Peds Clerkship Review questions A 1-week-old baby is brought to the ED for worsening vomiting for the last day. Baby has been vomiting almost every feed and some episodes the vomitus is green in color, although most have been white. He was born full-term and had an uncomplicated pregnancy and delivery. Was observed in the Nursery for 24 hrs and discharged. Vitals show temp of 100.0 F, HR 180/min, RR 30/min, and BP is 65/40. He appears lethargic with abdominal distension and appears to be tender to palpation. On rectal exam, gross blood is noted. An upper GI series with barium contrast is done and is shown. Which of the following events most likely explains the patient’s presentation? a) Failure of proximal bowel cannulization b) Abnormal migration of ganglion cells in the colon c) Abnormal rotation of the bowel during development d) Occlusion of a segment of small bowel intestinal lumen e) Abnormal exocrine secretion from the pancreas A 3yo F is brought to the ED for progressively worsening cough for the last 10 days. She has coughing spells which last for about 2-3 minutes at a time. The patient occasionally vomits following the episodes of cough. Lungs are clear to auscultation; you notice the patient has a runny nose and hear a “whoop” sounding cough. No report of fever at home. Vitals are normal, and the patient is generally well-appearing otherwise. She has shown ability to drink in the ED without vomiting. There is a new 2-month-old baby in the home. What is the best next step in management? a) b) c) d) e) Providing oxygen for comfort to the patient Vaccination of the patient Antibiotic administration to the baby Counseling the family to separate the two siblings in the home Hospitalize the patient due to risk of dehydration or worsening respiratory status A 4-year old boy presents with periorbital swelling and abdominal distension with fluid-wave 5 days after recovering from an upper respiratory infection with sore throat. Vitals are normal, and on exam breath sounds are diminished on the right side. Labs show: WBC 5000 Hgb 11.5 Na+ 130, K+ 4.3, Cl- 110, CO2 22, glucose 100 BUN 6, Cr 0.5 Plts 250k UA shows 4+ protein, no RBCs/WBCs/casts/glucose/ketones/leukocyte esterase/nitrites. What is the most likely diagnosis? a) Minimal change disease b) Focal and segmental glomerulosclerosis c) IgA nephropathy d) Post-infectious glomerulonephritis e) Lupus nephritis A 7-month-old female is brought to the physician for fever. Urinalysis shows 30-50 WBCs/hpf, positive leukocyte esterase and nitrites and Urine Culture grows Klebsiella pneumoniae. Looking back her records, you see she had a febrile UTI 3 months ago and renal ultrasound was done which showed normal kidneys. She was treated with antibiotics at that time. Which of the following of is the most appropriate next step? a) b) c) d) e) Observation for recurrent symptoms Repeat Urine culture in 3 months Intravenous pyelography Cystoscopy Voiding cystourethrography Since birth, a 48-hour-old newborn has had poor urine output mostly consisting of dribbling. He was born full term to a 27-year-old primigravid woman following an uncomplicated pregnancy and delivery. The newborn has been feeding well on formula and appears well-hydrated and well-appearing. On exam, there is a midline, firm, mass palpated in the lower abdomen. He is not circumcised. Labs show: Na+ 135, K+4.5, Cl- 105, HCO3- 22, BUN 5, Cr 0.4, glucose 84. UA: pH 6, spec grav 1.009, protein trace Which of the following is the most likely cause of his poor urine output? a) Glomerulonephritis b) Posterior urethral valves c) UTI d) Vesicoureteral reflux e) Phimosis f) Early onset sepsis A 3-year-old girl is brought to the ED for acute onset fast breathing and shortness of breath. Her temperatures is 37o C, pulse is 110/min, respiratory rate is 30/min, and blood pressure is 120/80. The lungs are clear to auscultation. Percussion of the right side of the chest shows hyperresonance. Chest Xray shows slight hyper-expansion of the right lung compared to the left lung. Oxygen is administered via face-mask. Which of the following is the best next step in management? a) b) c) d) e) CT scan of the chest Tube thoracostomy Needle decompression Bronchoscopy Administration of hyperbaric oxygen A 5-week-old female is brought to the ED by parents due to worsening vomiting which has become more forceful the last 5 days. She appears hungry and when fed, drinks 2 ounces within 5 minutes, but then proceeds to vomit almost the entire amount out 15 minutes after feeding. She was born at 41 weeks gestation without pregnancy nor delivery complications. She is not in day care and there are no sick contacts. Her temperature is 37oC, pulse is 190/min, respiratory rate is 34/min, and blood pressure is 65/55. Her oral mucosa is dry. She had 1 wet diaper in the last 24 hrs. What is the most likely set of electrolyte findings you will see? a) b) c) d) e) Na+ 145 136 135 145 140 K+ 6 4.0 4.2 5 4.5 Cl112 85 86 112 105 pH 7.48 7.40 7.51 7.50 7.25 A 6-month-old boy is brought to the ED due to 4-week history of abnormal movements that seem to occur in clusters when waking up from sleeping. No real association with feedings but has vomited occasionally after these episodes. They are becoming more frequent and consists of sudden flexion of the head/neck with extension of both arms and legs. On exam there is a 1/6 systolic murmur heard at the left sternal border and 3 areas of skin hypopigmentation that are flat, which parents state are birth marks. His father has mild mental impairment and suffers from seizures. Which of the following is the appropriate first-line treatment? a) b) c) d) e) Benzodiazepine Proton pump inhibitor or H2-receptor antagonist ACTH injections Vigabatrin Counseling on reflux precautions An 8-year-old girl is brought the physician because of pallor and easy fatiguability for the past 2 months. Her symptoms began after an upper respiratory tract infection. She was adopted, and her family history is unknown. She appears pale. The spleen tip is palpated 2 cm below the left costal margin. Her hematocrit is 28%, and reticulocyte count is 7%, with 3+ spherocytes. Splenectomy is most likely to prevent which of the following complications? a) b) c) d) e) Cholelithiasis Esophageal varices Overwhelming sepsis Painful crises Pancreatitis A previously healthy 30-month-old girl is brought to the physician because of a firm mass in the left flank. She has constipation but no other symptoms. The child appears healthy but pale, and a discrete mass is palpated in the left flank. Ultrasound shows a normal right kidney, and a left kidney with a mass distorting the collecting system. Examination of the bone marrow is normal. Urinalysis shows no WBC/hpf and 20-30 RBC/hpf. Which is the following is the most likely diagnosis? a) b) c) d) e) Autosomal dominant polycystic kidney Multicyclic dysplastic kidney Nephroblastoma (Wilms tumor) Neuroblastoma Renal cell carcinoma A 17-year-old female who emigrated from Indian subcontinent presents with a painless lesion on the vulva. She is sexually active with 2 male partners and has had sex without consistent use of condoms. There is an elevated, round lesion on the right labium without discharge nor bleeding, measures about 1cm in diameter. Which is the most likely organism? a) b) c) d) e) f) g) h) Chlamydia trachomatis Gardnerella vaginalis Haemophilus ducreyi Herpes simplex virus Human papillomavirus Neisseria gonorrhoeae Treponema pallidum Trichomonas vaginalis A 8-year-old girl is brought to the physician because of worsening gait and rash for the last 3 days. Rash started on the ankles bilaterally and seems to be spreading upward. It is non-blanching in nature. She has knee and ankle pain and is unable to bear weight on her feet due to pain. She had a low-grade fever and fatigue 1 week prior to these symptoms. On exam, the rash is raised and there are areas where they appear purpuric in nature. Other than temperature of 100.7oF, rest of vitals are normal. What is the most likely diagnosis? a) b) c) d) e) f) Ankylosing spondylitis Behcet syndrome Dermatomyositis IgA vasculitis Juvenile idiopathic arthritis Kawasaki disease g) psoriatic arthritis h) reactive arthritis i) sarcoidosis j) Sjogren syndrome k) systemic lupus erythematosus l) systemic sclerosis (scleroderma) A previously healthy 3-year-old female presents with crying, fast breathing, and drooling 20 minutes after being found next to a bottle of drain cleaner by her parents. Her vitals show temperature of 38o C, HR 120/min, RR 42/min and blood pressure 120/80. She has blisters on the tongue and lips and exhibiting stridor on exam. After stabilization of the airway, what is the best next step? a) Insertion of NG or orogastric tube b) Calling Social work or Child protective services for concerns of abuse/neglect c) Esophagography d) Lateral X-ray of the neck and soft tissues e) Endoscopy A full-term baby is born via spontaneous vaginal delivery and has respiratory distress and perinatal depression immediately after birth. There is terminal meconium noted on the skin and fingernails. She appears cyanotic and administration of positive-pressure ventilation does not improve clinical condition and she is intubated and brought to the NICU. A chest x-ray will show what findings if the etiology was meconium aspiration syndrome? a) Coarse irregular infiltrates and hyperexpansion of lung fields b) Granular appearance of the parenchyma with air bronchograms c) Prominent perihilar streaking in the interlobular fissures d) Cardiomegaly with clear lungs e) Lack of pulmonary marking extending to the periphery with tracheal deviation A 7-year-old boy is brought into the ED for neck stiffness and lethargy and is subsequently admitted to the ICU for fever and hypotension from septic shock. On exam there is purpuric lesions over the trunk and extremities and are nonblanching in nature. Blood and CSF gram stain both show Gram negative diplococci. What is the most likely underlying cause of this patient's condition? a) b) c) d) e) f) AIDS T lymphocyte dysfunction X-linked agammaglobulinemia Complement deficiency IgA deficiency Wiskott-Aldrich Syndrome A 5yo boy is brought to the ED by his parents because of left hip pain for 2 days and an associated limp for the past 4 days. One week ago, he had watery stools and temperatures to 100F; these symptoms resolved within 2 days. There is no history of trauma or recent immunizations. He is otherwise healthy, and his immunizations are up-to-date. He appears alert. His temperature is 96.8F, pulse is 90/min, RR 18/min, and BP is 110/75 mmHg. The left hip is not swollen or erythematous, but there is pain with movement and weight bearing. ESR is 28 mm/h. US of the left hip shows a small effusion. Which of the following is the most appropriate pharmacotherapy? a) b) c) d) e) Oral acyclovir Oral clindamycin Oral ibuprofen IV ceftriaxone IV vancomycin A previously healthy 4-month-old girl is brought to the ED in January because of cough and poor feeding for 2 days. She is still urinating and making tears. She initially had a fever of 100.8 F, but has been afebrile for the past day. She appears mildly ill. Her temp is 99.5F, pulse is 140/min, and RR 56/min. Exam shows pink tympanic membranes with good mobility. There are mild intercostal retractions, and diffuse bilateral crackles and wheezes are heard. Pulse ox on room-air shows an oxygen saturation of 84%. Which of the following is the most appropriate next step in management? a) b) c) d) e) f) g) h) Arterial blood gas analysis Culture of the pharynx for bacteria Viral culture of the respiratory secretions CXR Neck XR Administration of an inhaled bronchodilator Administration of oxygen Subcutaneous administration of epinephrine An 8yo girl is brought to the physician because of a diffuse rash for 24 hrs. She has had cough, congestion, eye discharge, and fever for 4 days. The rash initially began on her face and chest but has spread to involve her abdomen, back, and lower extremities. Her temp is 102.1 F, pulse is 100/min, RR 16/min, and blood pressure is 115/70 mmHg. Exam shows a diffuse red, macular and popular rash involving the face, trunk, and extremities; there are no lesions on the palms or soles. Which of the following is the most likely diagnosis? a) b) c) d) e) Ehrlichiosis Henoch-Schonlein purpura Id reaction Kawasaki Disease Pityriasis rosea f) Rocky Mountain spotted fever g) Rubeola h) Scabies i) Scarlet fever j) Staphylococcal-scaled skin A 16-year-old girl is brought to the office for a well-child visit. She has no symptoms and is otherwise healthy with a BMI in normal range. She has started playing basketball for the school team for the last 4 months and has practice 5 times/week. She has lost 2 lbs since the start of basketball season when she came into the office for Sports clearance. What is the best next step of management for this patient? a) b) c) d) e) Urine gonorrhea/chlamydia testing by PCR No intervention, follow-up at next visit Follow-up for weight check in 3 months Screen for developmental delay Thyroid studies A 7-year-old boy is brought to the ED 30 mins after the onset of confusion, altered mental status, headache, weakness, shortness of breath. When his mother returned from home, she found him in front of the TV with a space heater. What is the most appropriate treatment? a) b) c) d) e) f) g) h) i) Acetylcysteine Amyl nitrite Atropine Deferoxamine Dimercaprol Methylene blue Naloxone Oxygen Vitamin K A 6-year-old girl is brought to the office by her mother for compulsive eating beginning at the age of 3. She was born following an uncomplicated pregnancy, delivery was complicated by breech presentation. During infancy, the patient had hypotonia. She began walking at the age of 2 years and talking at the age of 2.5 years. The patient lives with her mother and older sister. She is at the 52nd percentile for height and 98th percentile for weight. Her temp is 37o C, HR 92/min, RR 20/min, blood pressure is 86/50. Exam shows almond-shaped eyes and prominent nasal bridge. She has delayed speech and motor development. Which of the following is the most likely diagnosis? a) b) c) d) e) f) Angelman syndrome Down syndrome Fetal alcohol syndrome Prader-Willi syndrome Rett disorder Williams syndrome A 16-year-old girl is brought to the physician by her mother due to not having a period. She is otherwise healthy and in no distress. She is 5ft 7in tall and 120lbs, BMI is 19kg/m2. Breast development is Tanner stage 4 and there is minimal axillary and pubic hair development. Pelvic exam shows normal external female genitalia. The cervix is not visible, and no pelvic masses are palpable. What is the most appropriate next step in management? a) b) c) d) e) Follow-up exam in 6 months Karyotype analysis Measurement of serum estrogen concentration MRI of the pituitary gland Estrogen therapy Amenorrhea workup