Name:
DNA Replication Activity
DNA Replication - Labeling (with word bank)
DNA polymerase
Replication Fork
DNA Ligase Okazaki fragment
Single Stranded Binding Proteins Leading Strand
Helicase
DNA Primase
Lagging Strand
Identify the structure based on its description.
1. _____________________________ Enzyme that unwinds DNA
2. _____________________________ Fragments of copied DNA created on the lagging strand
3. _____________________________ The strand that is copied in a continuous way, from the 3’ to 5’
direction
4. _____________________________ Binds Okazaki fragments
5. _____________________________ Builds a new DNA strand by adding complementary bases
6. _____________________________ Stabilizes the DNA molecule during replication
Name:
7. _____________________________ Strand that is copied in fragments because it is traveling away
from helicase
8. _____________________________ Initiates the synthesis DNA by creating a short RNA segment at
replication fork
In the drawing below, the small segment of plant DNA is shown after the two strands of the DNA
molecule have been separated. Your job is to play the role of DNA polymerase and create the new
matching strands of DNA to make two pieces of double-stranded DNA in the drawing below. Use the
base pairing rules to create the new complimentary strands of DNA (the “new strand” highlighted in
red).
Template Strand
New Strand
As specifically as possible, explain what would happen in terms of DNA synthesis if you created mutant
cells in which you knocked out (disabled) specific enzymes associated with replication.
1. DNA polymerase knockout
2. SSBP knockout
Name:
3. Helicase Knockout