The principles of science are based on the systema c observa on, experimenta on, and analysis of natural phenomena to develop knowledge and understanding of the physical, biological, and social world. These principles include empiricism, which emphasizes the importance of collec ng data from direct observa on and experience; falsifiability, which states that scien fic claims must be testable and poten ally disprovable; objec vity, which requires the elimina on of personal bias in the process of inquiry; and reproducibility, which demands that scien fic experiments and findings can be replicated by other researchers. These principles provide a founda on for the advancement of scien fic knowledge and the development of theories and models that explain natural phenomena.