UKMLA Study Guide Table of Contents Welcome to AMBOSS! . . . . . . . . . . . . . . . . . . . . . . . . Acute and emergency . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cardiovascular . . . . . . . . . . 3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 7 . . . 9 . . . . . . . . . . . . . . 12 . Child health . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Clinical haematology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Clinical imaging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 . Ear, nose and throat . . . . Endocrine and metabolic . . . . . . . . . . . . Infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Medicine of older adult . . . . . . . . . . . . . . . . . . . . . . . . . . Musculoskeletal . Neurosciences . . . . . . . . . . . . . . . . . . Palliative and end of life care . Renal and urology . Respiratory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 . . 42 . .44 . 46 . . 38 . . . . . 36 . . . 34 . . . 32 . . . . . 30 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Obstetrics and gynaecology . Ophthalmology . . . 28 . . . 25 . . . . 23 . . . 21 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mental health . . . . . General practice and primary healthcare . Gastrointestinal including liver . . . . 48 Sexual health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 . . Areas of professional knowledge . . . . . . . . . . . . . . . . . . . . . . . 55 . . Clinical and professional capabilities . . . . . . . . . . . . . . . . . . . . . . . 55 All areas of clinical practice . . . . . . . . . . . . . . . . . . . . . . . 56 . . . Welcome to AMBOSS! Created by a team of dedicated physicians, AMBOSS is an interactive library of 20,000+ medical topics interlinked with a Question Bank with over 5,000 clinical case-based questions. With all the necessary resources in one place, AMBOSS delivers up-to-date medical knowledge to students, physicians, and faculty around the world. We developed the United Kingdom Medical Licensing Assessment (UKMLA) Study Guide to serve as a comprehensive checklist of topics you should know. The guide is based on the General Medical Council's content outline and its topics are linked to corresponding articles on the AMBOSS platform. Click on each topic to access the library articles, from which you can navigate seamlessly into the Question Bank at any time. Please note: to visit the articles, you will need to have an AMBOSS account with access. If you already have an account, you can log in here. If you’re new to AMBOSS, you can register for a free five-day trial here. Click here to open library articles Click here to answer multiple choice questions We recommend that all candidates also check the latest guidance provided by the General Medical Council regarding this assessment. With AMBOSS, you’ll be able to study for your exams online, but you can also access our study resources offline by downloading the AMBOSS Knowledge Library and Question Bank applications for Android and iOS Finally, the AMBOSS team is here to support you. If you have questions, suggestions or comments, please do not hesitate to contact us at hello@amboss.com. Happy studying! > INDEX | 3 Acute and emergency > INDEX | 4 Acute and emergency Topic AMBOSS Article Acid-base abnormality Acid-base disorders Acute bronchitis Acute bronchitis Acute coronary syndromes Acute coronary syndrome Acute kidney injury Acute kidney injury Allergic disorder Hypersensitivity reactions Anaphylaxis Anaphylaxis Aortic aneurysm Abdominal aortic aneurysm Thoracic aortic aneurysm Arrhythmias Overview of cardiac arrhythmias Cardiac arrest Cardiac arrest and cardiopulmonary resuscitation Compartment syndrome Compartment syndrome Deep vein thrombosis Deep vein thrombosis Dehydration Dehydration and hypovolemia Diabetic ketoacidosis Hyperglycemic crises Drug overdose Substance-related and addictive disorders Opioid overdose Non-opioid analgesics Sedative-hypnotic drugs Ectopic pregnancy Ectopic pregnancy Hyperosmolar hyperglycaemic state Hyperglycemic crises Hyperthermia and hypothermia Heatstroke Hypothermia and frostbite Myocardial infarction Myocardial infarction > INDEX | 5 Acute and emergency Topic AMBOSS Article Necrotising fasciitis Skin and soft tissue infections Non-accidental injury Child maltreatment Pneumothorax Pneumothorax Pulmonary embolism Pulmonary embolism Raised intracranial pressure Elevated intracranial pressure and brain herniation Respiratory arrest Respiratory failure and arrest Respiratory failure Respiratory failure and arrest Self-harm Suicide Sepsis Sepsis Spinal cord compression Degenerative disk disease Spinal fracture Vertebral fractures Stroke Overview of stroke Subarachnoid haemorrhage Subarachnoid hemorrhage Subdural haemorrhage Subdural hematoma Substance use disorder Substance-related and addictive disorders Unstable angina Acute coronary syndrome > INDEX | 6 Cancer > INDEX | 7 Cancer Topic AMBOSS Article Bladder cancer Urinary tract cancer Brain metastases Brain tumors Breast cancer Breast cancer Cervical cancer Cervical cancer Colorectal tumours Colorectal cancer Endometrial cancer Endometrial cancer Gastric cancer Gastric cancer Hypercalcaemia of malignancy Hypercalcemia Leukaemia Acute leukemia Chronic lymphocytic leukemia Lung cancer Lung cancer Lymphoma Hodgkin lymphoma Non-Hodgkin lymphomas Malignant melanoma Melanoma Multiple myeloma Multiple myeloma Oesophageal cancer Esophageal cancer Ovarian cancer Ovarian tumors Pancreatic cancer Pancreatic cancer Pathological fracture General principles of fractures Prostate cancer Prostate cancer Testicular cancer Testicular tumors > INDEX | 8 Cardiovascular > INDEX | 9 Cardiovascular Topic AMBOSS Article Aneurysms, ischaemic limb and occlusions Abdominal aortic aneurysm Thoracic aortic aneurysm Aneurysm Acute limb ischemia Peripheral arterial disease Aortic dissection Aortic dissection Aortic valve disease Aortic valve stenosis Aortic regurgitation Arterial thrombosis Hypercoagulable states Arterial ulcers Peripheral arterial disease Cardiac failure Congestive heart failure Essential or secondary hypertension Hypertension Gangrene Cellular changes and adaptive responses Wound treatment Infective endocarditis Infective endocarditis Intestinal ischaemia Intestinal ischemia Ischaemic heart disease Coronary artery disease Mitral valve disease Mitral valve stenosis Mitral regurgitation Mitral valve prolapse Myocarditis Myocarditis Pericardial disease Pericarditis Pericardial effusion and cardiac tamponade Peripheral vascular disease Peripheral arterial disease > INDEX | 10 Cardiovascular Topic AMBOSS Article Pulmonary hypertension Pulmonary hypertension and cor pulmonale Right heart valve disease Valvular heart diseases Vasovagal syncope Syncope Venous ulcers Chronic venous disease > INDEX | 11 Child health > INDEX | 12 Child health Topic AMBOSS Article Appendicitis Acute appendicitis Asthma Asthma Atopic dermatitis and eczema Atopic dermatitis Attention deficit hyperactivity disorder Attention deficit hyperactivity disorder Autism spectrum disorder Autism spectrum disorder Biliary atresia Congenital visceral malformations Bronchiolitis Bronchiolitis Candidiasis Candidiasis Cerebral palsy and hypoxic-ischaemic encephalopathy Cerebral palsy Coeliac disease Celiac disease Croup Croup Cystic fibrosis Cystic fibrosis Developmental delay Neurodevelopmental disorders Down's syndrome Down syndrome Eating disorders Eating disorders Epididymitis and orchitis Epididymitis Orchitis Epiglottitis Epiglottitis Febrile convulsion Febrile seizures Gastro-oesophageal reflux disease Gastroesophageal reflux disease Henoch-Schonlein purpura IgA vasculitis Human papilloma virus infection Human papillomavirus infection Idiopathic arthritis Juvenile idiopathic arthritis Impetigo Impetigo > INDEX | 13 Child health Topic AMBOSS Article Intussusception Intussusception Kawasaki disease Kawasaki disease Malaria Malaria Malnutrition Protein-energy malnutrition Vitamins Measles Measles Migraine Migraine Mumps Mumps Muscular dystrophies Progressive muscular dystrophies Otitis media Acute otitis media Pyloric stenosis Hypertrophic pyloric stenosis Rubella Rubella Viral exanthema Measles Scarlet fever Rubella Fifth disease Roseola infantum Viral gastroenteritis Infectious gastroenteritis > INDEX | 14 Clinical haematology > INDEX | 15 Clinical haematology Topic AMBOSS Article Anaemia Anemia Disseminated intravascular coagulation Disseminated intravascular coagulation Haemochromatosis Hemochromatosis Haemoglobinopathies Thalassemia Sickle cell disease Haemophilia Hemophilia Hyposplenism/splenectomy Asplenia Myeloproliferative disorders Myeloproliferative neoplasms Pancytopenia Laboratory medicine Patient on anti-platelet therapy Antiplatelet agents Patient on anti-coagulant therapy Oral anticoagulants Parenteral anticoagulation Polycythaemia Polycythemia vera Sickle cell disease Sickle cell disease Transfusion reactions Transfusion reactions > INDEX | 16 Clinical imaging > INDEX | 17 Clinical imaging Topic AMBOSS Article Intestinal obstruction and ileus Bowel obstruction Paralytic ileus Lower limb fractures Hip fractures Pelvic fracture Femoral shaft fracture Tibial fracture Ankle fracture Talus fractures Lower limb soft tissue injury Insertional tendinopathy Wound treatment Upper limb fractures Humerus fracture Clavicle fracture Scaphoid fracture Metacarpal fractures Upper limb soft tissue injury Soft tissue lesions of the shoulder Shoulder dislocation Insertional tendinopathy Wound treatment > INDEX | 18 Dermatology > INDEX | 19 Dermatology Topic AMBOSS Article Acne vulgaris Acne vulgaris Basal cell carcinoma Basal cell carcinoma Cellulitis Skin and soft tissue infections Contact dermatitis Allergic contact dermatitis Cutaneous fungal infection General mycology Cutaneous warts Benign skin lesions Folliculitis Skin and soft tissue infections Head lice Lice infestation Psoriasis Psoriasis Scabies Scabies Squamous cell carcinoma Cutaneous squamous cell carcinoma Urticaria Hypersensitivity reactions > INDEX | 20 Ear, nose and throat > INDEX | 21 Ear, nose and throat Topic AMBOSS Article Acoustic neuroma Acoustic neuroma Benign paroxysmal positional vertigo Benign paroxysmal positional vertigo Epistaxis Epistaxis Infectious mononucleosis Infectious mononucleosis Ménière's disease Meniere disease Obstructive sleep apnoea Obstructive sleep apnea Otitis externa Otitis externa Rhinosinusitis Sinusitis Tonsillitis Acute tonsillitis and pharyngitis > INDEX | 22 Endocrine and metabolic > INDEX | 23 Endocrine and metabolic Topic AMBOSS Article Addison's disease Adrenal insufficiency Cushing’s syndrome Cushing syndrome Diabetes in pregnancy (gestational and pre-existing) Diabetes mellitus in pregnancy Diabetes insipidus Diabetes insipidus Diabetes mellitus type 1 and 2 Diabetes mellitus Diabetic nephropathy Complications of diabetes mellitus Diabetic neuropathy Complications of diabetes mellitus Hyperlipidemia Lipid disorders Hyperparathyroidism Hyperparathyroidism Hypoglycaemia Hypoglycemia Hypoparathyroidism Hypoparathyroidism Hypothyroidism Hypothyroidism Osteomalacia Osteomalacia and rickets Pituitary tumours Pituitary adenoma Thyroid eye disease Orbital disorders Thyroid nodules Thyroid nodules Thyrotoxicosis Hyperthyroidism and thyrotoxicosis > INDEX | 24 Gastrointestinal including liver > INDEX | 25 Gastrointestinal including liver Topic AMBOSS Article Acute cholangitis Acute cholangitis Acute pancreatitis Acute pancreatitis Alcoholic hepatitis Alcoholic hepatitis Ascites Ascites Cholecystitis Acute cholecystitis Cirrhosis Cirrhosis Constipation Constipation Diverticular disease Diverticulitis Diverticulosis Gallstones and biliary colic Cholelithiasis Haemorrhoids Hemorrhoids Hepatitis Hepatitis A Hepatitis B Hepatitis C Hepatitis D Hepatitis E Hiatus hernia Hiatal hernia Infectious colitis Infectious gastroenteritis Inflammatory bowel disease Crohn disease Ulcerative colitis Irritable bowel syndrome Irritable bowel syndrome Liver failure Acute liver failure Malabsorption Malabsorption > INDEX | 26 Gastrointestinal including liver Topic AMBOSS Article Mesenteric adenitis Lymphadenopathy Infectious gastroenteritis in children Necrotising enterocolitis Necrotizing enterocolitis Peptic ulcer disease and gastritis Peptic ulcer disease Gastritis Peritonitis Spontaneous bacterial peritonitis Vitamin B12 and/or folate deficiency Vitamin B12 deficiency Folate deficiency > INDEX | 27 General practice and primary healthcare > INDEX | 28 General practice and primary healthcare Topic AMBOSS Article Acute stress reaction Trauma- and stressor-related disorders Atrophic vaginitis Vulvovaginitis Bacterial vaginosis Vulvovaginitis Bell's palsy Facial nerve palsy Benign eyelid disorders Inflammation of the eyelids Bursitis Collection of orthopedic conditions Chronic fatigue syndrome Chronic fatigue syndrome Depression Major depressive disorder Disease prevention/screening Interpreting medical evidence Fibromyalgia Fibromyalgia Lyme disease Lyme disease Menopause Menopause Obesity Obesity and metabolic syndrome Tension headache Tension-type headache Trichomonas vaginalis Vulvovaginitis Varicella zoster Herpes virus infections Whooping cough Pertussis > INDEX | 29 Infection > INDEX | 30 Infection Topic AMBOSS Article Brain abscess Brain abscess Covid-19 COVID-19 (coronavirus disease 2019) Encephalitis Encephalitis Herpes simplex virus Herpes simplex virus infections Hospital acquired infections Hospital-acquired infections Human immunodeficiency virus Human immunodeficiency virus infection Infectious diarrhoea Diarrhea Influenza Influenza Meningitis Meningitis Notifiable diseases Principles of medical law and ethics Septic arthritis Septic arthritis Surgical site infection Postoperative management Toxic shock syndrome Toxic shock syndrome Tuberculosis Tuberculosis Urinary tract infection Urinary tract infections Viral hepatitides Hepatitis A Hepatitis B Hepatitis C Hepatitis D Hepatitis E > INDEX | 31 Medicine of older adult > INDEX | 32 Medicine of older adult Topic AMBOSS Article Delirium Delirium Dementias Major neurocognitive disorder Osteoporosis Osteoporosis Parkinson's disease Parkinson disease Pressure sores Decubitus ulcers Urinary incontinence Urinary incontinence > INDEX | 33 Mental health > INDEX | 34 Mental health Topic AMBOSS Article Anxiety disorder: generalised Anxiety disorders Anxiety disorder: post-traumatic stress disorder Trauma- and stressor-related disorders Anxiety, phobias, OCD Anxiety disorders Obsessive-compulsive disorder Bipolar affective disorder Bipolar disorder Personality disorder Personality disorders Schizophrenia Schizophrenia Somatisation Somatic symptom and related disorders Wernicke's encephalopathy Wernicke encephalopathy and Korsakoff syndrome > INDEX | 35 Musculoskeletal > INDEX | 36 Musculoskeletal Topic AMBOSS Article Ankylosing spondylitis Ankylosing spondylitis Crystal arthropathy Gout and hyperuricemia Osteoarthritis Osteoarthritis Osteomyelitis Osteomyelitis Polymyalgia rheumatica Polymyalgia rheumatica Reactive arthritis Reactive arthritis Rheumatoid arthritis Rheumatoid arthritis Sarcoidosis Sarcoidosis Systemic lupus erythematosus Systemic lupus erythematosus > INDEX | 37 Neurosciences > INDEX | 38 Neurosciences Topic AMBOSS Article Epilepsy Seizures and epilepsy Essential tremor Tremor Extradural haemorrhage Epidural hematoma Motor neurone disease Neurological examination Spinal muscular atrophy Amyotrophic lateral sclerosis Multiple sclerosis Multiple sclerosis Myasthenia gravis Myasthenia gravis Peripheral nerve injuries/palsies Peripheral nerve injuries Radiculopathies Degenerative disk disease Spinal cord injury Complete spinal cord injury Incomplete spinal cord syndromes Transient ischaemic attacks Transient ischemic attack Trigeminal neuralgia Trigeminal neuralgia > INDEX | 39 Obstetrics and gynaecology > INDEX | 40 Obstetrics and gynaecology Topic AMBOSS Article Breast abscess/ mastitis Breast abscess Mastitis Cervical screening (HPV) Cervical cancer Cord prolapse Abnormal labor and delivery Endometriosis Endometriosis Fibroids Uterine leiomyoma Obesity and pregnancy Care of Women with Obesity in Pregnancy Pelvic inflammatory disease Pelvic inflammatory disease Placenta praevia Antepartum hemorrhage Placental abruption Antepartum hemorrhage Postpartum haemorrhage Postpartum hemorrhage Pre-eclampsia, gestational hypertension Hypertensive pregnancy disorders Termination of pregnancy Induced abortion Vasa praevia Antepartum hemorrhage VTE in pregnancy and puerperium Pulmonary embolism > INDEX | 41 Ophthalmology > INDEX | 42 Ophthalmology Topic AMBOSS Article Acute glaucoma Glaucoma Blepharitis Inflammation of the eyelids Cataracts Cataract Central retinal arterial occlusion Retinal vessel occlusion Chronic glaucoma Glaucoma Conjunctivitis Overview of conjunctivitis Diabetic eye disease Complications of diabetes mellitus Infective keratitis Keratitis Iritis Diseases of the uvea Macular degeneration Age-related macular degeneration Optic neuritis Disorders of the visual pathway Periorbital and orbital cellulitis Orbital disorders Retinal detachment Retinal detachment Scleritis Scleritis and episcleritis Uveitis Diseases of the uvea Visual field defects Disorders of the visual pathway > INDEX | 43 Palliative and end of life care > INDEX | 44 Palliative and end of life care Topic AMBOSS Article Metastatic disease General oncology Multi-organ dysfunction syndrome Sepsis > INDEX | 45 Renal and urology > INDEX | 46 Renal and urology Topic AMBOSS Article Benign prostatic hyperplasia Benign prostatic hyperplasia Bronchiectasis Bronchiectasis Chronic kidney disease Chronic kidney disease Nephrotic syndrome Nephrotic syndrome Urinary tract calculi Nephrolithiasis > INDEX | 47 Respiratory > INDEX | 48 Respiratory Topic AMBOSS Article Asbestos-related lung disease Asbestosis Asthma COPD overlap syndrome Asthma Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease Fibrotic lung disease Interstitial lung disease Lower respiratory tract infection Pneumonia Acute exacerbation of chronic obstructive pulmonary Bronchiectasis Acute bronchitis Occupational lung disease Silicosis Interstitial lung diseases Hypersensitivity pneumonitis Asbestosis Pneumonia Pneumonia Upper respiratory tract infection Common cold Sinusitis Bacterial tracheitis Epiglottitis Influenza Laryngitis > INDEX | 49 Sexual health > INDEX | 50 Sexual health Topic AMBOSS Article Chlamydia Chlamydia infections Gonorrhoea Gonorrhea Syphilis Syphilis > INDEX | 51 1. Surgery 2. All areas of clinical practice > INDEX | 52 1. Surgery Topic AMBOSS Article Anal fissure Anal fissures Breast cysts Breast cysts Fibroadenoma Fibroadenoma Gastrointestinal perforation Gastrointestinal perforation Hernias Abdominal hernias Obstructive sleep apnoea Obstructive sleep apnea Perianal abscesses and fistulae Anal abscess and fistula Testicular torsion Testicular torsion Varicose veins Chronic venous disease Volvulus Volvulus 2. All areas of clinical practice Topic AMBOSS Article Adverse drug effects Chapter link: Adverse effects and toxicities > INDEX | 53 1. Areas of professional knowledge 2. Clinical and professional capabilities > INDEX | 54 1. Areas of professional knowledge Topic AMBOSS Article Allergy and immunology Chapter link: Rheumatology and immunology Biomedical sciences Chapter link: Anatomy and histology Chapter link: Physiology Chapter link: Pathology Aging changes Clinical biochemistry Chapter link: Biochemistry Clinical pharmacology and therapeutics Chapter link: Pharmacology Pain management Genetics and genomics Chapter link: Genetics Histopathology General histology Pathology techniques Human factors and quality improvement Quality and safety Laboratory haematology Laboratory medicine Medical ethics and law Principles of medical law and ethics Microbiology Chapter link: Microbiology Infection prevention and control Psychological principles Chapter link: Psychology, ethics, and counseling Social and population health Chapter link: Public health Chapter link: Social sciences > INDEX | 55 2. Clinical and professional capabilities Topic AMBOSS Article Practical skills and procedures Practical skills and procedures - General Medical Council Practical skills and procedures > INDEX | 56