Forensic science CODIS SUBMITTED BY :- RANJEET SINGH COURSE :- M.Sc. Forensic science CONTENT 1 What is CODIS 2 History of CODIS 3 Functioning of CODIS 4 Future of CODIS 5 CODIS use in forensic Science DNA (Deoxyribonucleic acid) DNA is a self-replicating genetic material, that occurs in every living organism. It is a carrier of all genetic information. It carries instructions for organisms to grow, survive, develop and reproduce. What is CODIS CODIS [Combined DNA index system] DNA Database[ created & maintained by FBI] CODIS is a tool used by law enforcement agencies to aid in solving crimes. CODIS doesn’t solve crime. It just link information. It’s a very quick system compared to traditional DNA analysis. HISTORY OF CODIS “ In 1995, the United Kingdom established the world’s first National DNA database, NDNAD in England. In 1998 the United state introduced national combined DNA index system. All 50 States participate CODIS Hierarchy CODIS consist of 3 levels of information. FUNCTION OF CODIS CODIS’s primary function is to facilitate connection between DNA evidence collected from different crime scenes, suspects, and victims. It can link cases, and even help identify missing & unidentified persons. CODIS helps to identify potential suspects. Link know offenders to current investigation. CODIS SEARCH CODIS Site These 13 sites [Loci] that the FBI uses are called CODIS sites. CSF1PO FGA 85% THO1 TPOX WHAT MAKES US VWA DIFFERENT? D3S1358 D5S818 D7S820 D8S1179 D13S317 D16S539 D18S51 D21S11 FUTURE OF CODIS The CODIS system will continue to expand in the future. However, while the FBI has begun combining other forms of biometric data—iris scans, facial features, fingerprints, and palm prints, for example—it’s unlikely to combine any of those with CODIS. Complete The CODIS database is designed to be as unbiased as possible ; extraneous identifying information could hamper that. CODIS USE IN FORENSIC SCIENCE REFERENCE 1. Federal Bureau of Investigation. "CODIS-NDIS Statistics." (accessed August 1, 2008) 2. Jobling, M., et al. Encoded evidence: DNA in forensic analysis. Nature Reviews Genetics 5, 739–751 (2004) doi:10.1038/nrg1455 (link to article) 3. Oak Ridge National Laboratory. "DNA Forensics." (accessed August 1, 2008) 4. National Conference of State Legislatures. "DNA Databanks." (accessed August 1, 2008) 5. Reilly, P. Legal and public policy issues in DNA forensics. Nature Reviews Genetics 2, 313–317 (2001) doi:10.1038/35066091 (link to article) 6. Weir, B. The rarity of DNA profiles. Annals of Applied Statistics 1, 358–370 (2007) doi:10.1214/07-AOAS128 T H A N K YO U !