Cambridge IGCSE™ * 0 0 1 4 4 7 4 2 7 5 * BIOLOGY 0610/41 Paper 4 Theory (Extended) May/June 2024 1 hour 15 minutes You must answer on the question paper. No additional materials are needed. INSTRUCTIONS ● Answer all questions. ● Use a black or dark blue pen. You may use an HB pencil for any diagrams or graphs. ● Write your name, centre number and candidate number in the boxes at the top of the page. ● Write your answer to each question in the space provided. ● Do not use an erasable pen or correction fluid. ● Do not write on any bar codes. ● You may use a calculator. ● You should show all your working and use appropriate units. INFORMATION ● The total mark for this paper is 80. ● The number of marks for each question or part question is shown in brackets [ ]. This document has 20 pages. Any blank pages are indicated. DC (PB/SG) 330335/3 © UCLES 2024 [Turn over 2 1 (a) Fig. 1.1 is a photograph of a fish. Fig. 1.2 is a photograph of an amphibian. Fig. 1.1 Fig. 1.2 State two visible features that distinguish the fish in Fig. 1.1 from the amphibian in Fig. 1.2. 1 ................................................................................................................................................ 2 ................................................................................................................................................ [2] (b) Fish, amphibians and mammals are all vertebrate groups. State the name of one other vertebrate group. ............................................................................................................................................. [1] © UCLES 2024 0610/41/M/J/24 3 (c) Fig. 1.3 shows the circulatory system of a fish. Fig. 1.4 shows the circulatory system of an amphibian. gill capillaries heart lung and skin capillaries heart ventricle atrium body capillaries body capillaries Fig. 1.3 Fig. 1.4 Describe the similarities and the differences between the circulatory systems of the fish and the amphibian in Fig. 1.3 and Fig. 1.4. They both dont have septum that separates the left side from the right ................................................................................................................................................... They both oxygenate the blood ................................................................................................................................................... ................................................................................................................................................... Amphibians has 4 heart chambers ................................................................................................................................................... Amphibians have double circulation, fish has1 ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ............................................................................................................................................. [4] © UCLES 2024 0610/41/M/J/24 [Turn over 4 (d) Explain the advantages of the type of circulatory system in mammals compared with the type of circulatory system in fish. double circulation prevents deoxygenated blood from mixing with oxygenated ................................................................................................................................................... blood ................................................................................................................................................... prevents backflow of blood ................................................................................................................................................... ................................................................................................................................................... blood flows through the heart twice ................................................................................................................................................... ................................................................................................................................................... ............................................................................................................................................. [3] (e) Explain how the structure of arteries and veins relates to the difference in the pressure of the blood transported by these vessels. arteries, like aorta, have thick muscles to push blood away from the heart ................................................................................................................................................... ................................................................................................................................................... veins, like vena cava, have thin muscles as they bring blood with low pressure to ................................................................................................................................................... the heart so vessels wont burst ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ............................................................................................................................................. [4] © UCLES 2024 0610/41/M/J/24 5 (f) Table 1.1 shows the names of some organs and the name of the main artery that brings blood to the organ. Complete Table 1.1. Table 1.1 name of the organ name of the artery that brings blood to the organ lung renal artery liver [3] [Total: 17] © UCLES 2024 0610/41/M/J/24 [Turn over 6 2 (a) Fig. 2.1 shows the internal body temperature of a human and the external environmental temperature during six hours in one day. 40 38 36 34 temperature / °C 32 30 28 26 0 1 2 3 4 time / hours key: internal body temperature external environmental temperature Fig. 2.1 © UCLES 2024 0610/41/M/J/24 5 6 7 7 (i) The internal body temperature range is from 36.4 °C to 37.0 °C. State the range of the external environmental temperature shown in Fig. 2.1. ..................................................................................................................................... [1] (ii) Explain the results for the internal body temperature shown in Fig. 2.1. As temperature increases, internal body temperature stays constant for 1 ........................................................................................................................................... hours before increasing slightly ........................................................................................................................................... ........................................................................................................................................... Temperature continues increasing reaching its maximum at 39*C and body ........................................................................................................................................... internal temperature fluctuates but remains normal ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [6] © UCLES 2024 0610/41/M/J/24 [Turn over 8 (b) Fig. 2.2 shows a cross‑section through human skin. A F E B D C Fig. 2.2 Table 2.1 shows the names of some parts of the skin, the letter identifying the part in Fig. 2.2 and its role in maintaining internal body temperature. Complete Table 2.1. Table 2.1 name of the part letter in Fig. 2.2 role in maintaining internal body temperature insulation E detect temperature changes [3] [Total: 10] © UCLES 2024 0610/41/M/J/24 9 3 (a) Fig. 3.1 shows a drawing of a root hair cell and Fig. 3.2 shows a drawing of a palisade cell. chloroplast mitochondrion mitochondria Fig. 3.1 Fig. 3.2 Explain the reasons for the difference in the numbers of mitochondria and chloroplasts between the root hair cell and the palisade cell, shown in Fig. 3.1 and Fig. 3.2. root hair cells have more mitochondria for more energy in respiration mitochondria ............................................................................................................................. active transport ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... root is the source so ore chloroplasts are needed for photosynthesis chloroplasts .............................................................................................................................. to produce sugars for the plant ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... [5] © UCLES 2024 0610/41/M/J/24 [Turn over 10 (b) Fig. 3.3 is a photomicrograph of a cross‑section of part of a xerophyte leaf. B A Fig. 3.3 (i) Explain why the part labelled A in Fig. 3.3 is a tissue. because its a group of cells working together to perform a specific function ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [2] (ii) Describe two ways the structure labelled B in Fig. 3.3 is adapted for its function. reduce water loss from plant 1 ........................................................................................................................................ ........................................................................................................................................... gaseous exchange 2 ........................................................................................................................................ ........................................................................................................................................... [2] © UCLES 2024 0610/41/M/J/24 11 (iii) Describe one way the leaves of xerophytes are adapted to their environment. trap moist air to reduce transpiration rolled leaves ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [1] (iv) Describe one way the roots of xerophytes are adapted to their environment. deep roots reach for underground water ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [1] [Total: 11] © UCLES 2024 0610/41/M/J/24 [Turn over 12 4 (a) A student investigated the effect of lactase on three different liquids: • • • milk lactose‑free milk sucrose solution. The student used an indicator to test for the presence of glucose. A sample of each liquid was tested before and after treatment with lactase. The indicator turned brown in the presence of glucose. The indicator remained blue in the absence of glucose. Table 4.1 shows the results of the tests. Table 4.1 liquid colour before treatment with lactase colour after treatment with lactase milk blue brown lactose‑free milk brown brown sucrose solution blue blue (i) Explain the results for the three liquids shown in Table 4.1. lactase breaks down milk to give fatty acid and glucose so it is brown after ........................................................................................................................................... treatment ........................................................................................................................................... lactose-free milk already has glucose to it is brown before and after ........................................................................................................................................... treatment ........................................................................................................................................... sucrose solution has no glucose so it remains blue before and after ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [3] © UCLES 2024 0610/41/M/J/24 13 (ii) The student kept the solutions at a temperature that was close to the optimum during the investigation. Using your knowledge of the effect of temperature on enzyme activity, explain why this was important. enzyme activity increases as temperature increases ........................................................................................................................................... ........................................................................................................................................... the lactase speeds up the rate of reaction as it works best at optimum ........................................................................................................................................... temperature ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [4] (b) As part of a balanced diet, some governments recommend that children drink milk that has vitamin D added to it. (i) Suggest the dietary reasons for this advice. to strengthen the bones and prevent vitamin D defiance such as rickets ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [2] (ii) Describe what is meant by a balanced diet. a diet that consists of carbohydrates, proteins, fats, and vitamin C to ........................................................................................................................................... maintain a healthy lifestyle and metabolism ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [2] [Total: 11] © UCLES 2024 0610/41/M/J/24 [Turn over 14 5 Fig. 5.1 is a graph showing the effect of temperature on the rate of transpiration from the upper and lower surfaces of a leaf that is provided with a constant supply of water. X Y lower surface upper surface rate of transpiration temperature Fig. 5.1 (a) Describe the results shown in Fig. 5.1. As temperature increases, the rate of transpiration increases more at the lower ................................................................................................................................................... surface than upper surface ................................................................................................................................................... ................................................................................................................................................... rate of transpiration becomes constant as wind has become the limiting factors ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ............................................................................................................................................. [3] © UCLES 2024 0610/41/M/J/24 15 (b) Explain reasons for the shape of the graph for the upper surface of the leaf at X and at Y in Fig. 5.1. at X ........................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... at Y ........................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... [4] (c) Suggest how the structure of the lower surface differs from the upper surface of the leaf used in this investigation. ................................................................................................................................................... ................................................................................................................................................... ............................................................................................................................................. [1] [Total: 8] © UCLES 2024 0610/41/M/J/24 [Turn over 16 6 (a) Polio is a viral disease that can cause nerve damage in humans. In one area, polio vaccination began in 1957. Fig. 6.1 shows the number of cases of polio in this area between 1950 and 1970. 600 500 number of cases of polio 400 300 200 100 0 1950 1952 1954 1956 1958 1960 1962 1964 1966 1968 1970 year Fig. 6.1 (i) Calculate the percentage change in the number of cases of polio between 1950 and 1952 in Fig. 6.1. Give your answer to two significant figures. Space for working. .............................................................% [3] © UCLES 2024 0610/41/M/J/24 17 (ii) Explain how vaccination causes the results shown between 1958 and 1970 in Fig. 6.1. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [5] (iii) Explain why the polio vaccine does not protect you from other diseases. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ..................................................................................................................................... [2] (b) Blood clotting helps to prevent some infections. Outline how a blood clot is formed and how it can prevent infections. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ............................................................................................................................................. [3] (c) State the name of the component of blood responsible for transporting blood cells. ............................................................................................................................................. [1] [Total: 14] © UCLES 2024 0610/41/M/J/24 [Turn over 18 7 Fig. 7.1 is a flowchart showing the stages of eutrophication. (a) Complete Fig. 7.1. fertilisers enter a lake decomposition increases the concentration of the growth of ......................................... increases .......................................... on the surface of the lake increases underwater producers die because they are unable to blocking ......................................... bacterial decomposers use oxygen for ......................................... ......................................... .............................. from entering the water in the lake resulting in the death of organisms requiring ............................ oxygen Fig. 7.1 [6] (b) A scientist obtained a sample of the bacterial decomposers and grew them in a flask. The resources available for bacterial growth in the flask became limiting. The size of the bacterial population was estimated during the investigation and these data were plotted on a graph. (i) State the name of the expected shape of the population growth curve that would be drawn on the graph. ..................................................................................................................................... [1] (ii) State the name of the initial phase of bacterial growth. ..................................................................................................................................... [1] (iii) State one factor, other than a lack of resources, that would cause bacteria to die during the death phase. ..................................................................................................................................... [1] [Total: 9] © UCLES 2024 0610/41/M/J/24 19 BLANK PAGE © UCLES 2024 0610/41/M/J/24 20 BLANK PAGE Permission to reproduce items where third‑party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. To avoid the issue of disclosure of answer‑related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge Assessment International Education Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cambridgeinternational.org after the live examination series. Cambridge Assessment International Education is part of Cambridge Assessment. Cambridge Assessment is the brand name of the University of Cambridge Local Examinations Syndicate (UCLES), which is a department of the University of Cambridge. © UCLES 2024 0610/41/M/J/24