Misoprostol PGE
(Cytotec)
cytoprotection of
the gastrointestinal
mucosa, uterotonic,
diarrhea, and
abdominal pain
diarrhea and
abdominal
pain. ...
previous allergic
reaction or
hypersensitivity to
prostaglandin
Gastrointestinal Agents,
Other; Prostaglandins,
Endocrine
stimulates prostaglandin E1 receptors
on parietal cells in the stomach to
reduce gastric acid secretion. * induce
labor, cause an abortion, and treat
postpartum bleeding due to poor
contraction of the uterus
Butorphanol (Stadol)
confusion,
dysphoria,
hallucinations,
sedation,
euphoria, floating
feeling, headache,
unusual dreams
Drowsiness,
dizziness, blurred
vision, flushing
acute or severe bronchial
asthma in an unmonitored
setting or in the absence of
resuscitative equipment
Opioid Analgesics;
Analgesics, Opioid
Partial Agonist.
The principal therapeutic
action of butorphanol is
analgesia.
Fentanyl (Sublimaze)
interferes with
respiratory
function and
patients with known
intolerance to the drug or
other opioid agonists
pupil reaction
Schedule II controlled
drug substance
slowheartbeat.abn
ormally low blood
pressure.
produces strong analgesia
through its activation of
opioid receptors
Magnesium Sulfate
Depressed
reflexes, flaccid
paralysis,
respiratory
paralysis. Heart
block, cardiac
arrest.
myasthenia gravis, severe
renal failure, cardiac
ischemia, heart block and
pulmonary edema.
Antidysrhythmics, V;
Electrolytes.
Confusion.
dizziness or
lightheadedness.
20
grams/48
hours
reduces striated muscle contractions
and blocks peripheral neuromuscular
transmission by reducing acetylcholine
release at the myoneural junction.
Calcium Gluconate
Assess for cutaneous
burning sensations
and peripheral
vasodilation, with
moderate fall in BP,
during direct IV
500 mg - 2
hypercalcemia,
hypersensitivity to
calcium gluconate, and
sarcoidosis
20 mL)
grams
injection.
calcium salt.
little or no urinating;
swelling, rapid weight
increasing the level of
calcium in the blood or by
binding to excess potassium
or magnesium in the blood.
gain;
Nifedipine
Severe aortic stenosis.
chronic stable
angina,
hypertension.
Unstable angina.
Hypotension.
Heart failure.
calcium-channel
blockers.
Headaches,
Flushing.
inhibits the entry of calcium ions by
blocking these voltage-dependent Ltype calcium channels in vascular
smooth muscle and
cells.
myocardial
Ondansetron (Zophran)
low amount of magnesium in the
blood.low amount of calcium in
the blood.
Monitor
improvement
s in GI
symptoms
low amount of potassium in the
blood.
serotonin 5-HT3
receptor antagonists
headache.const
ipation.
blocking the action of
serotonin a natural
substance that may cause
nausea and vomiting
weakness
Promethazine (Phenergan)
6.25-12.5 mg q8hr)
sedation,
confusion, and
disorientation
in comatose states, and in
individuals known to be
hypersensitive or to have had an
idiosyncratic reaction to
promethazine or to other
phenothiazines.
phenothiazines
drowsiness,
headaches,
nightmares and
feeling dizzy, restless
or confused.
antagonizes the central and
peripheral effects of histamine
mediated by histamine H1
receptors.
Methylergonovine (Methergine)
0.2 mg IM/IV q2-4hr
rapid and sustained
titanic uterotonic
effect which
shortens the third
stage of labor and
reduces blood loss
eclampsia or
preeclampsia (toxemia
of pregnancy
ergot alkaloids
Blood in the urine.
acts directly on the smooth
muscle of the uterus and
increases the tone, rate, and
amplitude of rhythmic
contractions.
change in skin color.
Naloxone (Narcan)
hypersensitivity to
naloxone.
acute opioid
withdrawal
(agitation, nausea,
vomiting, diarrhea,
"goose flesh",
tearing, runny
nose, and yawning)
opiate antagonists
chest pain or
discomfort.difficult
or labored
breathing
attaches to opioid
receptors and reverses and
blocks the effects of other
opioids
Acetaminophen
can cause
hematologic
reactions
red, peeling or
blistering skin.
hypersensitivity to
acetaminophen, severe
hepatic impairment, or
severe active hepatic
disease
analgesics (pain
relievers) and
antipyretics (fever
reducers).
inhibit the synthesis of
prostaglandins in the
central nervous system
rash.
Acetaminophen/codeine (Tylenol
#3)
Bloody or
cloudy urine
children 12 to 18 years of age who
are obese or who have a
neuromuscular disease (disease
that affects the nerves that
control voluntary muscles), a lung
disease, or obstructive sleep
apnea
Nausea, vomiting,
constipation,
lightheadedness,
dizziness, or
drowsiness
Schedule III/IIIN
Controlled Substances
(3/3N)
inhibit the synthesis of
prostaglandins in the
central nervous system
Diphenhydramine (Benadryl)
Documented hypersensitivity to
diphenhydramine.
dizziness, headache,
sedation; paradoxical
stimulation in
children
Premature infants and neonates.
Breastfeeding mothers.
antihistamines
acts as an inverse agonist at the
H1 receptor, thereby reversing
the effects of histamine on
capillaries, reducing allergic
reaction symptoms
Docusate Sodium (Colace)
Hypersensitivity reaction to any of
the docusate ingredients.
Evaluate
therapeutic
response
(decreased
constipation)
Avoid concomitant use of mineral
oil.
stool softener
Anorexia, diarrhea,
and vomiting
lowers the surface tension at
the oil-water interface of the
feces, allowing water and lipids
to penetrate the stool.
measles mumps rubella
risk of febrile
seizures
history of a severe
(anaphylactic) reaction to a
previous dose or to any
component of the vaccine
(such as gelatin or neomycin),
pregnancimmunosuppression.
vaccine
Sore arm from the
shot.Fever.Mild
rash.
after injection, the viruses cause a
harmless infection in the vaccinated
person with very few, if any,
symptoms before they are eliminated
from the body.
Ibuprofen (Motrin)
have a current or recent
stomach ulcer, or you have had
drink plenty
of fluids
one in the past. have
severe heart failure
NSAIDs
Abdominal
pain.
acid or sour
stomach.
inhibit prostaglandin
synthesis rather than simply
to provide analgesia
Oxycodone/acetaminophen 5/325
(Percocet)
can cause
extreme
sleepiness and
lower your
ability to think,
react, and focus.
patients with significant
respiratory depression (in
unmonitored settings or the
absence of resuscitative
equipment) and patients with
acute or severe bronchial
asthma or hypercarbia.
Schedule II
controlled substance.
dizziness,
drowsiness,
feeling tired
inhibition of endogenous
pyrogen action on the
hypothalamic heatregulating centers.
Hydrocortisone w Pramoxine 1%
(Epifoam)
active tuberculosis.
blurred vision,
eye pain, or
seeing halos
around lights
herpes simplex
infection of the eye.
anti-inflammatory
steroids
Burning, itching.
irritatio
anti-inflammatory activity
Ketorolac (Toradol)
contraindicat
ed in nursing
mothers
patients with previously
documented peptic
ulcers and/or GI
bleeding.
NSAIDs.
inhibits key pathways in
prostaglandin synthesis
headache.dizziness.
drowsiness.
diarrhea.
Simethicone (Mylicon)
rash,
itching/swelli
ng
hypersensitivity to
simethicone or any
component of the
inactive ingredients
gastrointestinal agents
severe dizziness,
trouble breathing
changes surface tension of
gas bubbles, allowing easier
elimination of gas
Buprenorphine (Subutex)
hypersensitivity
reaction to it
can lead to
overdose
and death.
mixed opioid agonistantagonists.
headache,
partial agonist at the mu
receptor, meaning that it
only partially activates
opiate receptors
stomach pain
Buprenorphine and Naloxone
(Suboxone)
Problems
with
concentrati
on
patients with a history of
hypersensitivity to
buprenorphine or naloxone
buprenorphine's
opioid
Burning or sore
mouth.
blocks opioid withdrawals
Rhophylac- Rh Immune Globulin
hemolytic reaction may
result if given to Rh-positive
patients
nausea,
dizziness,
headach
immunizing agents.
njection-site pain,
and
malaise
prevents the antibody response
during incompatible pregnancy by
accelerating the phagocytosis of
RBC's and clearance from the
circulation before the recognition by
the immune system
Ferrous Sulfate
Dark or
black poo
iron metabolism
disorder causing
increased iron
storage.
a type of iron
Constipation.
Iron combines with
porphyrin and globin
chains to form hemoglobin
Erythyromycin Opthalmic ointment
mild eye
irritation and
redness
patients with a history
of hypersensitivity to
erythromycin
macrolide antibiotics.
Allergic
reactions
nhibition of protein synthesis by
binding to the 23S ribosomal
RNA molecule in the 50S subunit
of ribosomes in susceptible
bacterial organisms
Hepatitis B vaccine
Additional doses
may be required for
individuals with a
suppressed immune
Anaphylactic reaction to
previous hepatitis B
vaccine
system.
Vaccines, Inactivated,
Viral.
Soreness, redness, or
swelling
stimulates the immune system
to produce anti-HBs without
exposing the patient to the
risks of active infection.
Phytonadione (Vitamin K)
Bluish color of
the fingernails,
lips, skin,
palms, or nail
beds
phytonadione
hypersensitivity, hereditary
hypoprothrombinemia,
heparin over-anticoagulation
a class of medications
called vitamins
hives, itching, skin
rash
acts as a cofactor to an enzyme found
in the liver called gamma glutamylcarboxylase, which converts the
inactive forms of coagulation factors
II, VII, IX, and X into their active
forms.
oxytocin
uterine
hyperstim
ulation
Confusion.convul
sions (seizures
highbloodpressure.pl
acenta previa.a
pregnancy with
more than one fetus.
oxytocic hormones. It
works by stimulating
uterine contractions
increases the sodium permeability of
uterine myofibrils, indirectly
stimulating contraction of the uterine
smooth muscle
Dinoprostone (Cervidil)
Monitor for
allergic reactions
and anaphylaxis,
including
pulmonary
symptoms
fever,nausea,vomit
ing,diarrhea,abdo
minal or stomach
pain,back pain
contraindicated in
prepartum
pregnant patients
because
misoprostol causes
cervical ripening
and can induce
Vaginal
Insert is a
abortion..
prostaglandin,hormo
cases in which there
ne-like substance
is a
stimulates the production of
prostaglandin F2α (PGF2α), which
sensitizes the myometrium to
endogenous or exogenously
administered oxytocin