Grade 12 Life Sciences: Genetic Modification Genetic modification This involves creating DNA sequences through biotechnological process that would not occur naturally This biotechnology can be applied to plants, animals and bacteria. This enables traits to be introduced that are not naturally present in a species, e.g. plants with an insecticide gene to repel insects. One biotechnological process used in genetic modification is RECOMBINANT TECHNOLOGY. This involves finding a gene that codes for the required protein, isolating it and moving it into the cells of another organism which makes the protein for which the new gene codes. e.g. The manufacture of biosynthetic insulin The advantages: Large quantities rapidly created Relatively inexpensive Has few side effects Page 1 of 2 Grade 12 Life Sciences: Genetic Modification Recombinant DNA http://explorecuriocity.org/desktopmodules/cc_videoplayer/wfrm/wfrmprintdocument.aspx?contentid=2800 Video: https://www.youtube.com/watch?v=FAMRQz7fOaE – Recombinant DNA Process (Music is Funky so watch without the music!!!) Research: Not for marks! Choose one of the following and explain how they produce the serums with recombinant engineering: 1. Recombinant human growth hormone (HGH, somatotropin) 2. Recombinant blood clotting factor VIII… 3. Recombinant hepatitis B vaccine… 4. Three common tests for diagnosing HIV infection Page 2 of 2
