Cancer type Biomarker Lung cancers ROS-1 EGFR ALK KRAS Bowel cancer BRAF KRAS EGFR Breast Oestrogen receptors (ER) Progesterone receptors (PR) Human Epidermal Receptor 2 (HER2) Ovarian and Breast BRCA1 BRCA2 Leukaemia, lymphoma JAK2 BCR-ABL B2M CD19 CD20 BCL-2 Prostate Prostatic Acid Phosphatase (PAP) Prostate Specific Antigen (PSA) Various solid tumours Programmed cell death protein 1 (PD-1) Programmed cell death ligand 1 (PD-L1) BRAF V600 mutation HER2/neu