Gene Editing Derek Carter Younes Spacer CRISPR Clustered Regularly Interspaced Short Palindromic Repeats Spacer ATTGTTA TAACAAT Palindromic Repeat “ROTATOR” The Components ● ● ● Cas9 Protein Helicase Nuclease gRNA dsDNA Alternatives? Adenine Base Editing Cytidine Base Editing Prime Editing Conclusion