Pharmacology
 It is the science that deals with the study of drugs,
including their origin, nature, chemistry, uses and
beneficial and adverse effects. It includes the study of
substances that bind to regulatory molecules and
activate or inhibit normal body processes.
History
 Hippocrates
 Theophratus
 Alexandria (331 BC)
 Sustra (hindus medical text)760 herbs with their
habitat and harvesting time
 Shen Nung (2735 BC)
 father of chinese materia medica
 Author of Pen taao
 Roman period Celsus (25 BC to 50 AD)
 Writer of a book one part of which was on therapeutics
consisted of 28 chapters
 Dioscorides included aconite, dill, anisi, juniper, wild
liquorice
 Dioscorides emphasized on the signs of early
adulteration of the drug
 White poppy
 Galen (130-200 AD)
 30 books
 Pure drug and handling
 Preparation of pure drug from crude drug e.g, tincture,
fluid extracts and glaneicals
Arabs
 Castor oil
 Musk
 Ambergis
 Camphor
 Senna
 Nux vomica
cathartic
cerebral & opthalamic diseases
cramps, heart diseases, brain
disorder
vertigo, cholera, haemorrhage
cathartic
emetic
 Abu Baker Muhammad Ibn Zakaria Al Razi (850-93)
mercurial ointment
 Al Zahrawi (936-1013) author of Al-Tasrif
 Abu Ali Hussain Ibn Sina(980-1037)
 Al-Qanun Fi Tibb, Kitab Al Shifa
 Digitalis and fox gloves were popular in 18th century
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when William Withering published it
1st pharmacopoeia published in 19th century
Anesthetic 1776 & 1831
Paul Ehrlich (1854-1915)introduced chemotherapeutic
agent
In the 19th century drugs were isolated