INDUSTRIAL ENZYMES: FOOD AND FEED MARKET Science Market Regulation UBIC CONSULTING 2012 Marketing development Strategy consulting Partnership searches Information systems TECHNICAL AND ECONOMICAL PROSPECTS FOOD AND FEED 350 pages This comprehensive report is based on in-depth interviews with food companies completed by a desk review. It provides for DECISION MAKERS a global understanding of the sector as well as an outlook on its future. MARKET ANALYSIS FOOD SEGMENTS Trends and outlook Use of ingredients: volume-value Manufacturers profiles Users opinions Regulation Food industry Functional food Food supplements Sports food Industrial markets Clinical nutrition INGREDIENTS COUNTRIES COVERED Industrial enzymes North America Western Europe Asia Australia- New Zealand INDUSTRIAL ENZYMES: FOOD AND FEED MARKET OBJECTIVES M A R K E T Food consumption trends and expectations Consumer market trends by food segments Prospective MANUFATURERS Food industry orientations Applications in food segments Consumption RESEARCH New researches and new developments INTRODUCTION Enzymes are technological auxiliaries, meaning "substances which are not consumed as dietary ingredients in themselves and voluntarily used in the transformation of primary matter, of foodstuffs or their ingredients. They respond to a certain technological objective during the treatment or transformation and can have, as a result, the unintentional presence of technically inevitable residues of this substance or its derivatives in the final product providing that these residues pose no health risk and have no technological effects on the final product". However, four enzymes figure on the present provisory list regulated by the EU: it concerns papaïne, lysozyime (E 1105), glucose oxydase (E 1102) and invertase (E 1103). In fact, it seems that these enzymes present a residual activity in the final product (they maintain a role in the final product). To this end, because of the status of certain ones, several aspects of capital importance are added for the development for the use of enzymes in the coming years: it concerns the diversity of their applications, new methods linked to their production (genetic engineering, engineering of proteins), the public infatuation with natural products (made naturally or containing natural elements) and their specificity which allows us to envisage possible new uses (in chemistry, for example). These aspects will be envisaged successively. Three aspects will be the object of particularly attention because they are the ones most directly concerned with an evolution in the use of enzymes: it concerns the dairy industry, the flourmilling/bread-making and beverage industries. The use of enzymes as technological aids represents a decisive stake in years coming as much technical point of view as strategical and economical: In the food sector: •Enzymes can modify and improve functional, tasting and nutritional properties of substrates, ingredients or products : e.g. "shaping" of oils and fats, elimination of bitter peptides, texturation of proteins, improving the fibres' digestibility; •Enzymes can play a role in products'preserving as antioxydants or antibiotics: e.g. lysozyme, lactoperoxydase, catalase and phenoloxydases; •Enzymes can facilitate physical process of extraction or separation (cereals'cracking, extraction of sugars); •Enzymes are used in analytical tools (dosage of sugars, lactates, amino acids, fermentation following). In fine chemicals and pharmaceuticals: •We are looking for their specificity regard to chemical catalysts (racemate resolution, bioconversion of aromatic compounds, non-conventional synthesis) that permits to have a better yield; •They allow to avoid the long and expensive stages of depollution; •The molecules produced get the "natural". But the use of enzymatic catalysis in industry remains delicate because it is situated at the interface of several specialities such as biochemistry, microbiology, chemical genius and enzymatic genius. Besides, since several years new process conditions have been planned out that yield to a new soaring of enzymatic genius. These conditions are: INDUSTRIAL ENZYMES: FOOD AND FEED MARKET OBJECTIVES M A R K E T Food consumption trends and expectations Consumer market trends by food segments Prospective MANUFATURERS Food industry orientations •Use at high temperature (e.g. thermostable proteases) or low temperature (amylases for new starch process, fishes' enzymes); •Use at extreme pH or searching optimal pH according to the others stages of a process; •Use in organic solvent, reversion of hydrolysis reactions by increasing substrate concentration, decreasing water activity or removing final product; •Use in gaseous phase, under high pressure, in salted middle; •The improvement of immobilization technics, of retention and regeneration of cofactors. So these new conditions of use, the techniques of genetic engineering and progress in fermentation technology will allow novel uses of known enzymes or the use of new enzymes. These enzymes will be commercialized by the large firms such as NOVO, Miles Laboratories when large demand is expected whereas small and medium firms will sell specific processes and enzymes for special applications. Meanwhile, own supply is current in chemical and pharmaceutics and captive production risks also to develop in the food sector (e.g. C.P.C., A.D.M., Clinton in U.S., Roquette, Rhône-Poulenc, Unilever in Europe). That would render again more complex the exchanges between producers and users and more delicate the working up in industries of the various possibilities that offers enzymatic genius. Thus, this study should determine on: the demand for enzymes, the criteria for choice, the market characteristics and the consumption prospects; the new applications for existing enzymes, applications for new enzymes and possible use and constraints. STRUCTURE OF THE PROGRAM Applications in food segments V o l. I FO O D and FEE D Consumption RESEARCH New researches and new developments V o l. II STA RCH D E R IV A T IV E S SW EETENER S A M IN O A C ID S ENZYM E M ARKET V o l. IV DETERGENTS PA PER E N V IR O N M E N T V o l. III PHA RMACY F IN E C H E M IC A L S AROMA S INDUSTRIAL ENZYMES: FOOD AND FEED MARKET OBJECTIVES M A R K E T WORLD INDUSTRIAL ENZYME MARKET (ANALYTICAL ENZYME EXCLUDED) 2000-2010 Food consumption trends and expectations Consumer market trends by food segments Prospective MANUFATURERS TYPE OF ENZYME 2000 2010 Microbial enzymes 1,500 2,500 Bacterial proteases Amylglucosidases Glucose isomerases Bacterial amylases Pectinases Food industry orientations Applications in food segments Fongic enzymes coagulating Fongic amylases Fongic proteases Diverses APPLICATION Washing products Glucose Glucose Glucose, Textile 30.7 50 Fruit juices, wines 27.8 41 Cheese SAMPLE43 3.4 TABLE 5 Bakery 28.6 Bakery Consumption Extraction enzymes 124.6 188 RESEARCH Animal rennet 104 150 Cheese Papaïne 6.8 12 Brewery Pancreatine 7.3 15 Leather Pharmacy Papaïne 6.5 11 Pharmacy New researches and new developments INDUSTRIAL ENZYMES: FOOD AND FEED MARKET TABLE OF CONTENTS INTRODUCTION 5 DEVELOPMENTSPROGRAM OF THE STUDY 7 THE MARKET - SUMMARY 9 FUTURE 16 1. ENZYMES: NATURE - CLASSIFICATION- SOURCES 15 1.1 NATURE 15 1.2. CLASSIFICATION 15 1.3. SOURCES OF ENZYMES 16 1.4. REGULATION 16 2. PRODUCTION OF ENZYMES BY MICROBIOLOGIC MEANS 21 2.1. PRODUCTION ON AN INDUSTRIAL SCALE : EXAMPLE OF THE CELLULASE DETRICHODERMA LONGIBRACHIATUM (T.REESEI) 21 2.2. GENERALIZATION-CONSTRAINTS LINKED TO THE PRODUCTION OF ENZYMES BY MICROBIOLOGIC MEANS 24 3- INNOVATION IMPACT 27 3.1- IMMOBILIZED ENZYMES 27 3.2-PROTEIN AND ENGINEERING OF ENZYMES 28 4. APPLICATION IN THE DAIRY INDUSTRY 34 4.1. GENERAL FRAMEWORK - ENZYME USED 34 4.1.1. APPLICATION FIELDS 34 36 4.1.2-TECHNOLOGICAL AND ECONOMIC ASPECTS 4.2. THE MARKET 44 4.2.1. VOLUME, CONSUMPTION TRENDS 44 4.2.2. USER’S EXPECTATIONS 48 4.2.3- USER’S PROFILES 50 ALLGAULAND (GERM) 50 KASEREI CHAMPIGNON (GERM) 52 BORDEN (USA) 54 GLANBIA (IR) 55 LACTALIS (F) 56 CAMPINA (NL) 58 KRAFT (GERM) 60 SEOUL DAIRY PRODUCTS CO., LTD. (SOUTH KOREA) NAMYANG DAIRY PRODUCTS CO., LTD. (SOUTH KOREA) SNOW BRAND MILK PRODUCTS (JAPAN) 5. BEVERAGE INDUSTRY 5.1-TECHNOLOGY 5.1.1- APPLICATION FIELDS 5.1.2- BREWING 5.1.3- WINE PRODUCTION AND FRUIT AND VEGETABLE PREPARATION 5.2. THE MARKET 5.2.1. VOLUME AND CONSUMPTION TRENDS 5.2.2. USER’S EXPECTATION 5.2.3-USER’S PROFILES MILLER BREWING CO. (USA) CANANDAIGUA WINE CO. (USA) SUTTER HOME (USA) CAVE DE RIBEAUVILLE (F) CAVE DEFAIX (F) LACTALIS (F) JFA PAMPRYL (F) AMERICAN FRUIT PROCESSOR (USA) BULMER (UK) DOLE (PHILIPINES) 6. FLOUR MILLING /BREAD MAKING 6.1.TECHNOLOGY 6.1.1- FIELDS OF APPLICATION 6.1.2- ENZYMES USED 6.1.3-IMPLEMENTATION 6.1.4- MAIN AREAS OF PRESENT RESEARCH 6.2 THE MARKET 6.2.1. VOLUME AND TREND CONSUMPTION 6.2.2. USER EXPECTATIONS 6.2.3. USERS PROFILES PAINS JACQUETS (F) 61 64 66 68 68 68 69 77 85 85 97 98 98 101 103 104 105 106 107 109 111 112 114 114 114 115 120 121 123 123 128 129 129 INDUSTRIAL ENZYMES: FOOD AND FEED MARKET CAMPBELL TAGGART (USA) FLOWERS INDUSTRIES (USA) INTERSTATE BRANDS (USA) DR. A. OETKER NAHRUNGSMITTEL KG (GERM.) CARGILL (F) BRAUN (GERM) LIMAGRAINS (F) 7. ENZYMATIC TREATMENT OF PROTEINS 7.1. AREAS OF APPLICATION 7.1.1 - MEAT AND SEAFOOD INDUSTRY 7.1.2-HYDROLYSATS OF VEGETAL PROTEINS 7.2. MARKET 7.2.1. VOLUMES AND CONSUMPTION TRENDS 7.2.2- USER’S EXPECTATION 7.2.3. USER’S PROFILES AMERICAN MEAT PROTEIN CORP. (USA) SOCOPA (F) 8- ENZYMATIC LIPID TREATMENT 8.1- APPLICATION FIELDS 8.1.1- MANUFACTURE OF OILS AND MARGARINES 8.1.2- PRODUCTION OF FATTY ACIDS AND PUR β-MONOGLYCERIDES 8.1.3- ESTERIFICATION PRODUCTS 8.1.4- PRODUCTION OF LYSO-LECITHIN 8.2- MARKET 8.2.1. VOLUME AND CONSUMPTION TRENDS 8.2.2. USER’S EXPECTATIONS 8.2.3. USER’S PROFILE LESIEUR (F) SOYAMAINZ (GERM) HÜLS (GERM) LUCAS MEYER (CARGILL, GERM) 131 133 135 137 138 139 141 142 142 142 136 132 132 132 133 133 135 136 136 136 139 139 140 140 140 170 171 171 172 173 174 9- ANIMAL NUTRITION 175 9.1- TECHNOLOGY 175 9.2- MARKET 177 9.2.1-VOLUME AND CONSUMPTION TRENDS 177 180 9.2.2 USER’S EXPECTATIONS 9.2.3- USER’S PROFILE 181 SOYAMAINZ (GERM) 181 FAVOR PARKER (UK) 182 CENTRAL SOYA (F) 183 RALTSON PURINA (EUROPE) 184 10. NEW USER’S SEGMENTS 185 10.1. IMPROVEMENT OF PROTEIN TEXTURING PROPERTIES 185 10.1.1. OPTIMIZATION OF PROTEOLYSIS 185 185 10.1.2. USE OF TRANSGLUTAMINASES 10.2.ENZYMATIC TREATMENT OF TEXTURING AGENTS: EXAMPLE OF ALGINATES 186 INDUSTRIAL ENZYMES: FOOD AND FEED MARKET ORDER FORM Complete Study Study purchase includes one year update available on-line on UBIC’s Extranet All sections € 2,400 COMPANY ________________________________________________________________________ Name _________________________________ Position _________________________________ _______________________________________________________________________________ Assistance is also available for specific questions _________________________________________________________________________________ ______________________________________ Date _____________________________________ Signature__________________________________ www.ubic-consulting.com UBIC CONSULTING IN THE WORLD Partners Russia UBIC IRELAND UBIC EUROPE UBIC USA UBIC CHINA UBIC JAPAN UBIC FRANCE UBIC MENA India Mexico Argentina UBIC BRAZIL UBIC USA 5020 Campus Drives NEWPORT BEACH CA-92660 Phone: 1 949 296 7544 Fax: 1 949 752 2287 info@ubicusa.com UBIC EUROPE TechnoArk 1 3960 SIERRE Switzerland Phone: +41 (0) 27 456 1440 +41 (0) 27 456 1444 Fax: +41 (0) 27 456 1447 info@ubiceurope.com UBIC INDONESIA UBIC IRELAND 45 Glencarraig DUBLIN 13 Ireland Phone: 353 1 832 47 12 Fax: 353 1 832 12 77 ubic@ubic-consulting.com UBIC JAPAN 5 -4-3-1015 Motomachi, Chuo-ku Kobe, 650-0022 JAPAN Phone: +81 50 3693 4318 Fax: +81 50 3488 4318 japan@ubic-consulting.com