University of Al-Ameed / College of Medicine Department of Anatomy M.B.Ch.B. M.Sc. Ph.D. Anatomy 1. Describe the anatomy of pharynx: i. Nasopharynx ii. Oropharynx iii. Laryngopharynx 2. Demonstrate the anatomical structure of the Larynx: i. Parts of larynx ii. Cartilages of larynx iii. Neurovascular supply 3. Elucidate the anatomical construction of Thyroid Gland. PHARYNX • It is a musculofascial half-cylinder that links the oral and nasal cavities in the head to the larynx and esophagus in the neck. The pharyngeal cavity is a common pathway for air and 'food'. • Parts of Pharynx: 1. Nasopharynx 2. Oropharynx 3. Laryngopharynx NASOPHARYNX • It is situated above the soft palate behind the nasal cavity. • Boundaries: Superior – skull base Inferior – level of soft palate Anterior – choanae (posterior nasal apertures) Posterior – nasopharyngeal tonsil • Lined with respiratory ciliated stratified squamous epithelium. Contents 1. Nasopharyngeal tonsil (adenoids) 2. Part of Waldeyer’s ring 3. Eustachian tube orifice OROPHARYNX • Behind mouth and tongue • Boundaries: Superior – level of soft palate Inferior – superior edge of epiglottis Anterior – oral cavity Posterior – C2 – C3 • Lined with stratified squamous epithelium Contents • Palatine tonsils • Anterior and posterior tonsillar pillars 3 Sets of tonsils: 1. Pharyngeal Tonsils 2. Palatine Tonsils 3. Lingual Tonsils Palatine Tonsils Lie in tonsillar fossa (between ant. and post. pillars). Anterior pillar (palatoglossal arch) The boundary between buccal cavity and oropharynx. Fuses with lateral wall of tongue. Contains palatoglossal muscle. Posterior pillar (palatopharyngeal arch) blends with wall of pharynx. Contains palatopharyngeus muscle. Blood Supply - Tonsillar branch of facial artery (also lingual/ascending palatine/ascending pharyngeal) - Venous drainage pharyngeal plexus (also paratonsillar vein) Lymph Drainage Lymphatics pierce superior constrictor muscle pass to nodes along internal jugular vein and Jugulo-digastric node (angle of mandible). Laryngopharynx (Hypopharynx) • Below epiglottis • Boundaries: Superior – superior edge of epiglottis Inferior – level of inferior edge of cricoid cartilage Anterior – larynx Posterior – C3 – C6 vertebrae • Inferiorly opens into oesophagus • Lined with stratified squamous epithelium Pharyngeal Musculature They arranged into two groups; Constrictors and Longitudinal. 1. Superior Constrictor 2. Middle Constrictor 3. Inferior Constrictor • Overlap each other • Open anteriorly • Attached posteriorly by median raphe • Gaps provide important routes for muscles and neurovascular tissues. • Above the margin of superior constrictor, the pharyngeal wall is deficient in muscle and completed by pharyngeal fascia. • The tensor and levator palatini muscles of the soft palate descend from the base of the skull and reinforce the pharyngeal fascia. • Between the superior and middle constrictor muscles: stylopharyngeus, muscles, nerves, and vessels between regions lateral to the pharyngeal wall and the oral cavity, particularly the tongue. • The gap between the middle and inferior constrictor muscles allows the internal laryngeal vessels and nerve access to the aperture in the thyrohyoid membrane to enter the larynx. • The recurrent laryngeal nerves and accompanying inferior laryngeal vessels enter the larynx deep to the inferior margin of the inferior constrictor muscle. Pharyngeal Musculature The longitudinal muscles: 1. Stylopharyngeus 2. Salpingopharyngeus 3. Palatopharyngeus Pharyngeal Musculature Muscle Origin Insertion Innervation Function Stylopharyngeus Medial side of base of styloid process Pharyngeal wall Glossopharyngeal nerve Elevation of the pharynx Salpingopharyngeus Inferior aspect of pharyngeal end of pharyngotympanic tube Pharyngeal wall Vagus nerve Elevation of the pharynx Palatopharyngeus Upper surface of palatine aponeurosis Vagus nerve Elevation of the pharynx; closure of the oropharyngeal isthmus Pharyngeal wall Pharyngeal Blood Supply Arterial – Superior Thyroid Artery – Ascending Pharyngeal Artery – Ascending And Descending Palatine Artery – Branches of lingual, facial and maxillary arteries – (External Carotid Artery) Venous – Pharyngeal Venous Plexus – (Internal Jugular Vein) Pharyngeal Nerve Supply Motor • Vagus (X) • Glossopharyngeal (IX) • All muscles of the pharynx are innervated by the vagus nerve [X], except for the stylopharyngeus, which is innervated by a branch of the glossopharyngeal nerve [IX]. Sensory • Nasopharynx – Maxillary division of Trigeminal (V2) • Oropharynx - Glossopharyngeal (IX) • Laryngopharynx – Vagus (X) • The larynx is a hollow musculoligamentous structure with a cartilaginous framework that caps the lower respiratory tract. • The cavity of the larynx is continuous below with the trachea, and above opens into the pharynx. Functions Respiration (open valve) Phonation (partially closes valve) Protecting trachea/bronchial tree (swallowing) Cough reflex Parts of Larynx 1. Supraglottis Inferior surface of epiglottis Vestibular folds (false cords) 2. Glottis Vocal cords (including 1cm inferiorly) 3. Subglottis Down to lower border of cricoid cartilage Larynx Main Structures 1) Epiglottis 2) Thyroid cartilage 3) Cricoid cartilage 4) Arytenoid cartilage (paired) 5) Cuneiform cartilage (paired) 6) Corniculate cartilage (paired) – Vocal Cords Epiglottis • Leaf shaped plate of elastic fibrocartilage • Attached posterior to thyroid cartilage by thyroepiglottic ligament • Vallecula – depression between tongue base and epiglottis Thyroid Cartilage • Largest cartilage comprising two lamina • Laryngeal prominence (‘Adam’s Apple’) • Superior & inferior thyroid horns (hyoid and cricoid respectively) Cricoid Cartilage • Most inferior cartilage, completely encircles the airway • Signet ring shape • 2 articular facets on each side – Superolateral surface for arytenoid cartilage – Lateral surface for the medial surface of inferior horn of thyroid cartilage Arytenoid Cartilage • Pyramid shaped • Concave base articulating with cricoid • Involved in vocal cord movement Vocal Cords Laryngeal Blood Supply Arterial • Superior Laryngeal Artery (Superior Thyroid Artery) • Inferior Laryngeal Artery (Inferior Thyroid Artery) Venous • Superior Laryngeal Vein • Inferior Laryngeal Vein Laryngeal Nerve Supply Superior laryngeal nerve – Deep to carotid arteries – Internal – pierces thyrohyoid membrane – External – deep to superior thyroid artery, supplying cricothyroid muscle Recurrent laryngeal nerve – Ascends in the tracheo-oesophageal groove – Right – under subclavian artery – Left – under aortic arch – All muscles of the larynx are supplied by recurrent laryngeal nerve, except the cricothyroid which is supplied by external laryngeal nerve. Recurrent Laryngeal Nerve • It is endocrine gland located anteriorly in the neck, begin as pharyngeal outgrowth that migrate caudally to its final position as development continue. • It is large unpaired gland consists of two lateral lobes and connecting isthmus in front of 2nd. and 3rd. tracheal cartilage. • Lying deep to the sternohyoid, sternothyroid, and omohyoid muscles, the thyroid gland is in the visceral compartment of the neck. • The lower pole of the thyroid gland extends along the side of the trachea as low as the sixth tracheal ring 1 2 3 4 5 6 • The thyroid gland is very vascular • The vessels lie between the capsule and the pre-tracheal fascia. • In some pathological conditions such as thyrotoxicosis, owing to its high vascularity, the blood flow can be heard with a stethoscope as a bruit • Two major arteries: A. Superior thyroid A.: first branch of external carotid A. B. Inferior thyroid A.: branch of thyrocervical trunk which arise from the first part of subclavian A. C. Occasionally a third small artery arise from brachiocephalic trunk called Thyroidea ima artery on the anterior surface of trachea. • Three veins drain the thyroid gland: A. the superior thyroid vein primarily drains the area supplied by the superior thyroid artery. B. the middle and inferior thyroid veins drain the rest of the thyroid gland. • The superior and middle thyroid veins drain into the internal jugular vein and the inferior thyroid veins empty into the right and left brachiocephalic veins, respectively. • The thyroid gland is closely related to the recurrent laryngeal nerves. • They pass deep to the posteromedial surface of the lateral lobes of the thyroid gland and enter the larynx by passing deep to the lower margin of the inferior constrictor of the pharynx.