to the people
for whom they are prescribed, recording each dose given, and maintaining an
accurate inventory. The Food, Drug, and Cosmetic Act of 1938 revised and
broadened FDA powers and responsibilities, giving the FDA control over drug
safety. The Public Health Service is regulated by the state to maintain the health of
individual citizens of the state. The Sherley Amendment of 1912 prohibited
fraudulent claims of drug effectiveness.
PTS: 1
REF: p. 7, Testing Procedure
OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
8. In Phase 1 clinical trials, the potential uses and effects of a new drug are
determined by which method?
A. Administering doses to healthy volunteers
B. Administering doses to people with the disease
C. Administering in placebo-controlled design
D. Calculating the risk-to-benefit ratio
ANS: A
Rationale: Phase 1 studies allow for the administration of the medication to healthy
volunteers to determine safe dosages, routes of administration, absorption,
metabolism, excretion, and toxicity. In Phase 2 studies, a few doses are given to a
ApDtoEmSB
certain number of subjects with the disease orGsR
ym
foOr O
wS
hiT
ch.tChO
eM
d r u g is
being studied and responses are compared with those of healthy subjects. Placebocontrolled designs are used in Phase 3 studies, in which half of the subjects receive
the new drug and half receive the placebo.
Calculating the risk-to-benefit ratio is used in Phase 2 studies to determine
whether the potential benefits of the drug outweigh the risks.
PTS: 1
REF: p. 7, Testing Procedure
OBJ: 5
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
9. A new medication for the treatment of Alzheimer’s disease is being administered to
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a group of subjects with the disease. The subjects receiving this medication are
unaware of whether they are being administered the medication or a placebo. This
testing occurs in which phase?
A. Phase 1
B. Phase 2
C. Phase 3
D. Phase
4 ANS: C
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G R A D E S B O O S T . C O M
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Rationale: In Phase 3, the drug is given to a larger and more representative group
of subjects. In double-blind, placebo-controlled designs, half of the subjects receive
the new drug and half receive a placebo (an inactive substance similar in
appearance to the actual drug), with neither subjects nor researchers knowing
which subjects receive which formulation. In Phase 1, a few doses are given to a
certain number of healthy volunteers to determine safe dosages, routes of
administration, absorption, metabolism, excretion, and toxicity. In Phase 2, a few
doses are given to a certain number of subjects with the disease or symptom for
which the drug is being studied and responses are compared with those of healthy
subjects. In Phase 4, the FDA evaluates the data from the first three phases for drug
safety and effectiveness, allows the drug to be marketed for general use, and
requires manufacturers to continue monitoring the drug’s effects.
PTS: 1
REF: p. 7, Testing Procedure
OBJ: 5
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
10. Which organization is responsible for approving new drugs in the United States?
A. The American Medical Association (AMA)
B. The American Pharmaceutical Association (APA)
C. The Food and Drug Administration (FDA)
D. The U.S. Pharmacopeia
ANS: C
Rationale: The Food and Drug Administration is responsible for approving new
drugs in the United States. The AmericaGn RMAeDdiEc S
a lBAOs O
soSciTat.i oCnOr M
epresents the
health care providers of the United States. The American Pharmaceutical Association
represents the pharmacists of the United States. The U.S. Pharmacopeia was
adopted in 1906 and is issued every 5 years under the supervision of a national
committee of pharmacists, scientists, and health care providers to provide
information concerning drug purity and strength.
PTS: 1
REF: p. 7, Testing Procedure
OBJ: 3
NAT: Client Needs: Safe and Effective Care Environment: Management of
Care TOP:
Chapter: 1: The Foundation of Pharmacology: Quality
and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember
NOT: Multiple Choice
11. A client with a long-standing dermatologic health problem has been advised to
use a drug with a local effect. The nurse should recognize what characteristic of
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this drug?
A. It affects only the organ system in which it is metabolized.
B. The drug requires application at multiple sites.
C. It is effective only as long as it is in contact with skin.
D. The drug acts primarily at the site where it is
applied. ANS: D
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G R A D E S B O O S T . C O M
Rationale: Drugs with local effects, such as sunscreen lotions and local
anesthetics, act mainly at the site of application. Those with systemic effects are
taken into the body, circulated through the bloodstream to their sites of action in
various body tissues, and eventually eliminated from the body. A drug with local
effect does not necessarily have to be applied at multiple sites, and its action may
affect tissues long after contact.
PTS: 1
REF: p. 3, Introduction
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Analyze
NOT: Multiple Choice
12. What is the primary importance of a black box warning?
A. It will result in the medication being removed from the market.
B. It acknowledges that the medication has been tested on only a selected
portion of the population.
C. It suggests that the prescription of the medication be avoided when
treating certain populations.
D. It alerts health care professionals of the potential of serious adverse
effects associated with the medication.
ANS: D
Rationale: Black box warnings identify the fact that a drug can cause serious adverse
effects. Subsequent withdrawal of approved and marketed drugs has occurred,
usually because of serious adverse effects that become evident only when the drugs
are used in a large, diverse population. The warning does not address testing or
target populations.
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PTS: 1
REF: p. 7, Testing Procedure
OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Analyze
NOT: Multiple Choice
13. A health care facility is complying with the mandates of U.S. The Drug
Enforcement Administration (DEA) concerning Schedule II medications when
implementing which nursing intervention? Select all that apply.
A. Access to narcotics is controlled by key or codes.
B. Narcotics are administered by prescriptions only.
C. Only selected narcotics may be automatically renewed.
D. The administration of individual narcotic doses is recorded in
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specific unit documentation.
E. Any recognized discrepancy involving a narcotic must be reported
to the appropriate facility authority.
ANS: A, B, D, E
Rationale: Nurses are responsible for storing controlled substances in locked
containers, administering them only to the people for whom they are prescribed,
recording each dose given on agency narcotic sheets and on the client’s medication
administration record, maintaining an accurate inventory, and reporting
discrepancies to the proper authorities. Prescriptions for Schedule II drugs cannot
be refilled; a new prescription is required.
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PTS: 1
REF: p. 7, Testing Procedure
OBJ: 5
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Analyze
NOT: Multiple Select
G R A D E S B O O S T . C O M
14. Which medication reference is considered to be an authoritative, well-respected
source of information? Select all that apply.
A. American Hospital Formulary Service
B. Drug Facts and Comparisons
C. Physicians’ Desk Reference
D. Lippincott’s Nursing Drug Guide
E. Package inserts provided with each medication
ANS: A, B
Rationale: An authoritative source is a work known to be reliable because its
authority or authenticity is widely recognized by experts in the field. Both the
American Hospital Formulary Service and the Drug Facts and Comparisons are
authoritative sources of drug information that have been recognized as reliable
sources of medication information. The Physicians’ Desk Reference is published
yearly and contains manufacturers’ published inserts for selected drugs. The
package inserts are produced by the drug manufacturers and do not necessarily
contain the details included in the correct options. Lippincott’s Nursing Drug Guide
is an example of a drug handbook, not a compilation of manufacturers’ inserts and
intended as a student resource.
PTS: 1
REF:GRpA
. 1D1E, SoBuOrcOeS
s oTf.DCruOgMInformation OBJ: 7
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Select
15. A nursing student in a pharmacology class should be encouraged to study the
medications according to which categorization? Select all that apply.
A. Prototype
B. Controlled substance
C. Drug use
D. Generic names
E. Therapeutic classification
ANS: A, E
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Rationale: The nursing student should concentrate on therapeutic classifications
and their prototypes. Controlled substances limit the medications studied to one
broad classification. Drug use is only one part of the broad classification. Generic
names are only one aspect of the medication.
PTS: 1
REF: p. 12, Strategies for Studying
Pharmacology OBJ: 6
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
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KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Select
G R A D E S B O O S T . C O M
16. A client diagnosed with an autoimmune disorder has just been prescribed a
synthetic drug. Which characteristic is a noted advantage of synthetic drugs?
A. The client is at a lesser risk for an allergic reaction.
B. The client will require less frequent dosing.
C. The medication will be available on an over-the-counter basis.
D. The medication is available in a wider variety of administration routes.
ANS: A
Rationale: Synthetic drugs are more standardized in their chemical characteristics,
more consistent in their effects, and less likely to produce allergic reactions. They
do not necessarily require less frequent dosing and may or may not be available
OTC. They are not noted to be available in a wider variety of administration routes
than naturally occurring substances.
PTS: 1
REF: p. 3, Drug Sources
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
17. A client is confused and has stated to the nurse, “I wasn’t sure whether I’m
supposed to take Tylenol or acetaminophen.” To best address the client’s concern,
the nurse should base the response on what information concerning generic and
trade names?
CeOsMin their
A. Prescribers should referGsR
olAelDyEtoSgBeO
neOrS
icTn.am
recommendations and written prescriptions.
B. A generic name is independent of any particular drug manufacturer.
C. Generic names change frequently, but trade names are more consistent.
D. Prescribers should refer solely to trade names in their
recommendations and written prescriptions.
ANS: B
Rationale: A generic name is related to the chemical or official name and is
independent of the manufacturer. Drugs may be prescribed and dispensed by
generic or trade name. Generic names do not change, while trade names vary
according to time and place.
PTS: 1
REF: p. 3, Drug Names
OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Analyze
NOT: Multiple Choice
18. What is the primary purpose of American drug laws?
A. To ensure maximum choice for consumers
B. To expedite the workload of health care providers
C. To protect the safety of the public
D. To enhance the efficient delivery of health care
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G R A D E S B O O S T . C O M
ANS: C
Rationale: The main goal of drug laws is to protect the public by ensuring that
drugs marketed for therapeutic purposes are safe and effective. Efficiency and
choice are valid considerations, but neither is the primary goal of American drug
legislation. Workload is expedited when delivery of health care is efficient.
PTS: 1
REF: p. 4, Prescription and Nonprescription
Drugs OBJ:
3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
19. A nurse who provides care on a postsurgical unit frequently administers Schedule II
drugs to clients. Which aspect of administering these drugs falls under the auspices
of the U.S. Drug Enforcement Administration?
A. Performing a thorough client assessment prior to administration
B. Recording each dose administration on an agency narcotic sheet
C. Informing clients of the potential risks and benefits of such drugs prior to
the first dose
D. Assessing the client shortly after administration to ensure existence of the
expected therapeutic effect
ANS: B
Rationale: Nurses are responsible for storing controlled substances in locked
containers, administering them only to people for whom they are prescribed,
recording each dose given on agency narcotic sheets
aG
ndRoAnDtE
heScBliO
enOt’SsTm.eC
diO
caMtion administration record, maintaining an accurate
inventory, and reporting discrepancies to the proper authorities. The other given
actions are appropriate nursing activities, but they are not within the scope of the
DEA authority.
PTS: 1
REF: p. 7, Testing Procedure
OBJ: 5
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Analyze
NOT: Multiple Choice
20. Trials of a new drug are scheduled to begin soon. The testing methodology will
integrate the stipulations of the National Institutes of Health (NIH) Revitalization
Act. According to this act, the manufacturer must address which requirement?
A. Independently fund the entire testing process.
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B. Make the results of the testing process publicly available.
C. Include women and minorities in the testing process.
D. Exclude any potential for financial gain during the testing
process. ANS: C
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Rationale: In 1993, the United States Congress passed the National Institutes of
Health (NIH) Revitalization Act, which formalized a policy of the NIH that women
and minorities be included in human subject research studies funded by the NIH
and that women and minorities be included in clinical drug trials. This act does not
specifically address the financial structure of testing or the accessibility of
information.
PTS: 1
REF: p. 7, Testing Procedure
OBJ: 5
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember
NOT: Multiple Choice
21. A hospital nurse is vigilant in ensuring the safe use of medications and consistently
applies the rights of medication administration. What are the rights of medication
administration? Select all that apply.
A. Right to refuse prescribed medication
B. Right route for effective medication therapy
C. Right to effective medication education
D. Right evaluation of expected results
E. Right to low-cost medication therapy
ANS: A, B, C, D
Rationale: The traditional rights of medication administration (right drug, right
dose, right client, right route, right time, right reason, and right documentation)
now include additional rights that should also be considered (right education, right
evaluation, and right to refuse the medication). While important, there is not a
recognized right to low-cost medication.
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PTS: 1
REF: p. 8, Rights of Medication Administration
OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember
NOT: Multiple Select
22. A client’s current medication administration record includes a drug that the nurse
recognizes as an Institute for Safe Medication Practices (ISMP) high-alert
medication. This designation signals the nurse to what characteristic of the drug?
A. It can only be administered by a health care provider or advanced practice nurse.
B. Administration must be cosigned by a second registered
nurse or practical/vocational nurse.
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C. It is currently undergoing Phase 4 testing and is pending full FDA approval.
D. Administration errors carry a heightened risk of causing significant client harm.
ANS: D
Rationale: The Institute for Safe Medication Practices (ISMP) identifies drugs that
when used in error have a heightened risk of causing significant client harm. Such
drugs are not limited to health care provider or advanced practice nurse
administration. The drug would have completed the testing and approval
procedure, and administration does not necessarily require a cosignature.
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PTS: 1
REF: p. 9, High-Alert Medications
OBJ: 5
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand
NOT: Multiple Choice
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Ch. 2
1. Which cellular structure stores hormones and other substances and
packages these substances into secretory granules?
A)
Golgi apparatus
B)
Endoplasmic reticulum
C)
Mitochondria
D)
Lysosome
Ans:
A
Feedback:
The golgi apparatus stores hormones and other substances. The endoplasmic
reticulum contains ribosomes, which synthesize proteins, including enzymes
that synthesize glycogen, triglycerides, and steroids and those that metabolize
drugs and other chemicals. The mitochondria generate energy for cellular
activities and require oxygen. Lysosomes are membrane-enclosed vesicles that
contain enzymes capable of digesting nutrients (proteins, carbohydrates, fats),
damaged cellular structures, foreign substances (bacteria), and the cell itself.
2. A patient is suffering from a cough associated with an upper respiratory
infection. Which oral medication will likely produce the most therapeutic
effect?
A)
A tablet
B)
An expectorant
C)
A topical spray
D)
A timed-release tablet
Ans:
B
Feedback:
Liquid medications are absorbed faster than tablets or capsules. Expectorants
are liquid medications. A tablet is an oral medication that has a slower onset of
action than a liquid medication. A topical spray can be sprayed to the back of
the throat and provides only a local effect. A timed-release tablet is an oral
medication that has a slower onset and longer duration of action.
3. A patient is administered an oral contraceptive. Which of the following is the
process that occurs between the time the drug enters the body and the time
that it enters the bloodstream?
A)
Absorption
B)
Distribution
C)
Metabolism
D)
Excretion
Ans:
A
Feedback: