Drug Name Echinacea Used for Boost immune system Side Effects Hepatotoxicity: use for only 10-14 days no more than 8 weeks Renal impairment (BUN, Creatinine, UOP) D/D Interaction Other drugs or conditions that also affect liver function like acetaminophen, cirrhosis, hepatitis Monitor ALT/AST Garlic Lower cholesterol Lower Triglycerides Act as anticoagulant Good compliment to cardiovascular health Increased risk of hypoglycemia with insulin and diabetic agents Don’t take with other anticoagulants (bleeding risk), garlic, ginger, gingko Ginseng Increase Stamina Boosts cognitive functioning Stimulates sympathetic nervous system: increased BP, HR Digoxin Toxicity Decreases effectiveness of anticoagulants Lower Triglycerides and increase HDL Elderberry Decrease length and severity of viral illness (colds and influenza) Safe, very few side effects Caffeine can increase adverse effects No concerning drugdrug interactions May also prevent Antiinflammatory/Antioxident St. John’s Wort Used as antidepressant Photosensitivity Decreased effect of Warfarin (clot/ low PT/INR) Don’t use with other antidepressants Kava Kava Use to calm Liver failure reported, changes serotonin, melatonin levels in the brain, visual, mild GI disturbances Don’t use with other CNS depressants, if taken with Alprazolam make cause coma Bleeding Anticoagulants and antiplatelets- increase bleeding risk. Digoxin toxicity Ginkgo Biloba Licorice Improve memory and Cognitive functioning People take it for PUD but it can actually cause Ephedra (ma haung) ulcers in high doses. Used as an appetite suppressant Significant cardiovascular effects (MI, dysrhythmias, sudden cardiac death) Increases risk of toxicity: Theophylline Digoxin Caffeine increases risk of adverse event 1. Herbals are not regulated by the FDA drug approval process. Dietary Supplement Health and Education Act (DSHEA) a) Do not require testing before marketing b) Efficacy does not have to be demonstrated c) Do not have to prove safety d) No regulation about accuracy of label 2. There are many reasons that patients turn to Herbals; healthcare providers must directly ask about herbal medications. Patients often do not reveal they are taking them. 3. Nurses and healthcare providers should educate patients AND be aware of peer reviewed data bases (IBIDS/CARDS) where they can find reliable literature about herbals. 4. The Dietary Supplement Verification Program (DSVP) and ConsumerLab: Quality Product Seal provide voluntary oversight for herbals. 5. Know the medications that must be discontinued before surgery (Not the timing). Know in general terms that herbals can cause cardiovascular problems (dysrhythmias), increased sedation, bleeding (or clotting), electrolyte disturbances, glucose imbalances, and immunosuppression (poor healing).