Republic of the Philippines Department of Health OFFICE OF THE SECRETARY __ February 6, 2024 DEPARTMENT MEMORANDUM No. 2024 - (073 TO: ALL UNDERSECRETARIES AND ASSISTANT SECRETARIES; DIRECTORS OF BUREAUS AND CENTERS FOR HEALTH ___(CHDs);_ DEVELOPMENT MINISTER OF HEALTH_IN BANGSAMORO AUTONOMOUS REGION MUSLIM CHIEF: MINDANAO DICAL AND SANITARIA CENTERS, HOSPITALS, INSTITUTES; DOH ATTACHED AGENCIES AND INSTITUTIONS AND ALL OTHERS CONCERNED ;_ gov.ph SUBJECT: uidelines on D-19 through the PD. + Strate On July 21, 2023, through Proclamation No. 297, the President declared the lifting of the Public Health Emergency throughout the Philippines due to COVID-19. is This Department Memorandum (DM) hereby issued to provide an update to the existing protocols, aligning them with the latest policy shifts and to provide guidance to relevant stakeholders and the general public. I. all PREVENT A. Wearing of Masks 1. indoor and outdoor settings shall be voluntary, however, in the in following settings: Wearing of face masks it is highly encouraged a. b. B. Healthcare facilities, including, but not limited to, clinics, hospitals, laboratories, nursing homes, and dialysis clinics, and; Medical transport vehicles, such as ambulances and paramedic rescue vehicles. Hygiene and disinfection 1. at Practice frequent and proper handwashing using soap and clean water for least 20 seconds. Use an alcohol-based hand sanitizer if soap and water are not available. Observe the following respiratory etiquette mainly when sneezing and coughing, especially when in public and crowded places: a. Cover mouth and nose with tissues or wipes. b. Properly dispose of used tissues or wipes immediately after. Trunk Line 8651-7800 local 1113, 1108 Building 1, San Lazaro Compound, Rizal Avenue, Sta. Cruz, 1003 Manila Direct Line: 711-9502; 711-9503 Fax: 743-1829 @ URL: http://www.doh.gov.ph; e-mail: dohosec(@doh. c. If tissue is not available, use one’s upper sleeve or arm. d. Avoid coughing into hands which can easily spread viruses. e. Wash hands with soap and water after coughing or sneezing, after contact with an infected person, and after touching potentially contaminated surfaces. Refrain from touching one’s eyes, nose, and mouth, especially with unwashed hands, and after touching potentially contaminated instruments and surfaces. Ensure regular disinfection, particularly of frequently touched surfaces and objects that may be contaminated with the virus. C. Ventilation 1, for air quality in all facilities are met as stipulated Ensure ventilation requirements in Department of Labor and Employment (DOLE) Department Order (DO) 224-21 “Guidelines on Ventilation for Workplaces and Public Transport to Prevent and Control the Spread of COVID-19” dated March 03, 2021, which can be accessed through this link: https://bit.ly/DOLEGuidelineson Ventilation. Il. DETECT A. Public health surveillance: Surveillance objectives and processes for COVID-19 shall follow the objectives and processes for pan-respiratory illness surveillance as described in Department Memorandum No. 2022-0526 (Interim Guidelines on the Pilot Implementation of Integrated Sentinel Surveillance for SARS-CoV-2, Severe Acute Respiratory IlInesses, and Influenza-like Illnesses). 1. Cases shall continue to be classified and reported following the prescribed surveillance case definitions of COVID-19 based on Department Memorandum No. 2022-0501 (Interim Revised Case Definitions for COVID-19). The Epidemiology Bureau shall release updated guidelines for pan-respiratory virus surveillance once available. RT-PCR testing shall continue to be the gold standard used for confirmatory testing for surveillance purposes. Severe and critical COVID-19 cases and cases connected to large clusters or unusual events shall be prioritized for surveillance testing, ideally using multiplex influenza/SARS-CoV-2 tests offered by referral laboratories in line with Department Memorandum No. 2022-0106 (Advisory on the use of Multiplex Testing Kits and Updated Testing Algorithm in the Detection of Respiratory Viruses in the ILI and SARI Surveillance). Health care workers are not required to undergo regular COVID-19 testing, unless otherwise determined by their Infection Prevention and Control Committees. 4. Centers for Health Development shall continue to: a. Check their case and health care metrics regularly to determine which areas are at increasing risk for respiratory illness spread and impact. A list of such areas shall be regularly provided to the Epidemiology Bureau; and b. Ensure submission compliance and monitoring of Disease Reporting Units (DRUs) and other health facilities, including those that perform facility-based rapid antigen testing. 5. Identified areas with increased risk shall implementthe following activities: a. Active case finding and contact tracing, especially for cases confirmed to be positive for Variants of Concern or of Interest and sublineages under close monitoring; b. Increased RT-PCR testing in the region, especially targeting suspect cases and identified symptomatic close contacts; and c. Sending of samples for whole genome sequencing (WGS) to meet the quota in line with Department Memorandum No. 2021-0182 (Interim Guidelines for the Biosurveillance of SARS CoV-2 and Management of Cases of Variants of Concern). B. Testing for clinical management 1. Individuals who are at-risk of progression to severe disease, especially senior citizens, individuals with comorbidities, and the immunocompromised, are recommended to undergo confirmatory testing prior to the start of any COVID-19 treatment regimen. are For individuals with mild symptoms and those who not at-risk of progression shall isolate immediately, to severe disease, testing shall be optional. They preferably at home if requirements for home isolation are met (see Annex A), and monitor for progression of signs and symptoms guided by health care workers onsite or through teleconsult for appropriate management. are not at-risk of progression to Testing of the asymptomatic close contacts who vaccination shall be disease status of regardless optional. If testing will be severe COVID-19 done, use of RT-PCR shall remain the gold standard for testing. RT-PCR shall remain the gold standard for COVID-19 testing. Rapid antigen tests shall be used for immediate management of symptomatic cases and when RT-PCR is not readily available. If rapid antigen test is negative, RT-PCR shall be used for confirmatory testing. Self-administered antigen testing shall be recommended only for symptomatic individuals within 7 days from onset of symptoms, especially if capacity for timely RT-PCR results is limited or not available. Self-administered antigen test kits shall not be recommended for (1) asymptomatic close contacts and (2) screening of asymptomatic individuals. For other cases not stated above, self-administered antigen testing shall be optional, including for community level actions wherein case management of probable and confirmed cases remain the same. If the self-administered antigen test is positive, the patient shall seek appropriate consultation with a physician for further assessment and management, and facilitate proper coordination for disease reporting. For further guidance, please refer to DOH DM 2022-0033 “Guidelines on the Use of Self-Administered Antigen Testing for COVID-19” which can be accessed through this link: https://bit.ly/DM20220033 UseofSelfRATforCOVID19. Testing for screening asymptomatic individuals, particularly patient watchers and patients for consultation or prior to admission in hospital and other medical facilities is not recommended. However, with regard to the implementation of the national guidelines and protocols for COVID-19, all hospitals and health facilities are given the authority to establish and maintain their own Infection Prevention and Control Committee (IPCC). Ill. QUARANTINE and ISOLATE The following are the quarantine and isolation protocols that must be observed regardless of vaccination status in order to prevent and reduce the risk of transmission of COVID-19. However, the following individuals should wear a well-fitted face mask for at least 10 days. Please refer to Annex B for the summary. close A. Quarantine 1, who were exposed to confirmed COVID-19 positive individuals, shall not be required to undergo quarantine. contacts B. Isolate Asymptomatic 1. Individuals with acute respiratory symptoms OR confirmed COVID-19 cases who are _asymptomatic or with mild symptoms, are recommended to undergo home isolation for 5 days OR until afebrile/ fever-free for at least 24 hours without using antipyretics (e.g. Paracetamol) and with improvement of respiratory earlier. Isolation may be shortened upon the advice of the symptoms, whichever healthcare provider. is Confirmed COVID-19 positive cases _with moderate to severe symptoms, OR individuals, isolate for at least 10 immunocompromised_ are recommended days from the onset of signs and symptoms following advice of the attending physician, including whether to be admitted in a health care facility. For severe disease and immunocompromised, isolation can be discontinued only upon the advice of your healthcare provider. to C. Requirements for home isolation can be found in Annex A. IV. TREAT A. Clinical management guidelines are based on the updated recommendations by the Recommendations. While there are existing Philippine COVID-19 Living international guidelines and living systematic reviews on COVID-19, there is a need to localize the recommendations from the evidence in our setting by local experts, end-users, and other pertinent stakeholders. An updated list of drugs for the treatment and management of COVID-19 can be found in the following annexes: 1. Annex C - Drugs in the Management Adult Patients with COVID-19 Pediatric Patients with COVID-19 2. Annex D - Drugs in the Management of of Recommended drugs or medicines with no valid Certificate of Product Registration (CPR) issued by the Philippine Food and Drug Administration (FDA) may be accessed through other regulatory pathways (i.e., Emergency Use Authorization or Compassionate Special Permit) subject to evaluation and/or conditions set by the FDA. For further details on the aforesaid pathways, please refer to Administrative Order No. 2020-0028 entitled “Amendment to Administrative Order No. 4 s. 1992 entitled “Policy Requirements for Availing Compassionate Special Permit (CSP) for Restricted Use of Unregistered Drug and Device Product/ Preparation” or other issuances promulgated by the FDA, necessary. as B. Individuals experiencing COVID-like symptoms are highly encouraged to consult with the nearest primary care provider or call the DOH National Patient Navigation and Referral Center (NPNRC) through 1555 and select option (2) for immediate and well as corresponding management and interventions. proper assessment as Vv. REINTEGRATE A. Neither repeat testing (showing a negative COVID-19 test) nor requiring medical certificates are required for resumption of work or entrance to school. mental health and psychosocial support especially to individuals in quarantine and isolation. They may also download the DOH Lusog-Isip Mobile Application for free (available in both Apple store or Google play store) or access the National Center for Mental Health (NCMH) Crisis Hotline or the DOH Regional Helplines for mental health and psychosocial support concerns. B. Promote VI. VACCINATION Despite the lifting of the COVID-19 Public Health Emergency in the country, COVID-19 vaccination is recommended all eligible populations pursuant to Administrative Order (AO) No. 2022-0005 entitled Omnibus Guidelines on the Implementation of the National Deployment and Vaccination Plan for COVID-19 vaccines. The prioritization framework (Annex E) shall be followed in allocation decisions for the roll-out of the vaccines. to A. The expansion of eligibility for additional doses or booster vaccination of other COVID-19 vaccine products shall be based on future amendments to the authorizations of the FDA. Current stocks of COVID-19 vaccines shall be used for primary series, additional dose, and booster dose vaccination for all eligible populations based on prevailing guidelines. B. The COVID-19 vaccine acquired through donations shall be allocated to the priority groups Al to A3. C. No Wrong Door Policy in All Vaccination Sites: For vaccine recipients who seek to complete the necessary COVID-19 primary series and booster doses, as eligible to their priority group, shall be provided, scheduled, or advised to have their recommended COVID-19 vaccination. If the requesting party is not eligible for a COVID-19 vaccine, they shall be offered other primary care services, based on stage. For further details, the Omnibus Health Guidelines per Life Stage may be accessed https://bit.ly/OmnibusHealthGuidelines. life at VIL. Risk Communication and Community Engagement (RCCE) A. Localize and disseminate the preventive measures discussed in Section I, including changes in evidence and protocols, to make preventive behaviors easier to do and reduce risk of transmission of disease. the Promote healthy behaviors including the practice of the seven healthy habits (Health is Life campaign) and promotion of primary care and disease prevention (KonsulTayo campaign) through the communication packages disseminated by the Health Promotion Bureau (HPB) and Centers for Health Development Health Promotion Units. Ensure integration of planning, implementation, and recalibration of demand and communication interventions with immunization generation program interventions. Utilize evidence-based planning through the microplanning process co-developed with WHO and UNICEF. Modules for Risk Communication, and Microplanning through Community Engagement, may be accessed https://bit.ly/CHDMicroplanProcess. D. Expand partnerships with civil society organizations, non-government organizations, academe, and other development evaluation of RCCE interventions. VIII. partners for co-creation, implementation, and Integration of COVID-19 Vaccination into the Immunization Programs and Other Relevant Health Services The National Immunization Program (NIP) and the Emerging and Re-emerging Infectious Disease (EREID) team shall work towards the technical and operational integration of COVID-19 vaccination into immunization programs, primary health care, and other relevant health services to improve coverage and efficiency of immunization programs by cost sharing and maximizing opportunities for vaccination of target populations. A. Vaccinators Utilize the workforce trained for COVID-19 vaccination to support other vaccination programs through the NIP, to strengthen immunization services, optimize resources, and enhance vaccination coverage for both COVID-19 and routine vaccines. Cold Chain capacity Integrate with the storage and logistics of other programs which require cold chain facility. Utilize this to store and distribute vaccines such as under the NIP, various medications and biological products that require temperature-controlled storage. Regular inventory and reporting of all vaccines, medicines, and commodities with particular focus on near expiry and stock out of supplies shall be conducted. Service Delivery Incorporate planning for COVID-19 Vaccination Program along with other immunization programs and service delivery plans (e.g. local investment plan for health, annual operational plan, annual investment plan, work and financial plan). Offer and recommend other routine health services corresponding to the vaccine recipient’s life stage (e.g. reproductive health, nutrition, immunization, deworming, health screening services for various diseases disorders, linkage or coordination for further management, if necessary), provided that provision of medicines, drugs, or vaccines do not have a contraindication to co-administration, or that the additional service provided does not unduly delay the vaccination processes. or site IX. REPEALING CLAUSE Issuances inconsistent with or contrary to this DM are hereby repealed, amended, or modified accordingly. All other provisions of existing issuances which are not affected by this DM shall remain valid and in effect. For guidance and dissemination. GLORIA J. BALBQA, MD, MPH, MHA, CEO VI, CESO Officer-In-Charge ffice of the Secretary III Annex A. Requirements for Home Isolation A. Infrastructure 1. Well-ventilated room 2. Line for communication with family and health workers 3. Utilities such as electricity, potable water, cooking source, etc. 4. Solid waste and sewage disposal Accommodation Ability to provide a separate bedroom for the patient, or separate bed with enough distance (>3 feet or 1 meter) so long as there are no vulnerable persons (e.g. immunocompromised, elderly) in the household 2. Accessible bathroom in the residence; if multiple bathrooms are available, one bathroom designated for use by the patient 1. Resource for Patient Care and Support Primary caregiver who will remain in the residence and who is 1) fully vaccinated, 2) not at high risk for complications, and 3) is educated on proper 1. precautions N wH Medications for pre-existing conditions as needed; family planning supplies as desired Digital thermometer, preferably one patient, disinfected before and after use Meal preparation MAME per Masks, tissues, and other hygiene products Laundry Household cleaning products Personal Protective Equipment For the patient: surgical mask per day for each day of isolation 2. For at least one caregiver, but preferably for the whole household: surgical mask per day for each day of isolation 3. For disinfection: gown, head covering, gloves for disinfection 1. Home Monitoring Kit 1. Vital signs recording mechanism 2. 3. Thermometer Pulse oximeter 4. BP apparatus, if with history of hypertension 5. Recommended meal plan or information materials on proper nutrition and access to basic necessities, including delivery services 6. Psychosocial support materials or proposed activities during isolation 7. Family health plan and instructions to caregivers, to include proper wearing, removal, and disposal of PPE, instructions on disinfection, avoidance of household members being unmasked when eating or drinking, and sharing of personal items for eating and hygiene. 8. Medicines to manage common symptoms of COVID-19 all Annex B. Updated masking, quarantine and isolation protocols* Masking / Quarantine Asymptomatic close contact exposed to confirmed COVID-19 positive individual Asymptomatic but confirmed COVID-19 positive case Confirmed COVID-19 positive case with mild symptoms OR individuals with acute respiratory symptoms Isolation Protocols e@ No need to quarantine; and e@ Wear a well-fitted face mask for at least 10 days. e Home isolation for 5 days OR until afebrile/ e@ fever-free for at least 24 hours without using antipyretics (e.g., Paracetamol) and with improvement of respiratory symptoms, whichever is earlier; and Wear a well-fitted face mask for at least 10 days. Note: Isolation may be shortened upon your healthcare provider. Confirmed COVID-19 positive case with moderate to severe symptoms, OR immunocompromised / the advice of Isolation for at least 10 days from onset of signs and symptoms following advice of the attending physician, including whether to be admitted in a health care facility; and Wear a well-fitted face mask for at least 10 days. Note: For severe disease and immunocompromised, discontinue isolation only upon the advice of your healthcare provider. *regardless of vaccination status Annex C. Treatment Patients* For Mild-Moderate Recommended Indication (based on COVID LCPG) Medicine Non-hospitalized patients with at Remdesivir COVID-19 in Non-Hospitalized Adult Evidence Review least 1 risk factor** for progression to severe disease Non-oxygen requiring patients with Link to COVID LCPG Molnupiravir at least one risk factor*** for progression (within 5 days of symptom onset) Unvaccinated, symptomatic adult patients with high risk**** for progression to severe disease (within 5 days of symptom onset) Nirmatrelvir + Symptomatic, non-hospitalized patients with risk factor***** for severe COVID-19 (only when the not predominant circulating variant Omicron SARS-CoV-2) Casirivimab + Imdevimab Unvaccinated non-hospitalized patients with mild to moderate COVID-19 infection with at least 1 risk factor****** for progression to severe disease Tixagevimab Ritonavir (Paxlovid) is +Cilgavimab Certainty of Evidence and Strength of Recommendation Moderate certainty mi https: org/remdesivir-evid of evidence; Strong ence-summary-3/ recommendation https://www.psmid, org/molnupiravir-e vidence-summary- 2/ Very low certainty of evidence; Weak recommendation https:/Avww.psmid. org/paxlovid-evide nee-summary/ Moderate certainty of evidence; Strong recommendation https://www.psmid. org/casitivimab-im devimab-evidence- summary-4/ Very low certainty of evidence; Weak recommendation https://www.psmid. org/tixagevimab-cil gavimab-evidence- Very low certainty of evidence; Weak recommendation summary-2/ *Should be used with the supervision of a physician **Risk factors for progression: age >60 years, hypertension, cardiovascular or cerebrovascular disease, diabetes mellitus, obesity, immunocompromised, chronic mild or moderate kidney disease, chronic liver disease, chronic lung disease, current cancer, or sickle cell disease ***Risk factors for progression: age >60 years, active cancer, chronic kidney disease, chronic obstructive pulmonary disease, obesity, serious heart conditions or diabetes mellitus ****Risk factors: >60 years of age, BMI >25 kg/m2; cigarette smoking, immunocompromised; chronic lung, cardiovascular, kidney or sickle cell disease, hypertension, diabetes, cancer, neurodevelopmental disorders or other medically complex conditions, or medical-related technological dependence ****4Risk factors: age >50 years, obesity, cardiovascular disease (including hypertension), chronic lung disease (including asthma), chronic metabolic disease (including diabetes), chronic kidney disease (including receipt of dialysis), chronic liver disease, and immunocompromised conditions factors: age >65 years, body-mass index 235 kg/m2, cardiovascular disease (including hypertension), chronic lung disease (including asthma), chronic metabolic disease (including diabetes), chronic kidney disease (including receipt of dialysis), chronic liver disease, and immunocompromised conditions *KHKKARISK 10 Treatment For Moderate-Severe COVID-19 in Hospitalized Adult Patients* Recommended Indication (based on COVID LCPG) Medicine Patients with COVID-19 infection requiring oxygen supplementation but do not require mechanical ventilation invasive (For patients who progress mechanical ventilation while on remdesivir, the drug can be continued) Remdesivir + Dexamethasone Hospitalized critical COVID-19 patients on high-flow nasal cannula oxygenation, noninvasive ventilation, or invasive mechanical ventilation Baricitinib + Corticosteroids Patients showing rapid respiratory deterioration and/or requiring high doses of oxygen (high-flow nasal cannula, noninvasive or invasive mechanical ventilation) and with elevated biomarkers of inflammation (CRP) Tocilizumab + systemic steroids Hospitalized patients with moderate, severe or critical COVID-19 disease unless there are any contraindications Standard dose prophylactic anticoagulation Patients with severe and critical COVID-19 (up to 10 days of use) **Standard dose at 6mg to 12mg/day among adults with severe and critical COVID-19 Dexamethasone Patients with severe and critical COVID-19 (up to 5- 10 days of use) Methylpredniso lone 1-2mg/kg/day Link to COVID to Certainty of Review Evidence Evidence and Strength of Recommendation https://www.psmi d.org/remdesivir-e vidence-summary- Low certainty of evidence; Weak recommendation LCPG 3/ https://www.psmi d.org/baricitinib-e vidence-summary- Moderate certainty of evidence; Strong recommendation 2/ https://www.psmi d.org/tocilizumabevidence-summar Moderate certainty of evidence; Strong recommendation y/ d.org/anticoagulati Low certainty of evidence; Weak recommendation https:/Awww.psmi d.org/corticosteroi ds-evidence-summ of evidence; Strong https://www.psmi on-evidence-sum mary-3/ Moderate certainty recommendation ary-2/ https://www.psmi d.org/corticosteroi ds-evidence-summ ary-2/ Very low certainty of evidence; Weak recommendation *Should be used with the supervision of a physician 11 Annex D. Drugs in the Management of Pediatric Patients with COVID-19 Treatment For Mild COVID-19 in Children* Recommended Indication (based on COVID LCPG) Medicine Link to COVID LCPG Evidence Review Certainty of Evidence and Strength of Recommendation Hospitalized or ambulatory children with mild to moderate COVID-19 infection with at least one (1) risk factor for disease progression Remdesivir https://www.ps mid.org/remdes ivir-evidence-su mmary-3/ Very low certainty of evidence; Weak recommendation Unvaccinated, symptomatic pediatric patients 12 years and older weighing least 40 kg with risk for high progression to severe disease Nirmatrelvir+ https://www.ps Ritonavir (Paxlovid) mid.org/paxlovi d-evidence-sum Low certainty of evidence; Weak recommendation at mary/ *Should be used with the supervision of a physician Treatment For Hospitalized Moderate to Severe COVID-19 in Children* Recommended Indication Medicine Link to COVID LCPG Evidence Review Certainty of Evidence and Strength of Recommendation Remdesivir + Dexamethasone https:/Awww.ps Very low certainty of evidence; Weak recommendation (based on COVID LCPG) Children with COVID-19 infection requiring oxygen supplementation but do not require mechanical ventilation mid.org/remdes ivir-evidence-s ummary-3/ *Should be used with the supervision of a physician 12 Annex E, Prioritization framework Categories of Priority Populations for COVID-19 Vaccination Description Priority Group Eligible Population Group A Priority Group Al Frontline workers in health facilities both national and local, private and public, health professionals and non-professionals like students in health and allied professions courses with clinical responsibilities, nursing aides, janitors, barangay health workers, etc. Sub-priority Al.1 Al.2 COVID-19 referral hospitals designated by the DOH; Public and private hospitals and infirmaries providing COVID-19 care, as prioritized based on service capability, starting from level 3 hospitals, to level 2 hospitals to level 1 hospitals, and then infirmaries; Among hospitals with a common service capability, the order of priority shall be from facilities owned by the DOH, then facilities owned by LGUs, and then facilities owned by private entities; Al13 Isolation and quarantine facilities such as temporary treatment and monitoring facilities and converted facilities (e.g. hotels, schools, etc) that cater to COVID-19 suspect, probable, and confirmed cases, close contacts, and travellers in quarantine; Al.4 Remaining hospitals including facilities of uniformed services not catering to COVID-19 cases; A15 Government owned primary care based facilities such as Urban Health Centers, Rural Health Units and Barangay Health Stations, birthing homes, and Local Health Offices to include members of BHERTS, contact tracers, social workers; vaccinators Al.6 Stand-alone facilities, clinics and diagnostic centers, and other facilities and health care workers otherwise not specified (e.g. clinics, dialysis centers, dental clinics, and COVID-19 laboratories), dealing with COVID-19 cases, contacts, and specimens for research purposes, screening and case management coordinated through their respective local government units; and Al1.7 Closed institutions and settings such as, but not limited to, nursing homes, orphanages, jails, detention centers, correctional facilities, drug treatment and rehabilitation centers, and Bureau of Corrections. Al1.8 Outbound Overseas Filipino Workers (OFW)s for deployment within the next four months (Expanded Al) A1.9 (Expanded A1) Immediate family members of health care workers which refers to all members 18 years old and and above, of the household where the health care worker lives to include house mates, helpers, and drivers 13 Priority Group A2 | Senior citizens aged 60 years old and above Sub-Priority A2.1 A2.2 [Priority Group A3 in Institutionalized senior citizens including those registered nursing homes and other group homes with elderly working together (e.g. convents). All other senior citizens, including bed-ridden senior citizens at home. A2 plus one household member shall be in constant close contact with, and/or living in the same household with Senior Citizens. Adults with comorbidities not otherwise included in the preceding categories. Priority shall be given to adult whose comorbidities are among the top causes of COVID-19 and national morbidity and mortality for prioritization to include chronic respiratory disease, hypertension, cardiovascular disease, chronic kidney disease, cerebrovascular disease, malignancy, diabetes, obesity, chronic liver disease, neurologic disease, and immunodeficiency state. A sub-group under the Priority Group A3 which needs to secure medical clearance prior to vaccination shall include the following: os mone Pediatric A3 Autoimmune disease HIV/Malignancy Cancer Transplant patients Undergoing steroid treatment Patients with poor prognosis/Bed-ridden patients Comorbidities for the Pediatric A3 needing to secure medical clearance prior to vaccination shall include the following: a. Medical complexity: long term dependence on technical support e.g. tracheostomy associated with developmental delay and/or genetic anomalies b. Genetic conditions: Down’s Syndrome (Trisomy 21), Glucose-6-phosphate dehydrogenase deficiency (G6PD), genetic disorders affecting the immune systems such as primary immunodeficiency disorders, thalassemia, and other chromosomal abnormalities c. Neurologic conditions: Seizure Disorder, Autism Spectrum Disorders (ASDs), Cerebral Palsy, Stroke in the Young, Chronic Meningitis e.g. Tuberculosis, chronic neuromuscular diseases, and chronic demyelinating diseases d. Metabolic/ endocrine diseases: Diabetes Mellitus (DM), Hypothyroidism, Diabetes Insipidus (DI), Adrenal insufficiency, Hypopituitarism, and other hereditary metabolic diseases. e. Cardiovascular diseases: Hypertension, Congenital Heart Diseases (CHDs), Cardiomyopathy, Rheumatic Heart Disease (RHD), Mitral Valve Disease, Pulmonary Hypertension with Right Heart Failure. f. Obesity: BMI > 95th percentile for age and height g. HIV Infection h. Tuberculosis: Pulmonary (collapse/ consolidations, with empyema, 14 Expanded A3 Priority Group A4 and miliary), Extrapulmonary, (pleural effusion, pericarditis, abdominal, genitourinary, central nervous system, spinal column, bone, joint, cutaneous, ocular and breast), and Disseminated (involvement of two (2) or more organs). i. Chronic Respiratory Diseases: Chronic Lung Diseases (Bronchiectasis, Bronchopulmonary Dysplasia, Chronic Aspiration Pneumonia), Congenital respiratory malformation, Restrictive Lung Diseases, neuromuscular disorders, syndromic with hypotonia, skeletal disorders, chronic upper and lower airway obstruction Obstructive Sleep Apnea, Tracheomalacia, Stenosis, (Severe Bronchial Asthma). j. Renal Disorders: Chronic Kidney Diseases, Nephrotic Syndrome, End-Stage Renal Disease (ESRD), patients on dialysis and continuous ambulatory peritoneal dialysis (CAPD), Glomerulonephritis (e.g. lupus nephritis), Hydronephrosis. Diseases: Chronic Liver Disease, k. Hepatobiliary Cirrhosis, Malabsorption Syndrome. 1. Immunocompromised state due to disease or treatment: Bone marrow or stem cell transplant patients, solid organ transplant anemia, (leukemia, hematological malignancies recipients, thalassemia), cancer patients on chemotherapy, severe aplastic anemia, autoimmune or autoinflammatory disorders requiring immunosuppressive therapy (e.g. Systemic Lupus long-term Rheumatoid Arthritis), patients receiving Erythematosus, immune-modulating biological therapy [e.g. Anti - Tumor Necrosis Factor (TNF), rituximab, among others], patients receiving long-term systemic steroids [> one (1) month], functional asplenia, patients who underwent splenectomy. Pregnant and lactating women Private sector workers required to be physically present at their designated workplace outside of their residences; employees in government agencies and instrumentalities, including government-owned and controlled corporations and local government units; and informal sector workers and self-employed individuals who may be required to work outside their residences, and those working in private households. A4.1 Private sector workers who work outside their homes A4.2 Employees in government agencies and instrumentalities, including government-owned or controlled corporations (GOCCs) and local government units A4.3 Informal sector workers and self-employed who work outside their homes and those working in private households Priority Group A5 Poor population based on the National Household Targeting System for Poverty Reduction (NHTS-PR) or other verification mechanisms of the local government not otherwise included in the preceding categories Rest of the Adult Population (ROAP) Rest of the Pediatric Population (ROPP) 15 References . . . . . . . . . Department of Health Administrative Order No. 2022-0051 “Revised National Policy on Infection Prevention and Control in All Public and Private Health Facilities” Department of Health Administrative Order No. 2022-0005 “Omnibus Guidelines on the Implementation of the National Deployment and Vaccination Plan for COVID-19 vaccines” Department of Health Department Circular No. 2023-0324 “Updated Health Protocols following Lifting of the COVID-19 Public Health Emergency” Department of Health Department Memorandum No. 2022-0433 “Updated Guidelines on the Minimum Public Health Standards for the Continued Safe Reopening of Institutions” dated 13 September 2022 Department of Health Department Memorandum No. 2022-0501 “Interim Revised Case Definitions for COVID-19” Philippine COVID-19 Living Clinical Practice Guidelines https://www.psmid.org/philippine-covid-19-living-recommendations-3/ Philippine Food and Drug Administration World Health Organization (2023). Infection prevention and control in the context of coronavirus diseases (COVID-19): A guideline https://app.magicapp.org/#/guideline/Lr2a8 World Health Organization. Therapeutics and COVID-19: Living guideline, 10 November 2023 https://iris.who. int/bitstream/handle/10665/373975/WHO-2019-nCoV-therapeutics-20 23.2-eng.pdf?sequence=1 16