#separator:tab #html:true #tags column:3 Target of Penicillin?Cell wall Target of CarbapenemCell wall Target of Cephalosporin?Cell wall Target of Gylcopeptide?Cell wall "Example of&nbsp;<b><div><span style=""font-weight: 400;"">Carbapenem</span></div></b><br>""<b><span style=""font-weight: 400;"">Mero</span>penem</b>" Example of Penicllin"<b><div><span style=""font-weight: 400;"">Amoxi</span>cillin<span style=""font-weight: 400;"">&nbsp;</span></div><div><span style=""font-weight: 400;"">Flucloxa</span>cillin<span style=""font-weight: 400;""> (great for staph a skin infections)</span></div></b><br>" Target of Amoxi<b>cillin /&nbsp;</b>Flucloxacillin<br><b>&nbsp;&nbsp;</b><b><div><br></div></b><br>Cell wall Target of MeropenemCell wall Name of a Caphalosporin?"<b><div>cef<span style=""font-weight: 400;"">triaxone&nbsp;</span></div>cef<span style=""font-weight: 400;"">alexin</span></b><br>" "Target of&nbsp;<b><div>cef<span style=""font-weight: 400;"">triaxone&nbsp;</span></div>cef<span style=""font-weight: 400;"">alexin</span></b>"Cell wall Name of a Glycopeptide?"<b><div><span style=""font-weight: 400;"">Vancomycin</span></div><div><span style=""font-weight: 400;"">teicoplanin</span></div></b><br>" Target of Vancomycin<b>&nbsp;/</b>teicoplanin<b><br></b>Cell wall Side affects for penicllin?Allergies Side affect for amoxicillin?Allergies side effect for flucloxacillin?allergies<br> Key facts about Penicillin?"<b><ul><li><div><span style=""font-weight: 400;"">Penicillin G is destroyed by gastric acid to give IM or IV</span></div></li><li><div><span style=""font-weight: 400;"">Penicillin V can be given orally.&nbsp;</span></div></li><li><div><span style=""font-weight: 400;"">Beta lactamases can cause resistance, clavulanic acid can help combat this e.g. co-amoxiclav</span></div></li></ul></b>" Side effects of Carbapenem?"<b><ul><li><div><span style=""font-weight: 400;"">Dose related seizures</span></div></li><li><div><span style=""font-weight: 400;"">cross sensitization with penicillin (if they are allergic to penicillin don't give them this)</span></div></li></ul></b>" Side effects of Meropenem?"<b><ul><li><div><span style=""font-weight: 400;"">Dose related seizures</span></div></li><li><div><span style=""font-weight: 400;"">cross sensitization with penicillin (if they are allergic to penicillin don't give them this)</span></div></li></ul></b>" Side effects of Cephalosporin?"<b><ul><li><div><span style=""font-weight: 400;"">GI upset</span></div></li><li><div><span style=""font-weight: 400;"">Allergies</span></div></li><li><div><span style=""font-weight: 400;"">drug induced alcohol sensitivity</span></div></li></ul></b>" "Side effects of&nbsp;<b>cef<span style=""font-weight: 400;"">triaxone&nbsp;</span></b>?""<b><ul><li><div><span style=""font-weight: 400;"">GI upset</span></div></li><li><div><span style=""font-weight: 400;"">Allergies</span></div></li><li><div><span style=""font-weight: 400;"">drug induced alcohol sensitivity</span></div></li></ul></b>" "Side effects of&nbsp;<b>cef<span style=""font-weight: 400;"">alexin</span></b><b><span style=""font-weight: 400;"">e&nbsp;</span></b>?""<b><ul><li><div><span style=""font-weight: 400;"">GI upset</span></div></li><li><div><span style=""font-weight: 400;"">Allergies</span></div></li><li><div><span style=""font-weight: 400;"">drug induced alcohol sensitivity</span></div></li></ul></b>" Key facts about Cephalosporin?"<b><ul><li><div><span style=""font-weight: 400;"">Is able to cross blood brain barrier so can treat brain infections</span></div></li></ul></b>" Side effects for Gycopeptide?"<b><ul><li><div><span style=""font-weight: 400;"">Thrombophlebitis</span></div></li><li><div><span style=""font-weight: 400;"">ototoxicity</span></div></li></ul></b>" "Side effects for&nbsp;<b><span style=""font-weight: 400;"">Vancomycin</span></b>?""<b><ul><li><div><span style=""font-weight: 400;"">Thrombophlebitis</span></div></li><li><div><span style=""font-weight: 400;"">ototoxicity</span></div></li></ul></b>" "Side effects for&nbsp;<b><span style=""font-weight: 400;"">teicoplanin</span></b>?""<b><ul><li><div><span style=""font-weight: 400;"">Thrombophlebitis</span></div></li><li><div><span style=""font-weight: 400;"">ototoxicity</span></div></li></ul></b>" Key facts about Glycopeptides?"<b><ul><li><div><span style=""font-weight: 400;"">Vancomycin&nbsp; is the antibiotic of choice for MRSA.&nbsp;</span></div></li><li><div><span style=""font-weight: 400;"">Not absorbed by gut so must inject.</span></div></li></ul></b>" "Target for&nbsp;<b><span style=""font-weight: 400;"">Fluoroquinolones?&nbsp;</span></b>"DNA synthesis "Target for Cipro<span style=""font-weight: bold;"">flox</span>acin?<b><br></b>"DNA synthesis Side effects for Fluoroquinolones<b><br></b>"<b><ul><li><div><span style=""font-weight: 400;"">GI disturbance, is assoicated with C.Diff overgrowth</span></div></li></ul></b>" Side effects for cipro<b>flox</b>acin?"<b><ul><li><div><span style=""font-weight: 400;"">GI disturbance, is assoicated with C.Diff overgrowth</span></div></li></ul></b>" Key facts about Fluroquinolones?"<b><ul><li><div><span style=""font-weight: 400;"">Inhibits DNA gyrase and topoisomerase II</span></div></li></ul></b>" Target of Metronidazole?DNA synthesis Side effects of Metronidazole?No alcohol Key facts about MetronidazoleGood against anaerobic bacteria Name a type of fluoroquinolones?Ciprofloxacin What is the target for Sulfonamides?Folate synthesis What is the target for&nbsp;<b>Sulf</b>amethoxazole?Folate synthesis Name a type of sulfonamide?"<b>Sulf<span style=""font-weight: 400;"">amethoxazole</span></b>" "What are the side effects of&nbsp;<b>Sulf<span style=""font-weight: 400;"">amethoxazole</span></b>""<b><ul><li><div><span style=""font-weight: 400;"">Hepatitis</span></div></li><li><div><span style=""font-weight: 400;"">toxic epidermal necrolysis</span></div></li><li><div><span style=""font-weight: 400;"">anaphylaxis</span></div></li></ul></b>" What are the side effects of&nbsp;Sulfonamide?<b><br></b>"<b><ul><li><div><span style=""font-weight: 400;"">Hepatitis</span></div></li><li><div><span style=""font-weight: 400;"">toxic epidermal necrolysis</span></div></li><li><div><span style=""font-weight: 400;"">anaphylaxis</span></div></li><li><div><span style=""font-weight: 400;"">Hepatitis</span></div></li><li><div><span style=""font-weight: 400;"">toxic epidermal necrolysis</span></div></li><li><div><span style=""font-weight: 400;"">anaphylaxis</span></div></li></ul></b>" "What are the key facts of&nbsp;<b><span style=""font-weight: 400;"">Sulfonamides?</span></b>""<b><ul><li><div><span style=""font-weight: 400;"">Competes for dihydroorotate synthetase.&nbsp;</span></div></li><li><div><span style=""font-weight: 400;"">Give with trimethoprim as trimoxazole.&nbsp;</span></div></li><li><div><span style=""font-weight: 400;"">Particularly good against P.Jirovecii and T. gondii</span></div></li></ul></b>" What is the target for Trimethoprim?&nbsp;<b><br></b>Folate synthesis? What are the key facts for Trimethoprim?&nbsp;<b><br></b>"<b><ul><li><div><span style=""font-weight: 400;"">Competes for dihydrofolate reductase</span></div></li><li><div><span style=""font-weight: 400;"">used to treat UTIs</span></div></li></ul></b>" What is the target for Aminogycosides?Protein synthesis What is the target for Gentamicin?Protein synthesis What is the target for streptomcyin?Protein synthesis Name a type of Aminoglycoside?"<b><span style=""font-weight: 400;"">Gentamicin, streptomycin</span></b>" "Side effects of&nbsp;<b><span style=""font-weight: 400;"">Gentamicin</span></b>""<b><ul><li><div><span style=""font-weight: 400;"">Ototoxicity</span></div></li><li><div><span style=""font-weight: 400;"">nephrotoxic</span></div></li></ul></b>" "Side effects of&nbsp;<b><span style=""font-weight: 400;"">streptomycin?</span></b>""<b><ul><li><div><span style=""font-weight: 400;"">Ototoxicity</span></div></li><li><div><span style=""font-weight: 400;"">nephrotoxic</span></div></li></ul></b>" "Side effects of&nbsp;<b><span style=""font-weight: 400;"">Aminoglycosides</span></b><b><span style=""font-weight: 400;"">?</span></b>""<b><ul><li><div><span style=""font-weight: 400;"">Ototoxicity</span></div></li><li><div><span style=""font-weight: 400;"">nephrotoxic</span></div></li></ul></b>" Key facts for Aminoclycosides?"<b><ul><li><div><span style=""font-weight: 400;"">30S ribosome</span></div></li></ul></b>" Target for Tetracyclines?<b><div>Protein synthesis</div></b><br> "Target for&nbsp;<b><span style=""font-weight: 400;"">Nitrofurantoin</span></b>"<b><div>Protein synthesis</div></b><br> "Target for&nbsp;<b><span style=""font-weight: 400;"">Macrolides?</span></b>""<span style=""font-weight: 700;"">Protein synthesis<br></span>" Target for Fusidic acid?"<span style=""font-weight: 700;"">Protein synthesis</span>" Target for Doxy<b>clycline?</b>Protein synthesis Side effect of Doxy<b>clycline?</b>"<b><ul><li><div><span style=""font-weight: 400;"">GI upset</span></div></li><li><div><span style=""font-weight: 400;"">Photosensitivity</span></div></li><li><div><span style=""font-weight: 400;"">muscle weakness</span></div></li><li><div><span style=""font-weight: 400;"">bone and teeth development</span></div></li></ul></b>" Side effect of tetracyclines?"<ul style=""font-weight: 700;""><li><div><span style=""font-weight: 400;"">GI upset</span></div></li><li><div><span style=""font-weight: 400;"">Photosensitivity</span></div></li><li><div><span style=""font-weight: 400;"">muscle weakness</span></div></li><li><div><span style=""font-weight: 400;"">bone and teeth development</span></div></li></ul>" Key facts of Tetracylines?"<b><ul><li><div><span style=""font-weight: 400;"">30s ribosome</span></div></li><li><div><span style=""font-weight: 400;"">due to bone and teeth development side effect DO NOT give to pregnant women or children</span></div></li></ul></b>" Side effects of Nitrofurantoin?"<b><ul><li><div><span style=""font-weight: 400;"">GI upset</span></div></li><li><div><span style=""font-weight: 400;"">pulmonary toxicity</span></div></li><li><div><span style=""font-weight: 400;"">peripheral neuropathy</span></div></li></ul></b>" Key facts of&nbsp; Nitrofurantoin?"<b><ul><li><div><span style=""font-weight: 400;"">50 ribosome</span></div></li><li><div><span style=""font-weight: 400;"">Used to treat UTIs</span></div></li></ul></b>" Name a type of Macrolides?"<b><div><span style=""font-weight: 400;"">Erithromycin, clarithromycin</span></div></b><br>" Side effect of Macrolides?"<b><ul><li><div><span style=""font-weight: 400;"">GI disturbance and overgrowth</span></div></li></ul></b>" Side effect of Erithromycin?"<b><ul><li><div><span style=""font-weight: 400;"">GI disturbance and overgrowth</span></div></li></ul></b>" Side effect of clarithromycin?"<b><ul><li><div><span style=""font-weight: 400;"">GI disturbance and overgrowth</span></div></li></ul></b>" Key facts of Macrolides?<b><br></b>"<b><ul><li><div><span style=""font-weight: 400;"">50S ribosome</span></div></li><li><div><span style=""font-weight: 400;"">alters ECG - long QT syndrome</span></div></li></ul></b>" Key facts of Fusidic acid?"<b><ul><li><div><span style=""font-weight: 400;"">Topical steroid that treats Staph.a skin infections</span></div></li></ul></b>"