Dr .N iha lG ab r Topic 8 Animal Transport Dr. Nihal Gabr 22/11 Dr .N iha lG ab r Part 1 animal transport Dr. Nihal Gabr Lichambersgm -2 2 upper pulmonary Lower centrioles Atia . artery (aorta) artery 4BLooduesseligmsemi.lu . ( value tricuspid) atrium atrium ¥1 ue¥i - op b # veins vein (pulmonary arteries bein) aorta enacaua Pulmonary .cm?Ulmonayoein amount value . 'B'"""" artery gayg.yqenf.ge?tttkBmcf..n iha atrioventricular R & Dr .N Cava t . lG value (vena bein Semilunar value . ab r nar - septum - trio ventricular value arteries semilunar values . - * LORD left oxygenated In vein • Away Artery ⑨ right deoxygenated . Atrium @ ventricle a . artery arley Rd vein value • RA - atrioventricular value = Right ventricle - - Ru Dr .N tricuspid LA f tu iha . win • lG Right atrium ' . sea . R value Eo ab r Semilunar semilunar - left atrium left atrioventricular value left ventricle - Bicuspid . . lG iha Dr .N RA LA AU lo ab r lG iha Dr .N ab r In → vein → Atrium Aways Arley → ventriculi → . Vena s Cava * 14 potent A @ * iha Dr .N @ Ru . o - lG ra . pulmonary vein ab r I.A itnouenticukr Uuluectncuspid ) aorta " KEEL:* LU m > €÷÷:::::...÷g T Aorta artery 02 Oz L 02 : ÷. ÷f÷÷÷÷÷nfige.ba?shepahcarleyuTMgexcgsoaqeucoaeqgen vein > y ft R Oz lG : o iha :* r ' N liver . - Dr .N se Coz kenqsjmpuimf.FM Oz ab r T septum 7 259140k Systemic Souci circulation excess amino acids → deamination 3.out . i n #staexa: s o: : m : n algtmi i iei i smu . excess < Renal . Renaja¥_ kidney : Flow of blood in the heart Explain how the blood coming from the body reaches the lungs Uenacaua > venacauu ② g. A Pulmonary artery ⑦ - 8) LA Ru LU , s Aorta 3 . RE , ab r artery Right A.v ④ . RA pulmonary vein ⑥ lG - L # #Tricuspid P R Blood coming from the body , enter the heart through the vena cava into the right atrium & The right atrium will contract, pressure of blood in right atrium increase. Atrioventricular valve( tricuspid) open. iha : Blood is forced from right atrium into the right ventricle. 6 Dr .N ⑤ Right ventricle contract, right atrium relax, and pressure of blood in ventricle increase, (volume of Atrioventricular valve will close to prevent back flow of blood.,semilunar valve open ⑦ Blood is forced out of the heart through pulmonary artery to lungs (left) . lungs vein The left atrium will contract, pressure of blood in left atrium increase. Atrioventricular valve( bicuspid) open. Id Bicuspid 1. U . atrium pulmonary s decreased Blood coming from the lungd , enter the heart through the pulmonary vein, into the left to I. A ventricle To > Aorta Blood is forced from left atrium into the left ventricle. ' ( semilunar Vale . . ↳ to body . Left ventricle contract, left atrium relax, and pressure of blood in ventricle increase, Atrioventricular valve will close to prevent back flow of blood.,semilunar valve open Blood is forced out of the heart through aorta to body. 26/11 Dr .N iha lG ab r Animal transport part 2 Dr. Nihal Gabr Double circulatory system Heart Systemic and → Aorta pulmonary Heart circulation Pulmonary Body → - Pulmonary of double Heart lungs Heart - pulmonary vein . . lG Meaning . venaCava artery • circulation ab r Systemic circulatory system} Advantage II.To E- prevent Mixing blood of oxygenated Dr .N • iha Blood enters the heart twice in one complete circulation deoxygenated and ↳ maintain sleep concentration gradient For gas exchange 21 To pump blood under - high pressure to body Lower pressure to → lungs 2 diff pressures longer distance → to avoid . damage of lungs . DoubkCirculaHonJn mm → Blood enter the heart twice in one circulation Heart → lungs → Heart Body → Heart D. artery Heart → Aorta meee the iha Aduantaaesfm-twoaifa.me ptossuuemrbwnoigdnisndsesuetonoay ' longer energy demand of living metabolic - 2) blood - ( lungs to avoid → steep . gradient gases . → Csystemic circulation) of lungs high damage rate To prevent mixing of oxygenated and deoxygenated to conc Maintain with (Pulmonary Circulation) . distance b) lower pressure to organisms venaCava Dr .N '' → Ruein lG . ab r • ' . C) Single circulation Like in fish Disadvantages omg 1. Rapid fall in velocity and pressure of blood. 2. Pressure too low for efficient kidney function. iha lG - ab r In sufficient / slower supply of oxygen and nutrients Dr .N * singkcirculataysyslemgmm.BE loud enter the heart circuit inone Disadu-ST.is Rapid once fall in velocity and with oxygen and nutrients pressure → systole → is . too low For kidney Dr .N Function Diastole lG 3) body iha cells ab r pressure of blood 2) insufficient supply to Relay contract Remembering fgdtgpESBG.gg# has thicker wall than right ventricle to pump blood under higher pressure For lonuedistance * Cardiac cycle One heartbeat . . Diastole systole → relaxation Contraction ab r (0.8 Sec) o.US OIS o - ZS venhicukrsystokwhh-tn.am . Diastolezm AhiaesystoIe3mm lG → ventricle Semilunar value . contract relax relax open open Dr .N Atrioventricular value iha relax Close Filing of theheart relax contract close topreuentbacrftowol Blood close into . open ensuring emptying of the blood 'm atria . empty,nyd ventricles thehecrt . o Blood Forced outolhecnttobudyl . - Cardisc ac cycle or O - do one heart ab r beat G. Used relax Atrium A. uvula semilunar . . contract relax relax contract Open open close to Close close relax . Analysts Dr .N ventricle oenhicularsystok.fm mm iha Diastok3m G. 3Rd Cossey lG co .8sec) Filing of prevent backflow of blood . The ensuring emptying the heart ofatiumihtooenhick . - to atria . open to allow blood flow out of the heart to to push blood out of heat .com.ar#estgrmsane..es supplying heart muscle and glucose For respiration → walls - + narrower elastic obesity highFat intake high salt intake . atherosclerosis lack of . Dr .N iha - stiff Inch smoking lG ✓ Risk Factors . ab r CHD with OXYGEN exercise stress . Treatment ② - At risk → avoid excess avoid Drugs ② Taking lifestyle Improve their Stop smoking → , Fat and salt intake , stress, exercise . → ab r Statins: lower blood cholesterol level Anti platelets: aspirin reduce risk of blood clotting. ③ surgery - lG Antihypertensives: lower the blood pressure. → iha ← Blocked Dr .N Narrowedartery Angioplasty artery ↳Lent . 1 Insert a cable with non inflated balloon and stent in . Narrowed artery. 2 Inflate the balloon with water...press on walls of the . artery to wide open. - 3 Deflate the balloon and can leave a stent to hold on the . walls of artery. bypass the blocked area teatment3m→ I At risk . Improve → his Stating Taking drugs 2. → → life style exercising , → reduce Fat intake lower blood Cholesterol level . ab r of reduce Antipketektbmh aspirinclotting ANHhyperlensiueswmme.to blood pressure risk Angioplasty narrowed 1) insert 2) . arteries cable with and stent → iha a) Surgery c##×× Dr .N 3. lG → . we b) . Bypass → non - inflated balloon into the narrowed artery then in flat balloon with water press on the walls of artery to keep them open 3) Deflate balloon and can leave the stent to hold walls artery . of to bypass the blocked area . 29/11 Animal transport part 3 Dr .N iha lG ab r Pacemaker and blood vessels adaptation Dr.Nihal Gabr Heart muscle jm Involuntary muscle With no need to receive electrical impulses from the brain to keep contracting Pace maker: is a bundle of nerves found in the right atrium 1. Regulate rate of heart beats according to body demands. 2. Ensure atria contract before ventricles for emptying atria into ventricles ab r What if pacemaker stops: 1. Use artifical pacemaker replaced in person’s heart. Old: regular heart beats. lG New : can sense changes in breathing , movement and body temp so can adjust reate of heart beats. mime Dr .N iha How to monitor the activity of heart in hospitals: → Heart sound worm Dr .N iha lG ab r Measuring heart rate /pulse rate Emmy CK . 4 3/12 Dr .N iha lG ab r Blood vessels , blood components and lymphatic system Dr.Nihal Gabr tmrw Structure of blood vessels: ( IL → - thin .de/gego7yIgeInwjal sheny*enwawofauenres Arteries bi smooth muscles - mhg.faneiemaaaaaanf.am?n-neai.%cFbres Flow . under pressure . from the blood . lG Carry . Stretch recoil away heart under high pressure all arteries Cary oxygenated blood except pulmonary artery - E - AI R Blood flow . Dr .N Q - Thinner wall . → → 12hPa Tty * semilunar values → flow no . 7- sketch (expand) 6hPa recoil ( narrower) . flowing . resistance under low pressure preventing back flow of Tunaimsmtanensnore:* .ca#a.biggabpagssiun7Iood all veins carry deoxygenated blood except For Pulmonary vein . pressure - under low pressure offer Charrower) high under . as blood is wide lumen → to blood ( expand) to maintain blood flow . (2) being . high > Trichroism bursting tfoad.tyfetneugygnyepoew.b.io - iha • - from od transported . ab r pulmonary artery in heart prevent it Contract Cuasoconshiction) and relax Coasodilutron) → blood to maintain and → Next slide . EE÷hj÷÷ veins have blood → so blood has already lost its pressure + . wide lumen Veins are found embedded between lG ab r How blood flows in veins? In addition to presence of semilunar muscles......when muscles contract ......squeeze iha valves prevent back flow of blood. on blood in veins .....push blood up in veins Capillary's Function exchangeofof substances Dr .N (3) → By Diffusion reabsorption of Adaptors wall is gases Cosas exchange) . useful substances into 22 pores 8in their walls to allow small molecules 4 lumen almost Same size as that of RBC BBC can move to allow efficient → slowly so gas exchange → Faster . to reach to every - cell . diffusion filtration of From blood large number of branching capillaries to provide large surface area to allow blood 3 blood ex glucose thin wall one cell thick I For Shorter diffusion distance BBC between blood and cells lakeoli ~ a - o I Arterials • Allow exchange of substances Carry blood away from the between blood and cells/alveoli heart under high pressure. Transport/ carry blood to the heart under low pressure All veins carry deoxygenated ab r All carry oxygenated blood blood except for pulmonary except for pulmonary artery. lG vein 1. Wall is one cell thick ...shorter withstand high pressure diffusion distance. 1. Collagen to protect the walls from 2. They have pores to allow the 1.Thin outer wall and wide iha Have thick outer wall.....to lumen to offer no resistance to (vasoconstriction) and relax 3. Lumen almost same size as that muscles to squeeze on blood- (vasodilation)...changing volume of of RBCs, so they can move slowly blood transported to different body to allow efficient gas exchange . parts /organs. 4. Large number of branching bursting due to high pressure. filtration of small molecules from 2. Smooth muscles which contract blood. Dr .N a) . 3. Elastic fibres that stretch capillaries to provide large surface (expand) and recoil ( narrower) to area to reach to all body cells. maintain blood flow under high pressure b) narrow lumen . No values [except Parley 8 Aorta) . blood flow. 2. They are embedded between pushing it up towards the heart. 3. Semilunar valve to prevent back flow of blood. Blood omg omg Plasma 55%. 45% blood cells ← . RBCsjmwB.GS ab r n in topic Urea, lactic acid, carbondioxide hormones , ' lG b) Plasma proteins : fibrinogen , some Enzymes, antibodies. iha water 10% a) Dissolved substance Glucose, amino acids, vitamins V Dr .N 90% prig cells needed inidmmunity Erclottiny Platelets when they touch the damaged tissue......they become ① activated .....becoming more sticky....and mum ② some break and release thrombin enzyme. elk mum EVI catalyse the conversionof Soluble into Fibrinogen in - Soluble hr-br.is mm C.plasma protein Formed in liver) I . . Forming which - rmaclot which will then preventing entry of pathogen and dy out and Form Scab ← blood lose . . ' a mesh tap blood cells Bloodworm IEEE.BY#eietsPEYFYoutTssueTuidhSt - + Plasma proteins . through pores plasma + some typeset WBC, . but § allow of BBG ,no platelets no plasma proteins substances between blood and cells no . . Wp ab r L exchange - Og o O 0 & lG Tissue Fluid .ch cop) - I Artery B D Dr .N Bueso e iha g Carrying blood under high pressure away from the heart. To nyeotuimo.is Lymph . capillary by osmosis - y 2. Blood plasma filter out under high pressure through capillary pores (.... except for RBCs, platelets and plasma proteins ( as they are large).......forming tissue fluid.........which is an immmediate environment around every cell to allow exchange of substances between blood and cells. example. Glucose diffuse from blood to cell across tissue fluid) through capillary pores . 3 Tissue fluid return at the other end of = E. vein . °④ Lymphvessel Drainexcess tissue Fluid to juinlympnutc system . TssueAuidwm .BE/oodjm-sPkesmce+BBCs- Platelets + * WBG pores lG " iha signpost Tissue fluid .ro exchange of substances between bloodand . proteins Cells Young . . vein . low pressure . , lymph B. Dr .N Carrying blood under high pressure ↳ allow ⑨wp-containpw.mu ( h.w.pl O Artery RBCs , platelets and no plasma proteins ab r o away from the heart. no . ° . but no through capillary O high pressure - plasma Plasmaproteins Blood plasma , WBG Filtration of Blood . 2. Blood plasma filter out under high pressure through 3. Tissue fluid return at the other end of capillary by ↳ osmosis capillary pores ( example. Glucose diffuse from blood to cell across tissue fluid) through capillary pores.... except for RBCs, platelets and plasma proteins ( as they are large).......forming tissue fluid.........which is an immmediate environment around every cell to allow exchange of substances between blood and cells. mm vessel Imf * Tissue fluid End → How tissuefluid is Formed 11.immediate environment around every cell ( tissuefluid) . 2 Formed due to high pressure of blood coming in arteries away from the heart. . 3 Where blood plasma will be filtered out through capillary pores ( without RBCs, platelets , plasma . impf → ab r proteins). Allows exchange of substances between blood in capillaries and cells Example( diffusion of amino acid from blood in capillaries into the cells across tissue fluid,.....urea lG from cells to the blood in capillaries across tissue fluid) -# How tissue fluid returns at the other end of capillary ( nearer to veins)? By osmosis. Dr .N Importance of lymph vessels: Enmity * I \ iha * lymph vessel T # lyfmmsymphatcsystem.SI lymph nudes . Drain excess tissue fluid to be transported to the lymphatic system to rejoin the circulation thus preventing oedema to * tyaphno@roducefiaueusurroundceustopaentedema.T Fathi 2. Drain 3. Transport • ° ° w Bcs Transport Fatty 6. ? lymphatic sy excess tissue . ileum ( lacteal) → fluid acid, from the . 1. contain Team.FI:5?::::j,:nmY:inesT - . I. Foreign substances . insoluble in blood so it turns it into soluble Form . • • Blooding Timpani - Plasma-112134 . - Plasma WBC . lympts.mg Plasma + WBC . WBC, platelets Found in capillaries • Immediate ab r • . lymph vessels . environment around by high pressure ol Blood causing hitting of plasma out through Capillary . - . Formed Drainage of . iha . lG cells excess Dr .N → pores • Transport molecules tube exchanged with cells • tissue fluid vessels medium Er exchange - cells ① Pass . nodes . join lymphatic of substances between ① system Blood and lymph into . by → lymphocytes lymph release → Antibodies clean blood . Blood es Tissue fluid es Plasma + RBCs + Plasma + WBCs WBCs + platelets Lymph es Plasma + WBCs + plasma proteins ab r Immediate environmrnt In lymph vessels around cekls lG Found in blood capillaries Drainage of excess plasma filter out through lymph vessels Formed by high blood pressure iha coming from arteries, then tissue fluid into Transport substances to be exchanged with cells Dr .N capillary pores Allow exchange of substances between blood in capillaries and cells. Join the lymphatic system ...to pass by Lymphnodes thatproduce lymphocytes that release antibodies to clean the lymph from any foreign substances and to kill bacteria Rokoflympnwhicsyslemgmms.IO nodes → For the production of lymphocytes lymph Contain needed antibodies produce ② Drain excess lG edema . → ab r to → tissue ⑥Transport lacteal Dr .N through iha ③Transport fatty acids WBC, . ⑤ Return tissue fluid back to blood so they Soluble . b) - . fluid, preventing From villi in ileum are water insoluble need to be turned into water circulation betting Joining Fatty acid, through walls pathogens → fatty acids a) kill are large al capillaries . so cant . diffuse o reduce risk - of plague Formation on wall , d- arteries . o.Expkemhowlymphmaesinlympnoessels7.mn lymph vessel Lymph) nearby muscles → Lymph → semilunar value → prevent back flow lG of Lymph move squeeze on Forward → ab r 1- contract . iha . Dr .N I × , = ' Contract - y relax Biology IGCSE 0610 Page 7 October/November2010 Syllabus-0610 TRANSPORT IN HUMANS Paper 31 DrDr .N. N ihaih l Gal abGa r br 9 Paper 3 Dr.Nihal Gabr 267 Paper 3 TRANSPORT IN HUMANS DrDr .N. N ihaih l Gal abGa r br Biology IGCSE 0610 Dr.Nihal Gabr 268 Biology IGCSE 0610 17 Page 4 Paper 3 October/November 2013 TRANSPORT IN HUMANS Syllabus-0610 Paper 33 Page 7 October/November 2014 Dr 18 Dr. N .N ih ihaal l GG ababr r 1- Dr.Nihal Gabr 280 Syllabus-0610 Paper 32 Paper 3 TRANSPORT IN HUMANS DrDr .N. N ihaih l Gal abGa r br Biology IGCSE 0610 Dr.Nihal Gabr 281 5 2 (a) Fig. 2.1 shows the transfer of materials between blood and tissues. lymphatic vessel fluid A fluid B arteriole venule Key: flow of blood transfer of materials (i) Complete Table 2.1 by: • • lG ab r Fig. 2.1 stating the names of the fluids writing yes if the fluid contains red blood cells or no if the fluid does not contain red blood cells. iha Table 2.1 letter on Fig. 2.1 lymph Dr .N A name of the fluid B (ii) tissue fluid contains red blood cells no no [2] State the name of the process by which oxygen is transferred from fluid B to the cells. Diffusion ..................................................................................................................................... [1] (iii) . Explain why cells need oxygen. Respiration For aerobic ........................................................................................................................................... to ........................................................................................................................................... release energy ( protein synthesis) For cell metabolic reaction ........................................................................................................................................... . ........................................................................................................................................... ..................................................................................................................................... [2] plasma Fibrinogen proteins → © UCLES 2020 enzymes antibodies and some hormones (insulin 0610/42/F/M/20 [Turn over glucagon ) . . 6 (b) Describe the functions of arterioles in the skin. - by helping maintaining a role in homeostasis ................................................................................................................................................... plays body temp Constant ................................................................................................................................................... . relaxation By of smooth contraction and ................................................................................................................................................... . vasoconstriction muscles in a Knoles → ................................................................................................................................................... Causing - vasodilation of changing volume → thus or ................................................................................................................................................... flowing surface blood in near skin ................................................................................................................................................... capillaries ............................................................................................................................................. [3] (c) Describe the functions of lymph nodes in the lymphatic system. lymphocytes produce AB Contain ................................................................................................................................................... → kill . lG ab r ' pathogen ................................................................................................................................................... Cleaning . lymph before returning the ................................................................................................................................................... . Circulation it back to blood ................................................................................................................................................... . . ............................................................................................................................................. [2] (i) iha (d) Lacteals are part of the lymphatic system. State where in the body lacteals are found. Dr .N Villi ..................................................................................................................................... [1] (ii) Describe the role of lacteals. = Fatty acids absorb ( Transport ........................................................................................................................................... . ........................................................................................................................................... ..................................................................................................................................... [1] [Total: 12] © UCLES 2020 0610/42/F/M/20 . lG iha Dr .N ¥ # ab r ¥¥¥*¥ Checklist 1. Heart label 2. Importance of having a double circulatory system. 3. Disadvantages of having a single circulatory system. pressures - 6. Risk factors for CHD - Atrial - cent preventing Mixing of oxy and deoxy blood supply . . mm a Muscle with oxygen . artery Dr .N Narrowed artery V.Blocked . iha - velocity lG ( drugs : statins, anti hypertensives, anti platelets ) ( surgery ; angioplasty, by pass ) low heart - mm . ow pressure . systole systole different . . Diastole 5. Coronary arteries function 7. Treatment under 2 ab r 4. Cardiac cycle { - Pump blood 8. Cardiac muscle ; involuntary with no need to receive nerve impulses to contract . 9. Pacemaker ( found right atrium) its a bundle of nerves send electrical impulses across walls of atria / heart muscle A) .regulate rate of heart beats according to the body activity. B) Ensure that the atria contract before the ventricles . 10. Replacement by artificial pace maker. 11. Heart rate= pulse rate (bpm) 12. Pulse in arteries ( how to measure) 13. How to hear heart sound ( stethoscope lub bud sound ) 14. How to monitor heart beats at a hospital (ECG) 15. Structure and function of artery , vein and capillary 16. Role of tissue fluid ab r 17.role of lymphatic system 18, why fatty acids are transported through lacteal into lymphatic system Dr .N iha lG 19. How lymph moves in lymph vessels.