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MHD W3

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PSYC11412: Foundations in Mental Health and Distress
The role of life circumstances in
mental health
Dr Ming Wai Wan
SENSITIVE
TOPICS
•
These lectures will inevitably explore sensitive
topics that can be emotional/triggering (e.g.
examples of life experiences that some individuals
might regards as painful or traumatic
•
Some individuals might feel that the content of this
lecture “hits home”
•
Please ensure that you do what works best for you
in terms of looking after your well-being, e.g. take
a 5-minutes break; familiarise yourself with the
lecture material beforehand etc.
•
Feel free to approach me, your academic
advisor/year tutor, or the University’s well-being
services (e.g. Counselling Service and Mental
health services https://www.counsellingservice.manchester.ac.uk).
Overview
• Whether, how, and which kinds of
stressful/traumatising life experiences impact on
mental health
• An overview of the research and the limitations
• Whether structural factors, such as
discrimination and inequality, affect mental
health
• Can adverse life experiences be positive for
mental health? Are there protective factors?
problem with the term ‘traumatic’
we’re not always sure if the specific individual is traumatised
or they’ve just experienced an event that is commonly inducing trauma
Adverse (or potentially traumatising) life experiences
• Most of us experience have experience of 1+ ‘potentially
traumatising’ life experiences (PTEs):
• 90% of older US adults (mean 60 years) (Ogle et al., 2013)
• 81% of Dutch adults (De Vries & Olff, 2009)
• 70% based on combined samples from 24 countries using the
World Mental Health Survey (N = >68k)
• And 30.5% had 4+ PTEs (Benjet et al., 2015)
• PTEs can lead to post-traumatic stress in the immediate
aftermath of the event
• But most people exposed to stressful – even traumatic – events
do not develop a mental disorder
but the likelihood is increased
Estimated % who develop
PTSD following…
Severe beating /
physical assault
31.9%
Stabbing or
shooting
15.4%
Estimated % who had
depression following…
Losing spouse
later in life
13%
Adverse experiences increase risk of MH difficulties
• Major stressful life events prospectively predict depressed affect,
anxiety and fear
• This in turn raises risk of depression (Gotlib & Joorman, 2010;
Hammen, 2016).
• Individuals with depression are at 2.5 - 9.4x as likely to have
experienced a major stressful life event before the first onset of
depression (Kendler et al., 2000; Slavich & Irwin, 2014).
correlation between major stressful life events & first onset of depression
can’t say that it’s a cause!!! (depression might have happened anyway even w/out the event
• PTSD by definition is a mental disorder that arises from a traumatic
life experience
by default PTSD requires an identifieble stressor
“i’ve experienced trauma”
referes to an experience of a typically traumatising event
Events
Frequently used terms:
• Adverse life experiences
• Negative / stressful life events
• Traumatic experience / ‘trauma’ (more
accurately a ‘potentially traumatising event’
General definition: A group of events that are
typically extremely stressful or negative if
experienced or witnessed, which are Known to
be physically / psychologically threatening to
self (or loved ones)
While all these can be traumatising, they do
not necessarily lead to psychological trauma
Adverse childhood experiences
(ACES – when in childhood)
predictor of physical/mental health
worse ACES ~= worse physical/mental health
General definition:
(Psychological) trauma (‘traumatised’): A
general term referring to an emotional (&
physiological) response to an intensively
distressing event/s, which can have lasting
mental, emotional, physical and social
impacts
What is trauma?
Impact of self
‘i’m traumatised’
experiencing the aftereffect following a
potentially traumatising event
Post-traumatic stress disorder
(PTSD): A DSM diagnosis
not a DSM diagnosis, but people are fighting it to be
Developmental trauma: Childhood trauma (usually repeated/prolonged)
characterised by various forms of dysregulation (affective, behavioural,
attentional, physiological), but often does not fit the PTSD criteria based on
the defined stressor(s) (low or no recollection); neither are there some PTSD
symptoms; e.g. flashbacks (Van der Kolk, 2005)
Stressors, PTEs and mental health difficulties
• (Potentially) traumatising experiences are more likely to develop into mental health
difficulties are (on average) more likely to develop when traumatic experiences are:
more likely to develop MH
difficulties following a traumatic
interpersonal experience
rather than experiencing a natural
disaster
• Repeated/multiple or prolonged; when ”escape” is difficult or impossible
• Interpersonal (they involve people close to the person or meaningful others)
• Happen at critical developmental stages (childhood, adolescence and ‘life transitions’)
• Stress proliferation theory/effects (Pearlin, 1981; LeBlanc et al., 2015)
• A stressor/set of stressors expand or develop within and beyond a situation
• Result in new stressors (that were not originally present)
• Thus, early stressors in life may increase risk to mental health difficulties via the
proliferation of further stressors
• Mothers’ own adverse childhood experiences were associated with child mental health
difficulties at 5 years, mediated by maternal depression and attachment difficulties
(anxiety/avoidance) (Cooke et al., 2019) – Suggests that trauma can have indirect
intergenerational effects on mental health
mother’s ACEs —> metarnal depression —> child attachment insecurity —> child MH difficulties
How common are Adverse
Childhood Experiences (ACES)?
• ACES are studied by asking adults about how often
they had various negative childhood experiences
• High prevalence of at least 1 ACE: 47% British adults;
50% Korean adults, 25% Swedish adults
• 8% of UK adults have experienced 4+ ACEs
• Much higher rates of 1+ ACEs in Low and Middle Income
Countries (LMIC)
• E.g. 90/77% young Malawian men/women, >80%
Brazilian adolescents, 75% in Philippines and China
• Research shows that girls tend to experience more
ACES than boys and different types of ACE.
ACEs and common mental health difficulties
Systematic reviews and meta-analyses found a strong association between the number of ACEs and risk of
‘common’ mental health difficulties in a dose-response relationship:
Merrick et al.’s (2017) Californian study
(N = 7465) found a dose-response
(graded) relationship between number
of ACEs and depressed affect
Adjusted odds ratios (i.e. Increased odds/risk)
Anxiety
Self-harm
Suicidality
Drug use
Alcohol use
Mental
health
related
behaviour
Psychosis
Borderline
personality
disorder
Bipolar
disorder
Number of ACEs were
associated with other common
mental health difficulties…
(Merrick et al. 2017)
On average, people exposed to childhood adversities
are 3x more likely to develop psychosis (Varese et al., 2012)
Up to a third of cases of psychosis could be attributable
to the impact of childhood adversities (Varese et al., 2012)
Those exposed to 5 types of childhood trauma: 53x
more likely to have experienced psychosis (Shevlin et al.,
2007)
ACEs and mental health
• Regarding types of ACE, emotional abuse may be particularly
- self report
destructive to mental health. 36%
partly due to co-occurrence with other types of abuse/maltreatment
• Meta-analysis of 97 studies by Palmer-Klaus et al. (2015) found:
• Bipolar disorder: 4 times more likely than non-clinical controls to
report childhood emotional abuse
• Borderline personality disorder:14x more likely than controls to
report childhood adversities; 38x more likely to report childhood
emotional abuse
• Merrick et al. (2017): The strongest effect of any single ACE on outcomes
measured was emotional abuse on attempted suicide (5.6 times
increased risk)
• Biggest predictors of negative affect (not a diagnosis) are mental
disorder in household, emotional neglect and emotional abuse
How do adverse experiences affect our mental health?
Adverse life experiences
How we perceive / appraise the negative situation
is more important than the objective situation
whether it becomes part of self identity (e.g. shame)
and relates how we view/relate to others (e.g. trust)
All inter-related
Cognitive and
Emotional
-Emotional dysregulation
-Negative beliefs about self,
others and the world
- Sense of threat
-‘Maladaptive’ thinking styles
(rumination, suppression)
There is research evidence
supporting each of these
processes
Physiological
Behavioural
-Stress effects on
neuroendocrine system
(e.g. HPA axis)
-Long-lasting
neurobiological changes
e.g. heightened stress
sensitivity
- Health-harming
behaviours as a way of
coping (alcohol, drug
use, self-harm)
social
- Difficulties in relationships
- Other behaviours as
way of coping
e.g. being aggressive
struggling to regulate your
stress responses
Increased risk of a range of mental health
difficulties
loosing trust for others
indirect impacts:
e.g. drinking alcohol as a way of coping
may influence our relationships with drienf/family
asking adults who recollect/report on their childhood experiences
often might be underreported due to memory/no desire to share private experiences
Research
limitations
Negative life events from a
structural (sociological)
perspective
• The way society is structured contributes to mental health
difficulties through:
opportunities & rewarads for different
• Social inequality unequal
social positions or statues within a group or society
• Poverty (or socioeconomic disadvantage)
• Discrimination (e.g. racism, transphobia, homophobia)
• Discrimination: Unfair treatment or negative attitudes
towards categories of people (based on age, gender,
race/ethnicity, religion, disability, sexual orientation etc.)
• Not always overt; often ‘subtle’ but damaging forms of
singling out members (e.g. limiting access to social
resources)
Negative life events from a structural (sociological)
perspective
• Individuals belonging to ‘minorities’ have elevated mental health
risks: evidence suggests role of discrimination
• Ethnic minorities & psychosis risk (24 studies; Pearce et al., 2019)
• Not explained by immigration
• Young homeless people who report more discrimination report
more psychological distress/suicidal ideation (Narendorf et al., 2022)
• Reasons for discrimination include housing status, sexual orientation,
juvenile justice involvement
• Across Europe (N = 40k), those belonging to more minoritised
‘categories’ have more depressive symptoms
• Effect stronger in Eastern & Southern European countries; Alvarez-Galvez &
Rojas-Garcia, 2019)
• Thus, increasing evidence suggesting a role of discrimination
• But discrimination itself is not in most stressful/negative life event
measures
Poverty and
social inequality
• Poverty and social inequality (i.e. unequal
opportunities and rewards for
different social positions or statuses within
a group or society) are associated with
mental health, both within a nation and
between countries
• Extent of within-country wealth and social
inequality correlates with the incidence of
many mental health issues (see graph)
• Levels of psychotic disorders are 9 times
higher in people in the lowest fifth income
households compared to the highest.
The relationship between lifetime adverse life events &
mental health
Wisbech Carstensen et al. 2020
• Danish study (N > 7000) asked adults about a wide
range of lifetime negative life events (including stress,
violence, bereavement, serious injury) and emotional
distress in the last week
Key findings:
• A dose-response relationship: As adverse events
accumulated (especially 9+ events), emotional
distress increased
• Slight ‘U-curve’ supports a small resilience effect:
low levels of adverse events more protective than no
adverse life events
None
• Seery et al. (2011) found a larger resilience effect for
ALEs and post-traumatic stress symptoms / global
distress
Protective (resilience) characteristics & buffering effects
Positive life experiences and relationships across the lifespan can buffer or counteract the
impact of life adversities (i.e. resilience / protective factors)
Goal
orientation
Confidence,
academic
aspiration, life
satisfaction
Social
support
Sleep
Having the support
of an adult, family
cohesion,
perceived
emotional support,
access to social
support, social
resources
(Only one
study out of
those
reviewed
studied this)
Cognition
and
cognitive
strategies
Greater
perceived selfefficacy/control,
less negative
affectivity, Less
rumination
• Older adults: Life satisfaction and social support important; young people: goals, attachment & IQ
• For marginalised groups, the protective role of community / neighbourhood support is important
Alleviating mental health difficulties after
challenging life experiences
• Access to ‘corrective experiences’ can help survivors
even after developing mental health problems as a result
to life challenges
• Adverse life experiences that threaten our lives and social
role, and how we make meaning out of those events,
can particularly affect mental health
• Re-processing this experience in a safe environment can
help individuals to move on.
• Trauma-informed care encourages mental health
professionals to assume that all individuals who access
mental health services might have experienced important
adverse life events
Therapeutic relationship as source of social and
emotional support
Therapist as a model of self-compassion
Therapist to encourage adaptive coping and
health-promoting behaviours
Therapist to help retrain cognitions
Conclusions
• Most adverse life events do not result mental health difficulties, but risk is
increased, especially if repeated/chronic, interpersonal (esp emotional
abuse), or happen at life transitions / early in life
• Traumatic experience impacts on our emotions, cognitions, behaviours,
relationships and neurobiology
• ACES are associated with a wide range of mental health difficulties and
maladaptive behaviours in a dose-response (graded) relationship
• Negative life experiences may disproportionately happen in certain sections
of society, resulting from how our society is organised structurally
• When working with individuals in distress, provision of ‘corrective’
experience and protective factors help to boost psychological resilience and
prevent, reduce and alleviate mental health difficulties
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