Representative photographs of collodion membrane and harlequin ichthyosis. Case 1, collodion baby , day 1 (emollient has been applied). Case 1, collodion baby, day 5 (emollient has been washed off). Case 2, collodion baby, day 1 Case 2, collodion baby, day 3 Case 2, collodion baby, day 7 Case 3, Harlequin ichthyosis, day 1 Case 3, Harlequin Ichthyosis, day 1. Photograph originally published in: Kelsell DP, Norgett EE, Unsworth H et al. Mutations in ABCA12 underlie harlequin ichthyosis, the most severe congenital skin disorder. Am J Hum Genet 2005 May;76(5):794-803. Reproduced for BPSU with parental consent. Case 3, Harlequin ichthyosis, day 10 Case 3, Harlequin ichthyosis, day 10