New Era University College of Nursing NCM 109-18 Care of Mother, Child, At Risk or with Problems (Acute and Chronic) Module 3: Nursing Care of the High-risk Pregnant Client (Medical Complications in Pregnancy) 3. Perinatal exposure of an infant to infected maternal secretions through birth or breastfeeding B. Diagnosis 1. Tests used to determine the presence of antibodies to HIV include enzyme-linked immunosorbent assay (ELISA), Western blot, and immunofluorescence assay (IFA). 2. A single reactive ELISA test by itself cannot be used to diagnose HIV, and the test should be repeated with the same blood sample; if the result is again reactive, follow-up tests using Western blot or Immunofluorescence antibody test (IFA) should be done. 3. A positive Western blot or IFA is considered confirmatory for HIV. 4. A positive ELISA that fails to be confirmed by Western blot or IFA should not be considered negative and repeat testing should be done in 3 to 6 months. C. WHO disease staging system for HIV infection and disease (September 2005) Stage I: HIV disease is asymptomatic and not categorized as AIDS Stage II: includes minor mucocutaneous manifestations and recurrent upper respiratory tract infections Stage III: includes unexplained chronic diarrhea for longer than a month, severe bacterial infections, and pulmonary tuberculosis Stage IV: includes toxoplasmosis of the brain, candidiasis of the esophagus, trachea, bronchi or lungs and Kaposi's sarcoma; these diseases are indicators of AIDS. D. Assessment Early 1. Fever 2. Headache 3. Tiredness 4. Enlarged lymph nodes Late 1. Lack of energy 2. Frequent fevers and sweats 3. Persistent or frequent yeast infections (oral or vaginal) 4. Persistent skin rashes or flaky skin 5. Pelvic inflammatory disease in women that does not respond to treatment 6. Short-term memory loss 7. Weight loss E. Interventions 14