CH 8 BIOLOGY CLASS 12 LIFE CYCLE OF PLASMODIUM VIVAX. The name malaria is given by Macculoch. Believe that it is caused by the foul air of the marshy localities. Laveran ,a French medical officer discovered the malaria parasite in the blood of a malarial patient.SIR RONALD ROSS of the Indian medical service find information information about mosquito malaria relationship. LIFE HISTORY….. Plasmodium completed its life cycle in two phases and to host asexual phase in human host and sexual phase in female anopheles mosquito host . THE LIFE CYCLE OF PLASMODIUM SUBDIVIDED INTO THREE PHASES….. 1. SCHIZOGONY …. A phase Of growth and a sexual multiplication are occuring in man…… It further consists of of two phases ….. A .EXOERYTHROXYTIC SCHIZOGONY …. The parasite find their way into the blood of a healthy man along with the salivary secretion of infected mosquito. At this stage the parasite are called sporozoites. It is only 0.002 mm long and contain a nucleusi in the broad middle part. Infected liver cells and become sphericals and are called cryptozoites. 8 forms a rounded shape schizont which divides by repeated mitosis and forms cryptomerozoites . When the effected another liver cells known as meta cryptozoites. These are of two types one is micro micrometa cryptozoites.and macrometacryptozoites. It takes about 8 to 10 days. B. ERYTHROCYTIC SCHIZOGONY …It is when the parasites enter the RBC it forms round shape which is called trophozoites. It pushes nucleus to the the site and forms signet ring stage. After further growth it forms amoeboid stage. With the help of pseudopodia that opposite digest the cytoplasm of RBC.After 36 hours ,the trophozoites that becomes mature. It is ready for multiple fission and is called the schizont. Its nucleus divide to form 24 nucleus now it is called schizozoites. It arrange themselves round the residential site of class like the petals of rose flower. This is stage is called the rosette stage . After 48 hours the RBC becomes weak and ruptures and and patient feel shivering. 2 .GAMOGONY .,…During RBC infection those parasites not enter the RBC forms rounded bodies. Which lack a vacuole and grow more slowly. These forms sexual forms and called gametocytes. These are are of two types microgametocytes (male)and macrogametocytes (female ). These are sucked by mosquito for sexual reproduction. Which are not sucked destroy in the blood.. In the stomach of mosquito in forms zygote. Result of sexual reproduction. Zygote is rounded and motionless. It becomes elongated and worm like ookinete . Which rupture the wall of stomach. And forms hard cyst wall around the zygote . called oocyst. @@@@@@@@@@@@@@@CONTINUE….,………